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Mireya Plass

@mireyaplass.bsky.social
496 followers 708 following 60 posts

Associate professor at Universitat de Barcelona. Studying post transcriptional regulation in single cells and Alzheimer's Disease. iPSCs, gene regulatory networks, bioinformatics, systems biology www.plasslab.com

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Reposted by Mireya Plass
Saez-Rodriguez Group @saezlab.bsky.social · 07/09/2026
🧵 Introducing Karenina, an open-source framework to evaluate LLMs & agents: doi.org/10.64898/202...
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Mireya Plass @mireyaplass.bsky.social · 27/08/2026
🚨 Job Alert We are looking for a Research Technician to join my lab a IDIBELL/UB The successful candidate will support experimental work in the lab. Tasks include the culture and differentiation of iPSC cell lines, characterization 2D human nervous system models
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Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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Alejandro Barrallo @abarrallo.bsky.social · 15/06/2026
Against all odds, me & @mireyaplass.bsky.social got funded by @idibell.bsky.social to perform some scRNAseq on zebrafish hair cells!
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Mireya Plass @mireyaplass.bsky.social · 06/05/2026
If you want to do a master in biomedicine or similar @ub.edu and a research stay at my lab to study early alterations in AD contact me!
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Ming Tommy Tang @tommytang.bsky.social · 06/05/2026
7 FREE Books to learn data science 🧵 👇 1. Data science: A first introduction datasciencebook.ca/
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Michael Love @mikelove.bsky.social · 03/05/2026
A new package, splicelogic, in Bioc 3.23 from lab member Bea Campillo @beamimc.bsky.social splicelogic allows users to find alternative splicing events after performing differential transcript usage (DTU) analysis. We're eager to have folks try this one out! thelovelab.github.io/splicelogic/
Screen shot of the quick start instructions. Prepare exons, preprocess, then find splicing events. See the github page for the rest of the quick start code and installation instructions.
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Guillermo Peris 🧬💻 @waltzingpiglet.bsky.social · 10/04/2026
El próximo 27 de abril celebraremos las I Jornadas andaluzas sobre el Síndrome 22q11.2, un encuentro entre investigadores, médicos y pacientes, con enfoque multidisciplinar e integrador entre profesionales y familias. ¡Únete!
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Facultat de Medicina i Ciències de la Salut @medicinacs-ub.bsky.social · 10/04/2026
#RecercaUB | L’estudi, dut a terme amb models animals i publicat a la revista @cellpress.bsky.social , el lideren els investigadors Òscar Molina i Pablo Menéndez, de la facultat i de @carrerasijc.bsky.social. La IP és Namitha Thampi, membre d'ambdues institucions. 🔬 bit.ly/4c1graD #leucèmia
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Ana Gázquez-Gutiérrez @anagazquezg.bsky.social · 05/03/2026
I'm so happy to share our latest paper! Now out in @narjournal.bsky.social 🥳 Did you know that transposable elements embedded in mRNAs can form dsRNA and activate innate immunity? 🧬🦠 Have a look! academic.oup.com/nar/article/... #TEsky #RNAsky #RNAbiology #immunity #NAR
academic.oup.com
Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8
Abstract. The type I interferon (IFN) response is the main innate immune pathway against viruses in mammals. This pathway must be tightly regulated to prev
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Torben Heick Jensen @heick.bsky.social · 06/03/2026
Postdoc positions available in my lab in Aarhus, Denmark on 'Mammalian Nuclear RNA Production and Turnover Systems'. Please get in touch for further information or simply apply here: mbg.au.dk/en/news-and-...
mbg.au.dk
Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University
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Reposted by Mireya Plass
Nature @nature.com · 06/03/2026
An assessment of sensitivity to increasing temperature for thousands of insect species reveals a risk of insect biodiversity loss go.nature.com/4leGXQO
go.nature.com
Rising temperatures pose a threat to tropical insects
An assessment of sensitivity to increasing temperature for thousands of insect species in mountainous terrain reveals a risk of insect biodiversity loss in tropical lowlands.
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bioRxiv Genomics @biorxiv-genomic.bsky.social · 20/02/2026
Pan-cell-type prediction of splicing patterns from sequence and splicing factor expression www.biorxiv.org/content/10.64898/20…
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Reposted by Mireya Plass
Carmelo Ferrai @carmeloferrai.bsky.social · 14/02/2026
Tread -1- EpiSci - I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below) "The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A. www.biorxiv.org/content/10.6...
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Fabian Theis @fabiantheis.bsky.social · 05/02/2026
CellRank protocol now in @NatureProtocols! 🎉 @PhilippWeiler's detailed guide shows how to: - Integrate velocity, pseudotime & time points - Infer cell fate probabilities - Analyze lineage priming at scale Great complement to our CellRank 2 paper! 📖 www.nature.com/articles/s41...
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CNAG @cnag-eu.bsky.social · 05/02/2026
⏳¡Cuenta atrás para el evento 'El Proyecto Genoma Humano, 25 años después'! El investigador @rodericguigo.bsky.social (@crg.eu), que formó parte de este gran hito biomédico, nos contará por qué supuso un antes y un después en la biología ¡No os lo perdáis!👇 🔗 www.cnag.eu/events/el-pr...
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Agencia Estatal de Investigación @ageinves.bsky.social · 05/02/2026
🆕Nueva guía recopilatoria de obligaciones de comunicación y publicidad de las ayudas concedidas (2026). www.aei.gob.es/ayudas-conce... 🔧Es una herramienta esencial para ayudar a los beneficiarios de las subvenciones a identificar cómo deben dar publicidad a las ayudas recibidas.
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Gallego Lab @gallegolab.bsky.social · 26/01/2026
Please share🙏: Our lab opens 2 PhD positions to investigate fungi's evolution: #Barcelona Wet lab in Biochemistry/Structural Biology of cryo-tolerant fungi www.upf.edu/documents/d/... Computational in Physical Chemistry of cellular processes under extrem environments www.upf.edu/documents/d/...
upf.edu
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Mireya Plass @mireyaplass.bsky.social · 22/12/2025
Great work showing the power of scATAC-seq to decode ontogenetic relationships! Maybe I will check chromatin after all...
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Xavier Grau-Bové 🌾 @xgrau.bsky.social · 22/12/2025
From a personal POV, tagging along with @martaig.bsky.social and @aelek.bsky.social while they developed this project has been one big learning opportunity. In Nematostella biology, clever omics, evo-devo, and more. And the paper certainly reflects all of that. Go check it out!
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Arnau Sebé-Pedrós @arnausebe.bsky.social · 22/12/2025
Excited to share the final version of our study on Nematostella cell type regulatory programs. Part of our @erc.europa.eu StG project, this was a challenging 5-year effort extraodinarily led by @aelek.bsky.social and @martaig.bsky.social. www.nature.com/articles/s41...
nature.com
Decoding cnidarian cell type gene regulation - Nature Ecology & Evolution
This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evoluti...
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martaig.bsky.social @martaig.bsky.social · 22/12/2025
Lovely Xmas gift 🎄—our paper is out today in @natecoevo.nature.com www.nature.com/articles/s41...! Huge thanks to everyone who made it possible, especially @aelek.bsky.social and @arnausebe.bsky.social
nature.com
Decoding cnidarian cell type gene regulation - Nature Ecology & Evolution
This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evoluti...
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Mireya Plass @mireyaplass.bsky.social · 22/12/2025
Great work showing the power of scATAC-seq to decode ontogenetic relationships! Maybe I will check chromatin after all...
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Mireya Plass @mireyaplass.bsky.social · 19/12/2025
Awesome talk from @akshayjg.bsky.social at the Jornades de Bioinformàtica i Genòmica presenying our work on Alzheimer's disease using iPSCs and scRNAseq.
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Kerstin Göpfrich @kgoepfrich.bsky.social · 09/12/2025
We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
nature.com
Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668
The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...
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Esteban Hoijman @estebanhoijman.bsky.social · 09/12/2025
Want to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com
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PCI Genomics @genomics.peercommunityin.org · 01/12/2025
"Bulk RNA-seq to the rescue of differential expression analysis in single-cell transcriptomics" 🧫 📑 A new PCI Genomics recommendation by @mireyaplass.bsky.social: doi.org/10.24072/pci...
doi.org
Bulk RNA-seq to the rescue of differential expression analysis i...
Due to the costs of single-cell sequencing, sample sizes are often relatively limited, sometimes leading to poorly reproducible results. In many contexts, however, larger bulk RNAseq data is…
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Mireya Plass @mireyaplass.bsky.social · 03/11/2025
🚨Interested in studing RNA regulation & neurodegeneration in single-cells? Join my lab @ub.edu in Barcelona! We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
aei.gob.es
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Caleb M. Gordon @caleb-m-gordon.bsky.social · 20/11/2025
Hey everyone! I’m excited to share that one of my thesis projects was just published in @currentbiology.bsky.social and featured on phys.org! In this paper, we use an old statistical approach developed by the US Navy in WW2 to predict the aquatic habits of various dinosaurs and marine reptiles 🦖🐊
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Fundación Pasqual Maragall @fpmaragall.bsky.social · 21/11/2025
¡Ya llevamos 212.352€ recaudados! Estamos más cerca que nunca de lograr crear el algoritmo capaz de anticiparse al Alzheimer. Ayúdanos a seguir investigando 🧠🔬. Dona ahora en anticiparsealalzheimer.org
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Reposted by Mireya Plass
bioRxiv Genomics @biorxiv-genomic.bsky.social · 10/11/2025
Integrated analysis of multimodal long-read epigenetic assays www.biorxiv.org/content/10.1101/202…
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Mireya Plass @mireyaplass.bsky.social · 03/11/2025
🚨Interested in studing RNA regulation & neurodegeneration in single-cells? Join my lab @ub.edu in Barcelona! We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
aei.gob.es
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Champi @jpascualanaya.bsky.social · 30/10/2025
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch! 📅 Starting date early 2026, with some flexibility. 🙏Please, RT!
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Mireya Plass @mireyaplass.bsky.social · 30/10/2025
Finally after 5 years the first PhD from the lab! Congratulations Dr. Ake @franzake.bsky.social !!! 👏👏👏 🎉🎉🎉 It has been a pleasure to have you in the lab. #PhD_defense #new_PhD
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Akshay Ganesh @akshayjg.bsky.social · 03/10/2025
Excited and grateful to be part of this work with @smfernandezmoya.bsky.social and @mireyaplass.bsky.social at the Gene Regulation of Cell Identity lab!
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Mireya Plass @mireyaplass.bsky.social · 02/10/2025
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells www.biorxiv.org/content/10.1...
biorxiv.org
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
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Mireya Plass @mireyaplass.bsky.social · 03/10/2025
This project would have been impossible without the work of our collaborators Agnieskza Rybak-Wolf, @monikapiwecka.bsky.social & Alessandra Gioregtti.
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Mireya Plass @mireyaplass.bsky.social · 02/10/2025
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells www.biorxiv.org/content/10.1...
biorxiv.org
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
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Mireya Plass @mireyaplass.bsky.social · 03/09/2025
#SENC2025 has just started. Looking forward to these 3 days showing the best neuroscience research in Spain.
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Manuel Irimia @mirimiam.bsky.social · 07/08/2025
Very happy to share the peer-reviewed version of our work on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4, published in @natsmb.nature.com! rdcu.be/ezGqT Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
rdcu.be
Core splicing architecture and early spliceosomal recognition determine microexon sensitivity to SRRM3/4
Nature Structural & Molecular Biology - Using massively parallel splicing assays and mathematical modeling, Bonnal et al. uncover that conserved splice site strength and exon length encode...
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Manuel Irimia @mirimiam.bsky.social · 06/08/2025
🧬🧬🧬 New review from the lab: Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks authors.elsevier.com/sd/article/S... By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.
Three major trends in comparative transcriptomics
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Human Technopole @humantechnopole.bsky.social · 29/07/2025
🎓 Just graduated and passionate about Computational #Biology, Structural Biology, #Genomics or #Neurogenomics? Apply by 8 Sept for 1 of 9 fully funded PhD scholarships via the SEMM Program at HT in Milan! 👉 humantechnopole.it/en/news/call... #PhDlife
humantechnopole.it
Call for Applications: Fully Funded PhD Scholarships in Systems Medicine - Human Technopole
Are you passionate about science and ready to take the next step in your research journey? Human Technopole is offering up to 9 fully funded PhD scholarships through the highly regarded SEMM PhD Progr...
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Mireya Plass @mireyaplass.bsky.social · 28/07/2025
If you like our recent work and are interested in developing a postdoc project related to isoform diversity in individual cell types and their regulation, get in contact! We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing
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Manuel Irimia @mirimiam.bsky.social · 23/07/2025
🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇
upf.edu
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Eduardo Eyras @edueyras.bsky.social · 18/07/2025
Quantification of transcript isoforms at the single-cell level using SCALPEL nature.com/articles/s41... by @miriplass.bsky.social and her team
nature.com
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
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Dominic Grün @dominicgrun.bsky.social · 21/07/2025
Join our "Advances in Single-Cell Technologies" meeting in December in Freiburg, co-organised with Marco Prinz and @katrinkierdorf.bsky.social. Excellent line-up of speakers covering spatial technologies, lineage tracing, computational methods, and more. www.uniklinik-freiburg.de/single-cell-...
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Facultat de Medicina i Ciències de la Salut @medicinacs-ub.bsky.social · 18/07/2025
L’estudi de #recercaUB sobre l'eina #SCALPEL que ha liderat @mireyaplass.bsky.social s’ha publicat el juliol en #openaccess a la revista @natcomms.nature.com.
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Nextflow @nextflow.io · 17/07/2025
🚨The #NextflowSummit Call for Speakers and Posters is Now Open! 🚨 🎤 Present your talk or poster at the Virtual #NextflowSummit by @seqera.io (Oct 23–24). 📍Or showcase your poster in-person in Barcelona at the Nextflow Training and @nf-co.re Hackathon (Oct 28–29) hubs.la/Q03xGPp_0
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Alfonso Martinez Arias @amartinezarias.bsky.social · 15/07/2025
Two new preprints from the @arjunraj.bsky.social‬ on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about biorxiv.org/content/earl... biorxiv.org/content/earl...
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Qian Cheng @qchengx1e3.bsky.social · 13/07/2025
A computational tool #SCALPEL for #isoform quantification at the single-cell level using 3’ scRNA-seq data @franzake.bsky.social @mireyaplass.bsky.social #BiotechNatureComms doi.org/10.1038/s414...
doi.org
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
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