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Thibaut Brunet

@thibautbrunet.bsky.social
5.8K followers 3K following 612 posts

Evolutionary cell biology / evolution of morphogenesis / animal origins / choanoflagellates @institutpasteur.bsky.social research.pasteur.fr/en/team/evoluti…

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Thibaut Brunet @thibautbrunet.bsky.social · 57m
Multicellularity journal club 📚📝
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Ina Sonnen @sonnenlab.bsky.social · 14h
🎉 Our paper is out today in @science.org! How does the intestine maintain the right balance of cell types? We find that signalling rhythms matter! So proud of our three shared first authors, Sonja Weterings, @hiromuneeto.bsky.social & @jddeleede.bsky.social! 🔗 www.science.org/doi/10.1126/...
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EMBO @embo.org · 07/10/2026
We spoke with four researchers who have repeatedly chosen Review Commons as a preprint #PeerReview platform for their own work. 🧪 Learn why they decided on Review Commons here: www.embo.org/features/why-i-chose-r… #LifeSciences #research #publishing #preprint
embo.org
Why I chose Review Commons – Features – EMBO
Four scientists shared their experience on the benefits of journal-agnostic peer review.
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Thibaut Brunet @thibautbrunet.bsky.social · 15/10/2026
besoin de sommeil
static.klipy.com
Donald Duck is sleepy in bed
ALT: Donald Duck is sleepy in bed
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Jean Léon Maître @maitrejl.bsky.social · 12/10/2026
Bloop 🫧 bloop 🫧 bloop 🫧 Fluid-filled lumens are everywhere in our body How do they get soooo big? We find that osmotic pressure vastly dominates mechanical forces in controlling lumen swelling in mouse embryos biorxiv.org/content/10.6... @louise-dagher.bsky.social @matteo-bassanini.bsky.social
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Iva Tolić @ivatolic.bsky.social · 09/10/2026
Very happy to see our work highlighted by @natcellbio.nature.com. A great team effort and a fascinating example of how a simple physical principle can connect mitosis across eukaryotes! @lgudlin.bsky.social, @krunovuk.bsky.social, @kopslab.bsky.social
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Thibaut Brunet @thibautbrunet.bsky.social · 11/10/2026
Oui
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paveltomancak.bsky.social @paveltomancak.bsky.social · 11/10/2026
Vive la France
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Evgenii Protasov @evgenii-protasov.bsky.social · 10/10/2026
The archaeon Sukunaarchaeum mirabile, associated with dinoflagellates, has a genome of only 238 kbp🧬🤯 #archaea #symbiosis #eukaryotes #protists #MicroSky @currentbiology.bsky.social www.cell.com/current-biol...
cell.com
A hidden archaeal lineage with an ultra-reduced genome retaining only its replicative core
Harada et al. describe an archaeon, recovered from a single marine plankton cell, whose 238-kb genome is the smallest known for the domain. It has lost nearly all metabolism but keeps the machinery to...
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Joshua G. Schraiber @jgschraiber.bsky.social · 11/10/2026
I'm not a software engineer but in my experience as a computational scientist, most individual parts of my job are basically automated. The thing that's not there (yet) is stringing them together in an interesting way. Then again I've never tried launching 10k agents at a problem!
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Thibaut Brunet @thibautbrunet.bsky.social · 10/10/2026
Terence Tao is great, but also, we don’t understand how paracetamol works (the same for: propofol, lithium for bipolar disorder…)
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Harmit Singh Malik @harmitmalik.bsky.social · 10/10/2026
Most animal species pack sperm DNA with protamines instead of histones. Protamines are essential for male fertility. They are among the fastest-evolving genes in animals. That makes little sense. We think we know why, in a new paper led by @ching-hochang.bsky.social. www.science.org/doi/10.1126/...
science.org
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Although essential for sperm function, protamines evolve rapidly for reasons that remain unknown. Using in vivo gene replac...
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Ewan Birney @ewanbirney.bsky.social · 10/10/2026
The @embl.org PhD programme closes in 48 hours - you still have time to rush in an application if you are a science, maths or computer science undergraduate wanting to do a PhD in one of the world's leading biology and AI institutes www.embl.org/about/info/e...
embl.org
Application – EMBL International PhD Programme
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Itai Yanai @itaiyanai.bsky.social · 10/10/2026
1. CRISPR came from basic research on bacteria. 2. Optogenetics started with a discovery in algae. 3. The GFP protein comes from jellyfish. The biggest breakthroughs all trace to scientists following their curiosity, and this is one huge reason why we must keep funding basic research!
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Thibaut Brunet @thibautbrunet.bsky.social · 10/10/2026
J’ai entendu cela aussi ! Sous une forme encore plus étrange : la Chine n’aurait *jamais dans son histoire* tenté de conquérir ses voisins (le Vietnam, la Corée, la Mongolie… ont tous fait l’objet de guerres de conquête répétées). J’imagine que plus c’est gros, plus ça passe.
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Kirsty Wan @micromotility.bsky.social · 09/10/2026
Please enjoy this new offering from the lab: we discover that #excavates - ancient flagellate lineages with a voracious appetite for bacteria - change their behaviour depending on the availability of said prey! Preprint here: www.biorxiv.org/content/10.6... #protistsonsky
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Christophe 🔬 Leterrier @christlet.bsky.social · 09/10/2026
Nikon Small World does the right thing
nikonsmallworld.com
Nikon Small World in Motion Video Statement | News | Nikon Small World
An update from Nikon Small World regarding the 2026 Small World in Motion first-place winning video: After thoroughly re-evaluating the video and supporting materials and consulting with members of…
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Thibaut Brunet @thibautbrunet.bsky.social · 09/10/2026
One never knows with Trump, but he seems to only know of the meaning of "artificial" as "fake" (antonym: "real"), and not really as "man-made" (antonym: "natural"). He thinks AI is "real" intelligence and thus not "artificial".
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Thibaut Brunet @thibautbrunet.bsky.social · 09/10/2026
The etymology of the color "sepia" is my new favorite etymology (h/t Wikipedia)
Wikipedia screenshot: Sepia is a reddish-brown color, named after the rich brown pigment derived from the ink sac of the common cuttlefish Sepia. The word sepia is the Latinized form of the Ancient Greek word σηπία (sēpía), meaning cuttlefish.
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Nicolas Berrod @nicolasberrod.bsky.social · 08/10/2026
Info Le Parisien : Kyan Khojandi est le nouveau parrain du Pasteurdon, qui vise 3 millions d'€ de dons cette année. "En tant que comique, je ne sauve pas des vies. Mais si je peux apporter un coup de projecteur à mon humble niveau, tant mieux !" 1/4 www.leparisien.fr/so...
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Thibaut Brunet @thibautbrunet.bsky.social · 09/10/2026
This kind of nuanced take addresses the concerns of both sides... which I hope/feel are anyway less polarized irl than on social media
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Thibaut Brunet @thibautbrunet.bsky.social · 09/10/2026
I found this proposal by @caseywdunn.bsky.social et al interesting: distinguishing LLMs "off the data path" (used to produce code one can verify/use; usually fine) vs "on the data path" (less verifiable, potentially problematic) www.cell.com/patterns/ful...
(A) The LLM lives off the data path: the assistant produces code that can be versioned and archived, and the code itself sits on the path.
(B) The LLM lives on the data path: the model call is itself a node, and reproducing the workflow requires the original runtime.
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The Company of Biologists @biologists.bsky.social · 09/10/2026
Applications close on 23 October for funded ECR places at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027 organised by Mauricio Rocha Martins @rocha-lab.bsky.social and Giulia Paci @giuliapaci.bsky.social Apply at biologists.com/workshops/ap...
Bridging Scales and Disciplines to Understand Robust Development
Date: 18-21 April 2027

Location: Buxted Park, East Sussex, UK

Organisers: Mauricio Rocha Martins and Giulia Paci
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Yasin Dagdas @plantophagy.bsky.social · 09/10/2026
European Union, Marie Curie, EMBO should triple postdoc fellowships! www.nature.com/articles/d41...
nature.com
US proposes $100,000 charge for international students to do post-graduate work
Proposed rule would choke off a crucial STEM talent pipeline, policy specialists say
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Michalis Averof @michalis-averof.bsky.social · 04/02/2026
Just discovered the wonderful covers of 'Genes to Cells', the journal of the Molecular Biology Society of Japan @mbsj-official.bsky.social – absolutely beautiful! here some examples inspired by mitosis, CRISPR, the DNA helix, and plant pigments
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Hanna Häkkinen @hannamariahakkinen.bsky.social · 09/10/2026
How do long-lived multipotent stem cells cope with mechanical stress in vivo? We found that neural crest cells are protected from mechanical stress during migration in confined tissue environment. www.nature.com/articles/s41...
nature.com
In vivo DNA damage protection during cell migration across confining embryonic tissue environments - Nature Cell Biology
Häkkinen et al. show that zebrafish neural crest cells encounter increased tissue-scale confinement along the body axis. Despite nuclear deformation, migrating neural crest cells experience neither nu...
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Thibaut Brunet @thibautbrunet.bsky.social · 09/10/2026
How fast can speciation be? In less than 100 years, certain strains of lab mice have already (partly) lost the ability to hybridize with each others. The molecular mechanism has just been worked out - read below for a genetics detective story ⬇️
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paveltomancak.bsky.social @paveltomancak.bsky.social · 09/10/2026
I think we really need what I provocatively would call the #AI-bro versus #luddite meeting in science soon. The viewpoints are diverging, and neither is tenable. There is a need to start looking for common ground for the benefit of science.
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Juliette Mathieu @jujumathieu.bsky.social · 09/10/2026
My favourite long neck choano found again in Mediterranean sea. Finger crossed to get it grow this time! 🤞 #protistsonsky
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Mill_lab @cilialab.bsky.social · 08/10/2026
Microscopy images are scientific evidence, and that image processing must be transparent and faithful to the underlying biology. Reinforce those standards, especially now-insist Nikon uphold them. #NikonSWiM2026 Read the letter: tinyurl.com/OpenLetterSW... Add your name: forms.gle/TyGRELnCxq5z...
tinyurl.com
Open letter to Nikon Small World in Motion
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Thibaut Brunet @thibautbrunet.bsky.social · 08/10/2026
Beautiful new review that breaks down a hard problem (evolution of complex multicellularity) into 4 easy steps. As a bonus, make sure to check out the great, didactic video summary
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Maël @mael.kont.me · 08/10/2026
Espérons que Berlin ait abandonné ses lobbyings puissants pour miner le nucléaire, la voiture electrique, etc dans l'optique de protéger son industrie thermique (gaz et pétrole) pendant que la Chine montre l'exemple.
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Benoit Ladoux @bladoux.bsky.social · 08/10/2026
🔬 We're hiring a Laboratory Manager! Join our growing international team at the Max Planck Center for Physics and Medicine in Erlangen! 🧬 Cell & molecular biology 🧪 Lab coordination & experimental research 📩 Apply now: [www.fau-jobs.de/jobposting/8173a980…]
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Marc Robinson-Rechavi @marcrr.ecoevo.social.ap.brid.gy · 07/10/2026
Cool work on slow evolving lineages, aka "living fossils". I like the contrast between the morphologically conserved lineages and control species-poor lineages. Sad not to see amphioxus included though. www.biorxiv.org/content/10.64898/20… #EvoDevo #Phylogenetics
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Pawel Burkhardt @pawelburkhardt.bsky.social · 07/10/2026
From bioRxiv to PNAS! 🎉 Very happy to see our paper “Diversity and spatial segregation of TRP channels in the closest relatives of animals” now published in @pnas.org. Another piece in the puzzle of how animal cell signalling evolved. www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Casey Dunn @caseywdunn.bsky.social · 06/10/2026
Our new paper in PLoS One on siphonophore genomes, with chromosome-scale genome for Nanomia septata! Led by @nahuja.bsky.social with @dalila-de.bsky.social, @shchurch.bsky.social, @dts.bsky.social and others. doi.org/10.1371/jour...
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Will Ratcliff @wcratcliff.bsky.social · 07/10/2026
Out today in @nature.com: our review on how single cells evolve into multicellular organisms. With Ozan Bozdag, @kaitong25.bsky.social, Peter Yunker, and @matthewherron.bsky.social. rdcu.be/9ZuiKow9twKa For an overview, check out the video below.
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Gaspar Jekely @jekely.biologists.social.ap.brid.gy · 07/10/2026
In our new paper by Kata Szabó et al. we present optimised sample-preparation workflows for volume electron microscopy for entire small marine organisms. The workflow includes high-pressure freezing, various freeze substitution protocols and synchrotron […] [Original post on biologists.social]
X-ray image of a platynereis annelid worm larva collected at the European Sycnrotron Facility at Grenoble. The left image shows morphological rendering of a 6-day-old Platynereis scanned at 100 nm/px, the right images show individual image planes of the same larva scanned at 55 nm/px or 20 nm/px.
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DEEMteam_Orsay @deemteam.bsky.social · 06/10/2026
How do redox conditions in an Asgard archaea-rich environment determine their vertical distribution? Find out in our latest paper about the amazing Catherine crater lake microbial mat: www.nature.com/articles/s41...
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Casey Dunn @caseywdunn.bsky.social · 06/10/2026
Our new tool corpus makes biodiversity literature searchable by AI agents via MCP, with provenance to source text and figures. With @shchurch.bsky.social , Felipe Zapata, and Maciej Mańko. In @currentbiology.bsky.social - www.cell.com/current-biol... Code: github.com/caseywdunn/c...
cell.com
Extracting AI agent-accessible data from biodiversity literature with corpus
Church et al. present corpus, a tool that converts a library of biodiversity literature PDFs into a searchable knowledge base of text, figures, and references. It connects to an AI agent through a Mod...
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Floris BOSVELD @florisbosveld.bsky.social · 06/10/2026
Check out our latest work on developmental scaling: collective cell migration speeds up in larger animals and slows down in smaller ones, helping maintain a constant pace of tissue morphogenesis across different-sized animals. @ybellaichelab.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
Tissue mechanics sets developmental scaling of collective cell migration
Despite substantial variation in adult size, animals within a species maintain consistent tissue patterns and shapes, a core property known as developmental scaling or size invariance. Developmental s...
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Jean Léon Maître @maitrejl.bsky.social · 06/10/2026
📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr
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Alex de Mendoza @alexdemendoza.bsky.social · 06/10/2026
It's live! The next @embo.org #EvoChromo meeting will take place next year October in St Feliu de Guíxols (Spain), check it out here: meetings.embo.org/event/27-chr.... It's been great to co-organise with @dodonova-sveta.bsky.social @kellervalsecchi.bsky.social @cedricfeschotte.bsky.social & Nick I.
meetings.embo.org
Chromatin evolution from molecules to genomes
Technological advances over the past decade have enabled genome-wide mapping of chromatin organization across diverse organisms at unprecedented resolution. These studies have uncovered both conserve…
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Alexis Lomakin, Ph.D. @alexis-lomakin.bsky.social · 06/10/2026
www.nature.com/articles/s41...
nature.com
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions - Nature Microbiology
Density-dependent regulation of collective order through collision sensing and collision-induced reversals provides a navigational advantage to Pseudomonas aeruginosa during surface colonization and n...
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Jean-Yves Tinevez @jytinevez.bsky.social · 05/10/2026
We have a position open in our core facility in the @pasteur.fr . Please share it and / or apply! forum.image.sc/t/research-e...
forum.image.sc
Research engineer in Bioimage Analysis. Institut Pasteur, Image Analysis Hub - 2026
Dear all Below is an announcement for a permanent position as a Research Engineer in the Institut Pasteur, Paris. There is a flyer attached at the bottom. We are looking ideally for a Bioimage An...
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Casey Dunn @caseywdunn.bsky.social · 05/10/2026
Interested in joining our lab (dunnlab.org) and YIBS as a postdoc? I'm looking for someone to work on siphonophores, diversity in the open ocean, or natural history. If that's you, please reach out this week to discuss a nomination for the Donnelley Postdoc Fellowship - yibs.yale.edu/donnelley-fe...
dunnlab.org
The Dunn Lab
Casey Dunn's laboratory in the Department of Ecology and Evolutionary Biology at Yale University.
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SBCF @sbcf.bsky.social · 05/10/2026
🔬 La SBCF vous invite à « Architectures Vivantes », une conférence grand public avec Manuel Théry (CEA), dans le cadre de #CellLaVie ! 📅 21 octobre, 19 h – 20 h 📍 Institut Pasteur, Paris 🎟️ Gratuit, inscription obligatoire avant le 14 octobre via le QR code de l’affiche.
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Javier del Campo @fonamental.bsky.social · 05/10/2026
Comparative analysis of mitochondrial proteomes across the tree of life #protists www.sciencedirect.com/science/arti...
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Thibaut Brunet @thibautbrunet.bsky.social · 05/10/2026
(more seriously, there’s been www.sciencedirect.com/science/arti... for example but I haven’t seen it used yet and I don’t know if it will be… in any case we didn’t patent it 😅)
sciencedirect.com
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