This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…

Wickström discovered how cells sense the physical world around them. Her research showed that cells can “feel” forces such as pressure and stretching and relay these signals all the way to their DNA. ...

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Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...

Summary: A guide to mechanics in development: unlock how forces, material properties and geometry shape the forms of life.

Epithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...

Within red blood cells, Plasmodium falciparum forms cells with multiple nuclei that replicate asynchronously despite residing in a shared cytoplasm. In this study, the authors developed a biophysical ...

Integrin adhesions allow dynamic cell-matrix interactions to regulate cell behaviour. Here, the authors reveal that tensin 1, a multidomain adaptor protein, forms condensates in cells that act as reve...

Cell adhesion enables animal multicellular development. E-cadherin and the cadherin-catenin adhesion complex at adherens junctions are engaged in dynamic interactions with actomyosin generated contrac...

Tissue resilience requires tight coupling between cell proliferation, growth, and death.1,2,3,4It is assumed to be based on compensatory proliferation…