Porat et al. develop cell surface ATAC-See, discovering that mitochondrial DNA is a component of the mammalian cell surface. Cell surface DNA (csDNA) on primary human and murine B cells and monocytes is removed by the secreted nuclease DNASE1L3, and dysregulation of csDNA levels is associated with autoimmunity.

Porat et al. develop cell surface ATAC-See, discovering that mitochondrial DNA is a component of the mammalian cell surface. Cell surface DNA (csDNA) on primary human and murine B cells and monocytes ...

Porat et al. develop cell surface ATAC-See, discovering that mitochondrial DNA is a component of the mammalian cell surface. Cell surface DNA (csDNA) on primary human and murine B cells and monocytes ...

Porat et al. develop cell surface ATAC-See, discovering that mitochondrial DNA is a component of the mammalian cell surface. Cell surface DNA (csDNA) on primary human and murine B cells and monocytes ...

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The move, affecting about one-fifth of the National Science Foundation’s primary research budget, is the latest sign of how the White House is asserting more control over grants.

The move, affecting about one-fifth of the National Science Foundation’s primary research budget, is the latest sign of how the White House is asserting more control over grants.

BACH2 restrains activation of the fetal-haemoglobin-encoding γ-globin genes, while loss of BACH2 enhances NRF2 chromatin occupancy and promotes the formation of activation foci at the γ-globin genes.

An online platform removed 257 papers written or co-written by the University of Chicago’s Nicholas Polson after other academics raised questions.

The Life Sciences Departments in Harvard Faculty of Arts and Sciences seek to recruit a tenure-track professor whose research is at the interface of AI and life sciences, […]

Recent changes in Genentech’s scientific organization, occurring as the company makes artificial intelligence (AI) increasingly central to its research strategy, highlight a broader question facing bi...

TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.

Glycans impact every aspect of physiology. Despite the rapid increase in relevance and translational potential, there remains a lack of tools for studying glycosylation in vivo. Here, we present FlyMO...

Abstract. Coenzyme A is an essential cofactor synthesized from pantothenate, which carries activated acyl groups in cellular metabolic reactions. Coenzyme

Polly Fordyce is building a global engine for protein discovery—one that could help researchers harness AI to create new medicines, materials, and climate solutions.

View Projected Impact of the FY2027 Budget Cuts to the NIH and NSF