During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.

OverviewIn 2009, the Institut Pasteur, the world leading biomedical research institute founded by Louis Pasteur in 1887, inaugurated the Pasteur Paris-University (PPU) international doctoral program i...

Deadenylation leads to mRNA decay, with PABPC1 protecting the poly(A) tail, while tristetraprolin and CCR4–NOT promote deadenylation. Here, the authors describe how these three proteins interact to re...

An agent-based large language model (LLM) tool helps with CRISPR-based gene-editing experimental design and analysis.

A step-by-step Cryo-ET guide

A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms

The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA Wor…

Abstract. The 22q11.2 deletion syndrome (22qDS) is a human disorder where the majority of clinical manifestations originate during embryonic development. 2

The preLights conference reporter for Biologists @100, Jonathan Townson, is collating a preList that aims to capture all preprints being discussed at the meeting (either as part of the poster sessions...

Abstract. Across cell types and organisms, thousands of RNAs display asymmetric subcellular distributions. Studying this process requires quantifying abund

This grant program funds the recruitment of predoctoral research staff in training to carry out a doctoral thesis in the fields covered by the Strategic Technologies for Europe Platform (STEP), you ca...

A team from the Center for Genomic Regulation in Barcelona details the molecular mechanism of a rare illness that causes transient paralysis and dangerous arrhythmias

The Company of Biologists is looking for one or more interns, through the BBSRC DTP/PIPS or equivalent schemes, to work on our community sites – the Node,

RNA plays a central role in protein biosynthesis and performs diverse regulatory and catalytic functions, making it essential for all processes of life. Like DNA, RNA is constantly subjected to damage...

Sood et al. used high-throughput screening to identify regulators of gene bursting and find both gene- and cell-type-specific effectors. Acetylation alters burst size in a gene-specific manner but is independent of promoter acetylation. Rather,…

The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.

Ribosomes cooperate through transient collisions to ensure efficient translation.

Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...

imageimagec-di-GMP binds to and inhibits the rRNA methyltransferase RlmI and modulates ribosome assembly under antibiotic stress. The data suggest an unexpected mechanism by which c-di-GMP might promo...

Thank you for your interest in our seminar series! We use a variety of different session formats but, in general, trainees can plan for a ~15 min talk + 5min Q/A and PIs can plan for a ~25min talk +...