Patrick Shih cofounded Totality Biosciences to make human milk oligosaccharides for more-nutritious baby formula

It’s even weirder in some ways than the hexagon at its north pole

Transposable elements (TEs) are a highly diverse group of selfish genomic elements, prevalent across the tree of life, whose uncontrolled propagati...

Nine pioneering researchers have been announced as this years' recipients.

Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is foundational to life on Earth, catalyzing carbon dioxide (CO2) fixation to generate biomass. However, Rubisco is a slow and inefficient enz...

Rubisco catalyzes the primary CO2-fixing reaction of the biosphere, yet its competing oxygenation reaction reduces net global carbon fixation and has resisted direct exploration in living cells. Here,...

Rubisco has inherently low catalytic efficiency limiting crop productivity. Here the authors show that chloroplast genome editing can be used to generate substitutions in Arabidopsis rbcL that increas...

How membranes are integrated into biomolecular condensates is a fundamental question in cell biology. In the algal pyrenoid, an organelle responsible for one-third of global carbon fixation, CO2-deliv...

Algal photosynthesis relies on a biomolecular condensate known as the pyrenoid, which sequesters the cell’s Rubisco. The pyrenoid constituent Rubisco activase partitions to the condensate via an eleme...

Avi Flamholz leverages computational tools and microbial biochemistry to improve climate models and provide novel engineering solutions to address climate change.

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The yeast vacuole membrane forms ordered microdomains that facilitate microlipophagy under nutrient limitation. We previously found that this process …

How a discovery in the 1970s changed the theory of the origin of complex life on earth.

Maren Nattermann, Research Group Leader at the Max Planck Institute for Terrestrial Microbiology, on Marjory Stephenson (1885–1948): pioneer of chemical microbiology, whose work on bacterial metabolic...

In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...