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Margot Riggi

@margotriggi.bsky.social
209 followers 147 following 2 posts

Molecular animation at MPI for Biochemistry, Germany

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Reposted by Margot Riggi
mdreimann.bsky.social @mdreimann.bsky.social · 19/06/2026
Super excited to share my first paper from my PhD in the @dodonova-sveta.bsky.social lab. We visualise how chromatin from archaeal cells is organised using cryo-ET and SPA. Big thanks to everyone involved in this project!
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Eva Karasmanis @evakarasmanis.bsky.social · 29/05/2026
New preprint alert! Ever wonder if cells can talk to each other? Tunneling nanotubes (TNTs) are tiny bridges between cells used to pass organelles, nucleic acids, proteins & even viruses but we've never seen inside them clearly. Until now! 👇🧵 biorxiv.org/content/10.64898/2026.05.27.728322v1
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Briggs Group @briggsgroup.bsky.social · 21/05/2026
COPII at the ERES in-situ from @dr-downes.bsky.social in the Zanetti lab @giuliazanetti.bsky.social: doi.org/10.1038/s415...
doi.org
In situ cryo-ET defines the ultrastructure of ER exit sites in human cells - Nature Cell Biology
Downes et al. use in situ cryo-electron tomography and super-resolution fluorescence microscopy to define ER exit site architecture in unperturbed human cells. They visualize ribosome-exclusion zones ...
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David Bhella @dbhella.bsky.social · 13/05/2026
Wow - this is just amazing. Hui Guo and colleagues from John Briggs’ lab use cryoEM helical reconstruction to discover how filamentous influenza virion assembly is directed by multiple conformations of M1 - explaining how NA is concentrated at the proximal pole. www.biorxiv.org/content/10.6...
biorxiv.org
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Roux Lab, Geneva @rouxlab.bsky.social · 12/05/2026
@mhakala.bsky.social shows that HRS forms bidimensional condensates onto endosomal membranes to flatten clathrin/ESCRT-0, an observation unexplained since the 2000s. Thx to Kukulski lab, @stefvass.bsky.social @colomlab.bsky.social @kaksonen.bsky.social @mishakudryashev.bsky.social rdcu.be/fihKk
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Veesler lab @veeslerlab.bsky.social · 28/04/2026
We summarize our findings in an animation made in partnership with @jiwasa.bsky.social detailing the process of coronavirus entry into cells 14/19
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Florian Jug @florianjug.bsky.social · 02/04/2026
We've spent the last year building something at @humantechnopole.bsky.social that we think is genuinely needed: #AI that works across biological scales and data modalities, not just within them. A thread on what we're doing, why, and who we're looking for. A 🧵... 1/9
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Gaia Pigino @gaiapigino.bsky.social · 09/02/2026
Proud and excited to share our work with the community! Helen @helenfoster.bsky.social Foster et al. study how #cilia axonemes are built. 👀 Don't miss the gorgeous and insightful movies by @margotriggi.bsky.social, they really show our discoveries in full action! www.biorxiv.org/content/10.6...
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Helen Foster @helenfoster.bsky.social · 06/02/2026
There was so much to unpack with this data, we teamed up with the marvellous @margotriggi.bsky.social to help explain what we think is going on. (Please also check out our model of central apparatus assembly here: www.biorxiv.org/content/10.6...)
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Helen Foster @helenfoster.bsky.social · 06/02/2026
Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!
biorxiv.org
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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 10/12/2025
🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.
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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 10/12/2025
We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)! GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging. Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations. 👉 www.unige.ch/genexm/
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Journal of Cell Science @jcellsci.bsky.social · 09/12/2025
Leanna Owen, Margot Riggi , David Drubin, Janet Iwasa and Yidi Sun use molecular animation to depict the full progression of CME in budding yeast, with an accompanying Cell Science at a Glance article and poster. journals.biologists.com/jcs/article/...
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Rosana Collepardo @rcollepardo.bsky.social · 05/12/2025
Our Science paper is out! Huge congratulations to @huabin-zhou.bsky.social, Mike Rosen, and the brilliant @janhuemar.bsky.social @juliamaristany.bsky.social and @kieran-russell.bsky.social from our group News: bit.ly/4avnkAr and bit.ly/3XBGVHS Great perspective by @vram142.bsky.social +K Zhang
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Margot Riggi @margotriggi.bsky.social · 03/12/2025
Lots of fun working on this project! Looking forward to see more and more animations published in the future!
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Janet Iwasa @jiwasa.bsky.social · 05/08/2025
I'm so honored to receive the 2025 Bruce Alberts Award for Excellence in Science Education. Thank you @ascbiology.bsky.social and I look forward to this year's annual ASCB meeting in Philly!
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Janet Iwasa @jiwasa.bsky.social · 02/07/2025
Check out this new review (with animations, natch) of mechanisms of licensing origins of DNA replication - a wonderful (and continuing!) collaboration with Bruce Stillman @cshlnews.bsky.social and John Diffley @crick.ac.uk! www.nature.com/articles/s41...
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Juan Martin Serrano @juanmartin-serrano.bsky.social · 27/06/2025
What a fantastic ESCRT meeting, the field is going strong and full of exciting science. Many thanks to @rouxlab.bsky.social @cellarchlab.com @jujumathieu.bsky.social @magromayor.bsky.social @majarad.bsky.social for organising such a a great event
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Julie Kiefer @julieckiefer.bsky.social · 05/06/2025
Listen to @jiwasa.bsky.social @learngenetics.bsky.social @uofubiochem.bsky.social and Tim Lee @nhmu.bsky.social @utah.edu on @scifri.bsky.social talk about the forms #SciComm can take - why, how, impact How 'Science Interpreters' Make Hidden Science Visible www.sciencefriday.com/articles/sci...
sciencefriday.com
How ‘Science Interpreters’ Make Hidden Science Visible
A cell animator and a museum designer tell us how they translate scientific findings into visual experiences.
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Jerelle Joseph @jerelleaj.bsky.social · 16/05/2025
Thanks to @natsmb.nature.com for interviewing on our work: “seeing biomolecular condensates with computation” www.nature.com/articles/s41...
nature.com
Jerelle Joseph: seeing biomolecular condensates with computation - Nature Structural & Molecular Biology
Jerelle Joseph is an assistant professor at the Department of Chemical and Biological Engineering and the Omenn–Darling Bioengineering Institute at Princeton University in New Jersey. We contacted Jer...
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RCSB Protein Data Bank @rcsbpdb.bsky.social · 15/05/2025
Paper Published: A new chapter for Molecule of the Month Read how @jiwasa.bsky.social has taken over as the series creator of stories about critically important biological macromolecules pubs.aip.org/aca/sdy...
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Yi-Wei Chang @yiweichang.bsky.social · 15/05/2025
...and big thanks to @jiwasa.bsky.social for making this amazing video to illustrate the strand-sliding mechanism!
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Janet Iwasa @jiwasa.bsky.social · 11/04/2025
Had a great time chatting with Flora Lichtman and Tim Lee @nhmu.bsky.social a couple of weekends ago here in SLC, and excited that our Science Friday @scifri.bsky.social piece will be airing today! www.sciencefriday.com/segments/sci...
sciencefriday.com
How ‘Science Interpreters’ Make Hidden Science Visible
A cell animator and a museum designer tell us how they translate scientific findings into visual experiences.
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Reposted by Margot Riggi
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 21/03/2025
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6
Credit: Margot Riggi (@margotriggi.bsky.social), Max-Planck Institute of Biochemistry (@mpibiochem.bsky.social)
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Sven Klumpe @svenklumpe.bsky.social · 05/03/2025
Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?
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Briggs Group @briggsgroup.bsky.social · 28/02/2025
Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @margotriggi.bsky.social
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Max Planck Institute of Biochemistry @mpibiochem.bsky.social · 26/02/2025
The @briggsgroup.bsky.social alongside teams from @uniheidelberg.bsky.social and @yalemicropath.bsky.social uncover elusive role of #HIV-1 component SP2. Detailed 3D views of viruses by #cryoEM show how SP2 helps the virus matrix to mature. ❕Read the paper @nature.com www.nature.com/articles/s41...
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