Reposted by Wai-Hong ThamWEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 29/07/2026We’re excited to share researchers from WEHI and global biopharmaceutical company MSD have been named finalists in the 2026 Eureka Prizes for their teamwork that has led to a new class of antimalarial treatment candidates 👏👏 Read the story: www.wehi.edu.au/news/from-la... 021
Reposted by Wai-Hong ThamJoost Snijder @joostsnijder.bsky.social · 30/06/2026Very happy with this ERC Proof of Concept grant 😁. We get to test our new DENV prefusion stabilized E-dimers as immunogens. www.uu.nl/en/news/thre...uu.nlSecurity verifications 0151
Reposted by Wai-Hong ThamMelanie Bonhivers @mbonhivers.bsky.social · 12/06/2026The CNRS has opened a Junior Professor Chair (CPJ) call in Parasitology, and the Microbiologie Fondamentale et Pathogénicité (MFP, Bordeaux) laboratory is among the potential host institutions. More information: www.insb.cnrs.fr/fr/cnrsinfo/... #Parasitology #Protozoology #ResearchJobs #CNRSinsb.cnrs.frJunior Professor Chairs (CPJ) 2026 – CNRS BiologyCNRS Biology is recruiting researchers through its Junior Professor Chair (CPJ) program, subject to final approval by the French Ministry of Higher Ed 1813
Wai-Hong Tham @thamlab.bsky.social · 25/05/2026Nanobodies against malaria parasite adhesins that block receptor engagement and invasion Lovely work by @jaisondsa.bsky.social and Jill Chmielewski on PfRh5, PfRh4 & PvRBP2b nanobodies + stabilized PfRh4 🦙🩸⛰️ Have a read, share widely and please give us feedback! www.biorxiv.org/content/10.6... 071
Reposted by Wai-Hong ThamMadhu Pai, MD, PhD @madhupai.bsky.social · 22/05/2026A year before he passed away, I interviewed Dr Paul Farmer @pih.org about his book on Ebola So relevant right now, especially the dangers of “control-over-care approach” - i.e. isolation & quarantine, but fails to ensure adequate clinical care to the sick www.forbes.com/sites/madhuk...forbes.comEbola, Covid-19 And The Elusive Quest For Global Health EquityPublished during this pandemic, Paul Farmer’s new book, “Fevers, Feuds, And Diamonds,” is important, as it presents a critical dissection of the Ebola outbreak in West Africa, and the lessons we can l... 24314
Reposted by Wai-Hong ThamBritish Society for Parasitology @bspparasitology.bsky.social · 12/05/2026We’re excited to welcome Lina Pinto-García @linapintogarcia.bsky.social as our special guest speaker to discuss her recent book, Maraña: War and Disease in the Jungles of Colombia. Time: Thursday 28.05.2026 , 3 PM BST Location: Zoom (Link available after registration) forms.gle/cVADyb6F5Dmh... 254
Reposted by Wai-Hong ThamJonathan Pruneda @jnpruneda.bsky.social · 28/04/2026Registration has been reopened to fill the last few remaining spots! Last chance to join us in Leiden this June! 043
Reposted by Wai-Hong ThamReuters Legal @legal.reuters.com · 27/04/2026Eli Lilly said on Monday it would buy privately held blood cancer treatment developer Ajax Therapeutics for up to $2.3 billion in cash.reut.rsEli Lilly to buy Ajax Therapeutics for up to $2.3 billionEli Lilly said on Monday it would buy privately held blood cancer treatment developer Ajax Therapeutics for up to $2.3 billion in cash. 022
Reposted by Wai-Hong ThamMadhu Pai, MD, PhD @madhupai.bsky.social · 24/04/2026“Women today make up nearly a third of the global research workforce. But workforce representation does not automatically translate into senior or leadership positions” theconversation.com/women-in-sci...theconversation.comWomen in science – global study finds presence without powerWomen make up one in three researchers worldwide, but they remain sidelined in scientific organisations. 02513
Reposted by Wai-Hong ThamMichelle Wille @duckswabber.bsky.social · 23/04/2026How does HPAI affect different animals? Here airway organoids from ten diverse wildlife + livestock. host-specific differences in infection rate + patho. Useful for receptor-binding, viral dynamics, early host adaptation in poorly characterized animals 👉 www.tandfonline.com/doi/full/10.... 163
Reposted by Wai-Hong ThamSylvie Callegari @sylviecallegari.bsky.social · 23/04/2026Glycogen is ubiquitinated in vivo! And there is a clever method to detect it. It had been a privilege seeing this story come together by my colleagues in the @komanderlab.bsky.social. This will no doubt have important implications for metabolism. 071
Reposted by Wai-Hong ThamMarco Jochem @marcojochem.bsky.social · 23/04/2026Interested in non-proteinaceous ubiquitination, induced proximity or glycogen? Then you should have a look at our newest article, “Ubiquitination of glycogen and metabolites in cells and tissues”, just published in Nature: www.nature.com/articles/s41... 55331
Reposted by Wai-Hong ThamKelvin Lau @klausenhauser on 🙅♂️🐘🪡 @klausenhauser.bsky.social · 22/04/2026Calling all xray structure folks that have worked with denovo proteins. Do you suffer from high rfactors? Myself, someone else I know and now multiple structures all seem to suffer from this. Assuming we all tried our best in model building, what could be some causes? 51512
Reposted by Wai-Hong ThamBiochemical Society @biochemsoc.bsky.social · 14/04/2026A huge congratulations to César de la Fuente who receives the Biochemical Society Award for Significant Breakthrough or Achievement for his pioneering research into AI-driven antibiotic discovery! With AMR an increasing threat, Cesar's work paves the way for new treatments. 073
Reposted by Wai-Hong ThamBiochemical Society @biochemsoc.bsky.social · 14/04/2026Congratulations to Tom Deegan who receives the Colworth Medal in 2027! Pioneering work from the Deegan Lab has redefined our understanding of eukaryotic DNA replication and provided conceptual and technical frameworks that continue to drive new discoveries across molecular biology. 2198
Reposted by Wai-Hong ThamMegan Sloan @sloanmegan.bsky.social · 07/04/2026We open with @sheinerlab.bsky.social introducing a scientist who needs no introduction - Dominique Soldati-Favre. Dominique was awarded lifetime membership to the @bspparasitology.bsky.social for her immeasurable contributions to the field. #bsp #parasites #peoplemakeglasgow 0145
Reposted by Wai-Hong ThamJan-Hannes Schaefer @jhschaef.bsky.social · 07/04/2026We identified the maltoside detergent DM as an effective and easy solution to address preferred orientation in cryo-EM. Helped me switch from graphene grids. Special congrats to Maria Rafiq! @landerlab.bsky.social @nanigrotjahn.bsky.social @wisemanlab.bsky.social #cryoEM doi.org/10.64898/202... 35424
Reposted by Wai-Hong ThamJoost Snijder @joostsnijder.bsky.social · 30/03/2026Host cell remodeling via cyclin dependent kinases drives Ebola virus replication and transcription. www.biorxiv.org/content/10.6... Check out our latest preprint. Great work by @tshamorkina.bsky.social. Thanks to co-authors Danni Snikkers and @hecklab.bsky.social 1239
Reposted by Wai-Hong ThamScience Magazine @science.org · 19/03/2026Wild rice is a perennial, creeping plant. The secret to its perennial growth habit lies in a developmental reversal directed by small RNAs. This image illustrates how combining perennial genes with prostrate growth genes allows cultivated rice to mimic wild rice. Learn more: scim.ag/40GOjDb 08136
Reposted by Wai-Hong ThamEmily Furlong @emfurlong.bsky.social · 17/03/2026Very excited that the first publication from my lab is now online! Thanks to @actacrystd.iucr.org editors and reviewers for the smooth publication process. And congratulations to first author, Jiayi Pan, who completed this work in her Master’s year! @biologyanu.bsky.social 4279
Reposted by Wai-Hong ThamRichard Sever @richardsever.bsky.social · 12/03/2026"bioRxiv is exactly the type of living experiment we all should be striving for, to achieve our shared goals of optimizing how research evidence is shared and used.” via @chrisnsimms.bsky.social www.nature.com/articles/d41...nature.comHow bioRxiv changed the way biologists share ideas – in numbersFour million articles are now downloaded from bioRxiv every month, according to an analysis of the life-science preprint server’s first 13 years of existence. 14513
Reposted by Wai-Hong ThamDaniel Hurdiss @danielhurdiss.bsky.social · 11/03/2026Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor doi.org/10.1038/s415...doi.orgStructures of Marburgvirus glycoprotein and its complex with NPC1 receptor - NatureMarburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus glycoprotein, accompanied by fusion-relevant rearrangements... 0178
Reposted by Wai-Hong ThamJoost Snijder @joostsnijder.bsky.social · 11/03/2026These HTA proteases from archaea work great for mass spec-based antibody sequencing. Paper out now in final form at Cell Systems. Congrats to @tshamorkina.bsky.social @tkadava.bsky.social @lperezpaneda.bsky.social and @hecklab.bsky.social www.sciencedirect.com/science/arti... 12414
Wai-Hong Tham @thamlab.bsky.social · 10/03/2026Congratulations to @jaisondsa.bsky.social who was awarded the JBC Herbert Tabor Early Career Investigator award from @asbmb.bsky.social 🎉 Awarded for Jaison’s PhD work on stabilized PvRBP2b variants using computational design for a better P. Vivax serological biomarker @wehi-research.bsky.social 051
Reposted by Wai-Hong ThamProf Brendan Crabb AC @brendancrabb.bsky.social · 08/03/2026Health and medical research is the only hope for so many health conditions, yet is chronically underfunded. Amazingly, a big part of the solution already exists. The money is literally in the bank, earmarked for health & medical research. It just has to be released. www.abc.net.au/news/2026-03...abc.net.auUp to $1.4 billion in medical research remains unused under government capResearchers say securing funding has become increasingly tough, with many left with no choice but to spend a disproportionate amount of time applying for grants. 33115
Reposted by Wai-Hong ThamLesley A Hall @erinacean.bsky.social · 08/03/2026IWD: somehow her name is less familiar, and yet, she actually received the Nobel: Dorothy Crowfoot Hodgkin: en.wikipedia.org/wiki/Dorothy...en.wikipedia.orgDorothy Hodgkin - Wikipedia 316044
Reposted by Wai-Hong ThamWomen in Malaria @womeninmalaria.bsky.social · 08/03/2026Happy International Women’s Day #IWD2026 🤩🎉 To celebrate the day we present the first WiM sketch of the year, featuring Dr Katharine Collins, the co-inventor of the R21 malaria vaccine 👩🏻🔬💉 172
Reposted by Wai-Hong ThamMatt Higgins @parasitematt.bsky.social · 03/03/2026Introducing our new blood-stage malaria vaccine immunogen based on the essential invasion protein PfCyRPA. By understanding where on PfCyRPA the best antibodies bind, we used structure guided design to generate PfCyRPA-EM, which contains only the epitopes of the best antibodies. 1158
Reposted by Wai-Hong ThamBloom lab @jbloomlab.bsky.social · 25/02/2026In new study led by Brendan Larsen, we map functional constraint across the Nipah virus F protein to define constrained epitopes for antibody targeting and identify mutations that stabilize the prefusion conformation for vaccine immunogens. www.pnas.org/doi/10.1073/...pnas.orgFunctional and antigenic constraints on the Nipah virus fusion protein | PNASNipah virus is a highly pathogenic virus in the family Paramyxoviridae that utilizes two distinct surface glycoproteins to infect cells. The recept... 12711
Reposted by Wai-Hong ThamDiego del Alamo @delalamo.xyz · 25/02/2026We're hiring - looking for folks with experience designing and training foundation models from scratch, particularly biomolecular language models, GNNs, or vision models. Lots of room for creativity in this role. Contact me if you have any interestjobs.takeda.comResearch Senior Scientist AI/ML Foundational Models at Takeda PharmaceuticalLearn more about applying for Research Senior Scientist AI/ML Foundational Models at Takeda Pharmaceutical 0114
Reposted by Wai-Hong ThamRichard Sever @richardsever.bsky.social · 24/02/2026Pretty reasonable summary of the state of COVID origin debate: what most experts think (zoonosis), where information is missing (some virology lab activities), what's clearly nonsense (cold chain), what's unsupported (deliberately made) www.nature.com/articles/d41...nature.comCOVID’s origins: what we do and don’t knowResearchers summarize key insights from the world’s first comprehensive investigation into how a pandemic started. 34516
Reposted by Wai-Hong ThamTom McLean @tommclean.bsky.social · 25/02/2026Come do a PhD with me and @trevor-lithgow.bsky.social at @monashuniversity.bsky.social ! We’re at the leading edge of pathogen biology using cutting edge Cryo-EM and AI-driven genetic screens to uncover the mysteries of outer membrane biology. Reach out to me for a chat! macsys.org/phd-scholars...macsys.orgPhD Scholarship at Monash University - MACSYSDo cutting-edge research at the intersection of cryo‑EM, genome-wide profiling, and AI-driven modelling. Work with world‑class cryo-EM/cryo-ET imaging and AI tools to discover how the dangerous bacter... 02118
Reposted by Wai-Hong ThamAndrew Burgess @drandrewburgess.bsky.social · 25/02/2026Do you or do you know someone impacted by bacterial #StrepA ? We are looking to hear from you! Use the QR code (or link) to register your interest in our Consumer Workshop to Help Shape the Future of a Breakthrough Vaccine to Eliminate Childhood Strep A Diseases. forms.office.com/r/7wjTxedG5G 121
Reposted by Wai-Hong ThamKristian G. Andersen @kgandersen.bsky.social · 24/02/2026In 2025, GISAID cut off access to many critical SARS-CoV-2 resources, incl. our outbreak.info. A month ago, GISAID leveled accusations against us, Cov-Spectrum, Nextstrain, and members of COG-UK, which are false and misrepresent known facts. Our joint response: blog.outbreak.info/joint-respon... 25731
Reposted by Wai-Hong ThamARC Tracker @arc-tracker.bsky.social · 25/02/2026The ARC have said (on LinkedIn) they will release outcomes for Discovery Projects Expressions of Interest (2027) tomorrow👇 13620
Reposted by Wai-Hong ThamWEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 19/02/2026We’re proud to welcome Prof Laura Mackay as our first Sir Gustav Nossal Professor of Immunology – advancing Sir Gus’ remarkable legacy, thanks to the generosity and vision of the Nossal family. More: www.wehi.edu.au/news/world-r... 0142
Reposted by Wai-Hong ThamANU Research School of Biology @biologyanu.bsky.social · 18/02/2026Join us on campus & online on Friday, 6 March 2026 at 1pm for a seminar by Kate O'Hara, PhD Candidate from the Moritz Group! Details: rb.gy/u9aqza 032
Reposted by Wai-Hong ThamCharles Bayly-Jones @charlesbj.bsky.social · 18/02/2026I’ve officially started my lab at Monash University! 🎉 We’re diving into #cellgrowth and #lysosome biology, through the lens of molecular #structure and mechanism. I’m thrilled to say that PhD student scholarships are available—so please share widely and get in touch if you’re interested. 🤩 43616
Reposted by Wai-Hong Thamsturalph.bsky.social @sturalph.bsky.social · 18/02/2026Some lovely work on the Plasmodium fertilisation machinery at #lorneiandi presented by Melanie Dietrich from the Tham Lab @thamlab.bsky.social - 1102
Reposted by Wai-Hong ThamVictorian Infection and Immunity Network @theviin.bsky.social · 18/02/2026Great to hear from Dr Melanie Dietrich from @thamlab.bsky.social @wehi-research.bsky.social. They found the native cryo-EM structure of Pfs230-Pfs48/45 complex, and identified domain 13 and 14 of Pfs230 as leading malaria transmission blocking vaccine candidates! 🦟 💉#lorneiandi 1101
Reposted by Wai-Hong ThamSjors Scheres @sjorsscheres.bsky.social · 16/02/2026Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...mrc.tal.netResearch Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research CouncilLocation: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55 184106
Reposted by Wai-Hong ThamProfessor Euan Ritchie FAMS @euanritchie.bsky.social · 16/02/2026Our son, Rohan, is smiling in this photo, but make no mistake, he worked so hard to reach his goal of 100km. @scidocmartin.bsky.social & I couldn't be prouder. www.theage.com.au/national/vic... There's still time to support his fundraiser for mental health 👉 www.mycause.com.au/page/385454/...theage.com.au‘He smashed it’: Teen marks 18th birthday with 100km run for charity‘I will not be going out partying’: teen runs nine hours straight to raise funds for charity. 910020
Reposted by Wai-Hong ThamOlivier Neyrolles @oneyrolles.bsky.social · 13/02/2026🎉 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐩𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐓𝐡𝐞 𝐄𝐌𝐁𝐎 𝐉𝐨𝐮𝐫𝐧𝐚𝐥! After 8 months of revision, our work is now online: shorturl.at/WHmFq We uncover a previously unrecognized way that 𝑀𝑦𝑐𝑜𝑏𝑎𝑐𝑡𝑒𝑟𝑖𝑢𝑚 𝑡𝑢𝑏𝑒𝑟𝑐𝑢𝑙𝑜𝑠𝑖𝑠 survives toxic metal stress during infection. ...shorturl.atMembrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis - The EMBO JournalBacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a prev... 13120
Reposted by Wai-Hong ThamTom Churcher @thomaschurcher.bsky.social · 12/02/2026Generous international scolarships for our MSc in Epidemiology here in London. In memory of Bob May. My career is 100% resulting from something similar to this *cough* *cough* 25 *cough*.....years ago! www.imperial.ac.uk/study/fees-a...imperial.ac.ukSearch our scholarshipsSearch scholarship opportunities. 032
Reposted by Wai-Hong ThamSylvie Callegari @sylviecallegari.bsky.social · 11/02/2026I'm hiring! If you are a structural biology postdoc with strong cryo-EM experience who is excited about mitochondrial membrane complexes, please apply! WEHI is a great place to work with access to state-of-the art cryo-EM facilities. Apply here 👇 wehi.wd3.myworkdayjobs.com/broadbean_ex...wehi.wd3.myworkdayjobs.comResearch OfficerJob Title Research Officer Job Description An excellent opportunity is available for a Research Officer/Senior Research Officer to join the Callegari Lab in the Ubiquitin Signalling Division at Austra... 094
Reposted by Wai-Hong ThamVictorian Infection and Immunity Network @theviin.bsky.social · 09/02/2026It's not too late to join us for Lorne I&I 2026! We have an incredible line-up of stellar Invited Speakers joining us from interstate and across the globe; check out our live Program for more details. Don't miss out, register now! www.lorneinfectionimmunity.org/registration #lorneiandi 083
Reposted by Wai-Hong ThamLorraine Reese @lorraine-reese.bsky.social · 06/02/2026Internationally renowned as one of the leaders in neurotransmitter transport research, don't miss Professor Renae Ryan (@renaeryan.bsky.social) present her #BiochemSoc International Award Lecture at Membrane #Proteins Conference 2026! 🧪 095
Reposted by Wai-Hong ThamNichollas Scott @nickescott.bsky.social · 05/02/2026Really happy to see this work out! Super fun project with a great team. For me the highlight was that we finally were able to show the O-linked glycosylation systems of H. pylori/C. jejuni are general glycosylation systems which target non-flagellin proteins (suggest >10 years ago by click chem). 2106
Reposted by Wai-Hong ThamDave Baltrus 🦦 @surtlab.bsky.social · 05/02/2026Been on multiple search committees For me (personally so YMMV)…I basically dismiss everything that’s labeled *submitted* unless there’s a preprint I can read 115917
Reposted by Wai-Hong ThamAngie Rasmussen @angierasmussen.bsky.social · 06/02/2026Have I ever mentioned how surreal it is to be an Editor-in-Chief of a journal called Vaccine right now? www.science.org/content/arti... It’s pretty wild, at least by typical academic journal editorial office standards.science.orgControversial Danish vaccine research group faces new allegationsResearchers say they couldn’t find complete data for 10 trials that together enrolled tens of thousands of children in Guinea-Bissau 1134088