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Vindigni Lab

@vindignilab.bsky.social
411 followers 201 following 10 posts

Washington University in St. Louis vindignilab.wustl.edu

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Vindigni Lab @vindignilab.bsky.social · 19/08/2025
Congratulations @seppai99.bsky.social for defending her thesis last week!!! Such an honor having her in the lab and excited about the next steps in her career!!!
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Stand Up for Science! @standupforscience.net · 29/06/2025
The proposed budget slashes NIH by ~40%, devastating medical research, clinical trials, treatment breakthroughs—life-saving work. Thousands of lives at risk for tax cuts for the rich? NO THANKS. Tell your senators to oppose the cuts HERE: zurl.co/qiKdX zurl.co/RCR0y #CutsCostLives
zurl.co
Will the Senate Save NIH?
Rescuing biomedical research is every bit as important as saving Medicaid.
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AyalaLab @ayalalab.bsky.social · 29/06/2025
Call your legislators to stop slashing the budget of federal funded research in the “Big Beautiful Bill”. Find numbers @5calls.org
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Vindigni Lab @vindignilab.bsky.social · 08/05/2025
Congratulations Isabelle for winning the Future of Science Fund at the Keystone!! We are very honored to have such a fantastic student in the lab!!!
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Keystone Symposia @keystonesymposia.bsky.social · 30/04/2025
Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and @seppai99.bsky.social! Your achievements inspire us. 🌟 #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
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Alberto Ciccia @albertociccia.bsky.social · 17/04/2025
Happy to share our DNA Repair special issue on the replication stress response curated with @vindignilab.bsky.social. www.sciencedirect.com/special-issu...
sciencedirect.com
DNA Repair | The replication stress response: mechanisms and functions | ScienceDirect.com by ElsevierScienceDirect
High-fidelity DNA replication is constantly challenged by a diverse range of obstacles, including endogenous lesions and secondary structures in the DNA template, tightly bound protein-DNA complexes, ...
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Petr Cejka @cejkalab.bsky.social · 26/03/2025
An interesting collaboration with the @vindignilab.bsky.social on the mechanism of resection at gaps. Spoiler alert: the MRE11 complex acts very differently at gaps vs. at DNA breaks genesdev.cshlp.org/content/earl...
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Vindigni Lab @vindignilab.bsky.social · 26/03/2025
Check out our new paper led by @seppai99.bsky.social from the Vindigni Lab in collaboration with @cejkalab.bsky.social delving into the role of nucleases resecting ssDNA gaps generated by PARPi. You can read more here: genesdev.cshlp.org/content/earl...
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Lopes_Lab @lopeslab.bsky.social · 17/03/2025
Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇
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AyalaLab @ayalalab.bsky.social · 23/02/2025
www.washingtonpost.com/science/2025...
washingtonpost.com
Scientists warn of long-term damage as Trump’s orders slow research
By blocking announcements in the Federal Register, the administration is keeping experts from meeting to evaluate funding proposals.
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 22/02/2025
this is breaking through keep up the full court press * patients harmed right now * hurts our economy right now * destroys our STEM infrastructure * gift to global competitors and adversaries * dirty tricks by bureaucrats who failed HS chemistry twice
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 22/02/2025
a great way of framing the issue — the bureaucrats are scheming to wreck science they can’t criticize or understand👇🏽 “This really feels like an evil way of using bureaucracy against the process of science, to the contrary of what they say they are doing — streamlining bureaucracy,” Cooper said.
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Keith Bellizzi, PhD, MPH @drkeithbellizzi.bsky.social · 20/02/2025
Federal Register Blackout Blocks NIH Funding www.medpagetoday.com/special-repo... The White House found a loophole around the judge’s orders to lift the freeze that will cripple research and scientific discovery for years.
medpagetoday.com
Federal Register Blackout Blocks NIH Funding
New strategy is like pouring 'cement in the pipes of the federal funding infrastructure'
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Jeremy Berg @jeremymberg.bsky.social · 19/02/2025
Very important to get this word out!
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Jeffrey Dean @jeffdean-uga.bsky.social · 18/02/2025
Trump Cuts Target Next Generation of Scientists and Public Health Leaders www.nytimes.com/2025/02/18/u...
nytimes.com
Trump Cuts Target Next Generation of Scientists and Public Health Leaders
A core group of so-called disease detectives, who track outbreaks, was apparently spared. But other young researchers are out of jobs.
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AyalaLab @ayalalab.bsky.social · 11/02/2025
www.washingtonpost.com/science/2025...
washingtonpost.com
Trump’s NIH challenges the model that underlies U.S. scientific dominance
The 80-year-old partnership between the federal government and research institutions has made the U.S. the leader in scientific innovation. But now a proposed funding cut threatens the arrangement.
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Nicolas Robine 🇪🇺🇫🇷🇺🇸 @nicorobine.bsky.social · 10/02/2025
Petition to Reverse the NIH Indirect Cost Cap. Sign and Circulate. Mobilize. Organize. chng.it/LS57Nk7r6k
chng.it
This campaign needs you now
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
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Sumedha Agashe @sumedhaagashe.bsky.social · 31/01/2025
Check out our (@vindignilab.bsky.social) Spotlight article highlighting @durocher1.bsky.social group's discovery of synthetic lethal SMARCAL1-FANCM interaction, revealing a novel genetic buffering mechanism for genome stability at simple repeat regions during replication www.cell.com/trends/genet...
cell.com
Genetic buffering mechanisms in SNF2-family translocases
SNF2-family DNA translocases, a large family of ATPases, have poorly defined roles in genomic stability. In a recent study, Feng et al. identified a synthetic lethal interaction between the SNF2 trans...
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Vindigni Lab @vindignilab.bsky.social · 26/11/2024
The Vindigni, Krais and @vermalab-washu.bsky.social Labsgiving 2024 featured a full turkey, many laughs and lots of multi-cultural food! 🦃
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Vindigni Lab @vindignilab.bsky.social · 22/11/2024
Finally got on the trend and moved to bluer skies! Though our lab photo got the memo long ago 🧬
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