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Elsässer Lab

@simonelsasser.bsky.social
817 followers 359 following 87 posts

elsaesserlab.wordpress.com PI @ Karolinska Institutet Co-Founder @ Epigenica Ab Loves Science, Chromatin and Epigenetic, Synthetic Biology, Microproteins, all of it!

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Elsässer Lab @simonelsasser.bsky.social · 24/03/2026
We have a research/technical assistant (E7, 100%) opening uni-freiburg.de/en/job/00004...! For those not familiar with German university staff, this is a permanent position requiring a technical assistant training (BTA/CTA MTLA) or BSc degree, transparent pay scale: lbv.landbw.de/documents/d/...
uni-freiburg.de
University of Freiburg
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Baden-Württemberg Stiftung @bwstiftung.bsky.social · 19/01/2026
👩‍🏫👨‍🏫Mit dem 𝘌𝘭𝘪𝘵𝘦𝘱𝘳𝘰𝘨𝘳𝘢𝘮𝘮 𝘧ü𝘳 𝘗𝘰𝘴𝘵𝘥𝘰𝘤𝘴 unterstützen wir exzellente Wissenschaftler:innen auf ihrem Weg zur Professur.⏰ Bis zum 22. April können Hochschulen exzellente Postdocs nominieren. ➡️Hier mehr erfahren: www.bwstiftung.de/Eliteprogramm
bwstiftung.de
Eliteprogramm für Postdocs - Baden-Württemberg Stiftung
Die Hochschulen müssen die ausgewählten Antragstellerinnen und Antragsteller bis 22. April 2026 (12.00 Uhr) der Baden-Wü…
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SciLifeLab @scilifelab.se · 02/12/2025
“#Microproteins like PIPPI may turn out to be important regulators of how cells respond to stress, and could offer new clues for understanding disease mechanisms,” says @simonelsasser.bsky.social, Group Leader at SciLifeLab and @ki.se ↓🧪 Learn more: www.scilifelab.se/news/cancer-...
scilifelab.se
Cancer cells overcome stress with new microprotein uncovered by scientists at SciLifeLab
The researchers have tested more than 11,000 potential microproteins to identify which affect cell survival during stress, something that could lead to new therapies. Researchers in the Elsässer, Piaz...
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Elsässer Lab @simonelsasser.bsky.social · 23/10/2025
Because of the nice Google Doodle I was drawn into a conversation with AI about base pairing...
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Elsässer Lab @simonelsasser.bsky.social · 16/10/2025
This is very cool @odedrechavi.bsky.social. Do I understand correctly that it works with the text of the manuscript, not with figures or data? My concern with current production rate is that papers may be written skilfully and claims are clear, but they are not adequately supported by the data...
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Elsässer Lab @simonelsasser.bsky.social · 16/10/2025
Deeply grateful to @carlzeissstiftung.bsky.social, I'm very much looking forward to realising this ambitious, long term project with your support. An thank you for the little CARL ZEISS I received with my mail today, he's already on top of his first experiments in our lab at @uni-freiburg.de 😀
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Elsässer Lab @simonelsasser.bsky.social · 16/10/2025
Deeply grateful to @carlzeissstiftung.bsky.social, I'm very much looking forward to realising this ambitious, long term project with your support. An thank you for the little CARL ZEISS I received with my mail today, he's already on top of his first experiments in our lab at @uni-freiburg.de 😀
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Elsässer Lab @simonelsasser.bsky.social · 19/09/2025
#Jobalert 🚨: looking for a #computationalbiology expert with track record in analysis, integration and interpretation of #omics datasets, in particular #epigenomics, #singlecellgenomics, #proteomics data. uni-freiburg.de/stellenangeb... short deadline 30th September!
uni-freiburg.de
Universität Freiburg
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Elsässer Lab @simonelsasser.bsky.social · 19/09/2025
And now off to the 5th Liquid Biopsy Meeting @uniklinik-fr.bsky.social
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Elsässer Lab @simonelsasser.bsky.social · 19/09/2025
Today I have been officially appointed to full Professor at @uni-freiburg.de 🎉.
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Dr. Peter Walentek (Walentek Lab) @walenteklab.bsky.social · 16/06/2025
Save the date 📅! Our TriNational #devbio #stemcell Meeting 2025 will be held in Freiburg on Sept. 19th. As always, participation is free and talks will be selected from early career scientists. Joun us 😊 Info: devstemcell.org/home @biozentrum.unibas.ch @uni-freiburg.de @igbmc.bsky.social
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Elsässer Lab @simonelsasser.bsky.social · 16/06/2025
Congratulations Koichi Sato and @puckknipscheer.bsky.social for a biochemistry tour de force! Sooo many in vitro experiments, pinning down step by step a mechanism to resolve G4 structures. We used KOs and quantitative G4 CUT&Tag to corroborate mechanism in mouse ESC. www.science.org/doi/full/10....
science.org
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Elsässer Lab @simonelsasser.bsky.social · 16/06/2025
Fantastic collaboration with @puckknipscheer.bsky.social 👏! Congrats to all!
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Elsässer Lab @simonelsasser.bsky.social · 15/06/2025
i was hoping Bsky would understand *markdown* 🙄
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Elsässer Lab @simonelsasser.bsky.social · 15/06/2025
PhD or Postdoc interested working on your own or collaborative project at @uni-freiburg.de? Apply to [Freiburg Rising Star Academy](uni-freiburg.de/frsa/). [Info Session](forms.office.com/e/G9LSAsFuWU) on June 23. Get in touch if you'd like to join us at [CIBSS](uni-freiburg.de/frsa/applica...)
uni-freiburg.de
Application – Freiburg Rising Stars AcademyText icon 'Universität Freiburg'Text icon 'UFR' standing for University of FreiburgSeal element of the university of freiburg in the shape of a flowerSearch ...
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Elsässer Lab @simonelsasser.bsky.social · 11/06/2025
Finally found it! researchagora.com, very interesting development, will try it out
researchagora.com
Research Agora – Better research, together.
We address the reproducibility crisis and the need for fair assessment reform, converting unpublishable results into recognized scientific contributions
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Elsässer Lab @simonelsasser.bsky.social · 11/06/2025
I found DeCci Labs desci.com, looks interesting, but exactly what I am remembering
desci.com
DeSci Labs – Empowering Researchers from Data to Publication
DeSci Labs helps researchers manage, store and publish data with AI-powered insights and workflows to boost chances of publishing in top journals.
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Elsässer Lab @simonelsasser.bsky.social · 06/06/2025
❤️
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Elsässer Lab @simonelsasser.bsky.social · 05/06/2025
also anyone with an apt/house for rent in #freiburg, 4+ rooms, preferably Herdern, Güterbahnhof, Wiehre, ANY time, ANY price, SEND IT MY WAY
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Elsässer Lab @simonelsasser.bsky.social · 05/06/2025
Incredibly grateful for this tremendous recognition by @humboldt-foundation.de and not possible without the strongest support from @uni-freiburg.de and many previous funding bodies that made our research possible www.humboldt-foundation.de/en/explore/n...
humboldt-foundation.de
Four new Alexander von Humboldt Professors selected
Germany’s most valuable research award goes to Aachen, Berlin, Freiburg and Göttingen.
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Elsässer Lab @simonelsasser.bsky.social · 05/06/2025
This is a joint achievement by everyone who contributed to the elsaesserlab.wordpress.com over the past 10 years and I am so looking forward to our big 10-year reunion next week ❤️
elsaesserlab.wordpress.com
The Elsässer Lab at Karolinska Institutet
LABORATORY OF CHEMICAL AND SYNTHETIC SYSTEMS BIOLOGY
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Elsässer Lab @simonelsasser.bsky.social · 05/06/2025
📣 I will take up a Professorship at @uni-freiburg.de, Faculty of Biology. With amazing funding news coming in, we'll be in a position to establish a major research program around Epigenetics, Signaling and Synthetic Biology at the Signalhaus @cibss.bsky.social. More news and job ads to come soon!
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Elsässer Lab @simonelsasser.bsky.social · 31/05/2025
Do you sometimes feel research is 🎶 on step forward and two steps back 🎶? Well the good thing about a marathon is that no matter how slow you go, you are always getting closer to the finish line 😅. #stockholmmarathon ✌️
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Elsässer Lab @simonelsasser.bsky.social · 19/05/2025
We are looking for MSc students interested in joining us for a bioinformatics thesis project. The task is to analyze existing epigenomics datasets, explore data from different technical and biological angles, generate reproducible code and figures to be incorporated into manuscripts #jobalert
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Elsässer Lab @simonelsasser.bsky.social · 16/05/2025
hoping for swarm intelligence: came across a new publishing platform that allowed to publish small experiment units or attach new experiments to existing publications (e.g. 'this result confirms figure 3A in paper X'), together community peer review. Problem: I can't find the website anymore. HELP!
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Elisabeth Bik @elisabethbik.bsky.social · 06/04/2025
Climate-change deniers use Grok AI to write a climate-change denier article, and published that in a climate-change denial journal. They even had to 'steer' Grok a couple of times, because its text was not climate-change denier enough.
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Elsässer Lab @simonelsasser.bsky.social · 28/03/2025
www.theguardian.com/environment/... wow never new what that came through the pipes in our basement :)
theguardian.com
‘The heat you need at a reasonable price’: how district heating can speed the switch to clean energy
In Sweden, most residential heating and hot water comes from heating networks – helping to pool resources and innovation
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Universität Freiburg @uni-freiburg.de · 28/03/2025
Von Infektionen, Symbiosen und Tumorzellen: Wie interdisziplinäre Grundlagenforschung im Freiburger Exzellenzcluster @cibss.bsky.social Innovationen in #Biomedizin und #Pflanzenforschung hervorbringt: ufr.link/cibss-forschungsansaetze
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Elsässer Lab @simonelsasser.bsky.social · 09/03/2025
Beautiful work!!
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Elsässer Lab @simonelsasser.bsky.social · 06/03/2025
as well as thanks to @cp-iscience.bsky.social @cellpress.bsky.social
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Elsässer Lab @simonelsasser.bsky.social · 06/03/2025
...but please do read the latest version, with deepened mass spec support and additional analyses. And a final thanks for being in for the long haul Dörte, Lorenzo, Carmen, @plantproteomics-ms.bsky.social @thomasmartinez.bsky.social, @luzeenaraja.bsky.social co-authors! www.cell.com/iscience/ful...
cell.com
A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness
molecular genetics, classification of proteins, methodology in biological sciences, cancer, and cell biology
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Elsässer Lab @simonelsasser.bsky.social · 06/03/2025
It feels a little bit postclimactic to post this now, after the first version of our paper hit bioRxiv when X was still a thing that people used, the revised version was formally accepted at Cell Community past November. But here is the final print version of our paper www.cell.com/iscience/ful...
cell.com
A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness
molecular genetics, classification of proteins, methodology in biological sciences, cancer, and cell biology
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Karolin Luger @nucleosomepolice.bsky.social · 01/03/2025
🧪what with the demolition of #NIH funded #research, where, dare I ask, are our friends from #bigpharma? y'all good? mooched enough off of public-access NIH-funded research? Stocked up with PhD level scientists who were trained on NIH training grants to tide you over until Academia comes back?
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François Lallemend @flallemend.bsky.social · 04/02/2025
A great line-up of speakers for the "Blueprints of life: cell fate choices and lineages" conference @ki.se organized by @anderssonlab.bsky.social To register 👇 news.ki.se/calendar/blu...
news.ki.se
Blueprints of Life: Cell fate choices and lineages
Dive into the fascinating world of cell fate decisions that underlie the variety of cell types in our bodies. Join top researchers in the field to uncover the blueprints of life!
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Elsässer Lab @simonelsasser.bsky.social · 15/02/2025
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Elsässer Lab @simonelsasser.bsky.social · 14/01/2025
Exciting talk today by @arnaudkr.bsky.social @scilifelab.se
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Elsässer Lab @simonelsasser.bsky.social · 09/01/2025
The @theguardian.com has made just a short list of the kind of insults you can now post on Facebook. It’s ugly 🤮. www.theguardian.com/technology/2...
theguardian.com
Revisions of ‘hateful conduct’: what users can now say on Meta platforms
Meta has rewritten policies to allow different things to pass on Facebook, Instagram and Threads
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Elsässer Lab @simonelsasser.bsky.social · 22/12/2024
❤️ Hometown
Schwäbisch Hall, Germany
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Elsässer Lab @simonelsasser.bsky.social · 22/12/2024
Thanks for a fantastic year with Elsässerlab and Epigenica Ab!
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Science News @scinews.bsky.social · 19/12/2024
Just let me be a scientist: The experienced, highly qualified postdoc is a valuable resource. PDF download www.embopress.org/doi/epdf/10....
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Elsässer Lab @simonelsasser.bsky.social · 12/12/2024
It’s #Nobel week 🥂 #Stockholm @nobelprize.bsky.social
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Elsässer Lab @simonelsasser.bsky.social · 11/12/2024
and another #bioRxiv alert: new study from Tovah Day Lab cos.northeastern.edu/people/tovah... Chemical screen for #G4 modifiers www.biorxiv.org/content/10.1...
biorxiv.org
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability
DNA G-quadruplexes (G4s) are secondary structures with significant roles in regulating genome function and stability. Dysregulation of the dynamic formation of G4s is linked to genomic instability and...
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Elsässer Lab @simonelsasser.bsky.social · 09/12/2024
seems like I messed up my #bioRxiv alert thread, so here is /1 again: It's PIPPI! continue here ▶️ bsky.app/profile/simo...
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Elsässer Lab @simonelsasser.bsky.social · 09/12/2024
But let's start from the beginning www.biorxiv.org/content/10.1...: Lorenzo cloned a library of > 10000 sORFs to performed pooled screens. Subjecting cancer cells to 6-thioguanine, two sORFs conferred increased survival: AltDDIT3 (-> elifesciences.org/articles/27860) ... \2
biorxiv.org
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response
Microproteins encoded by short open reading frames (sORFs) of less than 100 codons have been predicted to constitute a substantial fraction of the eukaryotic proteome. However, relevance and roles of ...
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Elsässer Lab @simonelsasser.bsky.social · 09/12/2024
with Dörte's paper soon out in a journal (but not too late to read on bioRxiv, PM me for revised version www.biorxiv.org/content/10.1...), it is time for a new #microprotein preprint 👇
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The Lewis Lab @peterlewislab.bsky.social · 29/11/2024
O hai, calico kittehs! 🐾 Their patchy fur iz from a sneaky X-chromosome hack. Arhgap36 goes rogue, says "Nope" to normal signals, and makes orange spots happen. Melanocytes be like “no PKA 4 u!” 😽 www.biorxiv.org/content/10.1...
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Elsässer Lab @simonelsasser.bsky.social · 28/11/2024
In Milan, visiting EIO tomorrow
Street in Milan, Italy
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Elsässer Lab @simonelsasser.bsky.social · 28/11/2024
Very impressed by Shriprakash who I crossed paths with some years back. While searching a PhD supervisor, he pursued his independent work, leading to this peer review single author paper in @oxunipress.bsky.social doi.org/10.1093/intb...
doi.org
Machine learning ranking of plausible (un)explored synergistic gene combinations using sensitivity indices of time series measurements of Wnt signaling pathway
Abstract. Combinations of genes or proteins work in synergy at different times and durations in a signaling pathway. However, which combinations are preval
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Elsässer Lab @simonelsasser.bsky.social · 22/11/2024
Poster Prize Winners 🏆 #EMBLOmics
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Elsässer Lab @simonelsasser.bsky.social · 22/11/2024
Last talk at #EMBLOmics by Nicolai Slavov spanning alternative proteoforms, single cell proteomics technology and emerging insights @slavov-n.bsky.social
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