Sign in

Elias Spiliotis

@septinlab.bsky.social
1.5K followers 1.9K following 344 posts

Professor of Cell Biology (University of Virginia), Research Scientist. Science, music, sports and politics. Opinions are my own and not of my lab or university.

PostsRepliesMedia
Elias Spiliotis @septinlab.bsky.social · 23/09/2026
Tony’s Disco, Petersburg, VA This landmark opened its doors in 1970 and currently serves as a… steak house!?! Always a treat when Waze reroutes you through backroads.
000
Elias Spiliotis @septinlab.bsky.social · 15/09/2026
September is for Septins! #SeptforSeptins Time for septin spice lattes... and submitting your septin paper to the MBoC Special Issue: Cell Biology of Septins Still accepting papers @ascbiology.bsky.social www.molbiolcell.org/cell-biology...
molbiolcell.org
Molecular Biology of the Cell (MBoC)
062
Elias Spiliotis @septinlab.bsky.social · 26/08/2026
We're launching a search for two open-rank positions with preference for Assistant/Associate Professors in the Department of Cell Biology at University of Virginia. If you're a card-carrying cell biologist, consider applying here now: apply.interfolio.com/191024
static.klipy.com
Bill Belichick Looking For A New Job Meme
ALT: Bill Belichick Looking For A New Job Meme
01016
Elias Spiliotis @septinlab.bsky.social · 21/08/2026
That’s the most psychedelic science poster I have ever seen - let alone be part of. Inspired to raise my game.
081
Reposted by Elias Spiliotis
Journal of Cell Biology @jcb.org · 17/08/2026
Spotlight: @babliadhikary.bsky.social et al. (rupress.org/jcb/article/...) describe the role of PAK4 in vertex remodeling, thereby maintaining epithelial integrity and barrier function. @raghavan-thiaga.bsky.social and @kuba-sedzinski.bsky.social discuss the study: rupress.org/jcb/article/...
0135
Reposted by Elias Spiliotis
Subhojit Roy MD, PhD @roylab-ucsd.bsky.social · 18/08/2026
Ok, we know nothing about the brain "More than 80% of eliminated dendritic spines reappeared at their original locations after recovery [from hibernation]": www.science.org/doi/10.1126/...
science.org
Artificial hibernation reveals synaptic engram architecture associated with memory retention
Memories leave lasting physical changes at the synaptic level. Although stable, larger spines are thought to support memory, the high turnover of dendritic spines and the drifting of neuronal represen...
0172
Reposted by Elias Spiliotis
Anna Allen @akallen10.bsky.social · 17/08/2026
New NSF BIO solicitation is live.... this replaces the previous IOS, MCB, DEB solicitation www.nsf.gov/funding/oppo...
45883
Reposted by Elias Spiliotis
Brent Toderian @brenttoderian.bsky.social · 15/08/2026
“Scientists should stop trying to be neutral and instead embrace their values,”says a group of top climate scientists, including @katharinehayhoe.com. The neutrality myth is harming the reputation of science right when we need it most.” #ClimateCrisis Science isn’t neutral. It’s science.
cbc.ca
Prominent climate scientist argues it's time to ditch the 'myth of neutrality' | CBC Radio
Climate scientist Katharine Hayhoe talks to Bob McDonald about the polarization of science and why she thinks scientists should stop pretending to be neutral when it's our planet at risk.
371425482
Elias Spiliotis @septinlab.bsky.social · 15/08/2026
Innovation: Investigators innovate by modifying standard techniques to fit new contexts, overcome resource limits, or address unique constraints. This adaptive approach involves customizing tools or blending distinct research traditions…
210
Elias Spiliotis @septinlab.bsky.social · 14/08/2026
Mike D on Beasties sampling over 100 songs in Paul’s Boutique. www.musicradar.com/artists/i-do...
musicradar.com
“I don’t want to say The Beatles cleared it, but somebody at EMI or Apple. So whoever you were that did it, thank you. Thank you, Sir Paul”: Mike D on how the Beastie Boys got away with sampling five ...
Ahead of the release of his debut solo album, Mike D looks back at the audacious, anything-goes sampling ethos behind the Beastie Boys' magnum opus
000
Elias Spiliotis @septinlab.bsky.social · 13/08/2026
Hope to run into this fellow Charlottesvillian at some point and bow in appreciation. He strips down the nonsense like no other.
010
Reposted by Elias Spiliotis
Steve Ramirez @okaysteve.bsky.social · 11/08/2026
It was an honor to write this remembrance of Susumu Tonegawa (1939–2026) -- a scientist whose discoveries transformed biology and whose lab shaped generations of neuroscientists. I hope this piece captures even a small part of his remarkable legacy. www.nature.com/articles/s41...
nature.com
Susumu Tonegawa (1939–2026) - Nature Neuroscience
On 11 July 2026, neuroscience lost one of its most visionary scientists with the passing of Susumu Tonegawa at the age of 86. Across an extraordinary career spanning more than five decades, Tonegawa p...
28727
Reposted by Elias Spiliotis
Piali Sengupta @senguptalab.bsky.social · 11/08/2026
Highly cool. 'Cytoskeletal' proteins in the nucleus, 'synaptic' proteins in the cilium. Issue is going to be how to dissect exactly where each protein acts for specific phenotypes www.sciencedirect.com/science/arti...
sciencedirect.com
Nuclear proteome reveals microtubule-associated protein regulating fate and disease
Cellular differentiation and morphogenesis require the coordination between cytoskeletal remodeling and transcriptional programs, raising the question…
2235
Elias Spiliotis @septinlab.bsky.social · 10/08/2026
The Greeks are always ahead of their time…!
010
Elias Spiliotis @septinlab.bsky.social · 07/08/2026
Greatest thing since ketchup slice…
000
Reposted by Elias Spiliotis
michaeledward @michaeledward.bsky.social · 07/08/2026
Rest in peace to Country Joe McDonald, the legendary singer-songwriter, activist and frontman of Country Joe and the Fish, who has died at 84.
2313674625
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 06/08/2026
www.biorxiv.org/content/10.1... Structural basis for alpha-actinin inhibition of cooperative cofilin binding to actin filaments
063
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 04/08/2026
www.biorxiv.org/content/10.6... Mechanism of branched actin assembly at microtubule tips downstream of Adenomatous Polyposis Coli (APC) protein
0135
Elias Spiliotis @septinlab.bsky.social · 04/08/2026
Just found out about Carnegie Embryology's closing at Hopkins. I did my first grad school rotation there with Andy Fire & Yixian Zheng. And took the legendary Molecular Morphogenesis course. It was such a jolt. The smell of this place is still in my head. Sad. www.bizjournals.com/baltimore/ne...
bizjournals.com
Storied research institute leaves Hopkins campus after 100 years - Baltimore Business Journal
After over 100 years of research that led to a Nobel Prize and dozens of other discoveries, one of the world's top research institutions is leaving Baltimore.
020
Elias Spiliotis @septinlab.bsky.social · 01/08/2026
#NotOnMyBingoCard #PopeIsAPunkRocker www.vaticannews.va/en/pope/news...
vaticannews.va
Pope Leo XIV meets Patti Smith - Vatican News
On Friday morning, July 31, the Pope received Patti Smith, the singer-songwriter, poet, and artist, who—like him—is originally from Chicago.
020
Reposted by Elias Spiliotis
Journal of Cell Science @jcellsci.bsky.social · 28/07/2026
Carolyn Ott @hhmijanelia.bsky.social, Jennifer Lippincott-Schwartz & David Breslow @davidbreslowlab.bsky.social explain how recent advances have expanded our models of primary cilia disassemble and discuss emerging roles of altered disassembly in disease. journals.biologists.com/jcs/article/...
Schematic showing the mechanisms contributing to cilia disassembly.
095
Reposted by Elias Spiliotis
Triangle Cytoskeleton Meeting @tricytomeet.bsky.social · 27/07/2026
All registration deadlines are listed below. Stay tuned for more posts about our other invited speaker, Dr. Matthew Tyska, and our Keynote speaker, Dr. James Sellers! We are excited to see you at this year's meeting! Please reach out to tcdrm.info@gmail.com with any questions. (3/3)
011
Reposted by Elias Spiliotis
Triangle Cytoskeleton Meeting @tricytomeet.bsky.social · 27/07/2026
SEPT9 is a septin amplified in breast cancer. The Spiliotis lab combines live imaging of confined migrating cells, Clinicogenomic data, and more to tease apart SEPT9's mechanoprotective role. Register to hear more about this exciting research at this year's TCM: forms.gle/QGELSmPhAMGK... (2/3)
forms.gle
2026 Triangle Cytoskeleton Registration
Thank you for your interest in the 2026 Triangle Cytoskeleton Meeting! Please fill out the information in the form below. To finish registration and pay for attendance please go to: ...
142
Elias Spiliotis @septinlab.bsky.social · 28/07/2026
Looking foreword to visit and present in North Carolina! And grateful for the invitation 🙏
011
Elias Spiliotis @septinlab.bsky.social · 26/07/2026
I just discovered my 140 record reviews as a dj at Stanford's KZSU (ca 2002-2008) If I never get to that number of publications, please throw me a retirement as a "music writer"... zookeeper.stanford.edu:8443?action=viewR...
zookeeper.stanford.edu
020
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 25/07/2026
www.sciencedirect.com/science/arti... The actin crosslinker Fimbrin is required for force sensing at tricellular junctions
0136
Reposted by Elias Spiliotis
EMBO Reports @emboreports.org · 24/07/2026
The second July issue is online: link.springer.com/journal/4431... The cover features work by Naoyuki Inagaki, Kio Yagami and colleagues from NAIST describing spontaneous membrane protrusion and cell morphogenesis via self-propelled #actin filaments. -> link.springer.com/article/10.1...
054
Reposted by Elias Spiliotis
Ana Coelho Almeida @ac-almeida.bsky.social · 22/07/2026
Hot off the press!! 🚨 Our work is now published in #NatureCommunications! We show that keeping tubulin levels in check is key for preserving microtubule dynamics, multicellular architecture and viability. A huge thank you to the @ivanagasic.bsky.social team for making this possible! 🙌 rdcu.be/fu8ek
rdcu.be
Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Nature Communications - Almeida AC et al. uncover the physiological role of a long-elusive feedback pathway that regulates tubulin biosynthesis. By tuning microtubule dynamics, this mechanism...
073
Elias Spiliotis @septinlab.bsky.social · 24/07/2026
Thank you for your service www.nytimes.com/2026/07/23/u...
nytimes.com
Number of U.S. Troop Deaths in Iran War Appears Lower on Pentagon Website
Three military officials and a Pentagon spokesman gave conflicting explanations for why the number of Americans killed in the Iran war had changed.
001
Reposted by Elias Spiliotis
Josh Busby @busbyj2.bsky.social · 24/07/2026
Who needs joy? www.youtube.com/watch?v=PNmc...
youtube.com
David Byrne: Tiny Desk Concert
YouTube video by NPR Music
2458
Reposted by Elias Spiliotis
The New York Times @nytimes.com · 21/07/2026
This Turkish yogurt cake is similar to a lemon-scented cheesecake, but it’s lighter and has a fresher, tangier flavor. nyti.ms/4fcwnZf
nyti.ms
Yogurt Cake Recipe • 4★
This Turkish yogurt cake, adapted from the cookbook “Claudia Roden’s Mediterranean,” is similar to a lemon-scented cheesecake, but it’s lighter and has a fresher, tangier flavor. It’s good both warm and cold, either on its own or topped with berries that have been macerated in a pinch or two of sugar.
6627
Elias Spiliotis @septinlab.bsky.social · 18/07/2026
If you type "Journal of Cell Biology" in google search box and hit enter... this is the result:
110
Elias Spiliotis @septinlab.bsky.social · 17/07/2026
O' clathrin vesicle, where art thou? And COPI and COPII...?
030
Elias Spiliotis @septinlab.bsky.social · 15/07/2026
Wild. And pretty awesome!
140
Elias Spiliotis @septinlab.bsky.social · 15/07/2026
From Beastie Boy Mike D's upcoming solo album... first music in 15 years Welcome back Mike D - hope for new with Adam next www.youtube.com/watch?v=ssKf...
youtube.com
Mike D - True Colors (Visualizer)
YouTube video by MikeDMusicVEVO
020
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 10/07/2026
Inorganic phosphate rapidly switches the stability of Arp2/3-induced actin branches rupress.org/jcb/article/...
083
Reposted by Elias Spiliotis
Nogales Lab @nogaleslab.bsky.social · 10/07/2026
🧵 New paper alert! Today on bioRxiv, we show how a microtubule (MT) associated protein, MTCL1, links 2 regulatory layers: mechanical MT stabilization and writing of then tubulin code. A multi-lab effort driven by Juan Perez-Bertoldi and Julie Dang spanning atoms to organisms. 1/n
1289
Elias Spiliotis @septinlab.bsky.social · 10/07/2026
I caught this great interview with legendary guitarist Lenny Kaye while driving yesterday. Brilliant quote by Patti Smith: "Progress isn't the future, it's keeping up with the present." www.npr.org/2026/07/09/n...
npr.org
'Music belongs to the moment': Patti Smith's guitarist Lenny Kaye is 'Goin' Local'
Kaye's collaboration with Smith began in 1971 and continues to this day. He says she taught him to trust his musical sensibilities — and to always keep evolving. Now 79, he has his first solo album.
010
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 08/07/2026
www.biorxiv.org/content/10.6... Unbranched SPIN90-Arp2/3 actin promotes stress fiber speed and focal adhesion maturation
053
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 07/07/2026
www.biorxiv.org/content/10.1... Multiple evolutionary routes to cytoskeletal arborization revealed by the rhizarian amoeba Filoreta ramosa
0124
Reposted by Elias Spiliotis
Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 04/07/2026
Quebec defeats United States — look at that CROWD!
youtube.com
Angine de Poitrine - Yor Zarad - Montreal International Jazz Festival - June 27, 2026
YouTube video by Sopmylo
043
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 02/07/2026
www.molbiolcell.org/doi/10.1091/...
molbiolcell.org
Non-muscle Myosin II acts as a negative feedback mediator to control cell contraction dynamics in adherent cells | Molecular Biology of the Cell
Pulsatile cell contraction dynamics play a crucial role in tissue and cell morphogenesis. Previously, we identified a signal network in adherent mammalian cells, that can transduce mechanical signals ...
032
Reposted by Elias Spiliotis
Abby Buchwalter @abbybuch.bsky.social · 01/07/2026
Hey #nucleus nerds, the JCS Special Issue on the Cell Biology of the Nucleus is now live! This was a pleasure to co-edit with Megan King @luskinglab.bsky.social.
24818
Reposted by Elias Spiliotis
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 02/07/2026
Synergistic assembly, disassembly, and protection of complex forms of bundled F-actin rupress.org/jcb/article/...
022
Elias Spiliotis @septinlab.bsky.social · 02/07/2026
"...rejected by Cell after one reviewer said SpudCells were not real biology... then sent the 190-page manuscript to journalists, under embargo, even before uploaded it to bioRxiv... She says her group will submit it to a new journal soon." www.science.org/content/arti...
science.org
Lab-created ‘SpudCell’ marks ‘stunning’ step toward building life from scratch
A synthetic cell can now grow and divide—but it’s still far from alive
000
Reposted by Elias Spiliotis
Danielle Grotjahn @nanigrotjahn.bsky.social · 29/06/2026
New Grotjahn lab preprint from superstar postdoc @nitishdua.bsky.social! Check out all the deets in the 🧵 below. IMO, it’s a great example of how studying the local microenvironment with #teamtomo can reveal biology that would otherwise remain hidden. #mitochondria #morphometrics
0213
Elias Spiliotis @septinlab.bsky.social · 27/06/2026
Air Hill, and priceless and rare ear-to-ear Wheeler smile! #SeasonHighlight
000
Reposted by Elias Spiliotis
Nikon Microscope Solutions @healthcare.nikon.com · 23/06/2026
🗣️ A milestone year is ending, but the legacy continues. 🎥 From antique models to unique optical instruments, a passionate collector of Nikon microscopes, Uli Koch’s collection showcases the beauty and history behind how we observe the microscopic world. 👉Read more: bit.ly/479zk9j
021
Reposted by Elias Spiliotis
Kaitlin McCreery @mccreery.bsky.social · 12/03/2025
Our review "Measuring and manipulating mechanical forces during development" is now published in Nature Cell Biology! #Mechanobiology #DevelopmentalBiology
0176
Reposted by Elias Spiliotis
Jan Lammerding - Lab @lammerdinglab.bsky.social · 12/05/2025
How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and what role does #mechanobiology play here? Learn more in our recent review by fantastic Sarah Henretta, now out in NPJ - Biological Physics and Mechanics, open access: doi.org/10.1038/s443...
doi.org
Nuclear envelope proteins, mechanotransduction, and their contribution to breast cancer progression - npj Biological Physics and Mechanics
npj Biological Physics and Mechanics - Nuclear envelope proteins, mechanotransduction, and their contribution to breast cancer progression
05214