The Munson Lab researches the mechanistic basis for the regulation of spatial and temporal specificity in membrane trafficking in the Biochemistry & Molecular Biotechnology Department at UMass Chan Me...

Septins are a family of GTP-binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. G...

Long-read sequencing, paralog-aware variant calling, and telomere-to-telomere (T2T) human genome assemblies now enable the resolution of copy-, haplotype-, and nucleotide-level complexities in segment...

The blast fungus forms a force-generating appressorium for plant infection. Eseola et al. show how individual spore cells adopt distinct fates, trafficking organelles to the appressorium or undergoing...

Molecular network; Molecular neuroscience; Cellular neuroscience

BY ADRIANA V. DIFRANCO What do fungi in the forest and human placentas have in common? It sounds like a riddle, but it’s actually a fascinating biological conundrum. Fungi and placentas have two of th...

Collection of endosomal protein protein interactions captured by cross-linking mass spectrometry and modeled via AlphaFold multimer.

Motor-driven transport on microtubules is critical for distributing organelles throughout the cell. Most commonly, organelle movement is mediated by cargo adaptors, proteins on the surface of an organ...

Using FPs fused with actin or its fiduciary probes Lifeact, Chromobody and Tractin, we studied, by time-resolved microscopy, the actin module of endocytosis in Aspergillus nidulans. F-actin probes eff...

This Review delves into the fungal kingdom, exploring the relationships among fungi, animals, plants and the environment, and investigating both the threats posed by fungi and their potential benefits...

The newly configured department marshals biochemists, biophysicists and experts in protein engineering and imaging to drive discoveries in the basic mechanisms of cell function.

The climate crisis is a multiscale problem that requires transdisciplinary expertise for understanding and engineering climate resilience. Cells are the first responders of the biosphere and yet cell…