iiinova — where your digital self keeps evolving

Reposted by Falk Schneider

bioRxiv Biophysics @biorxiv-biophys.bsky.social · 09/10/2026

mCranberry: A rationally engineered monomeric red fluorescent protein with 85% quantum yield www.biorxiv.org/content/10.64898/20…

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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 06/10/2026

🏁 That's a wrap! The @biohub.org Cell Tracking machine learning challenge on @kaggle.com is over: 4,478 participants, 3,947 teams, 120 countries, 95,438 submissions, tracking every cell of zebrafish embryos. 🧪🔬🧵 kaggle.com/competition... #microscopy

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Heilemann Lab @heilemannlab.bsky.social · 25/09/2026

#FluorescenceFriday #STED pure and real 8-color STED microscopy & happy TxIF to everyone 🌴

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Diz-Muñoz Lab @diz-lab.bsky.social · 03/10/2026

We built a fully functional LegoAFM for imaging! 🤩... Today presented at #TürenAuf Tag der #SendungMitDerMaus! ... Remember: Always be curious! ⁉️

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Falk Schneider @faldalf.bsky.social · 02/10/2026

How did I miss this? Serious membrane organisation story by my colleagues at @mechanochemistry.org @uni-of-warwick.bsky.social Lipids, actin, myosin, GPI-APs, and homo-FRET - what is there not to like?

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Reposted by Falk Schneider

Mathilda Lennartz @mathilda95.bsky.social · 30/09/2026

UPDATE!: I am absolutely stoked that the second paper of my PhD is now out in @natcellbio.nature.com :D. We combined lipid imaging, STED microscopy, and mathematical modelling in a super cool team effort to quantify lipid partitioning inside clathrin-coated pits. www.nature.com/articles/s41....

nature.com

Quantification of lipid sorting during clathrin-mediated endocytosis - Nature Cell Biology

Lennartz et al. evaluate lipid enrichment in clathrin-coated pits and observe that the differential lipid partitioning into clathrin-coated pits is largely driven by the lipid asymmetry of the plasma ...

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Reposted by Falk Schneider

Tessa Montague @tessamontague.bsky.social · 29/09/2026

I'm excited to share our new preprint: Generation of a transgenic cephalopod tinyurl.com/pc86jxz8 Cephalopods (cuttlefish, octopus & squid) are crazy critters that dynamically camouflage to their surroundings by changing the color, pattern, & texture of their skin, which they control w their brain.

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napari @napari.fosstodon.org.ap.brid.gy · 26/09/2026

🚀 napari is hiring Remote Developers-in-Residence! Join us to build the future of interactive n-dimensional data visualization in Python. 💻 60% Dev / 20% Maintenance / 20% Community & Outreach 💰 $59.50/hr (Contract, 14–35 hrs/wk) 🌍 100% Remote, open globally Learn more and apply today […]

fosstodon.org

Original post on fosstodon.org

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Reposted by Falk Schneider

Valentin Dunsing-Eichenauer @dunsingvalentin.bsky.social · 25/09/2026

#FluorescenceFriday: Given the recently grown interest in ciliary beating, here is a movie of beating cilia in a human airway model that I captured last week with lattice light-sheet microscopy. No AI „processing“, this is the raw data! Frame rate is ca. 170fps, displayed here at 25fps.

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Jonas Wietek @jwietek.bsky.social · 24/09/2026

Two cillia, no AI, enjoy.

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Giovanni D’Angelo @giodang.bsky.social · 23/09/2026

#lipidtime: It's a lipid universe. Today in Nature we publish the Lipid Brain Atlas, the first map of membrane lipid composition across the entire mouse brain, a layer of organisation that cell-type and transcript maps had left out. #lipidomics #neuroscience #BrainAtlas

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André Nadler @nadlerlab.bsky.social · 23/09/2026

This my friends, this is the big one. A long time coming. Lipid Cell Biology is coming of age and even for a hot field, this is a true game changer. This dataset will keep us all busy for years to come. Congrats to everybody on this amazing crew!!! Go party!!

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Reposted by Falk Schneider

Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

1/23 I have fantastic news! I am truly honored to have been awarded an Emmy Noether-Grant by @dfg.de @uni-muenster.de Since most of you are not from Germany, I will use the following posts to explain what this Program is, who Emmy Noether was and what my group in Münster will be doing. #cellbio

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Charles West @pseudo-isidore.bsky.social · 19/09/2026

21,627 applications for the Marie Curie early career fellowships.

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Steffen Scholpp @scholpplab.bsky.social · 17/09/2026

How does a Wnt cytoneme contact become a productive signalling site? Emma Cooper and colleagues find focal Ca²⁺ transients at cytoneme contacts and link Ca²⁺ availability to contact stability and Wnt/β-catenin signalling. www.biorxiv.org/content/10.6... #Wnt #Cytonemes #CellBiology

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Reposted by Falk Schneider

adafruit @adafruit.com · 17/09/2026

Build an MP3 audio player with #CircuitPython and parts from #Adafruit ! This personal music player features a tft display and mechanical key switches. Learn guide: learn.adafruit.com/walkmp3rson-... youtu.be/fgalBx2QSJ0 #3DPrinting

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Sergey Ovchinnikov @sokrypton.org · 14/09/2026

Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr)

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BWJones @bwjones.bsky.social · 09/09/2026

Has anyone seen their STED microscopes do this to tissues? This is on the lowest power setting... What's up?

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bedzhov lab @bedzhovlab.bsky.social · 08/09/2026

2x Group leader/Professor positions at Uni Salzburg in: Developmental biology: www.plus.ac.at/personalwese... Endocrinology: www.plus.ac.at/personalwese...

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Reposted by Falk Schneider

Joachim Goedhart @joachimgoedhart.bsky.social · 08/09/2026

PURELIGHT: a quantitative photon-counting framework unifying intensity and lifetime imaging at video rate across detector technologies by Luca Ravotto and team: www.biorxiv.org/content/10.6...

High-speed FLIM imaging of astrocytic calcium dynamics with Tq-Ca-FLITS

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Reposted by Falk Schneider

Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 04/09/2026

A nice study by @laboptbio.bsky.social colleagues V.Abdelsayed, P.Mahou,G.Latour,MC.Schanne-Klein and collaborators in J.Ramella-Roman's group at FIU. They use polarized SHG to analyze the reorganization of cervix collagen matric during gestation in mice. Congrats Vaky & co! doi.org/10.1063/5.03...

doi.org

Advanced optical polarimetric microscopy reveals spatio-temporal dynamics of cervix remodeling during gestation

Polarimetric microscopy is a powerful tool for assessing fiber orientation and reorganization during various biological processes. Collagen fiber remodeling in

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Reposted by Falk Schneider

Journal of Cell Biology @jcb.org · 07/09/2026

The cell biologist’s guide to detecting and modulating membrane #phospholipids. A review by Worcester, @gerryhammond.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Christoph Dellago @chhdellago.bsky.social · 07/09/2026

If you are like me, you start every morning by making yourself a coffee with a moka pot. ☕️ While you wait for the coffee to bubble up, you can now explore how it works: compphys.univie.ac.at/Moka I made this (thank you, Claude!) for my thermo and stat phys course, but perhaps you enjoy it too.

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Coskun Lipid Cellar @ ZML Dresden @lipid.bsky.social · 15/12/2025

Ups we did it again! Please mark your calender. EMBO Workshop “Lipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova, @lipid.bsky.social, Valerie O'Donnell, @holthuislab.bsky.social and @molcellbiophys-lab.bsky.social 🥳 Retweets = lipidlove

copyright Palina Nepachalovich of ZML Dresden

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Reposted by Falk Schneider

Pol Solé Navais @polsolenavais.bsky.social · 05/09/2026

📣📣📣 The University of Gothenburg (Sweden) is recruiting 25 (yes, 25!) Assistant Professors in a wide range of disciplines (from arts to education to geology to maths), two of these at our Faculty. Happy to talk to anyone interested in knowing more about Sweden, Gothenburg or GU!

gu.se

Gothenburg Global Scholars Initiative

The University of Gothenburg is launching the Global Scholars Initiative – a coordinated international recruitment effort comprising 25 research positions across a broad range of disciplines and facul...

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Reposted by Falk Schneider

Stephen Royle @steveroyle.bsky.social · 04/09/2026

NEWS: @anne.mechanochemistry.org and I are the new Joint Directors of the Centre for Mechanochemical Cell Biology (CMCB) at Warwick @mechanochemistry.org We thank @rob.mechanochemistry.org who has been at the helm of CMCB since its inception. Looking forward to more exciting science in the future.

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Reposted by Falk Schneider

Development @dev-journal.bsky.social · 04/09/2026

The role of geometry in morphogenesis Read this Review from our special issue #DevSIextracellular by Ryan Harrison, Olivier Hamant and @timesaunders.bsky.social. journals.biologists.com/dev/article/...

Role of geometry in shaping tissues. Multiple factors, including cell shape (top left), boundary constraints (top right), topological inputs (bottom left) including from different cell alignment defects (±1/2) and biophysical factors (bottom right) impact how the final tissue form emerges (centre). Centre shows images of a 48 h neuruloid (left; magenta, DAPI; green, actin) and a young Arabidopsis flower (right) treated with oryzalin (depolymerised microtubules) thus showing isotropic growth, but no defect in patterning (organs are still initiated in the right position).

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Reposted by Falk Schneider

Wilbert Bitter @wilbertbitter.bsky.social · 02/09/2026

Please have a look at our review on a very interesting and underappreciated group of proteins... Getting a grip on StAR-related lipid-transfer (START) domain proteins in bacteria academic.oup.com/femsre/artic...

academic.oup.com

Getting a grip on StAR-related lipid-transfer (START) domain proteins in bacteria

Bacterial START domain proteins have a conserved helix-grip fold, but diverge from mammalian lipid transporters by utilizing a more versatile array of proc

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Chad Hobson @cmhobson.bsky.social · 27/08/2026

A couple years in the making, but the preprint is finally out! We developed a pipeline for timelapse, volumetric FLIM (vFLIM) that incorporates multi-channel light sheet excitation, a SPAD array detector for widefield FLIM, and machine learning lifetime processing. www.biorxiv.org/content/10.6...

biorxiv.org

vFLIM: Machine Learning-enabled Light Sheet Fluorescence Lifetime Imaging

The lifetime of fluorescent molecules provides an orthogonal readout to fluorescence intensity, opening experimental possibilities of measuring changes in local molecular environments, mechanical tens...

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Reposted by Falk Schneider

Reese Richardson @reeserichardson.bsky.social · 25/08/2026

A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵

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MwahahahahahadScientist @mads100tist.bsky.social · 29/08/2026

Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)

biorxiv.org

FOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopy

Understanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar...

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hernanggarcia.bsky.social @hernanggarcia.bsky.social · 20/08/2026

MS2 in zebrafish @cp-cellsystems.bsky.social! Eck, Moretti and Schlomann, in collaboration with our friends in the of @loicaroyer.bsky.social and Oates labs, discovered that smooth protein oscillations in the segmentation clock are the result of transcriptional pulses: tinyurl.com/hwbf525m

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Kate Cavanaugh @katecavanaugh.bsky.social · 25/08/2026

🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical? Thrilled to share our new paper in @NatureCellBio : Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇 www.nature.com/articles/s41... 1/11

nature.com

Elevated contractility drives implantation failure in mouse embryos from aged females - Nature Cell Biology

Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...

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Erik van Nimwegen @erikvannimwegen.bsky.social · 21/08/2026

What if I run Bonsai on random data? Will it tell me the data have no structure? Yes, it does. Random points in a high-dimensional space are all equi-distant and, in contrast to other visualization methods, Bonsai will tell you all cells are equi-distant. 5/n

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Robert Arkowitz @robertarkowitz.bsky.social · 20/08/2026

ImpRes: A robust FRAP framework to quantify fast diffusion of cytoplasmic probes Olivier Destrian, Rene-Marc Mege, Benoit Goyeau, Morgan Chabanon bioRxiv 2026.08.14.744877; doi: doi.org/10.64898/202... www.biorxiv.org/content/10.6...

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Falk Schneider @faldalf.bsky.social · 29/07/2026

😱🤩 wow! Shining light on lipid-protein interactions #lipidtime Monumental work and awesome skytorial @nadlerlab.bsky.social Very excited to dig through the preprint. Congratulations already 🎉

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Jonas Ries @jonasries.bsky.social · 28/07/2026

Long time in the making and finally out. Great work by Lucas and @haosha.bsky.social who wrote the code, Maxime and Nestor for the beautiful samples and @zacsimile.bsky.social for helping to wrap this up. Try it out!

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Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 26/07/2026

The first 22 hours of #zebrafish development in under one minute. Credit to @zebrafish007.bsky.social in #WeinsteinLab at NIH. #ZebrafishZunday 🧪

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Reposted by Falk Schneider

Will Scott @wsctt.bsky.social · 24/07/2026

Recently we were trying to change the colour of superfolder GFP and accidentally engineered a great probe for expansion microscopy! Read about it in our first micropublication - lnkd.in/eCxYcCJZ

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CMU Mellon College of Science @cmuscience.bsky.social · 23/07/2026

CMU biophysicists are flipping the script on cell membrane dynamics. They’ve developed a new theoretical framework that links membrane stress to lipid flip-flop, uncovering a key driver of membrane asymmetry. 🧪⚛️ www.cmu.edu/mcs/news-eve...

cmu.edu

CMU Researchers Capture the Randomness of Lipid Flip-Flopping

Cell membranes are dynamic, two-sided structures made of asymmetric lipid layers. While lipids can randomly flip-flop from one layer to the other, membrane proteins sort lipids between the two sides. ...

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FreeCAD @freecad.org · 23/07/2026

FreeCAD 1.1.2 is out. Bugfix release only, no new features, but 32% of the patches fix BIM and core issues, and 12% are security fixes. Recommended update for everyone! blog.freecad.org/2026/07/23/freecad-1-1-2-released/ Support the project: wiki.freecad.org/Donate #FreeCAD #CAD #OpenSource

blog.freecad.org

FreeCAD 1.1.2 released

We are pleased to announce the release of version 1.1.2. This release pulls important fixes from the current development branch without adding any new features. 32% of the backported patches fix is…

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Falk Schneider @faldalf.bsky.social · 23/07/2026

@wsctt.bsky.social and Nimo Abdullah from @sporemohan.bsky.social lab demonstrate the potential of 3-iodotyrosine containing FPs for expansion microscopy 🔬🐟🌈 Happy to have played a small role in this exciting project Findings available @micropub7n.bsky.social micropublication.org/journals/bio...

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MOHAN BALASUBRAMANIAN @sporemohan.bsky.social · 21/07/2026

Here is our one figure paper in micropublications. A new tool for protein expansion microscopy. First time in @micropub7n.bsky.social and loved the experience Please let me know if you have some feedback and how this may be incorporated into other work micropublication.org/journals/bio...

micropublication.org

3-iodotyrosine fluorescent proteins for improved expansion microscopy | microPublication

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