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Robert Grosse @ grosselab

@grosselab.bsky.social
1.4K followers 842 following 148 posts

all things cytoskeleton - nuclear actin dynamics and genome - nucleoskeleton and nuclear organisation - cancer cell invasion and pharmacology @University of Freiburg

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Reposted by Robert Grosse @ grosselab
Michael Way @drmichaelway.bsky.social · 18h
Looking for a PhD? @crick.ac.uk PhD applications for next year are open. 4 year program with lots of outstanding projects on offer. If you are interested in viral host interactions, cytoskeleton, cell bio, live cell imaging - see Way lab project + video. plz repost www.crick.ac.uk/careers-and-...
crick.ac.uk
PhD student positions
PhD projects for the 2027 Crick PhD programme.
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Reposted by Robert Grosse @ grosselab
Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026
Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share
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Reposted by Robert Grosse @ grosselab
Ben Engel @cellarchlab.com · 18/09/2026
Duuude! What indeed?? Airway epithelia have 100s of cilia per cell (not one or two), and they aren’t 10x longer than the cells themselves. Then there’s that mysterious purple layer below… made of mitochondria? And the motion😵‍💫. It looks like #AIslop may have taken over the small world competition? 🔬🧪
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Antoine Molaro @antoinemolaro.bsky.social · 09/09/2026
Hello World ! Reminder about our open postdoc position 🧪🧬 Reviewing applications until October - get in touch to know more about what's hot in the lab these days ! Application details in the post below 👇👇 #EvoEpi #MolaroLab #watwat #ERC
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Alan Brown @alanbrownhms.bsky.social · 10/09/2026
Millions of beating cilia keep airways clean. At the base of each is the transition zone (TZ), a gate that controls which proteins enter and leave. In our paper out today in Science, we used cryo-FIB-ET to image the TZ inside human airway cells www.science.org/doi/10.1126/...
science.org
In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia
The ciliary transition zone (TZ) regulates ciliary proteome composition, yet its molecular architecture, protein content, and contribution to motile ciliopathies remain poorly defined. We applied in situ cryo-electron tomography and subtomogram averaging ...
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Reposted by Robert Grosse @ grosselab
Christophe 🔬 Leterrier @christlet.bsky.social · 17/09/2026
Hallelujah! Papers written by an AI and reviewed by an AI can finally be read by an AI, fulfilling the prophecy of the Great AI Circlejerk
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Felix Mikus @fmikus.bsky.social · 11/09/2026
Are you interested in the nuclear envelope and are still lacking a dye for it? Try the lectin concanavalin A in #U-ExM! Together with @baukjeje.bsky.social, @gautamdey.bsky.social and @dudinlab.bsky.social and many collaborators sharing species with us we explored the versatility of this dye
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RWedlichSoldner.bsky.social @rwedlichsoldner.bsky.social · 24/08/2026
It's been a while in the making, but finally out:😂🥳 We’re excited to share our new work with H. Pavenstädt, D. Braun, M. Krahn, P. Bieling and @raunser-lab.bsky.social on INF2 and global actin remodeling! Read the story here: www.biorxiv.org/content/10.6... #Actin #Cytoskeleton #CellBiology #INF2
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sigtrans.bsky.social @sigtrans.bsky.social · 31/08/2026
Registration is open for the #CellCommSummit 2026 (29𝐭𝐡 𝐌𝐞𝐞𝐭𝐢𝐧𝐠 𝐨𝐧 #Signaltransduction)! The conference will take place from November 2 to 4, 2026 at the Leonardo Hotel in Weimar, Germany. Meet our Keynote Speaker Julia Gross (Potsdam) in Session E "Tumor Cell Biology",
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Reposted by Robert Grosse @ grosselab
Giovanni D’Angelo @giodang.bsky.social · 28/08/2026
Registration is still open for the EPFL Latsis Symposium 2026, "Decoding the Cell: Modeling, Predicting, and Engineering Cellular States." 29–30 Oct, Olympic Museum, Lausanne. Quake, Haniffa, Engelhardt, Liberali, Paluch, Kundaje and more. Abstracts close 15 Sept. latsis2026.epfl.ch/event/1/
latsis2026.epfl.ch
EPFL Latsis Symposium 2026
Join us in Lausanne to connect with the global community shaping the future of cell understanding and engineering.
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Andy Wolfe @andrewlwolfe.bsky.social · 27/08/2026
What a moment! After many years of preclinical and clinical testing, the FDA approved the first Ras inhibitor to treat pancreatic cancer. What an inflection point in the history of this deadly disease, the Ras scientific field, and hope for cancer patients. www.nytimes.com/2026/08/26/s...
nytimes.com
F.D.A. Approves the Drug Daraxonrasib That’s Poised to Transform Pancreatic Cancer (Gift Article)
In a key clinical trial, patients who got the pill, daraxonrasib, lived twice as long as those who got chemotherapy.
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Reposted by Robert Grosse @ grosselab
SSHRC | CRSH @sshrc-crsh.canada.ca · 18/08/2026
New funding opportunity for doctoral researchers: We’re pleased to expand our partnership with the @dfg.de through the German-Canadian International Research Training Groups joint initiative. Learn more and how to apply: sshrc-crsh.canada.ca/en/funding/o...
Canadian flag and German flag.

New funding opportunity. International research training group joint initiative.
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Deutsche Forschungsgemeinschaft @dfg.de · 13/08/2026
Schon dabei? Noch bis zum 15. September Projekt-Fotos oder -Illustrationen einsenden. 👇
Grafik: Fotowettbewerb DFG-Kalender 2027. Fpr unseren Wandkalender werden 12 Motive zum Thema Dynamik gesucht. Teilnehmen können alle aktuell geförderten Projekte. Jetzt Foto oder Grafik einreichen! Einsendeschluss 15. September 2026
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Journal of Cell Science @jcellsci.bsky.social · 11/08/2026
Our 'Cell Science at a Glance' articles are short primers that act as an introduction to an area of cell biology. Perfect if you're new to a field, or want to find out the latest on a particular topic. Check out the full list at: tinyurl.com/4c8e8m97 #cellbiology #community #notforprofit
A collage showing a selection of recent Cell Science at a Glance posters
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Markus Elsner @markuselsner.bsky.social · 11/08/2026
Only 3 spots left ...
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Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 11/08/2026
📢 This December, we're hosting the Epigenetics Meeting in Freiburg, 🇩🇪. Now in its next edition, this biennial meeting has earned an international reputation as a stimulating and scientifically rigorous event in the #chromatin and #epigenetics field. Join us: events.ie-freiburg.mpg.de/register
Poster for the Max Planck Freiburg 8th Epigenetics Meeting from 2 to 4 December 2026 listing speakers, keynote, registration details, and venue at MPI of Immunobiology & Epigenetics
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Reposted by Robert Grosse @ grosselab
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 06/08/2026
Come join us at ETH!
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Rita Strack @ritastrack.bsky.social · 07/08/2026
Nature Reviews Molecular Cell Biology is hiring! springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor, Nature Reviews Molecular Cell Biology
Job Title: Associate or Senior Editor, Nature Reviews Molecular Cell Biology Location: Beijing, Shanghai or Madrid, Hybrid Working Model Application Deadline: Aug 24th, 2026 About Springer Nature Spri...
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Reposted by Robert Grosse @ grosselab
EMBO @embo.org · 06/08/2026
Interested in a cross-scale understanding of #mechanobiology? Join the EMBO Workshop "Forces across scales" in Porto, Portugal, 27–30 April 2027. Deadline: 1 December 2026 meetings.embo.org/event/27-forces-s… #EMBOforces #EMBOevents 🧪
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CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · 05/08/2026
📣 #JobAlert The @biologyunifreiburg.bsky.social of @uni-freiburg.de invites applications for a position as Head of the Life Imaging Center (LIC) – the core facility for light microscopy. ❗ Application Deadline: 6 September, 2026 🔗 kurzlinks.de/2126 #Biology #LightMicroscopy #Imaging
Job alert for Head of Life Imaging Center with the application deadline (6 September).
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Cees Dekker @ceesdekker.bsky.social · 22/07/2026
We built a a self-dividing synthetic cell ! Check out this #CDlab preprint on BioRxiv: www.biorxiv.org/content/10.6... Great work by 1st author Charu Sharma who encoded dynaminA in a genome and expressed that in liposomes that then divide into daughter cells! Collaboration with Koenderink lab!
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KleineVehnLab @kleinevehnlab.bsky.social · 23/07/2026
5/5 Our paper reveals how young lateral roots establish their initial growth direction. Besides, it also highlights something equally important: Science is cumulative, collaborative, and built through mentorship — from group leaders to PhD candidates to undergraduate students.
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Jan Lohmann @meristemania.bsky.social · 20/07/2026
Awesome Symposium coming up @cosheidelberg.bsky.social in September! Check it out - registration is free. www.cos.uni-heidelberg.de/en/cos-sympo...
cos.uni-heidelberg.de
COS Symposium 2026 - Centre for Organismal Studies
Venue: Lecture hallCentre for Organismal Studies – Heidelberg UniversityIm Neuenheimer Feld 230
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Floris BOSVELD @florisbosveld.bsky.social · 21/07/2026
Doing a Master or PhD and interested in Developmental Biology? Join the free Institut Curie developmental biology course in beautiful Paris this fall! Great speaker lineup, check: training.institut-curie.org/courses/deve... Registration deadline Sept. 18 2026.
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Reposted by Robert Grosse @ grosselab
SourjikLab @sourjik-lab.bsky.social · 21/07/2026
Together with @thanbichlerlab.bsky.social, we are looking for an ambitious PhD student to develop fluorescence imaging for anaerobic bacteria. Check out this and other positions that are announced as a part of the M4C Excellence cluster here: stellenangebote.uni-marburg.de/jobposting/2...
stellenangebote.uni-marburg.de
Doctoral and Postdoctoral Researcher Positions in the Cluster of Excellence ‘Microbes for Climate’
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Henning Jessen @jessenlab.bsky.social · 21/07/2026
happy to share our new review with Adolfo Saiardi: Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies - Saiardi - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this c...
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Reposted by Robert Grosse @ grosselab
bogdanlab.bsky.social @bogdanlab.bsky.social · 18/07/2026
Join our team! The @bogdan_lab in Marburg is hiring a postdoctoral fellow and a doctoral student for studying innate cellular immune response to tumor cells and epidermal wounds in Drosophila. Apply: stellenangebote.uni-marburg.de/jobposting/4... stellenangebote.uni-marburg.de/jobposting/3...
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Danielle Beckman @daniellebeckman.bsky.social · 17/07/2026
This is not AI. This is real microscopy! 🔬 An intact gut, rendered transparent and imaged in 3D using light-sheet microscopy! 🤓 Looking inside organs to investigate where pathogens, immune cells, or disease processes may persist. More at: www.nature.com/articles/s41... Happy #FluorescenceFriday!
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Luke Lavis @rhodamine110.bsky.social · 17/07/2026
Excited to see this collaboration now in print. Dye chemistry meets AI-designed proteins. Three small, orthogonal tags; lifetime modulation; split versions. Request the free dyes at dyes.janelia.org www.science.org/doi/10.1126/...
science.org
De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging
Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...
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Ivaska Lab @ivaskalab.bsky.social · 16/07/2026
New paper alert! Michal Dibus and team show tensin-1 forms reversible condensates that act as reservoirs for adhesion proteins, tuning adhesion turnover and cell migration - a cool new role for phase separation in cell adhesion dynamics! Congratulations to the team 🎉! Paper here: bit.ly/4y9E8Xr
bit.ly
Adhesion-derived condensates control component availability to regulate adhesion dynamics - Nature Communications
Integrin adhesions allow dynamic cell-matrix interactions to regulate cell behaviour. Here, the authors reveal that tensin 1, a multidomain adaptor protein, forms condensates in cells that act as reve...
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Robert Grosse @ grosselab @grosselab.bsky.social · 09/07/2026
interesting paper from the group of @arpcomplex.bsky.social on how chromatin decompaction modulates nuclear shape and actin dynamics for T-cell function doi.org/10.1091/mbc....
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Reposted by Robert Grosse @ grosselab
Barbara Mellone 🇺🇦 @centromellone.bsky.social · 26/06/2026
Timeline cleanser ⚽️
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Reposted by Robert Grosse @ grosselab
Peter Lenart @plenart.bsky.social · 28/06/2026
It is meiotic recombination!
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Robert Grosse @ grosselab @grosselab.bsky.social · 26/06/2026
I cannot ask for more, my seminar advertised together with ice cream in the cafeteria of the IMG in Prague. I had a great time meeting great scientists. Thanks Libor Macůrek for this invitation.
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Ben Engel @cellarchlab.com · 24/06/2026
Beautiful chromatin confetti 🧬🎊 from gently lysed archaea cells. Definitive proof for the in vivo relevance of hypernucleosomes, with more compacted chromatin during stationary phase. This is big for chromatin evolution! Go Sveta & gang! You are trailblazers!! #TeamTomo #ArchaeaSky 👩‍🔬🧪
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David Solecki @so-lets-kilab70.bsky.social · 22/06/2026
What if you could watch chromatin change in live neurons…..IN REAL TIME?Share if this is your dream! My lab is making biosensors to make chromatin visible as neurons wire into circuits & are hiring an Associate Scientist to build, not just execute. Apply: stjude.wd1.myworkdayjobs.com/stjude/job/M...
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Abby Buchwalter @abbybuch.bsky.social · 21/06/2026
After some good funding news, we are hiring! Looking for a postdoc to join our team and lead our explorations into transposon repression by the nuclear lamina. Check out the full ad on our lab website at buchwalter-lab.github.io/postdoc-ad.pdf + contact me to learn more!
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Guillaume Thibault @gthibault.bsky.social · 21/06/2026
NTU's School of Biological Sciences is hiring faculty, Assistant Professor to Full Professor. The environment is collaborative and the start-up funding is genuinely generous. Four research areas. Campus visits 28 Sep to 2 Oct 2026. Apply here www.ntu.edu.sg/sbs/about-us...
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Elias Spiliotis @septinlab.bsky.social · 12/06/2026
Our newest review on septins as makers & breakers of membrane contacts in J Neurochem Fun writing with new PhD grad (and FASEB Septin Conference A/V Assistant Extrordinaire) TJ Holt Thanks @mcmurraylab.bsky.social @sergemostowylab.bsky.social for input. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Septins are a family of GTP-binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. G...
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Saravanan Palani @syncellbiolab.bsky.social · 12/06/2026
Our new paper in @plosbiology.org introduces IntAct-U-ExM enabling isoform-specific imaging of actin at nanoscale across yeast, mammalian cells & primary neurons. Fabulous work spearheaded by @anubhavdhar.bsky.social along with an amazing team! #actin #U-ExM journals.plos.org/plosbiology/...
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Robert Grosse @ grosselab @grosselab.bsky.social · 14/06/2026
Nice work "IntAct-U-ExM enables super-resolution imaging of isoform-specific actin networks across species": dx.plos.org/10.1371/jour... 👉endogenously tagged beta and gamma actin inside the nuclear compartment- how cool is that?!
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Science Magazine @science.org · 13/06/2026
Chikwe Ihekweazu, on the ground in the Democratic Republic of the Congo, discusses challenges of bringing the Ebola outbreak under control. scim.ag/3Qu7Xkl
scim.ag
‘Working without them is painful’: WHO’s Ebola chief reflects on U.S. colleagues’ absence
Chikwe Ihekweazu, on the ground in Congo, discusses challenges of bringing the outbreak under control
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Jens Schmidt @jenscs83.bsky.social · 11/06/2026
I am looking to recruit 2 postdoctoral fellows to the lab to work on a recently funded project focused on class switch recombination in B cells. If you are interested in immunology, gene expression, and RNA and protein single molecule imaging, please reach out (schmi706@msu.edu). Please share!
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Lara Krüger @lara-kruger.bsky.social · 09/06/2026
📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.
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Ali Shaib @alishaib.bsky.social · 01/06/2026
Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...
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Robert Grosse @ grosselab @grosselab.bsky.social · 20/05/2026
amazing
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Nature @nature.com · 15/05/2026
Half of laboratory mice are not what scientists think they are go.nature.com/437pTDZ
go.nature.com
Genetic survey exposes flaws in widely used mouse models
A survey of more than 300 mouse strains has found widespread discrepancies between how mutant mice are reported and their actual genetic make-up.
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Julia Lazzari-Dean @jlazzaridean.bsky.social · 12/05/2026
We invented “triplet tumbling microscopy” (TTM) to track protein-protein interactions in living cells! Tag your protein with GFP and see it interact with *untagged* binding partners www.biorxiv.org/content/10.6...
A cartoon overview of triplet tumbling microscopy, comparing data from bound and unbound samples.
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Proceedings of the National Academy of Sciences @pnas.org · 08/05/2026
Opinion piece: The peer review process and peer reviewers are severely strained. We propose a transparent universal credit system to incentivize #PeerReview. In PNAS Front Matter: ow.ly/6Ahb50YWblR #SciencePublishing #AcademicPublishing #ResearchEnterprise
Two people exchanging documents and coins.
Image credit: Dave Cutler (artist).
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Deutsche Forschungsgemeinschaft @dfg.de · 05/05/2026
Good News!📢 Die DFG hat vom 1. Januar bis 31. März 2026 insgesamt 43 Wissenschaftler*innen in die Programme der #Einzelförderung aufgenommen. Mehr zu den Projekten, Personen und ihren Einrichtungen: ➡️ www.dfg.de/de/aktuelles...
Tafel mit Auflistung unter der Überschrift: 43 Personen neu in der DFG-Förderung
25 im Emmy Noether-Programm
15 im Heisenberg-Programm
3 in die Reinhart Koselleck-Förderung
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