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Soni Lacefield

@lacefieldlab.bsky.social
1.7K followers 1.6K following 71 posts

Cell biologist | Professor at Geisel School of Medicine at Dartmouth | interested in meiosis, mitosis, cell cycle checkpoints, chromosome segregation

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Reposted by Soni Lacefield
André Marques @amarques.bsky.social · 20/09/2026
This looks like an awesome review! Looking forward to reading it 🙌 congratulations @needhibhalla.bsky.social and @lacefieldlab.bsky.social
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Corentin Claeys Bouuaert @ccb-lab.bsky.social · 21/08/2026
Happy to see this paper published in Nucleic Acids Research! academic.oup.com/nar/article/...
academic.oup.com
Insights into the recruitment of the H3K4me3 reader Spp1 by the meiotic double-strand break protein Mer2
Abstract. The formation of DNA double-strand breaks (DSBs) by Spo11 is tied to the loop-axis organization of meiotic chromosomes. Before DSB formation, chr
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Soni Lacefield @lacefieldlab.bsky.social · 15/09/2026
I’m excited to share that my department is hiring at the full professor level!
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Soni Lacefield @lacefieldlab.bsky.social · 10/09/2026
I am excited to share our preprint on the meiotic role of Stu2 in error correction of kinetochore-microtubule attachments. We find a heightened requirement for kinetochore-associated Stu2 in meiosis. Work of grad student @batula.bsky.social! www.biorxiv.org/content/10.6...
biorxiv.org
Accurate chromosome segregation is more dependent on kinetochore-bound Stu2 in meiosis than mitosis
Accurate chromosome segregation requires bipolar kinetochore-microtubule attachments. Error correction mechanisms promote cycles of kinetochore-microtubule release and reattachment until bipolar attac...
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Reposted by Soni Lacefield
Drummond Lab @drummondlab.bsky.social · 08/09/2026
We are hiring! 🌟 Dept of Biochemistry and Molecular Biology at the University of Chicago is searching for a tenure-track assistant professor. It's a broad search: we want great colleagues doing serious biological work at the molecular scale. Join us! apply.interfolio.com/191981 bcmb.uchicago.edu
A picture of the University of Chicago campus, with downtown Chicago in the distance and Lake Michigan on the horizon. The campus's central quad is pictured, a classical collegiate quad with paths and old trees and stone architecture. It's really pretty and I love it.
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Hiten Madhani @hitenmadhani.bsky.social · 27/08/2026
Most basic science departments at UCSF are having faculty searches this year. Biochemistry & Biophysics, Microbiology & Immunology, Cellular and Molecular Pharmacology, Physiology and more. We're looking for new and exciting science and nice people. You'll find them all at aprecruit.ucsf.edu
aprecruit.ucsf.edu
Welcome - AP Recruit
University of California, San Francisco Online Faculty Recruitment
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Anthony Vecchiarelli @cellforganized.bsky.social · 26/08/2026
My MCDB Dept is hiring, again! Assistant Professor Faculty Search. Please Repost! Applications Due Oct 1st We welcome applications from all areas of cellular/molecular biology in prokaryotes, plants, and animals. More information can be found HERE: jobs.sciencecareers.org/job/679540/a...
jobs.sciencecareers.org
Assistant Professor - Ann Arbor, Michigan job with University of Michigan - Molecular, Cellular and Developmental Biology | 679540
UNIVERSITY OF MICHIGAN FACULTY POSITION IN CELL & MOLECULAR BIOLOGY AND RELATED FIELDS   The Department of Molecular, Cellular, and Developmental B...
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Soni Lacefield @lacefieldlab.bsky.social · 26/08/2026
Congrats to my colleague @jenelandino.bsky.social and lab members for paper of the year! www.ascb.org/society-news...
ascb.org
ASCB and MBoC Announce 2026 Paper of the Year Award Winners - ASCB
The American Society for Cell Biology (ASCB) and its research journal, Molecular Biology of the Cell (MBoC), are proud to recognize the outstanding scientific achievements of early career researchers ...
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American Society for Cell Biology @ascbiology.bsky.social · 25/08/2026
NIH is proposing changes to how grant scores are reported, replacing individual scores & percentiles with three broad categories. What could that mean for researchers deciding whether to revise and resubmit? Comments due Oct 13. www.ascb.org/science-policy/nih-cha…
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Reposted by Soni Lacefield
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 21/08/2026
Excited to have this out in the world! @lacefieldlab.bsky.social and I discuss meiotic checkpoints, with a focus on how they may be tuned both in and across systems to reflect the mechanistic trade-offs, evolutionary constraints and unique goals and innovations of meiosis. 🧪
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UC Berkeley MCB @berkeleymcb.bsky.social · 14/08/2026
MCB is hiring Assistant Professors across 3 divisions!: 🧪BBS: aprecruit.berkeley.edu/JPF05483 🧬GGED: aprecruit.berkeley.edu/JPF05481 🦠IMM: aprecruit.berkeley.edu/JPF05486 🗓️ Application Deadline: October 19, 2026 🔗 Click the links or scan the QR codes to learn more and apply
MCB is hiring 3 Assistant Professor positions across 3 divisions: 

Biochemistry, Biophysics and Structural Biology (BBS); Genetics, Genomics, Evolution, and Development (GGED); and Immunology and Molecular Medicine (IMM)

BBS application link: https://aprecruit.berkeley.edu/JPF05483

GGED application link: https://aprecruit.berkeley.edu/JPF05481

IMM application link: https://aprecruit.berkeley.edu/JPF05486
Assistant Professor of Immunology and Molecular Medicine (IMM). IMM application link: https://aprecruit.berkeley.edu/JPF05486Assistant Professor of Biochemistry, Biophysics and Structural Biology (BBS). BBS application link: https://aprecruit.berkeley.edu/JPF05483Assistant Professor of Genetics, Genomics, Evolution, and Development (GGED). GGED application link: https://aprecruit.berkeley.edu/JPF05481
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Soni Lacefield @lacefieldlab.bsky.social · 21/08/2026
Excited to share this review that @needhibhalla.bsky.social and I wrote on meiotic checkpoints! www.annualreviews.org/content/jour...
annualreviews.org
Tuning Meiotic Checkpoints: Evolutionary Costs and Mechanistic Trade-Offs
In this review, we discuss three meiotic checkpoints—the DNA damage response, the pachytene checkpoint, and the spindle checkpoint—and highlight their similarities and differences across diverse syste...
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Reposted by Soni Lacefield
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 27/07/2026
Beautiful work and modeling from the @lacefieldlab.bsky.social! #Meiosis4Eva
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Reposted by Soni Lacefield
Craig Kaplan @triggerloop.bsky.social · 08/07/2026
Update of my NIGMS funding estimates/data. Thanks to @needhibhalla.bsky.social for pointing to some FY2025 numbers showing funding rates. Funded grant # are from Reporter. FY2026 is in progress. A few points 1/
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Reposted by Soni Lacefield
Mark Peifer (He, him) @peiferlabunc.bsky.social · 06/07/2026
Check out the F99/K00 Predoctoral to Postdoctoral Transition Award, to support promising graduate students as they complete their doctoral research training and transition into mentored postdoctoral career development opportunities (please share) 1/n files.simpler.grants.gov/opportunitie...
files.simpler.grants.gov
PA-27-037: Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)
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Sally G Pasion @sgpombe.bsky.social · 17/06/2026
Congratulations to @lacefieldlab.bsky.social @mcbdartmouth.bsky.social #DartmouthGeiselSchoolOfMedicine presenting the #Yeast26 Ira Herskowitz Award Lecture highlighting the link between #meiosis and #autophagy @genetics-gsa.bsky.social
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Chenshu Liu @chenshuliu.bsky.social · 09/06/2026
I'm excited to co-organize this year's #Meiosis4Eva with @needhibhalla.bsky.social, @lacefieldlab.bsky.social, and @sadiewignall.bsky.social. We welcome submissions spanning chromosome dynamics, meiosis, evolutionary cell biology, and related areas of cell biology. See flyer for details!
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Reposted by Soni Lacefield
Erna Magnúsdóttir @e-rna.bsky.social · 04/06/2026
Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík! Apply here: tinyurl.com/mryvhdwj #epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
A full-time PhD position is available for application, focusing on research into molecular mechanisms and transcriptional regulation in embryonic stem cells and mouse primordial germ cells at the University of Iceland.

The project is funded by the Research Fund of the Science and Innovation Council and will be conducted at the Biomedical Center within the Faculty of Medicine at the University of Iceland, under the supervision of Erna Magnúsdóttir, Associate Professor at the Faculty of Medicine. The PhD student will also be affiliated with the Graduate Program in Life and Medical Sciences (GPMLS), which is a joint program involving all research groups in the life sciences at the University of Iceland.
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Pallavi Gadgil @pallavisgadgil.bsky.social · 20/05/2026
Thank you! Thank you @mcbdartmouth.bsky.social @lacefieldlab.bsky.social for this great opportunity!
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Soni Lacefield @lacefieldlab.bsky.social · 28/03/2026
I’m excited to share that our pic of meiotic midbodies in wildtype and mos mutant oocytes made the cover @jcellsci.bsky.social! Congrats to @muhammad-haseeb.bsky.social and @giselacairobaza.bsky.social!
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American Society for Virology @amersocvirology.bsky.social · 23/03/2026
ASV congratulates Dr. Felicia Goodrum, the 2026 Wolfgang and Patricia Joklik Distinguished Service Awardee. Thank you very much for your many years of service to ASV, Dr. Goodrum!
Picture of Dr. Felicia Goodrum, winner of the ASV Wolfgang and Patricia Joklik Distinguished Service Award.
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Soni Lacefield @lacefieldlab.bsky.social · 21/03/2026
www.worlddownsyndromeday.org Today we celebrate World Down Syndrome Day to appreciate the contributions and perspectives of people with Down Syndrome today and every day, while raising awareness for true inclusion.
worlddownsyndromeday.org
Home - World Down Syndrome Day
Did you know that 21st March is World Down Syndrome Day? Learn why this official day exists and what it is about.
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Soni Lacefield @lacefieldlab.bsky.social · 13/03/2026
Check out the first person interview!
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Soni Lacefield @lacefieldlab.bsky.social · 13/03/2026
So exciting to see this article in JCS! Thanks to the hard work from my lab members Gisela Cairo, MA Haseeb, Zach Boyce Joy, and great collaboration with Karen Schindler!
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Soni Lacefield @lacefieldlab.bsky.social · 23/02/2026
I am so honored to give the Ira Herskowitz Award lecture at #Yeast26! Please join us, it’s going to be a fantastic meeting! @genetics-gsa.bsky.social
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Soni Lacefield @lacefieldlab.bsky.social · 16/02/2026
Thanks for the highlight! Check out all of these awesome papers! More to come on ours….
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Soni Lacefield @lacefieldlab.bsky.social · 01/02/2026
Excited to join ASCB leadership as the chair of the Public Policy Committee. Science advocacy is so important right now and I am excited about the team we have to take on these efforts! www.ascb.org/about-ascb/l...
ascb.org
Leadership Directory - ASCB
ASCB’s mission is to lead a diverse, global and multidisciplinary scientific community focused on the cell, the basic unit of all life. Executive Committee Council Members Committee Chairs Editors In ...
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Reposted by Soni Lacefield
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 23/10/2025
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
nature.com
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
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Soni Lacefield @lacefieldlab.bsky.social · 11/10/2025
The Lacefield Lab won second place in the great pumpkin derby! @dartmouthbcb.bsky.social @mcbdartmouth.bsky.social
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Soni Lacefield @lacefieldlab.bsky.social · 10/10/2025
Lacefield Lab grad student @pallavisgadgil.bsky.social gave an excellent talk at Geisel’s Biomedical Research Day! Congratulations Pallavi! @dartmouthbcb.bsky.social @mcbdartmouth.bsky.social
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Soni Lacefield @lacefieldlab.bsky.social · 08/10/2025
Just a reminder about our faculty search at Dartmouth’s Geisel School of Medicine. Applications due Oct. 15. @dartmouthbcb.bsky.social
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American Society for Cell Biology @ascbiology.bsky.social · 29/09/2025
According to news reports, NIH is on track to award nearly all of its FY25 budget. Program officers—working long hours despite staff losses—made it possible. Take a moment to thank your PO for their dedication.
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Soni Lacefield @lacefieldlab.bsky.social · 29/09/2025
Congrats @moseleylab.bsky.social! @dartmouthbcb.bsky.social
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Soni Lacefield @lacefieldlab.bsky.social · 29/08/2025
Check out our new manuscript on biorxiv on the role of MOS in mammalian oocyte meiosis: www.biorxiv.org/cgi/content/... With @schindlerlab.bsky.social @giselacairobaza.bsky.social @muhammad-haseeb.bsky.social
biorxiv.org
A persistent intracellular bridge and cell cycle misregulation enable polar body cell divisions and tumor formation in Mos-deficient eggs
Mammalian female meiosis is uniquely regulated to produce a developmentally competent egg capable of supporting embryogenesis. During meiosis I, homologous chromosomes segregate, with half extruded in...
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Soni Lacefield @lacefieldlab.bsky.social · 27/08/2025
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438 @dartmouthbcb.bsky.social @futurepislack.bsky.social
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Brian Calvi @briancalvi.bsky.social · 15/08/2025
Flybase is free to use but not free to make. It takes large teams of people and millions of dollars a year to create the knowledgebas and tools for fly research. Please donate generously.
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Soni Lacefield @lacefieldlab.bsky.social · 15/08/2025
Just finished teaching another year of CSHL Yeast Genetics and Genomics with a fantastic group of students as usual! @cshlcourses.bsky.social
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American Society for Cell Biology @ascbiology.bsky.social · 07/08/2025
Meet the 14 scientists named 2025 ASCB Fellows! Honored for excellence in research, mentorship, and service, they’ll be recognized at Cell Bio 2025 this December in Philadelphia. Read more: www.ascb.org/society-news...
ascb.org
Fourteen Visionary Scientists Named 2025 ASCB Fellows - ASCB
The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to cell...
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Soni Lacefield @lacefieldlab.bsky.social · 17/07/2025
I have the privilege of working with these fantastic people every day! @mcbdartmouth.bsky.social @ Dartmouth Geisel School of Medicine!
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American Society for Cell Biology @ascbiology.bsky.social · 01/07/2025
The "Big Beautiful Bill" isn’t the federal budget—it’s a reconciliation bill focused on tax cuts. The real FY26 funding decisions for NIH, NSF, and more are happening now in Congress. www.ascb.org/science-poli...
ascb.org
The "Big Beautiful Bill" is Not the Budget - ASCB
If you’ve read recent news about Congress trying to pass “the budget,” you may have noticed that even Washington, D.C. reporters don’t always have a firm grasp on the details of what they’re covering....
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Mary Munson @marymunson4.bsky.social · 09/06/2025
Great to see such strong support for our courageous NIH colleagues, who are standing up for science!
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Soni Lacefield @lacefieldlab.bsky.social · 09/06/2025
Super excited to post our new publication on the role of MOS/MAPK signaling in maintaining the egg transcriptome. Great collaboration with Britt Goods lab! rep.bioscientifica.com/view/journal...
rep.bioscientifica.com
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Soni Lacefield @lacefieldlab.bsky.social · 05/06/2025
Scientists in GA, ASCB has scheduled a virtual Hill Day on June 25. We need scientists willing to talk to their representatives about the consequences of the proposed budget slashes. Please sign up. Or, send to colleagues. Just need to be or become ASCB members. www.ascb.org/ascb-meeting...
ascb.org
ASCB Georgia Virtual Capitol Hill Day
ASCB Virtual Hill Day with members of the Georgia Congressional delegation.
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Francesca Cole @francescacole.bsky.social · 26/04/2025
Wow - Sharon Dent is amazing - this is so great! Congratulations Sharon ❤️
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Soni Lacefield @lacefieldlab.bsky.social · 25/04/2025
Many congratulations to @pallavisgadgil.bsky.social for being awarded the Lucille Smith award for excellence in Biochemistry. This award is in honor of the memory of Dr. Lucille Smith. The first woman at Dartmouth to attain the rank of full professor!
Pallavi holding an award certificate.
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Soni Lacefield @lacefieldlab.bsky.social · 04/04/2025
Excited to post our new preprint on how MOS/MAPK signaling impacts the egg transcriptome! Great collaboration with Britt Goods and lab!
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Corentin Claeys Bouuaert @ccb-lab.bsky.social · 19/02/2025
🥳Just published @nature.com. Over 25 years after the discovery of SPO11 as the enzyme responsible for initiating meiotic recombination, we finally succeeded in reconstituting its DNA cleavage activity.🧵 www.nature.com/articles/s41...
nature.com
SPO11 dimers are sufficient to catalyse DNA double-strand breaks in vitro - Nature
A biochemical system recapitulates the hallmarks of meiotic double-strand break formation, with mouse SPO11 catalysing break formation in the absence of any partners and remaining covalently atta...
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Justin Kumar @flyeyelab.bsky.social · 29/03/2025
Super excited that my superstar friend Soni Lacefield @lacefieldlab.bsky.social is a AAAS fellow! See how her creative research is making an impact on our understanding of meiosis and infertility. geiselmed.dartmouth.edu/news/2025/so...
geiselmed.dartmouth.edu
Soni Lacefield Named a Fellow of the American Association for the Advancement of Science
Soni Lacefield, PhD, a professor of biochemistry and cell biology at Dartmouth’s Geisel School of Medicine, has been named a 2025 Fellow of the American Association for the Advancement of Science (…
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 28/03/2025
Congratulations to @lacefieldlab.bsky.social and all the other @aaas.org Fellows! 🥳 geiselmed.dartmouth.edu/news/2025/so...
geiselmed.dartmouth.edu
Soni Lacefield Named a Fellow of the American Association for the Advancement of Science
Soni Lacefield, PhD, a professor of biochemistry and cell biology at Dartmouth’s Geisel School of Medicine, has been named a 2025 Fellow of the American Association for the Advancement of Science (…
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Ele Willoughby @minouette.bsky.social · 20/03/2025
Happy birthday to Canadian medical researcher & #biochemist Maud Menten (1879-1960). 🧪🐡👩🏼‍🔬 #histscj Not only was she an author of Michaelis-Menten equation for enzyme kinetics, she invented the azo-dye coupling for alkaline phosphatase, 1st example of enzyme histochemistry, still used in imaging of 🧵
Linocut portrait of biochemist and medical researcher Maud Menten (1879-1960) with the Michalis-Menten equation in blue and a histology image in pinks and purples in the background.
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