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Elisa Fadda

@elisafadda.bsky.social
2.9K followers 1.7K following 2.2K posts

Associate Professor in the School of Biological Sciences at the University of Southampton, head chef at GlycoShape.org, Salem's butler, fucose fanatic #glycotime everyday! She/Her

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Reposted by Elisa Fadda
Stu Cantrill @stuartcantrill.com · 01/10/2026
One for #ChemSky 👇
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David K Smith @professor-dave.bsky.social · 30/09/2026
One of the most interesting biographies I discovered during my #DecolonisingChemistry project for the @chemistryatyork.bsky.social curriculum was that of Alice Ball a black chemist, whose leprosy treatment, using carbonyl chemistry to build on traditional medicine, was stolen by a male colleague.
Portrait of Alice Ball including images of the Chaulmoogra plant and its conversion into a leprosy treatment.
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Peter Coles 🏳️‍🌈 🏳️‍⚧️ 🇮🇪 @telescoper.bsky.social · 30/09/2026
Solidarity to all staff at Nottingham University on strike today and tomorrow www.ucu.org.uk/article/1466...
ucu.org.uk
University of Nottingham staff to strike for two months from October in redundancy fight
Staff at the University of Nottingham will strike on Wednesday 30 September and Thursday 1 October, and then solid strike action from 5th October until 11 December in a row over jobs and course cuts, ...
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Marcin Czerwinski @czerwinsmarcin.bsky.social · 21/09/2026
How to study glycosylation using bioorthogonal glycan-based tools: now in one comprehensive review. Highly recommended! tinyurl.com/27z2rhvv #glycotime
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Beilstein-Institut @beilstein-institut.bsky.social · 30/09/2026
Mark your calendars! 🧪 Join our free online #BeilsteinTalk "Targeting the sialic acid axis to enhance immune responses to cancer," with James Paulson of The Scripps Research Institute. 📅 Oct 8, 2026 🕔 5–6 pm CEST 🔗 tinyurl.com/4m834mzp #glycobiology #glycotime #CancerBiology #BeilsteinTalks
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Stu Cantrill @stuartcantrill.com · 30/09/2026
One week today, let's see if I (kinda) go 2 for 2 on #chemnobel...
A screenshot of my Bluesky post about the ChemNobel last year, that reads: 

#NobelPrize week starts tomorrow & the #chemnobel is Wednesday… used to be so much Nobel chat on Tw*tter, but that is not replicated here, alas. Anyway, for the record, I think MOFs will win at some point (maybe this year maybe not). Balasubramanian & Klenerman a good bet for next-gen sequencing too

Post was published 18:37 on Oct 5th
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Zack Polanski @zackpolanski.bsky.social · 29/09/2026
Why is the Government going after pensioners? It's time to tax the rich
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Caroline Lucas @carolinelucas.bsky.social · 29/09/2026
So let’s see practical steps to rejoin asap. As global insecurity grows, anything less simply won’t do
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The Francis Crick Institute @crick.ac.uk · 29/09/2026
We're looking for undergraduate students at UK universities who are interested in scientific research to join one of our labs or facilities for 12 months as part of our sandwich student programme. Apply by 6 October: www.crick.ac.uk/careers-and-study/s…
crick.ac.uk
Sandwich students
Sandwich students join one of the Crick’s research groups or science technology platforms for 12 months to work on a research project.
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Caroline Lucas @carolinelucas.bsky.social · 29/09/2026
Sadly there was a climate & nature shaped hole at the heart of Burnham’s speech. Nothing on the benefits of nature restoration & same old words on a “pragmatic” approach to N Sea drilling. There’s nothing pragmatic about pouring fuel on a scorching earth - he should rule out Rosebank & Jackdaw now
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Peter Coles 🏳️‍🌈 🏳️‍⚧️ 🇮🇪 @telescoper.bsky.social · 28/09/2026
There is no such thing as "AI upskilling"
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 28/09/2026
Ironically, here is Chi Pi’s mission statement: “To Build Better Men. Our members commit themselves to upholding Chi Phi’s values and practicing global citizenship. Chi Phi men are leaders, scholars, innovators, and gentlemen.” chiphi.org/who-is-chi-p...
chiphi.org
Chi Phi Fraternity | Who Is Chi Phi?
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Ben Schulz @benschulz.bsky.social · 28/09/2026
You know what will happen if you tell the plagiarising parrot your secrets
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Igor Brodsky @brodskyigorlab.bsky.social · 27/09/2026
The power of funding fundamental discovery in driving unexpected benefits for humankind are unmatched. We should be funding more basic research not less
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UCSF @ucsanfrancisco.bsky.social · 26/09/2026
UCSF’s Kevan Shokat, PhD, just won the $1M Stephenson Global Prize for research in pancreatic cancer. He cracked KRAS, a cancer driver long considered “undruggable.” Drugs built on his work now treat lung and pancreatic cancer. ow.ly/UYuY50ZRSXg
Middle-aged man in a blue lab coat smiling while seated in a scientific laboratory setting.Hand wearing black glove holding five small glass vials with various colored liquids, including pink and orange hues.
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Elisa Fadda @elisafadda.bsky.social · 27/09/2026
If you are a UK citizen/resident concerned about the environmental impact of data centers (we are talking about 340 hectares on UNESCO biosphere land here) please consider signing the petition: petition.parliament.uk/petitions/77... www.theguardian.com/uk-news/2026...
theguardian.com
‘People are standing up and fighting back’: the north Devon revolt against a vast AI datacentre
Plans for one of Europe’s largest AI campuses in a Unesco-designated reserve have sparked a fierce local backlash
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Os Keyes @okeyes.bsky.social · 15/09/2026
The result: national govts, think tanks and universities refocusing AI evaluations to focus on highly speculative problems where there is no empirical evidence that they're possible - but lots of ideological reason to take them seriously, whatever the costs of the very REAL issues we then ignore .
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 26/09/2026
On the importance of human judgement and ethical decision making. Two critical goals of university STEM education. www.aps.org/apsnews/2026...
aps.org
September 1983: Soviet officer defies military protocol, averting potential nuclear war
The American Physical Society is a nonprofit membership organization working to advance physics by fostering a vibrant, inclusive, and global community dedicated to science and society.
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Olivia Guest · Ολίβια Γκεστ @olivia.science · 26/09/2026
Please sign if you can! OPEN LETTER: PAUSE THE NATIONAL ROLLOUT OF AI-MEDIATED TUTORING IN ENGLAND'S SCHOOLS > Children should not be exposed to a technology whose future, effectiveness, and safety we cannot predict, and for which the evidence is mostly negative.
docs.google.com
OPEN LETTER: PAUSE THE NATIONAL ROLLOUT OF AI-MEDIATED TUTORING IN ENGLAND'S SCHOOLS
OPEN LETTER To the Rt Hon Andy Burnham MP, Prime Minister, and the Rt Hon Lucy Powell MP, Secretary of State for Education The Department for Education has announced plans to develop, what it calls, “...
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ChimeraX @chimerax.ucsf.edu · 25/09/2026
Make natural language requests to ChimeraX with the new Pellaeon plugin developed by Yam Amir that works with many free and paid large language models. Get Pellaeon using ChimeraX menu Tools / More Tools.... cxtoolshed.rbvi.ucsf.edu/apps/chimera...
PAR1 molecular structure shown in ChimeraX using Pellaeon chat bot.
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Craig Kaplan @triggerloop.bsky.social · 25/09/2026
Cryo-EM peeps are living the dream www.science.org/doi/10.1126/...
science.org
In-cell structures visualize human pre-ribosome assembly in the nucleolus
In eukaryotes, ribosome biogenesis initiates within the nucleolus, a hallmark multilayered compartment of the nucleus. Structures of pre-ribosomes have been characterized ex situ, but their assembly p...
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 26/09/2026
Bullshit, and shame on @science.org for this tie-in to an agitprop engine for the freaks in the AI "safety" movement. Super gross look for the magazine.
Our work is supported by a variety of foundations, charities, and individuals who share our commitment to high-quality journalism about AI (grouped by lifetime giving):

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$100K – $1M
The Amdur Family Fund (2026)
The Casey & Family Foundation (2025, 2026)
EA Infrastructure Fund (2023)
Future of Life Institute (2024, 2025)
Ought (2026)
$10K – $100K
ACX Grants (2024)
AI Safety Tactical Opportunities Fund (2024)
Cullen O'Keefe (2025)
Hazel Browne (2024)
Julia Wise and Jeff Kaufman (2026)
Mark and Jessica Zitter (2026)
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For details on donations, please see our .

We have also received donations of less than $10,000 from a variety of generous individual donors.

Our donors have no editorial control over the work of Tarbell, our fellows, or our grantees. Tarbell does not accept anonymous donations greater than $10,000. For details, see the Donor relations section of our .
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GlycoShape @glycoshape.org · 25/09/2026
Refreshed ReGlyco Filter in bioRxiv 🧪(doi.org/10.64898/202...) in view of the upcoming Protein Design Competition on Monday 28/09 🎉🔥 proteinbase.com/competitions... Each week a new target and if it's a glycoprotein, glycoshape.org and ReGlyco Filter can help screen and optimise your binder design
NiV G was the target of the Adaptyv Bio Protein Design Competition 2025. Structure of the Nipah Virus Glycoprotein (NiV-G) homotetramer (aa 92-602) reconstructed from cryo-EM structures (PDB 7TXZ and 7TY0) bound to broadly neutralising antibody nAH1.3 Fabs(Wang et al. 2022) (not shown). Static (single) glycans 3D structures (shown with sticks in blue) were reconstructed with GlycoShape ReGlyco(Ives et al. 2024). The glycoform selection was guided by glycoproteomics analysis(Hawkins et al. 2025). The visible six glycan sites on chains A, B and D are mapped onto the structure, while glycans on chain C are not labelled for clarity
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Andrew Coogan @cooganlab.bsky.social · 25/09/2026
Useless, absolutely useless. Or maybe I really should have Rong feelings on the matter?
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Rasmus Jensen @rasmusjensen.bsky.social · 25/09/2026
🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET
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Elisa Fadda @elisafadda.bsky.social · 25/09/2026
Got a glycoprotein as a target for your binder design competition on Monday? Look no further ⬇️ we got you 😎 #glycotime 🧪🔥
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Andrew Coogan @cooganlab.bsky.social · 25/09/2026
An admission of continuing failure. www.irishtimes.com/ireland/educ...
irishtimes.com
Irish colleges should focus on teaching abroad, not attracting foreign students – Minister
State already has insufficient accommodation for those in higher education, James Lawless says
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Diversity in Horror (they/them) @diversityhorror.bsky.social · 24/09/2026
A photo of a gray cat in front of a pink pie chart. On the top it says “Things that bring me joy.” The pie chart is divided into five sections that say: Going home to my cat, thinking about my cat, watching my cat enjoy a treat, rotting in bed with my cat, and talking about my cat.
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Derek Lowe @dereklowe.bsky.social · 24/09/2026
Thoughts on Anthropic’s worries about people accessing Claude for possible bioweapons design:
science.org
AI Help for Biological or Chemical Weapons
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Philip Ball @philipcball.bsky.social · 24/09/2026
This paper calling for more theory in biology makes some interesting points, but I'm left wondering where such theory is supposed to come from. Neither of the cases adduced - Darwin and Schrödinger - really corresponds to a theory in the usual sense. /1 elifesciences.org/articles/112...
elifesciences.org
Philosophy of Biology: The power of theory in the life sciences
Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 24/09/2026
Always great to see a paper on BioRxiv that reaches the same conclusions, using similar lines of evidence, to a paper that we put on BioRxiv 7 months ago and published in PNAS a month before theirs was posted — but doesn't cite our work. Here's our paper.
pnas.org
β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments | PNAS
PilC/PilY1 proteins are tip-located adhesins of type IV pili (T4P) that are critical for T4P function in diverse behaviors including twitching moti...
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Biological Sciences @sotonbiosciences.bsky.social · 24/09/2026
Dr Tomislav Cernava is part of IMPULSA, a new £2.5m ARIA-funded project exploring how plant immunity and the microbiome can help produce more disease-resistant oak trees in increasingly challenging environmental conditions. www.southampton.ac.uk/research/gro...
Acorns on an oak tree
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 24/09/2026
“Many of the greatest scientific breakthroughs have emerged from this ability to…challenge prevailing conceptual frameworks…it remains unclear whether [AI systems] can deliberately perform this kind of conceptual reframing.” www.nature.com/articles/s41...
nature.com
Scientific culture in the age of AI - Nature Cell Biology
Recent changes in Genentech’s scientific organization, occurring as the company makes artificial intelligence (AI) increasingly central to its research strategy, highlight a broader question facing bi...
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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 24/09/2026
AlphaFold Database is expanding into pandemic preparedness. Together with NVIDIA, DeepMind, EBI et al. we exhaustively predicted ~1.7 million homo- & heterodimers across 2,812 viral proteomes, resulting in 8,028 high-confidence predictions. 📄 research.nvidia.com/labs/dbr/ass... 🌐 alphafold.ebi.ac.uk
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Nature Communications @natcomms.nature.com · 22/09/2026
Co-authors @merylhaas.bsky.social, @danielhurdiss.bsky.social from @utrechtvirology.bsky.social and others show that the norovirus  NS3 protein forms an RNA-engaging molecular motor that may transport viral RNA during infection. #Virology #CryoEM dlvr.it/TVbP01
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Federica Genovese @fgenovese.bsky.social · 23/09/2026
Today is another excellent day to make a donation of sorts to the Royal National Lifeboat Institution.
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Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 22/09/2026
Use reward-guided search in a generative model's latent space to design high-affinity protein binders to proteins and carbohydrates. @karstenkreis.bsky.social @pierceogden.bsky.social www.biorxiv.org/content/10.6...
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 22/09/2026
This. So much this! "These advances make it tempting to equate experimental cataloguing and accurate prediction with the growth of our theoretical understanding of biological processes – an equivalence we believe is ultimately misleading."
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Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social · 10/07/2026
I posted a talk on youtube that I gave at Nantes Université last month: Structural Bioinformatics & AlphaFold Modeling of the Human Kinome & Its Interactions Covers our ipSAE score, active kinase structures, domain assignments to all 480 human kinases & interactomes. www.youtube.com/watch?v=o1s1...
youtube.com
Structural Bioinformatics & AlphaFold Modeling of the Human Kinome & Its Interactions. R. Dunbrack
YouTube video by Roland Dunbrack
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Libby Spencer @libbyspencer.bsky.social · 21/09/2026
Once down to a single pair. Conservationists rescued them from oblivion. The flock is now 350 strong. New Zealand’s karure, or black robin, has been crowned the country’s 2026 Bird of the Year. cnn.it/4rqzZeL
photo of the black robin.
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ABC News Australia @news.abc.net.au · 22/09/2026
Smart glasses to be banned in all WA public schools
abc.net.au
Smart glasses to be banned from WA public schools
Western Australia's education minister announces smart glasses will be banned from all state schools.
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Yuan He @yuanhejhu.bsky.social · 22/09/2026
A big week for the lab! Two new papers on how cells repair DNA double-strand breaks: one on getting NHEJ started in chromatin, one on processing the ends before ligation. Years of work by a fantastic team.
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Federica Genovese @fgenovese.bsky.social · 22/09/2026
Salvini, Meloni, Vannacci: “we will disenfranchise education, immigrant kids will be segregated, the curriculum will double down on traditional Italian culture (and btw no extra euro to schools)” President Mattarella at Amatrice <taps mic>
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Guardian US @us.theguardian.com · 21/09/2026
The current El Niño is likely to be the largest in at least 1,000 years and will pile extra heat into an atmosphere in which temperatures are already rising rapidly due to human-caused global heating. This double whammy means 2027 is expected to become the hottest year ever recorded.
theguardian.com
‘Jaw-dropping’ El Niño bursts through temperature record months before peak
‘Godzilla-level’ phenomenon is supercharging the climate crisis and will have a huge impact on communities across the world
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Guardian US @us.theguardian.com · 21/09/2026
The “jaw-dropping” El Niño currently heating up the planet has burst through the highest temperature ever recorded for the phenomenon, several months before its expected peak.
A line chart showing temperature anomalies in the Niño 3.4 region of the Pacific Ocean, compared to a 30-year rolling base period since 1982.

A gold line shows temperatures in 1997, a teal line in 2025, and a red line in 2026. The red line surpasses all others reaching 3.07ºC, and at an earlier point (September) than the previous El Niño that reached a comparable range in November 2015.
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Elisa Fadda @elisafadda.bsky.social · 21/09/2026
Congrats Nick @nmriley.bsky.social !! 👏🏻👏🏻👏🏻😎🎉🎉
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Richard Sever @richardsever.bsky.social · 21/09/2026
"authors could not answer...even basic questions about the paper...difficult to see how they could have verified the paper’s contents" medium.com/@TmlrOrg/ask...
medium.com
Asking Authors About Their Own Papers
By Nihar B. Shah
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Elisa Fadda @elisafadda.bsky.social · 21/09/2026
He's got nunchuk skillz 😎
static.klipy.com
Napoleon Dynamite Says 'Sweet!'
ALT: Napoleon Dynamite Says 'Sweet!'
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Martin Pacesa @martinpacesa.bsky.social · 21/09/2026
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi...
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Joe Bak-Coleman @jbakcoleman.bsky.social · 20/09/2026
These problems can be remarkably complex relative to what we think of as human intelligence; classic example being slime molds and recreating efficient transit maps. Obviously this is before we get to eusocial insects and the complex clockwork of their societies. Simple rules, emergent function.
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