In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...

Dense active materials, from cellular tissues to jammed and glassy systems, must continuously relieve internal mechanical stress to remain structurally stable as they are driven far from equilibrium. ...

“It can competently perform a lot of the work I need immediately,” this professor writes

In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...

Cells within biological tissue are constantly subjected to dynamic mechanical forces. Measuring the internal stress of tissues has proven crucial for our understanding of the role of mechanical forces...

This Review explores how cells sense and respond to mechanical signals across timescales. By integrating mechanosensing at membranes, mechanotransduction in the cytoplasm, and nuclear reprogramming, it reveals a role of temporal dynamics in tissue development and disease.

In 1985, experiments revealed the quantum behaviour of a macroscopic degree of freedom: the phase difference across a Josephson junction. The authors recount the history of this milestone for the development of superconducting quantum circuits.

Epithelia are intricate tissues whose function is intimately linked to mechanics. While mechanobiology has primarily focused on factors such as cell-generated contractility and mechanical properties o...

As railways enter their third century of service, research must support their renaissance for more-sustainable travel that supports human development.

Science isn’t really moving towards equity; institutions are just perfecting the appearance of equity. We need to build an alternative system.

These MATLAB scripts determine the nematic orientation field on the entire surface of 3D tissues of arbitrary shape, based on z-stack images, identify topological defects, and quantify signals of f...

Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is known to strongly alter macromolecule mobility, how cytop...

This Review discusses current 2D and 3D microscopy methods for imaging three-dimensional cell cultures and emerging strategies to address key challenges.

La compétition cellulaire est un mécanisme de surveillance essentiel qui élimine les cellules indésirables, jouant un rôle clé dans le développement, la répon