SynthIDBio watermarks AI-generated protein sequences and structures while preserving function, enabling provenance detection and offering a proof-of-concept tool for biosecurity and information integr...

Pathogens target and degrade the extracellular matrix surrounding plant cells. A central question is how cell wall-derived damage-associated molecular patterns (DAMPs) are recognized and integrated to...

Popular vendors’ catalogs feature more than 18,000 manipulated images

In this post, we share two results that show how Claude can help life scientists increase the pace of their research. In the first, we tested Claude’s ability to design protein binders from scratch, a key step in creating protein-based drugs that has historically taken a specialist weeks or months per target. In the second example, we evaluated whether Claude can accelerate chemical analysis. Claude Opus 5, a generally available model, was given NMR and LC-MS data (the data that allows chemists to assess the identity and purity of the compounds they work with).

A detailed forecast and recommendation for how the US, China and the rest of the world should navigate superintelligence.

Deformable Neural Radiance Fields creates free-viewpoint portraits (nerfies) from casually captured videos.

Defense-associated reverse transcriptases (DRTs) are widespread bacterial anti-phage systems that use unconventional mechanisms of polynucleotide synthesis. We show that DRT3, which comprises two dist...

Design a protein capable of neutralizing the Nipah virus, a pathogen with up to 75% mortality rate and high pandemic potential, currently lacking effective treatments.

Ranawat et al. show the cryo-EM structures of Asgard archaeal chromatin assemblies, revealing that the histone HHoB assembles into both compact closed and extended open hypernucleosomes. The closed co...