This textbook covers key concepts of embryology and principles of development in an understandable but detailed enough pace for advanced undergraduate students. Intended audience is advanced (3rd/4th ...

The human brain is incomplete at birth, with streams of late-born interneurons migrating into the postnatal cortex. This process is absent in rodents, limiting mechanistic investigation to post-mortem...

Faini et al. develop CLOK, a method that labels neurons across a spectrum of colors according to when they were born, allowing successive generations of brain cells to be tracked as they take shape in...

Tracking the biological age of grafted organs suggests that donor pools could be expanded to boost organ availability.

Type 2 inflammation trains nerve- and airway-associated macrophages to confer disease tolerance against lethal influenza by limiting immunopathology and promoting tissue repair without enhancing viral...

Vinsland et al. provide a single-cell and spatial transcriptomics atlas of postconceptional week 5–13 human meninges and perform comparative studies with meningioma data.

Naomi Moris is a group leader at the Francis Crick Institute in London, UK. Naomi's lab uses in vitro embryo models derived from stem cells to study the early stages of human development and understan...

Although tumor protein p53 (TP53) mutations are among the most common lesions in epithelial cancers, how p53 loss drives unrestrained clonal expansion remains unclear. Working with mouse epidermis, we...

Ribosome hibernation helps cells survive stress by reversibly silencing translation and preserving ribosomal complexes. Although well characterized in bacteria and eukaryotes, archaeal hibernation rem...

Summary: Single cell RNA-sequencing establishes core components of the gene regulatory network that drive Nestin-expressing progenitor to inhibitory neuron differentiation in the developing mouse and ...

This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…

The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.

Angiosperm seed formation requires the coordinated development of the products of double fertilization—the embryo and the endosperm. The endosperm mediates efficient nutrient transfer from surrounding...