BACH2 restrains activation of the fetal-haemoglobin-encoding γ-globin genes, while loss of BACH2 enhances NRF2 chromatin occupancy and promotes the formation of activation foci at the γ-globin genes.

An online platform removed 257 papers written or co-written by the University of Chicago’s Nicholas Polson after other academics raised questions.

The Life Sciences Departments in Harvard Faculty of Arts and Sciences seek to recruit a tenure-track professor whose research is at the interface of AI and life sciences, […]

Recent changes in Genentech’s scientific organization, occurring as the company makes artificial intelligence (AI) increasingly central to its research strategy, highlight a broader question facing bi...

TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.

Glycans impact every aspect of physiology. Despite the rapid increase in relevance and translational potential, there remains a lack of tools for studying glycosylation in vivo. Here, we present FlyMO...

Abstract. Coenzyme A is an essential cofactor synthesized from pantothenate, which carries activated acyl groups in cellular metabolic reactions. Coenzyme

Polly Fordyce is building a global engine for protein discovery—one that could help researchers harness AI to create new medicines, materials, and climate solutions.

View Projected Impact of the FY2027 Budget Cuts to the NIH and NSF

Massachusetts Judge Dennis Saylor called the government’s justification for the new rule “absurd.”

Academia must organize now to secure the future of the US academic research enterprise.

Read the declaration and add your name.

During an immune response, metabolism changes dramatically. Metabolites are oxidized to power immune cell functions, serve as building blocks for proliferation, and act as effectors to regulate pathog...

Cryo-EM and genetic analyses reveal that the SWI/SNF chromatin remodeler is an integral component of the transcription pre-initiation complex. The structures demonstrate how SWI/SNF facilitates transcription initiation through stabilization of PIC organization and concerted remodeling of the +1 nucleosome.

The Aydin Lab at Columbia University Irving Medical Center studies how gut microbiota shape the development and plasticity of the enteric nervous system.

By evolving a flavoprotein in mammalian cells, a super-fast, genetically encoded photocatalyst called Lantern was developed, allowing the mapping of dynamic RNA and protein organization at high spatio...

Job #AJO32602, WDR-00061091 Assistant Professor/Open Rank Professor - Chemistry and Chemical Biology, Cornell University (Ithaca, NY), Chemistry and Chemical Biology, Cornell University, Ithaca, New Y...