The EMBO workshop ‘Pathogen Immunity and Signaling’ was held from 8 to 11 June 2026 in Leiden, the Netherlands, bringing together 175 participants from 25 countries to discuss the latest advances in a...

Strain Detail Sheet for STOCK <i>Cgas^tm1Ciphe</i>/Mmucd

Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…

YouTube video by GLOBAL IMMUNOTALKS

Subscribe to our YouTube channel to stay updated and participate in the discussions: https://www.youtube.com/c/GLOBALIMMUNOTALKS We now offer: ✅ Live streaming on YouTube (in addition to Zoom) ✅ Asyn...

Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…

The innate immune receptor cGAS is geared toward detecting DNA from pathogens. In a recent Cell publication, Lahaye et al. discovered that viral infection triggers de novo synthesis of self-DNA-activa...

Cell Research - Centromeres as minefields: host–virus warfare

Herpesvirus proteins disrupt centromeres, triggering centromeric DNA amplification and local nuclear activation of the nucleic acid sensor cGAS. This reveals an immune surveillance mechanism in the nu...

EJI and EFIS are thrilled to announce a new prize honoring Early Career Researchers (ECRs) whose work is published in EJI. This initiative aims to showcase the next generation of immunologists and encourage them to submit their excellent research to EJI.

Phagocytosed bacteria can serve as an alternative nutrient source for macrophages, influencing their metabolic and immune responses through the recycling of microbial components, with the process regu...

52m 11.30.24

Hervé, Scelfo et al. show that chromosome mis-segregation induces mTORC2- and ATR-mediated p53 activation through a mechanosensitive checkpoint at the nuclear envelope triggered by altered heterochrom...