Researchers have devised a way to visualize molecules that are very rare, very small, or hard to produce naturally, including viruses.

The EMBO workshop ‘Pathogen Immunity and Signaling’ was held from 8 to 11 June 2026 in Leiden, the Netherlands, bringing together 175 participants from 25 countries to discuss the latest advances in a...

Lebrec et al. present a FRET-based cGAS reporter and show that cGAS activation by genotoxic stress is rare and uncoupled from micronuclei. The study implicates R-loop structures and subtypes of chroma...

Sources say health secretary intends to trigger leadership election as early as Thursday

The past two decades of PARP inhibitor synthetic lethality in cancer is explored.

Cryo-EM reveals how kinetochore-microtubule attachment is regulated by Aurora B substrate accessibility on microtubules.

Ostendorf et al. show that activation of liver-X-receptors preconditions T cells to render them more receptive to adopting effector states upon activation.

UK’s research funding body says best scientists are taking posts overseas due to lack of job stability at home

UKRI boss Ian Chapman said it had been told by the government to

Rizzotto et al. discuss the causes and consequences of deregulated mitosis that allow cells arrested in mitosis to escape to the next interphase, where they can initiate inflammatory signalling or und...

Integration of genome-wide association data with epigenomic and chromatin interaction data identifies target genes mediating clear cell renal cell carcinoma risk, implicating disrupted hypoxia signall...

The aim of this course is to provide an overview of epigenetic mechanisms and their links to gene expression and chromatin dynamics, in different systems. The diverse functions of the nucleus involvin...

Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...

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View details and apply for this PDTF - Homologous Recombination Defective Cancers ( Profs Chris Lord and Andrew Tutt) vacancy in Chelsea . Salary: Dependent on relevant Postdoctoral exp...

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

New blow to UK’s key life science sector as industry body says country is losing ground on investment and research

ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al. show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine 41 (C41) during the G2 phase controls its stability. Loss of C41 oxidation increases p21 stability, impairs proliferation, and promotes senescence after irradiation.

A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th

The authors establish the ChIP-CryoEM method, which combines chromatin immunopurification coupled with cryo-electron microscopy, to visualize native human RNAPII elongation complexes in action, with a...

High-fidelity DNA replication is constantly challenged by a diverse range of obstacles, including endogenous lesions and secondary structures in the DNA template, tightly bound protein-DNA complexes, ...