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Katja Petzold

@katjapetzold.bsky.social
630 followers 479 following 76 posts

RNA moving faster than the blink of an eye! (By NMR) Professor @Uppsala University More @ PetzoldLab.com

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Reposted by Katja Petzold
Emma R Andersson @anderssonlab.bsky.social · 23/09/2026
🧬 Preprint! 🧵 Our goal is to genetically manipulate every embryonic germ layer to enable high throughput in vivo studies. We previously showed mouse ectoderm can be targeted by amniotic injection, enabling cell-specific manipulation, lineage tracing, and knockouts. But how to reach mesoderm?
Schematic of method developed and application. At embryonic day 7.5, a lentiviral library carrying unique 30-nucleotide barcodes and a fluorescent reporter is injected into the mouse exocoelomic cavity. An E8 embryo cross-section shows that this cavity is continuous with the intraembryonic coelomic cavity, allowing the virus to reach and barcode mesodermal progenitors, including lateral plate and paraxial mesoderm.
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Reposted by Katja Petzold
Magdalena Skipper @magdalenaskipper.bsky.social · 02/07/2026
Too many of us repeat the statement that trust in science is falling. Is it really the case? The data don’t support this conclusion in a straight forward way. Science may have an influence & comms problem more than a trust problem, in fact… but it’s complex 👇🏻 🧪 www.nature.com/articles/d41...
nature.com
Have people stopped trusting science? The data tell a surprising story
Some say there’s a global crisis of trust — but research reveals where the real problems lie.
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Katja Petzold @katjapetzold.bsky.social · 23/06/2026
Short visit at the amazing @ccpnmr.bsky.social meeting in Bath. 🥵 temperatures outside and ❤️‍🔥 science. Dynamics, computation and what brings the future! Big thanks to Geerten Vuister & @ccpnmr.bsky.social team and hopefully many more years of this well needed initiative for the #NMR community 👏👏👏
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Katja Petzold @katjapetzold.bsky.social · 23/06/2026
I still have trouble to believe it #ERCAdG 🤩! We celebrated it a lot!! Big thanks to all future and current lab members and the evaluators! Off we go trying to understand what #RNA #dynamics (by #NMR and #probing) means in cellular regulation, send me a message if you want to join our journey 🚀.
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Katja Petzold @katjapetzold.bsky.social · 04/06/2026
Just leaving this here: ⚡️make love not war ❤️
m.youtube.com
NENA | 99 Luftballons [1983] [Offizielles HD Musikvideo]
YouTube video by NENA
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Katja Petzold @katjapetzold.bsky.social · 20/05/2026
I appreciate the Elsevier Journal Methods to take clear and fast action in terms of falsified data and also marks it clearly! Way to go. 👏 Other papers from the same author with same/similar data @natureportfolio.nature.com Scientific Reports is still happy out there...
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Katja Petzold @katjapetzold.bsky.social · 11/05/2026
The A-minor switch - check out our latest preprint (link below)
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Katja Petzold @katjapetzold.bsky.social · 11/05/2026
Imagine if one of RNA’s most common 3D contacts could switch off and on. We identified the A-minor switch that can reversibly “escape” their tertiary contacts, revealing a dynamic regulatory layer in RNA structure (shown by NMR & Cryo-EM and assayed in ribosomes). #RNA #NMR #dynamics #ribosome
biorxiv.org
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Katja Petzold @katjapetzold.bsky.social · 08/05/2026
curious about dynamic states in DNA or better methods to detect them? Have a look at our recent work using 1H R1ρ RD NMR on hoogsteen to WCF equilibrium.
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Reposted by Katja Petzold
CCPN @ccpnmr.bsky.social · 06/05/2026
Registration for the 2026 CCPN Conference in Bath from 22-24 June is now open at ccpn.ac.uk/outreach/con.... Join us for some exciting talks on dynamics and how to link NMR data with MD, plus many opportunities to get to know new people and catch up with old friends. Hope to see lots of you there!
ccpn.ac.uk
Conferences - CCPN - Collaborative Computing Project for NMR
The annual CCPN conference usually takes place in the summer and is specifically aimed at PhD students and post-docs (predominantly from the UK).
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Katja Petzold @katjapetzold.bsky.social · 06/05/2026
that is kind of cool: #RNA
academic.oup.com
Omnivore RNA pyrophosphatase: a versatile enzyme that efficiently removes diverse protecting groups from the 5′ end of RNA
Abstract. The 5′ ends of messenger RNAs typically are shielded from ribonuclease attack by protecting groups of various kinds, such as a canonical or nonca
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Reposted by Katja Petzold
icmrbs2026.bsky.social @icmrbs2026.bsky.social · 21/04/2026
Oral Abstract Submission Deadline – April 30! The countdown is on! There’s still time to submit your oral abstract for ICMRBS 2026 and contribute to an exciting and high-quality scientific program.
Davos mountain landscape in the background with the ICMRBS Logo in front and the written Text: Oral Abstracts submission Deadline April 30
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Katja Petzold @katjapetzold.bsky.social · 09/04/2026
Deadline for oral talk abstract submission is 30th of April, don't miss it! Beautiful place 🌄, great science 🔭 and a beer 🍻 tent after the talks
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Katja Petzold @katjapetzold.bsky.social · 18/03/2026
Want to know more about targeted enhancement of #NMR (by #DNP) signal for #RNA? Have a look at our latest work @pnas.org: Happy for feedback, interest & discussions 🤓
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Katja Petzold @katjapetzold.bsky.social · 18/03/2026
Finally we have the storry finished :)
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Reposted by Katja Petzold
Magnetic Resonance News @nmr900.bsky.social · 04/02/2026
PhD and Postdoctoral researcher positions at the RNA Structural Biology & Biophysics Laboratory, Uppsala University, Sweden, Prof Katja Petzold @katjapetzold.bsky.social (incl solid-state / solution NMR, Cryo-EM) Postdoc: www.uu.se/om-uu/jobba-... PhD: www.uu.se/om-uu/jobba-... #NMRjobs #NMRchat 🧲
PhD and Postdoctoral researcher positions at the RNA Structural Biology & Biophysics Laboratory, Uppsala University, Sweden, Prof Katja Petzold
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Katja Petzold @katjapetzold.bsky.social · 06/02/2026
beautfil review by @bussigio.bsky.social and Sanguinetti!
m.rnajournal.cshlp.org
RNA | Mobile
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Katja Petzold @katjapetzold.bsky.social · 03/02/2026
Interested in RNA structural biology/dynamics/biophysics and how they explain RNA regulation? Want to push further and this this in cells? Join our lab: 1 PhD and 1 Postdoc position (apply via links) www.uu.se/om-uu/jobba-... www.uu.se/om-uu/jobba-... #NMR #RNA #biophysics
uu.se
Postdoktortjänst inom Excellenscentrat Livets Kemiska Mekanismer vid Uppsala universitet - Uppsala universitet
Postdoktortjänst inom Excellenscentrat Livets Kemiska Mekanismer vid Uppsala universitet, Institutionen för kemi - LV, Uppsala universitet
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Katja Petzold @katjapetzold.bsky.social · 28/01/2026
the pyramid scheme of publishing... : " But publishers have an economic incentive to accept even subpar papers authored by guest editors, the researchers write, because guest editors work for free and recruit other authors to contribute to special issues." from: www.science.org/content/arti...
science.org
Some guest editors pack special issues with their own articles
Thousands have penned more than one-third of a journal issue, raising conflict-of-interest concerns
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Katja Petzold @katjapetzold.bsky.social · 16/01/2026
Trump: “I raise tolls on everyone opposing Greenland to become American.” Me (Swe/Ger): bring it on! A bit of hardship is nothing for the right thing to do. If we just could solve the Ukrainian occupation so by Russia so simply.
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Katja Petzold @katjapetzold.bsky.social · 02/12/2025
Thanks @curiousdina.bsky.social for your amazing talk! I learned a lot and just shocked my first year students with eukaryotes are probably coming from archea :) So cool so many different subjects covered! 🤩 Happy to have had you at @cml-uu.bsky.social
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Reposted by Katja Petzold
Bussi Lab @bussilab.org · 30/10/2025
Our work presented today at the www.youtube.com/@CASPRNASIG online seminar! @bussigio.bsky.social will report on the #CASP16 solvation challenge and 2D ensemble reconstructions using #DMS data
youtube.com
CASP RNA SIG
Welcome nucleic acid enthusiasts to the Special Interest Group (SIG) focused different aspects of nucleic acid 3D structure prediction, including but not limited to obtaining experimental data, buildi...
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Reposted by Katja Petzold
Mark A. Hanson @hansonmark.bsky.social · 30/10/2025
And don't forget, labs in the UK and Europe can donate to the Cambridge side of FlyBase through this link: www.philanthropy.cam.ac.uk/give-to-camb...
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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Katja Petzold @katjapetzold.bsky.social · 30/10/2025
One more paper by the “in-cell” NMR person looking weird. pubpeer.com/publications...
pubpeer.com
PubPeer - Biophysical and transcriptomic characterization of LL-37-der...
There are comments on PubPeer for publication: Biophysical and transcriptomic characterization of LL-37-derived antimicrobial peptide targeting multidrug-resistant Escherichia coli and ESKAPE pathogen...
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Reposted by Katja Petzold
Elisabeth Bik @elisabethbik.bsky.social · 23/10/2025
Competition @kaggle.com: Scientific Image Forgery Detection Who can develop the best model to detect copy/move forgeries in biomedical images? #ImageForensics www.kaggle.com/competitions...
kaggle.com
Recod.ai/LUC - Scientific Image Forgery Detection
Develop methods that can accurately detect and segment copy-move forgeries within biomedical research images.
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Reposted by Katja Petzold
Oded Rechavi @odedrechavi.bsky.social · 16/10/2025
The adrenaline is still kicking from the incredible enthusiasm and support, everybody who invites a friend to try q.e.d today gets a free physiological relevance! 🍷
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Reposted by Katja Petzold
The Daily Show @thedailyshow.com · 09/10/2025
The following is REAL footage from Portland, 2025. Viewer discretion is advised.
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Katja Petzold @katjapetzold.bsky.social · 10/10/2025
When I learned about the cruelties of SS and Nazi's in school (I'm german) I always wondered, how this could happened... I never imagined seeing it happening again and getting the explanation in front of my eyes...
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Reposted by Katja Petzold
Christopher Webb @cwebbonline.com · 10/10/2025
Sometimes we need a moment, but if you tune out completely, they win. Fascism doesn’t need your support, just your silence.
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Katja Petzold @katjapetzold.bsky.social · 10/10/2025
Do current publishing and carreer assessment practices limit scientific progress? Journals basically evaluate your recent citation numbers when you ausbmit to the editorial board... HOWEVER: novel research areas have low number of participants and publications -> low number of citations
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Katja Petzold @katjapetzold.bsky.social · 07/10/2025
It’s out :) you thought it was weird for DNA to be 1% in a Hoogsteen base pair instead of a Watson-Crick-Franklin one? Well there is more:
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Katja Petzold @katjapetzold.bsky.social · 25/09/2025
Big thanks to my group of doing all this wonderful research 😍 and to @uu.se and my department IMBIM for nominating me and the Fernström price organization. www.uu.se/en/news/2025...
uu.se
Eric K. Fernström Swedish Prize awarded to Katja Petzold - Uppsala University
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Reposted by Katja Petzold
Edouard Hannezo @ehannezo.bsky.social · 19/09/2025
Core achievement unlocked!! Congrats to Fabrizio amd all authors!!
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Katja Petzold @katjapetzold.bsky.social · 12/09/2025
please #NMR #RNA community, carefullly review papers! These are 2 blatantly manipulated papers that should have never gone through the peer-review system. Same for editors. If not us, who will stop this?? big thanks @elisabethbik.bsky.social 😍 without you we wouldn't have scienc left!
pubpeer.com
PubPeer - In-cell NMR reveals the first direct observation of endogeno...
There are comments on PubPeer for publication: In-cell NMR reveals the first direct observation of endogenous interaction between HIV Tat protein and Tat RNA aptamer in human cells (2025)
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Reposted by Katja Petzold
Max-Planck-Gesellschaft @maxplanck.de · 09/09/2025
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
Call for Applications / Ausschreibung
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Reposted by Katja Petzold
Marcel Swart @marcelswart.bsky.social · 11/09/2025
#chemjobs #compchem Assistant Professorship in Theoretical Chemistry at University of Cambridge www.ch.cam.ac.uk/job/52637
ch.cam.ac.uk
University Assistant Professor | Yusuf Hamied Department of Chemistry
Applications are invited for a University Assistant Professor to work in the area of theoretical chemistry, broadly defined, to be taken up in October 2026 (or earlier, by agreement). The successful a...
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Katja Petzold @katjapetzold.bsky.social · 11/09/2025
@rfsu.bsky.social For all Swedes: please sign this petition, so our kids also have in the future SexEd in school. Thanks! www.rfsu.se/engagera-dig...
rfsu.se
Rädda sexualundervisningen! | RFSU
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Reposted by Katja Petzold
Christian Steinmetzger @stonebutcher.bsky.social · 08/09/2025
Check out our new method for targeted DNP-enhanced NMR of RNA using site-directed spin labeling, now live as a preprint on ChemRxiv: doi.org/10.26434/che... A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.
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Katja Petzold @katjapetzold.bsky.social · 09/09/2025
New preprint out! We introduce an AsymPol spin labeling for RNA, enabling targeted DNP NMR with up to 27× sensitivity boost at low concentrations. Read here: chemrxiv.org/engage/chemr... #RNA #NMR #DNP #StructuralBiology #SpinLabeling #ChemRxiv
chemrxiv.org
Site-Directed Spin Labeling with the Bis-Nitroxide AsymPol Enables Targeted DNP MAS NMR of RNA
Dynamic nuclear polarization (DNP) enhances NMR sensitivity by transferring electron spin polarization to nuclei, providing structural and biophysical insights into complex biomolecules at low concent...
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Katja Petzold @katjapetzold.bsky.social · 15/08/2025
I am looking at a publication and wonder if some of the images are manipulated/manifactured. Does anyone have a good image checking tool? In days of AI such a thing should exist... (me: academic in Sweden, if that helps with licenses) THANKS!
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Katja Petzold @katjapetzold.bsky.social · 01/08/2025
What #biophysical process steers one #microRNA to select one #mRNA over another? Trying to decipher this for miR-34a: our long standing efforts with the labs of @anderssonlab.bsky.social and Alan Chen (SUNY RNA) are finally out: academic.oup.com/nar/article/... Thanks for the exciting journey 🤩😍
academic.oup.com
Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy
Abstract. MicroRNAs (miRs) regulate gene expression post-transcriptionally by guiding Argonaute (AGO) proteins to target mRNAs. Efficiently predicting the
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Katja Petzold @katjapetzold.bsky.social · 27/06/2025
Very interesting paper: RNA adjusting to starvation
academic.oup.com
Cells resist starvation through a nutrient stress splice switch
Abstract. Introns are common features of eukaryotic genes, typically removed through splicing to produce functional RNAs. In yeast, some introns play roles
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Reposted by Katja Petzold
Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 04/05/2025
While this paper looks interesting, let me just say (again) that (essentially all) NMR ensembles in the PDB are NOT thermodynamic ensembles or meant to represent these. They are "uncertainty ensembles" and using them to benchmark machine learning (or other) models of dynamics is not a good idea.
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Katja Petzold @katjapetzold.bsky.social · 05/05/2025
yeah! our paper is out! Congratulations to David and Emma 🥳
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Katja Petzold @katjapetzold.bsky.social · 28/04/2025
Want to work in amazing environment? I moved to my current place two years and I couldn't be happier! We are looking for a Associate Professor (wit possibility to promotion to Full Professor)
uu.se
Senior lecturer in medical biochemistry - Uppsala University
Senior lecturer in medical biochemistry , Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University
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Katja Petzold @katjapetzold.bsky.social · 25/04/2025
Lab alumnus Marvin Albers is going places! Congratulations 🤩
ixa.nl
Marvin Albers and Tom Grossmann (Vrije Universiteit Amsterdam)Marvin Albers and Tom Grossmann (Vrije Universiteit Amsterdam) – IXA
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Katja Petzold @katjapetzold.bsky.social · 25/04/2025
few days left to join the GRC! (and 2 spots left for selected talks). Looking forward to discuss computational approaches in NMR with you in the beautiful mountains of Switzerland #NMR
grc.org
2025 Computational Aspects of Biomolecular NMR Conference GRC
The 2025 Gordon Research Conference on Computational Aspects of Biomolecular NMR will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
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Katja Petzold @katjapetzold.bsky.social · 11/04/2025
In Swedish: how the increasing rent (taken by the state) is bankrupting Swedish universities…
unt.se
KARL RYDÅ: Ekonomisk utpressning av universitetet och biblioteken
Pengakarusellen där staten ger med ena handen och tar med den andra är lika ovärdig som ologisk.
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Katja Petzold @katjapetzold.bsky.social · 04/04/2025
big congratulations 👏! What an amazing project 🤩
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Katja Petzold @katjapetzold.bsky.social · 04/04/2025
Curious of how computation or machine learning can bring NMR further?? Come to beautiful Switzerland and the GRC! Still a few spaces left.
grc.org
2025 Computational Aspects of Biomolecular NMR Conference GRC
The 2025 Gordon Research Conference on Computational Aspects of Biomolecular NMR will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
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