The authors show human embryo lineage specification in the blastocyst is driven by differential FGF/ERK signaling, which segregates yolk sac-fated hypoblast and embryonic epiblast. They establish naïv...

What happens when the greatest strengths of science, such as openness, humility, self-criticism and self-correction, are exploited for political gain? This Perspective calls for scientists to affirm t...

Summary: The transcriptional regulators SOX2 and NR2F1 drive the development of the visual thalamus. Mutations in these genes cause visual impairment in humans.

ABSTRACT. First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Kishalay Ghos...

Please complete this form if you are a PI recruiting graduate students for a Fall 2026 start. If you are NOT recruiting, feel free to share the response sheet with prospective students looking for lab...

An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms

Postdoc in the molecular mechanisms and behavioral consequences of normal and abnormal mouse spinal cord development.

Engineering Life 2025, biological forces, force spectroscopy, measuring forces, developmental forces, molecular motors, forces in morphogenesis, cytoskeleton, DNA mechanics, bionanotechnology

An analysis of millions of scientific papers and patents shows that the further a researcher or inventor moves from their previous work, the less cited their latest work will be.

A growing body of evidence emphasizes the presence of significant intra-tumoral phenotypic diversity and plasticity within brain tumors. Inherent plasticity introduces an additional layer of intricacy...

Meet the Davies Lab, based in the Centre for Discovery Brain Sciences, the University of Edinburgh.

Physical forces are emerging as important contributors to a wide diversity of biological processes across multiple scales and contexts. The development of the nervous system is infuenced by mechanical...

Antibodies (Ab) are essential for detecting specific epitopes in microscopy and genomics, but can produce artifacts leading to erroneous interpretations. Here, we characterize a novel artifact, Ab-tra...

First of its Kind Study Identifies Metabolic Defects in Dravet Syndrome