Just returned from another wonderful EMBO meeting on "Telomere function and maintenance in health and disease" in Lazise by lake Garda. So great to reconnect with colleagues from the field and to make...

Very happy to have been selected to take part in the Pathways2 program as part of the UKRI's FLF development network. It was great to attend the recent community building event in Manchester, meeting...

DNA secondary structures, such as hairpins, cruciforms, triplexes, G-quadruplexes and iMotifs, are common, dynamic features that replication forks rou…

Garvin et al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive cellular SUMOylation. In...

Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is frequently misregulated in cancer...

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