In a key clinical trial, patients who got the pill, daraxonrasib, lived twice as long as those who got chemotherapy.

At least a half-dozen federal agencies have taken action against the state that has long led the nation in environmental protections.

Kuzuoglu-Ozturk et al. showcase a therapeutic approach, “translatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1α through remodeling their 5′ UTR RNA structure. Zotatifin enhances anti-androgen and radiotherapy sensitivity, highlighting a promising anti-cancer treatment.

The agency announced it is repealing its 2009 conclusion that greenhouse gases warm the Earth and endanger human health and well-being.

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KRAS mutations, which induce proliferative signaling driving many human cancers, are detectable in a small subset of osteosarcoma patients. The recently developed pan-KRAS inhibitor daraxonrasib, also...

There are a lot more fast chargers than there used to be. Look up what that could mean for a route near you.

In the final analysis of a phase 1 trial evaluating a lymph node-targeting mutant KRAS peptide vaccine combined with CpG in the adjuvant setting for patients with KRAS mutant pancreatic or colorectal ...

25 Colleges. One University.

RAS is the most frequently mutated oncogene in cancer. RAS proteins show high sequence similarities in their G-domains but are significantly differ...

Ongoing trials will reveal whether suzetrigine is also effective against chronic pain

Recent studies provide new insights into signaling by mutant KRAS, inhibitors of which have provided modest benefits for patients.

Open-rank tenure/tenure-track faculty search for biochemist focused on cancer biology or cancer-relevant signaling pathways in model organisms.