The mammalian liver possesses a regenerative capacity that is unmatched by any other organ. Following injury, liver epithelial cells can proliferate or even change their identity, enabling the organ t...

Tissue resilience requires tight coupling between cell proliferation, growth, and death.1,2,3,4It is assumed to be based on compensatory proliferation…

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

Studying morphogen gradient-based tissue patterning in silico while accounting for biological variability remains challenging. Here, we present a MATLAB-based protocol for simulating steady-state morp...

Nature Physics - Carcinoma subtypes are normally linked to specific genetic alterations, but tissue mechanical changes also play a role. Now, aberrant morphologies resembling bladder carcinoma are...

In 2025, Inserm is opening up 67 tenure positions (Researchers junior and senior), covering disciplines dedicated to biomedical research and human health. Registration deadline: January 20, 2025.

The capacity of our tissues to cope with external and internal stress relies on the tight coupling between cell proliferation, cell growth and cell death. This coupling is assumed to be based on compe...

The coordination of cell proliferation, migration, and differentiation is crucial for organogenesis

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