iiinova — where your digital self keeps evolving

FlyBase @flybase.bsky.social · 21/09/2026

We've updated the Frequently Used GAL4 and Other Binary Drivers resource flybase.org/GAL4/freq_us... with 3 more GAL4 drivers (Scer\GAL4[Adh.PF], Scer\GAL4[c527], and Scer\GAL4[srp.D.cCa]) and added an image to Scer\GAL4[bap.3].

flybase.org

Frequently Used GAL4 Drivers

FlyBase: a database for drosophila genetics and molecular biology

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FlyBase @flybase.bsky.social · 21/09/2026

We've also added 10 new Human Disease Model reports (flybase.org/reports/FBhh... - flybase.org/reports/FBhh...). You can find an index to all Human Disease Models here flybase.org/lists/FBhh/ (linked at the bottom of the Human Disease QuickSearch tab).

flybase.org

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FlyBase @flybase.bsky.social · 21/09/2026

FlyBase has added 11 new #MetabolicPathways reports in FB2026_03 covering AMINO ACID DERIVATIVE METABOLISM flybase.org/reports/FBgg... (1 new report), LIPID METABOLISM flybase.org/reports/FBgg... (6 new reports), and...

flybase.org

Pathway: AMINO ACID DERIVATIVE METABOLISM

FlyBase: a database for drosophila genetics and molecular biology

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FlyBase @flybase.bsky.social · 21/09/2026

Changed in FB2026_03: FlyBase has retired our self-hosted BLAST service. We are directing users to the Alliance of Genome Resources BLAST service www.alliancegenome.org/blastservice (pick Fly Blast from the menu). The BLAST icon on our front page links to there.

The top page of the Alliance BLAST service, with the Fly BLAST link boxed in purple. Other options include Worm BLAST, Yeast BLAST, Fungal BLAST, and Rat BLAST. The text above the menu reads:
Welcome to the BLAST Service for the Alliance of Genome Resources!

This BLAST service allows researchers to search genomic sequences using the Basic Local Alignment Search Tool (BLAST). By entering a sequence or query, users can find regions of similarity to various genomes within the Alliance. This service supports separate environments for each of the Model Organism Databases (MODs) as well as a unified environment for the Alliance. Results provide detailed alignments and annotations to aid in your research. Explore the various BLAST environments through the links below to find the one that best suits your research needs:

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FlyBase @flybase.bsky.social · 18/09/2026

New in FB2026_03! We have launched a beta release of #JBrowse2. All the data tracks you know and love in JBrowse are included in JBrowse2. The older JBrowse will continue to be available on FlyBase.org.

FlyBase JBrowse 2, with the Gene: transcript view; DRSC RNAi amplicons; and RNAseq: Digestive system (FlyAtlas2) tracks opened.

A collapsed menu of all available tracks is visible on the right of the panel.

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Andreas Prokop @poppi62.bsky.social · 18/09/2026

Just rewatched our droso4schools project movie and feel inspired again. Resources are used on 6 continents but Covid took out momentum. Have a look on our webpage (droso4schools.wordpress.com/about/) and watch the film (heads-up @flybase.bsky.social & @fly-eds.bsky.social): youtu.be/DQKFtt3p2C8?...

youtu.be

droso4schools: bringing Drosophila back into classrooms

YouTube video by Manchester Fly Facility

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FlyBase @flybase.bsky.social · 18/09/2026

FlyBase release FB2026_03 is live!

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Alliance of Genome Resources @alliancegenome.bsky.social · 17/09/2026

New Alliance tool just dropped! PAVI (Protein Annotation and Variant Inspector) allows you nalyze protein sequences and variants across model organisms with powerful sequence alignment and annotation tools. Check it out here pavi.alliancegenome.org It's in beta: comments & suggestions are welcome!

pavi.alliancegenome.org

PAVI - Protein Annotation and Variant Inspector

Analyze protein variants and alignments with the Alliance of Genome Resources

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Alliance of Genome Resources @alliancegenome.bsky.social · 17/09/2026

Did you miss today's Alliance webinar, "PAVI: from genome to alignment"? It's now up on the Alliance YouTube channel youtu.be/ZdhXs01D4XE You can register for the October webinar "Disease portals at the Alliance" at www.alliancegenome.org/event-calendar (and find links to all Alliance webinars).

youtu.be

PAVI: From genome to alignment

YouTube video by Alliance Of Genome Resources

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Alliance of Genome Resources @alliancegenome.bsky.social · 16/09/2026

This month's Alliance webinar "PAVI: From genome to alignment", presented by Paulo Nuin, will be TOMORROW Sept 17 noon ET. Join us to hear a preview of the upcoming Alliance variant interface. To get the Zoom link, please register tinyurl.com/4f9ycybt by TONIGHT Sept. 16 (before 11pm ET).

tinyurl.com

Alliance Of Genome Resources Event Registration

Webinar recordings are posted at https://www.youtube.com/@AllianceOfGenomeResources A schedule of future events is on the Alliance Events Calendar https://www.alliancegenome.org/event-calendar

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Alliance of Genome Resources @alliancegenome.bsky.social · 14/09/2026

This month's Alliance webinar "PAVI: From genome to alignment", presented by Paulo Nuin, will be THIS THURSDAY Sept 17 noon ET. Join us to hear a preview of this cool upcoming Alliance tool. To get the Zoom link, please register tinyurl.com/4f9ycybt by this Weds. Sept. 16 (before 11pm ET).

tinyurl.com

Alliance Of Genome Resources Event Registration

Webinar recordings are posted at https://www.youtube.com/@AllianceOfGenomeResources A schedule of future events is on the Alliance Events Calendar https://www.alliancegenome.org/event-calendar

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Shefali @iamshef.bsky.social · 11/09/2026

Hey #Drosophila folks - the #flycross #mentee survey is open for #grad students, #postdoc and #pretenure faculty. ~95 mentors from across the world, with diverse expertise. The co-chairs @shyama13.bsky.social and @jocmcdonald.bsky.social have done a phenomenal work in taking the program forward 🎉

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Alliance of Genome Resources @alliancegenome.bsky.social · 10/09/2026

This month's Alliance webinar "PAVI: From genome to alignment", presented by Paulo Nuin, will be NEXT THURSDAY Sept 17 noon ET. Join us to hear a preview of this cool upcoming Alliance tool. To get the Zoom link, please register tinyurl.com/4f9ycybt by Weds. Sept. 1 (before 11pm ET).

tinyurl.com

Alliance Of Genome Resources Event Registration

Webinar recordings are posted at https://www.youtube.com/@AllianceOfGenomeResources A schedule of future events is on the Alliance Events Calendar https://www.alliancegenome.org/event-calendar

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FlyBase @flybase.bsky.social · 10/09/2026

We are continuing on work to bring FlyBase fully back online. Many more search tools and features are now functioning. JBrowse is back. BLAST is still down, but available at alliancegenome.org.

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FlyBase @flybase.bsky.social · 09/09/2026

We are back up. Report pages and basic search function are now available, but some tools are still offline.

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Brian Calvi @briancalvi.bsky.social · 09/09/2026

We are actively working on it. Stay tuned and visit the Alliance site. @alliancegenome.bsky.social

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FlyBase @flybase.bsky.social · 09/09/2026

FlyBase is currently undergoing emergency maintenance. We hope to be back online tomorrow. In the meantime, a subset of FlyBase data can be accessed at the Alliance of Genome Resources www.alliancegenome.org, including BLAST and JBrowse services.

alliancegenome.org

Alliance of Genome Resources

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Alliance of Genome Resources @alliancegenome.bsky.social · 08/09/2026

This month's Alliance webinar "PAVI: From genome to alignment", presented by Paulo Nuin, will be Thurs. Sept 17 at noon ET. To get the Zoom link, please register tinyurl.com/4f9ycybt by Weds. Sept. 1 (before 11pm ET). Join us to hear about this upcoming new Alliance tool!

tinyurl.com

Alliance Of Genome Resources Event Registration

Webinar recordings are posted at https://www.youtube.com/@AllianceOfGenomeResources A schedule of future events is on the Alliance Events Calendar https://www.alliancegenome.org/event-calendar

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Alliance of Genome Resources @alliancegenome.bsky.social · 04/09/2026

Alliance version 9.1.0 brings major updates to the #AllianceDiseasePortal. We’ve added 6 new disease portals, organized by disease ontology categories. We’ve also added a couple of Community Resources links. #AllianceSkeetorial

The top of the Alliance Disease Portals page. In a purple box shading to pink, the text reads:
Disease Portals
Bringing the power of model systems to the biomedical community
67,404 Genes
11, 427 Alleles
26,409 Models
9 Species

The list of diseases in the Disease Portal. Newly added diseases are indicated with a purple arrow. Text reads:

Disease Portals

Cancer

colorectal cancer 4,167 genes 34 alleles 86 models

Cardiovascular system disease

long QT syndrome 188 genes 17 alleles 19 models

Central nervous system disease

Alzheimer's disease 3,753 genes 304 alleles 1,181 models
epilepsy 5,390 genes 296 alleles 560 models
Parkinson's disease 2,530 genes 377 alleles 1,404 models

Disease of mental health

autism spectrum disorder 1,890 genes 230 alleles 317 models

Disease of metabolism

diabetes mellitus 7,331 genes 189 alleles 357 models

Monogenic disease

ciliopathy 992 genes 136 alleles 172 models

Links to disease resources from the community. Newly added resources are boxed in purple. Text reads:

Disease Portals - Rat Genome Database
FlyBase Human Disease Model Report Index
Human Mouse Disease Connection
Matchmaker Exchange
ModelMatcher
Online Mendelian Inheritance in Man (OMIM)
Portal Kids First DRC

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Alliance of Genome Resources @alliancegenome.bsky.social · 02/09/2026

Alliancegenome.org version 9.1.0 is live, with fresh data and improved features.

alliancegenome.org

Alliance of Genome Resources

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FlyBase @flybase.bsky.social · 02/09/2026

As you may know, NIH abruptly terminated funding to FlyBase curators based in the United Kingdom. Please help us retain these curators and thereby enable ongoing curation of bibliographic, genetic and phenotypic data by contributing annually (tinyurl.com/4jw65mbb). Thank you. #FlyBase

tinyurl.com

FlyBase:Contribute to FlyBase - FlyBase Wiki

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FlyBase @flybase.bsky.social · 01/09/2026

Happy First of September! Enjoy the August #Technical_Advances wiki.flybase.org/wiki/FlyBase... You can have your paper reporting a new resource, technique, or reagent featured in an upcoming month by flagging it when you #FTYP.

wiki.flybase.org

FlyBase:Papers with technical advances - FlyBase Wiki

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Shefali @iamshef.bsky.social · 31/08/2026

Registration for the Midwest #Drosophila meeting is open. It's a wonderful meeting to see the Midwest community. And Allerton is a beautiful venue ! You'll not regret making the trip 🎉 midwest-drosophila-conf.indiana.edu/index.html

midwest-drosophila-conf.indiana.edu

Midwest Drosophila Conference

Join us for the Midwest Drosophila Conference, the perfect small meeting setting to promote interactions among PIs, students, and postdocs. Held each year at the self-contained and historic Allerton P...

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Genetics Society of America @genetics-gsa.bsky.social · 20/08/2026

What keeps scientists coming back to the Annual Drosophila Research Conference year after year? From new collaborations to lasting friendships, mentorship and career-changing opportunities, Dros is more than a meeting—it’s a community. 🔗 Read the blog: buff.ly/AX6jwI4

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Shyama Nandakumar @shyama13.bsky.social · 20/08/2026

Please note that you can sign up to be a FlyCROSS mentor: 1.even if you used Drosophila in the past but do not work with it anymore 2.even if you are in Industry not (especially if you are in Industry or non-academic careers!) 3. even if you are retired! #drosophila

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Brian Wasik @brianrwasik.bsky.social · 20/08/2026

'Without sustained investment, the life sciences risk building an ambitious future on a collapsing foundation.' Hear, hear.

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Katja Röper @katjaroeper.bsky.social · 20/08/2026

Scientific and medical progress will be stunted if we don’t find a way to sustainably fund these important resources!

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MadScientist @mads100tist.bsky.social · 20/08/2026

I am very serious about citing resources (ZFIN, Flybase, Wormbase, yeast, mouse, rat, human, etc) and asking authors to cite them precisely for this reason: the more we talk about them and cite them in our papers, the better chance we have at justifying why we should increase the budget 🧪

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eric lai @lucksmith.bsky.social · 20/08/2026

recent times have made it clear how vital knowledgebases like FlyBase @flybase.bsky.social are to the scientific community. and that they are not simply static websites, but living, dynamic, active entities run by dedicated humans. they require continuous support and can't be taken for granted. 🪰

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FlyBase @flybase.bsky.social · 20/08/2026

Treat biological databases as infrastructure, not projects www.nature.com/articles/d41...

nature.com

Treat biological databases as infrastructure, not projects

Letter to the Editor

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Genetics Society of America @genetics-gsa.bsky.social · 13/08/2026

The pea aphid is an emerging model insect whose genome was misassembled and misannotated due to high levels of gene duplication. In #G3journal, Kevin Deem and Jennifer Brisson present its re-annotated genome to facilitate new analyses of gene duplication and function. 🔗 buff.ly/oawMHbP

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Alliance of Genome Resources @alliancegenome.bsky.social · 12/08/2026

Looking for model organism resources to follow on Bluesky? Here's a starter pack for you! go.bsky.app/Npxsd7h

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FlyBase @flybase.bsky.social · 03/08/2026

August already? Time for the July #Technical_Advances! wiki.flybase.org/wiki/FlyBase... Want your paper reporting a new resource, technique, or reagent featured in a future month? Flag it when you #FTYP.

wiki.flybase.org

FlyBase:Papers with technical advances - FlyBase Wiki

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Genetics Society of America @genetics-gsa.bsky.social · 31/07/2026

Thank you to everyone advocating for genetics research. The GSA Board of Directors submitted a public comment to OMB on the proposed "Regulation for Federal Financial Assistance." Your voice remains essential. Read GSA’s comment here: buff.ly/QFuNpw2

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Alliance of Genome Resources @alliancegenome.bsky.social · 14/07/2026

We are offering a Release Notes preview for Alliance release 9.1.0. This release is NOT LIVE yet. We're making some changes to some API endpoints and downloadable file formats, and want users & developers to be aware of them ahead of time. Details here: www.alliancegenome.org/release-notes

alliancegenome.org

Alliance of Genome Resources

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FlyBase @flybase.bsky.social · 02/07/2026

This unbearably hot July day brings the June #Technical_Advances wiki.flybase.org/wiki/FlyBase... As always, if you want your paper with a new resource, technique, or reagent included in an upcoming month, flag it when you #FTYP.

wiki.flybase.org

FlyBase:Papers with technical advances - FlyBase Wiki

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Gene Ontology @geneontology.bsky.social · 01/07/2026

2026-06-19 GO Release is out 📊 38,263 #GeneOntology terms 🔬 14,736,040 annotations 🦠 171 species 🔗 current.geneontology.org 🚨 File URLs changed, breaking automated downloads-update ASAP 📋 Help & release deets: @alliancegenome.bsky.social forums: community.alliancegenome.org/t/8689 #Bioinformatics

static.klipy.com

Bill Nye The Science Guy: This Changes Everything

ALT: Bill Nye The Science Guy: This Changes Everything

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Genetics Society of America @genetics-gsa.bsky.social · 27/06/2026

Read the latest issue of #G3journal, highlighting challenges in #Drosophila genetic mapping studies, where altered SNP density can skew recombination, complicating trait localization. 🪰 📷️ credit: Jay Hirsh and Morgan et al, 1925 🔗 buff.ly/JJCH6Sj

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FlyBase @flybase.bsky.social · 26/06/2026

New FlyBase commentary: Using AI to get FlyBase data. I'm going to post some brief talking points, but please read the whole thing: flybase.org/commentaries...

flybase.org

Using AI to get FlyBase data

FlyBase: a database for drosophila genetics and molecular biology

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Bloomington Drosophila Stock Center @bdsc.bsky.social · 23/06/2026

We are pleased to announce a major donation to support the work of the Bloomington Drosophila Stock Center. Lawerence Washington, husband of former BDSC director Kathy Matthews, has established an endowment in her honor. bdsc.indiana.edu/news-events/...

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Genetics Society of America @genetics-gsa.bsky.social · 19/06/2026

🎉 Congratulations to GSA members on their election to @nasonline.org, one of the highest honors in science. We’re proud to celebrate their outstanding contributions. 🔗: buff.ly/C5yidrQ 🧵⬇️

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FlyBase @flybase.bsky.social · 19/06/2026

Also in FlyBase release FB2026_02: We have added 5 new drivers the Frequently Used GAL4 And Other Binary System Drivers resource flybase.org/GAL4/freq_us..., for a total of 387 drivers (most with images). This resource includes all GAL4's curated to 20+ papers, & lexA's curated to 15+ papers.

The FlyBase Frequently Used GAL4 and Other Binary System Drivers resource.

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FlyBase @flybase.bsky.social · 19/06/2026

FlyBase release FB2026_02 is live! As of this release we now have 2000 gene group reports🎉, including 1453 ‘classical’ gene group reports flybase.org/lists/FBgg, 399 protein complex reports flybase.org/lists/FBgg/c..., 96 metabolic pathway reports flybase.org/lists/FBgg/m... (continued)

flybase.org

FlyBase - Gene Group List

FlyBase: a database for drosophila genetics and molecular biology

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International Society for Biocuration @biocurator.bsky.social · 18/06/2026

Steven (@steven-flybase.bsky.social) is group manager, curator & nomenclature advisor at FlyBase (@flybase.bsky.social) Cambridge. He leads the FlyBase Gene Group resource, contributes to the Gene Ontology, & collaborates with Rhea, Reactome, RNACentral, UniProt, HGNC, & Alliance of Genome Resources

A man with rectangular glasses in a gray jacket and yellow shirt sits in front of a computer screen and wall mounted map. He is looking away from the screen into the camera.

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International Society for Biocuration @biocurator.bsky.social · 18/06/2026

The International Society for #Biocuration (ISB) would like to congratulate the recipients of the 2026 Excellence in Biocuration Early and Advanced Career awards, Pascal Carme (Early) and Steven Marygold (Advanced)!

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Maria Diaz de la Loza, Scientific Illustrator @mariadiazillus.bsky.social · 16/03/2026

I finally had some time to improve my poster about staging Drosophila embryos in collaboration with @stramerlab.bsky.social and we would like to share this with the community! You can find it here or at a higher resolution on my portfolio: www.behance.net/gallery/2458... #DrosophilaEmbryogenesis

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FlyBase @flybase.bsky.social · 03/06/2026

June already? That must mean the May #Technical_Advances are here wiki.flybase.org/wiki/FlyBase... Flag your paper when you #FTYP if you want your publication with a new resource, technique or reagent included in an upcoming month.

wiki.flybase.org

FlyBase:Papers with technical advances - FlyBase Wiki

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