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Aga Gambus

@agagambus.bsky.social
792 followers 260 following 44 posts

Researcher, group leader, professor, mum of 2. Interested in DNA replication and damage, ubiquitylation, cell cycle, molecular and structural biochemistry.

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Aga Gambus @agagambus.bsky.social · 01/10/2026
Our ERC-funded MOBILITY fellowships are now open for applications! If you are interested in starting your independent career within Molecular Biodiscovery at University of Birmingham - check out www.birmingham.ac.uk/mobility or join us for webinar - registration on the website! Share please 🙏
birmingham.ac.uk
MOBILITY - University of Birmingham
Retaining Europe's brightest researchers to drive the next generation of life science breakthroughs.
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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · 11/09/2026
We’re hiring! 🧬 We're looking for a Postdoctoral Training Fellow to join our group at the ICR in London and work on chromatin biology, transcription regulation and AML. Curious about how histone modifications shape gene regulation and cell identity? Come join us! jobs.icr.ac.uk/vacancies/15...
jobs.icr.ac.uk
Postdoctoral Training Fellow - Chromatin Biology and Epigenetics in Chelsea | The Institute of Cancer Research
View details and apply for this Postdoctoral Training Fellow - Chromatin Biology and Epigenetics vacancy in Chelsea . Salary: Salary range £45,600 - £51,450 per annum. Dependent on re...
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Biochemical Society @biochemsoc.bsky.social · 04/09/2026
And that’s a wrap! A huge thank you to everyone who joined us for UK DNA 2026, from our speakers and session chairs to everyone who presented, asked questions and shared their research. Thank you for making it such an engaging and enjoyable conference.
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The Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · 07/09/2026
ℹ️ lister-institute.org.uk/research-pri...
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Aga Gambus @agagambus.bsky.social · 21/08/2026
New ERC Co-fund MOBILITY fellowships at University of Birmingham, UK. 6 outstanding postdoctoral researchers will be awarded 5-year fellowships to develop their independent future career. All within the umbrella of Molecular Biodiscovery. Details at: www.birmingham.ac.uk/mobility Please share!
birmingham.ac.uk
MOBILITY - University of Birmingham
Retaining Europe's brightest researchers to drive the next generation of life science breakthroughs.
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Aga Gambus @agagambus.bsky.social · 21/08/2026
New ERC Co-fund MOBILITY fellowships at University of Birmingham, UK. 6 outstanding postdoctoral researchers will be awarded 5-year fellowships to develop their independent future career. All within the umbrella of Molecular Biodiscovery. Details at: www.birmingham.ac.uk/mobility Please share!
birmingham.ac.uk
MOBILITY - University of Birmingham
Retaining Europe's brightest researchers to drive the next generation of life science breakthroughs.
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Hasan Yardimci @hyardimci.bsky.social · 20/08/2026
Delighted to share our latest publication, a collaborative work with @hanasedlackova.bsky.social and @puckknipscheer.bsky.social. Grateful to everyone who contributed to this project. www.cell.com/cell-reports...
cell.com
FANCJ and RTEL1 facilitate pre-replication complex disassembly following replisome collision
Cameron et al. show that dormant pre-replication complexes are removed upon collision with replication forks in Xenopus egg extracts. They identify FANCJ and RTEL1 as key factors in this process and s...
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Aga Gambus @agagambus.bsky.social · 18/07/2026
We’ve been awarded European Commission Choose Europe for Science Co-fund at Uni of Birmingham! MOBILITY will fund 6 talented postdoctoral researchers at the transition to independence. All within remit of Molecular Biodiscovery. Applications open in October 😀👍. www.birmingham.ac.uk/news/2026/bi...
birmingham.ac.uk
First UK institution awarded Choose Europe for Science grant - University of Birmingham
Birmingham awarded £1.2m in ERC funding to attract talent from outside of Europe
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Aga Gambus @agagambus.bsky.social · 18/07/2026
We’ve been awarded European Commission Choose Europe for Science Co-fund at Uni of Birmingham! MOBILITY will fund 6 talented postdoctoral researchers at the transition to independence. All within remit of Molecular Biodiscovery. Applications open in October 😀👍. www.birmingham.ac.uk/news/2026/bi...
birmingham.ac.uk
First UK institution awarded Choose Europe for Science grant - University of Birmingham
Birmingham awarded £1.2m in ERC funding to attract talent from outside of Europe
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Tatiana Moiseeva @tat1anamoiseeva.bsky.social · 15/07/2026
Our lab at Pitt is looking to hire a technician. Ideal candidate would be a recent graduate with some cell biology skills, looking to expand their experience before applying to a PhD program in a couple of years. If you are this person, interested in DNA replication, please email me. moiseevalab.com
moiseevalab.com
Tatiana Moiseeva Lab
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The EMBO Journal @embojournal.org · 09/07/2026
Why are telomeres endogenous sources of replication stress? Max Douglas and collaborators use reconstituted human replisomes with telomeric templates to dissect how core components of telomeres influence different aspects of the replication process link.springer.com/article/10.1...
link.springer.com
Inhibition of lagging strand replication by G-rich telomeric DNA and the shelterin subunit POT1 - The EMBO Journal
Telomeres preserve stable eukaryotic chromosomes by protecting the natural chromosome ends from DNA repair but pose a persistent challenge to the replication machinery and an endogenous source of repl...
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Nucleic Acids Research @narjournal.bsky.social · 08/07/2026
📣 Applications are open for the next NAR Early Career Investigator (ECI) Advisory Board cohort! Work with Executive Editors, help shape journal strategy, and gain insight into peer review during a 2-year term. Apply by 1 Nov 2026: lnkd.in/g233ZCAf #ECR #NAR #AcademicPublishing #MolecularBiology
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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · 08/07/2026
1/ Very excited to share the first publication from my lab! In this work, we developed an efficient strategy to precisely mutate mammalian histone genes in their native genomic context using CRISPR prime editing: www.nature.com/articles/s41...
nature.com
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing - Nature Genetics
This study uses a precise and efficient clustered regularly interspaced short palindromic repeats (CRISPR) prime editing system to substitute lysine residues in histone H3, individually or in combinat...
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Pedro Beltrao @pedrobeltrao.bsky.social · 06/07/2026
My department @eth-dbiol.bsky.social at ETH Zurich is hiring for a tenured professor in mol cell bio and biochemistry (associate/full). The position is within the Institute of Biochemistry (www.bc.biol.ethz.ch) and it is fairly open within their scope of research. www.nature.com/naturecareer...
nature.com
Professor of Molecular Cell Biology and Biochemistry - Zurich, Switzerland job with ETH Zurich | 12861386
The Department of Biology at ETH Zurich invites applications for the above-mentioned tenured professorship at the Institute of Biochemistry
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Nitika Taneja @TanejaLab @nitikataneja.bsky.social · 01/07/2026
Very excited to share our new Nature study! We discovered that replication stress stabilizes CTCF-dependent chromatin loops enclosing stressed nascent DNA, where G9a-mediated heterochromatin protects it from nucleolytic degradation. rdcu.be/frzLg Huge thanks to all our collaborators and co-authors!
nature.com
Replication-stress-induced chromatin loops protect fork stability - Nature
Replication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks.
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UoB Advanced Research Computing delivering BEAR services @uob-bear.bsky.social · 26/06/2026
AlphaFold is transforming how we study DNA replication, predicting protein structures and interactions to unlock new biological insights. A powerful example of AI+HPC accelerating discovery. blog.bham.ac.uk/bear/2026/06... @unibirmingham.bsky.social @agagambus.bsky.social #AlphaFold #Bioinformatics
blog.bham.ac.uk
AlphaFold protein structure prediction to study DNA replication – Birmingham Environment for Academic Research
Postdoctoral researcher advancing DNA replication research using biochemistry, cryo-EM, and AlphaFold on BlueBEAR to reveal genome protection mechanisms.
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James Dewar @jamesmdewar.bsky.social · 28/05/2026
🧬 ⛓️‍💥 Our paper is now out in @natsmb.nature.com ! We examined the fate of replication forks that collapse at single-strand DNA breaks (SSBs) in vertebrates 🐸, comparing the consequences of collapse at single vs convergent forks. www.nature.com/articles/s41...
nature.com
Distinct repair outcomes from single and convergent replication fork collapse - Nature Structural & Molecular Biology
Here the authors show that collapse of single replication forks causes recombination, end fusions or degradation but does not restart DNA synthesis. In contrast, collapse of convergent forks completes...
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Dirk Remus @dirkremus.bsky.social · 13/06/2026
If you have experience in biochemistry/cryo-EM, are interested in DNA replication, and would like to do a postdoc in New York - our lab has positions available! Just DM or email me with your CV.
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Gonçalo Castelo-Branco @gocastelobranco.bsky.social · 01/06/2026
Come and start your group at @ki.se! ki.se/en/about-ki/...
ki.se
Assistant Professor recruitment programme 2026
Karolinska Institutet continues to grow a global community of excellence. In summer 2026, KI is inviting applications for 21 Assistant Professor positions in medicine and health. We are once again loo...
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Francesca Mattiroli @fmattiroli.bsky.social · 30/04/2026
We are looking for a PhD student to study chromatin changes related to heart regeneration, in collaboration with @bakkerslab.bsky.social . Please share and apply! www.hubrecht.eu/nl/vacature/...
hubrecht.eu
PhD student - 38 hours p/w - Hubrecht Institute
We are looking for PhD student in the group of Dr. Francesca Mattiroli at the Hubrecht Institute. The successful candidate will work in a collaborative project between the Mattiroli lab and the lab of...
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Alexis Barr @alexisbarr.bsky.social · 29/04/2026
Excellent opportunity @mrc-lms.bsky.social for a human physiologist to start their own group. Deadline 4th May. Core funding, excellent package. Please repost! lms.mrc.ac.uk/work/vacanci...
lms.mrc.ac.uk
Programme Leader Track - MRC Laboratory of Medical Sciences
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Aga Gambus @agagambus.bsky.social · 24/04/2026
The University of Birmingham’s College of Medicine and Health is offering a 2-year Springboard Fellowship to help you start your own lab. Previous award holders have secured externally funded fellowships. Deadline: 8th June 2026 17:00 BST The Fellowship Academy www.birmingham.ac.uk/about/colleg...
birmingham.ac.uk
Internal Funding Opportunities - University of Birmingham
The University of Birmingham and College of Medicine and Health provide several funding opportunities to research-active staff looking to further develop their research activity.
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Aga Gambus @agagambus.bsky.social · 24/04/2026
Congratulations to Dr Tianyi Zhang and Dr Layara Abiko@layaraabiko.bsky.social, who are recipients of Career Development Awards from Wellcome Trust. www.birmingham.ac.uk/news/2026/su...
birmingham.ac.uk
Success for Birmingham researchers in Wellcome Career Development Awards - University of Birmingham
Researchers at the University of Birmingham have been successful in the most recent round of the Wellcome Career Development Awards.
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Best for Britain @bestforbritain.org · 15/04/2026
It’s official: the UK is rejoining Erasmus! 👏🇪🇺
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Biochemical Society @biochemsoc.bsky.social · 14/04/2026
We're delighted to announce Professor Daniel Tennant as the recipient of the 2027 Sir Philip Randle Lecture! Work in the Tennant Research Group - Birmingham UK has been instrumental in identifying new pathways through which cells modify their metabolism under hypoxia.
Portrait of Professor Daniel Tennant, University of Birmingham, featured for The Sir Philip Randle Lecture at The Biochemical Society 2027 Awards.
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Kelly Nguyen @kellythd-nguyen.bsky.social · 26/03/2026
Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...
youtube.com
Cryo-EM structure of yeast telomerase
YouTube video by MRC Laboratory of Molecular Biology
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The Francis Crick Institute @crick.ac.uk · 23/03/2026
“I think it’s a real mistake to forget where the pipeline for all this begins.” John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it. www.crick.ac.uk/news/2026-03...
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Jessica Blair @jessicamablair.bsky.social · 19/03/2026
PhD available with @overtonlab.bsky.social Sara Jabbari and me associated with our BBSRC sLoLa project! www.findaphd.com/phds/project... (UK students only)
findaphd.com
Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham on FindAPhD.com
PhD Project - Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham, listed on FindAPhD.com
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Rob Klose @robklose.bsky.social · 13/03/2026
We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).
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Kathrin Lang @klanglab.bsky.social · 11/03/2026
🚨 Our new paper is out! 🙌 Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs. We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs. www.cell.com/chem/fulltex... 1/4
cell.com
A modular genetic code expansion approach to site-specific lysine acylations
A modular strategy combining genetic code expansion with a selective amide bond-forming reaction enables the site-specific installation of lysine acylations on folded proteins. Acylboronates react sel...
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Alper Akay @alperakay.bsky.social · 06/03/2026
PhD position in our lab - 4-year funded by BBSRC and @nrpdtp.bsky.social in collaboration with @earlhaminst.bsky.social and Inspiralis Ltd. Open to UK fee qualifying students - UK citizens and citizens of Ireland (residency requirement), etc biodtp.norwichresearchpark.ac.uk/projects/how...
biodtp.norwichresearchpark.ac.uk
How do RNA molecules shape genome regulation in the nervous system? (AKAY_U26CASE) | Doctoral Training Partnership
This is open to Home Fee Status candidates only. This PhD project will investigate how RNA modifications influence the activity of topoisomerase I (TOP1), a crucial enzyme that regulates DNA…
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Nilsson lab @nilssonlab.bsky.social · 06/03/2026
Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...
nature.com
A proteome-wide dependency map of protein interaction motifs - Nature Structural & Molecular Biology
Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...
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Lori Passmore @lapassmore.bsky.social · 25/02/2026
We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab. @mrclmb.bsky.social Please get in touch if you have any questions. www.nature.com/naturecareer...
nature.com
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Cambridge, Cambridgeshire (GB) job with MRC Laboratory of Molecular Biology (LMB) | 12854636
Research Group Leader Tenure Track Starting Salary £67,979 to £76,868 per annum MRC Laboratory of Molecular Biology, Cambridge, UK The MRC Laborato...
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The Groth lab @grothlab.bsky.social · 25/02/2026
DNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!
cell.com
Post-replicative chromatin accessibility predicts cell fate change
Knudsen and colleagues use repli-ATAC-seq to compare replicated and unreplicated chromatin in two models of cell identity change. They find that lineage-specific elements are accessible earlier in rep...
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Aga Gambus @agagambus.bsky.social · 25/02/2026
Best conference location ever! Thank you @fusionconf.bsky.social for the excellent DNA replication and repair conference 👍👍👍
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Adrian Saurin @adesaurin.bsky.social · 22/02/2026
I have multiple positions available to join my lab from this summer: #postdoc, #student and #technician. Adverts to follow but see www.saurinlab.com for further details. #senescence, #mitosis, #cellcycle, #phosphorylation are the key areas. Email me if interested.
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Bertolin Lab @bertolinlab.bsky.social · 18/02/2026
To kickstart this new Bluesky account: We're hiring! The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab. Details in the flyer — get in touch! 👇
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Ferenc Mueller @ferencmueller.bsky.social · 17/02/2026
We are hiring 2 Postdoctoral fellows for our lab (www.mueller-lab.org): 1, Transcription control of metabolic adaptation in development (shorturl.at/oeG6U). 2, Semantic rules of developmental gene regulation (shorturl.at/KdHmJ) #jobs #transcription #zebrafish #zebrafishrock #IZFS
shorturl.at
Research Fellow at University of Birmingham
Discover Research Fellow jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.
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Sjors Scheres @sjorsscheres.bsky.social · 16/02/2026
Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...
mrc.tal.net
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council
Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55
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ME Torres-Padilla @metorrespadilla.bsky.social · 09/02/2026
We go live!!! Join us Munich July5-7th to hear exciting research on #Replication by leaders in the field AND !! registration is FREE 🥳 (but mandatory) - we hope to see many in Munich 🍺 @helmholtzmunich.bsky.social @replifate.bsky.social @epicrossborders.bsky.social replifate.eu/event/meetin...
replifate.eu
Events for February 2026
06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding how DNA replication...
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Dirk Remus @dirkremus.bsky.social · 06/02/2026
Happy to share our perspective on the DNA translocation mechanism by the CMG helicase. DNA translocation by the CMG helicase: the helical inchworm model url: portlandpress.com/biochemsoctr...
portlandpress.com
DNA translocation by the CMG helicase: the helical inchworm model
Abstract. In all cells, hexameric helicases drive the unwinding of parental chromosomal DNA at replication forks to provide the single-stranded DNA templates required by replicative DNA polymerases. D...
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Lopes_Lab @lopeslab.bsky.social · 29/01/2026
Don't miss the opportunity to attend exciting virtual talks from leading scientists in genome integrity, provided by the @genomeiinetwork.bsky.social! Next one is in a few days 👇
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Christian Speck @speck-lab.bsky.social · 19/01/2026
📢 One more week to go... exciting fully funded #PhD position for UK candidates to work across #ICR and #Imperial on novel mechanisms in genome stability and #CancerResearch. #PhDStudentship #LifeSciences #DNAReplication #CRISPR
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Luijsterburglab @luijsterburglab.bsky.social · 17/01/2026
Great response so far for the DNA Repair Meeting in April 2026 ! 🧬 A few poster spots are still available. ✨ Early-bird registration extended to February 28th ✨ New invited speakers added: check the site: dnarepairmeeting-egmond2026.com Don’t miss this outstanding meeting!
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Lopes_Lab @lopeslab.bsky.social · 08/01/2026
One more upcoming appointment with great science via the Genome Integrity Italian Network (GiiN). Don't miss it, just join via the link 👇
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Biochemical Society @biochemsoc.bsky.social · 05/01/2026
Sign up for the Biochemical Society’s original R course, R101! Suited for beginners, this course will teach you how to get data into R, and manipulating and visualising this using various methods. 🧪 ow.ly/O0ga50XNCuX
R for Biochemists 101
2 February 2026
Register online
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Lori Passmore @lapassmore.bsky.social · 05/01/2026
Alessandro Costa @costalaboratory.bsky.social, Dana Branzei and myself are co-organising the 2026 Machines on Genes meeting in beautiful Crete as the 94th Harden Conference hosted by @biochemsoc.bsky.social Register now - lots of opportunities for selected talks www.eventsforce.net/biochemsoc/f...
eventsforce.net
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MRC AIM DTP @mrcaimdtp.bsky.social · 12/12/2025
Applications still OPEN for MRC fully funded PhD studentships 🎓✨ Join world-class researchers across our 3 partner universities: 🔹 @unibirmingham.bsky.social 🔹 @uniofleicester.bsky.social 🔹 @uniofnottingham.bsky.social 🌍 Open to applicants worldwide 👉 Apply more.bham.ac.uk/mrc-aim/phd-...
more.bham.ac.uk
PhD Opportunities – MRC AIM
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Aga Gambus @agagambus.bsky.social · 03/12/2025
💡 PhD student position at the University of Birmingham, UK. Fully funded by MRC AIM doctoral training programme. 4 years. Open to 🇬🇧 🇪🇺 & 🌎. DNA replication 🧬 . Collaboration with Prof Andrew Wilson (Chemistry). Deadline midday (GMT) 9 January 2026. Please share 😀👍 www.findaphd.com/phds/project...
findaphd.com
Peptidomimetic Inhibition of DONSON/GINS as an experimental tool and potential an@cancer strategy at University of Birmingham on FindAPhD.com
PhD Project - Peptidomimetic Inhibition of DONSON/GINS as an experimental tool and potential an@cancer strategy at University of Birmingham, listed on FindAPhD.com
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GIIN @genomeiinetwork.bsky.social · 03/12/2025
❄️The 2026 Winter Session of GIIN Webinars is here! Join us on the first Tuesday of each month at 5 PM (Rome) / 11 AM (NYC). No pre-registration needed, simply join via Zoom: uniroma1.zoom.us/j/95149984403 Want reminders? Subscribe here: docs.google.com/forms/d/e/1F...
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