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Jerelle Joseph

@jerelleaj.bsky.social
556 followers 136 following 98 posts

Assistant Professor, Princeton University | biomolecular condensates + computer simulations | josephgroup.princeton.edu (she/her)

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Jerelle Joseph @jerelleaj.bsky.social · 11/09/2026
Postdoc Position at the Princeton Center for Complex Materials: apply.interfolio.com/193107
apply.interfolio.com
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Jerelle Joseph @jerelleaj.bsky.social · 08/09/2026
📣There is still time to nominate someone for a #BPS theory and computation subgroup award! See more details here: drive.google.com/file/d/17aUc...
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Jerelle Joseph @jerelleaj.bsky.social · 21/08/2026
Nice thread by Nate on his new paper!
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Jerelle Joseph @jerelleaj.bsky.social · 20/08/2026
Out now in #JACS work led by the talented @nathanieldhess.bsky.social on protein folding inside condensates!! pubs.acs.org/jacsat/artic...
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Jerelle Joseph @jerelleaj.bsky.social · 20/08/2026
Out now in #PRXLife “Roadmap for Condensates in Cell Biology” journals.aps.org/prxlife/abst... From our amazing discussions at #KITP last summer!
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Reposted by Jerelle Joseph
pilarcossio.bsky.social @pilarcossio.bsky.social · 07/08/2026
⚡ Time is running out! ⚡ The deadline for the @biophysicalsoc.bsky.social Theory & Computation Awards is Sept 15! 🧬💻 Recognizing outstanding research across: 🎓 Postdocs 🌱 Early Career 🚀 Mid-Career Nominate a student or colleague! 🧪✨ 👇 Details: www.biophysics.org/Awards-Fundi...
biophysics.org
Subgroup Awards - The Biophysical Society
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Jerelle Joseph @jerelleaj.bsky.social · 06/07/2026
Out now in #CurrentOpinioninStructuralBiology! Our perspective on progress toward linking single-molecule behavior and emergent condensate properties! Led by Pablo Garcia and @ananyac2000.bsky.social 🙂 www.sciencedirect.com/science/arti...
sciencedirect.com
Progress toward linking single-molecule behavior and condensate material properties
Biomolecular condensates exhibit distinct material properties that are intimately linked to their functions. A major open question is how the properti…
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Jerelle Joseph @jerelleaj.bsky.social · 04/06/2026
📣 We’re accepting nominations for “Rising Stars in Bioengineering” (self nominations welcomed)! Deadline: Jun 30th, 2026 forms.gle/mmdzutrPk1fd...
forms.gle
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Reposted by Jerelle Joseph
Princeton University @princeton.edu · 27/05/2026
Congrats to this year's Distinguished Teaching honorees Amir Ali Ahmadi (operations research and financial engineering); Jeff Dolven (English); @jerelleaj.bsky.social (chemical and biological engineering and bioengineering); and Emma Ljung (Princeton Writing Program): bit.ly/4ux2VlN
President Eisgruber with Emma Ljung, Jeff Dolven and Jerelle Joseph.
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Reposted by Jerelle Joseph
Princeton University @princeton.edu · 15/05/2026
Four faculty members will receive 2026 Graduate Mentoring Awards for their exceptional guidance of graduate students: Edward Baring, Tom Griffiths (@cocoscilab.bsky.social), Jerelle Joseph (@jerelleaj.bsky.social) and Jamie Rankin: bit.ly/4dmoXQR Congratulations!
princeton.edu
Four faculty members recognized for outstanding mentoring of graduate students
This year's honorees are Edward Baring, professor of history and human values; Tom Griffiths, professor of psychology and computer science; Jerelle Joseph, assistant professor of chemical and biologic...
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Jerelle Joseph @jerelleaj.bsky.social · 13/04/2026
Massive congratulations to all new NSF GRFP awardees! Proud of our group alumni, Ian, Paul and Dhyey who were all successful!! 🥳🥳🥳🥳. Also hats off to everyone who applied regardless of the outcome 🙌🏽
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Jerelle Joseph @jerelleaj.bsky.social · 05/03/2026
Congratulations to Virginia Jiang, who is co-advised by José Avalos and me on winning a Student Research Achievement Award from #BPS!! 🥳🥳 www.eurekalert.org/news-release...
eurekalert.org
Biophysical Society selects Student Research Achievement Award winners
BETHESDA, MD – The 35 winners of the annual Student Research Achievement Awards (SRAA) were recognized at the 70th Biophysical Society Annual Meeting Awards Ceremony on February 23, 2025. These ...
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Jerelle Joseph @jerelleaj.bsky.social · 24/02/2026
On the cover of #JCP, Pablo’s work on “Condensate Deborah Numbers” pubs.aip.org/aip/jcp/arti...
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Jerelle Joseph @jerelleaj.bsky.social · 22/02/2026
The first four PhD candidates in the group are all at #BPS this week!! @nathanieldhess.bsky.social @ananyac2000.bsky.social Virginia Jiang and Pablo Garcia! Check out their talks and posters!! 👇🏽
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Jerelle Joseph @jerelleaj.bsky.social · 13/02/2026
Pablo’s work on “condensate Deborah numbers” is now out in #JCP!! Selected as Editor’s Pick and featured as a #Scilight pubs.aip.org/aip/jcp/arti...
pubs.aip.org
Molecular origins of viscoelasticity in biomolecular condensates
Biomolecular condensates are membraneless organelles that compartmentalize functions in living cells. Formed by the phase separation of biomolecules, condensate
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Jerelle Joseph @jerelleaj.bsky.social · 07/02/2026
Many condensates can be described as active soft materials that generate molecular fluxes. Here we develop a new #nonequilibrium approach (TRACE) to study molecular transport through condensates! Work led by Yashraj Wani!! www.biorxiv.org/content/10.6...
biorxiv.org
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Jerelle Joseph @jerelleaj.bsky.social · 14/01/2026
How does protein folding change inside biomolecular condensates? Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social
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Jerelle Joseph @jerelleaj.bsky.social · 11/01/2026
Out on the #bioRxiv in collaboration with @luciastrader.bsky.social, we probe the molecular basis for thermoresponsive condensation in plants! Work led by Sunita Pathak and @ananyac2000.bsky.social 🥳🥳 www.biorxiv.org/content/10.6...
biorxiv.org
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Jerelle Joseph @jerelleaj.bsky.social · 09/01/2026
Seriously some of the most fun I’ve had in this field so far! 🥳🥳 #kitp #roadmap #condensates
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Jerelle Joseph @jerelleaj.bsky.social · 05/12/2025
Want to learn about how we use computational approaches at different scales to study biomolecular condensates? Check out our latest review, out in Advances in Physics X @juliamaristany.bsky.social @alinaemelianova.bsky.social @rcollepardo.bsky.social www.tandfonline.com/doi/epdf/10....
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Jerelle Joseph @jerelleaj.bsky.social · 05/12/2025
Gave my last lecture yesterday. Started celebrating that, for the first time, I managed an entire semester without getting sick. Started feeling sick today 🤒…had a solid run though 😅
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Jerelle Joseph @jerelleaj.bsky.social · 21/11/2025
On the cover of #SoftMatter! Our work on condensate microstructure. Cover designed by Daniel Tan☺️ pubs.rsc.org/en/content/a...
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Jerelle Joseph @jerelleaj.bsky.social · 11/11/2025
Have not fully stopped but definitely way less now than before 💔
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Reposted by Jerelle Joseph
David Kuster @rnadavid.bsky.social · 09/10/2025
Very insightful reconsideration what Stress Granules might actually be good for! Going back to the fundamentals & questions arising from Susan Lindquist's and Nancy Kedersha's work. Amazing talk & scholarship by @drummondlab.bsky.social! youtu.be/caAPToh8v0Q
youtu.be
Physical Properties of the Cytoplasm Seminar Series #25 | Allan Drummond
YouTube video by Physical Properties of the Cytoplasm
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Jerelle Joseph @jerelleaj.bsky.social · 08/10/2025
Is there a way to directly connect microstructural dynamics of condensates to their mechanical response? In his new pre-print, Pablo presents a “condensate Deborah number” that does just that! www.biorxiv.org/content/10.1...
biorxiv.org
Biomolecular condensate viscoelasticity is dictated by the interplay between single-molecule shape memory and mesh reconfigurability
Biomolecular condensates are membraneless organelles that compartmentalize biological functions in living cells. Formed by the phase separation of biomolecules, condensates possess a wide range of mec...
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Jerelle Joseph @jerelleaj.bsky.social · 30/09/2025
Out now in #ACSMacroLett: we demonstrate how molecular charge asymmetry can control the size of condensates! Work done in collaboration with @zwickergroup.bsky.social!! Theory led by Chengjie Luo and simulations by @nathanieldhess.bsky.social!! pubs.acs.org/doi/10.1021/...
pubs.acs.org
Theory of Condensate Size Control by Molecular Charge Asymmetry
Biomolecular condensates are complex droplets comprising diverse molecules that interact by various mechanisms. Condensation is often driven by short-range attraction, but net charges can also mediate...
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Jerelle Joseph @jerelleaj.bsky.social · 23/09/2025
Out now in #SoftMatter, our work on linking single molecule features, microstructure, and macroscopic properties of condensates! Led by Daniel Tan, a former undergrad student who is now pursuing a PhD in Computational biophysics, Dilimulati Aierken and Pablo Garcia! pubs.rsc.org/en/content/a...
pubs.rsc.org
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Jerelle Joseph @jerelleaj.bsky.social · 15/09/2025
Now out in #ProteinScience! Work led by the talented 🥳🥳@ananyac2000.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Accurate prediction of thermoresponsive phase behavior of disordered proteins
Under heat stress, proteins have been shown to organize into biomolecular condensates in living cells. Recent experiments suggest that this response may be encoded in the chemical makeup of proteins....
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Jerelle Joseph @jerelleaj.bsky.social · 03/09/2025
Who else gets nervous for the first lecture of the semester? It doesn’t matter how many times you’ve taught the course?!!! 😩#fallsemester
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Jerelle Joseph @jerelleaj.bsky.social · 28/07/2025
On the cover of JACS Au! @alinaemelianova.bsky.social’s work with Pablo and Daniel on using atomistic and residue-resolution coarse-grained simulation to probe interactions between small molecules and biomolecular condensates!! Cover designed by D. Aierken w/ Alina! 1/
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Jerelle Joseph @jerelleaj.bsky.social · 14/07/2025
I second that!!! ♥️
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Jerelle Joseph @jerelleaj.bsky.social · 03/07/2025
Huge congratulations to @alinaemelianova.bsky.social Pablo and Daniel on their paper on small-molecule partitioning into condensates now published in JACS Au and selected as ACS Editor’s Choice!!! pubs.acs.org/doi/full/10....
pubs.acs.org
Prediction of Small-Molecule Partitioning into Biomolecular Condensates from Simulation
Predicting small-molecule partitioning into biomolecular condensates is the key to developing drugs that selectively target aberrant condensates. However, the molecular mechanisms underlying small-mol...
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Reposted by Jerelle Joseph
Jeremy Schmit @schmitbiophysics.bsky.social · 28/06/2025
Can't say enough about the Condensates program at @kitp-ucsb.bsky.social. Invigorating discussions, fantastic facilities, and a beautiful location (a place I consider "home"). Thanks to @weber-lab.bsky.social, @jerelleaj.bsky.social, @zwickergroup.bsky.social, and Frank Julicher for organizing!
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Jerelle Joseph @jerelleaj.bsky.social · 23/06/2025
Few more days left to nominate a rising star in bioengineering! Self-nominations are welcomed!
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Jerelle Joseph @jerelleaj.bsky.social · 16/06/2025
“Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” The conference associated with our #KITP program on condensates runs for the next three days. Looking forward to meeting everyone and the discussions! www.kitp.ucsb.edu/activities/b...
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Jerelle Joseph @jerelleaj.bsky.social · 15/06/2025
There’s nothing quite like #KITP! So grateful that we got the opportunity to put this on! The fun continues…🥰
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Jerelle Joseph @jerelleaj.bsky.social · 29/05/2025
This was a big week for the group! Our four seniors graduated and made us very proud. Ethan graduates as a Sachs Scholar, Ian secured several minors, Daniel won the MacCracken Senior Thesis Award from SEAS, and Caroline earned the highest awards in both CBE and Engineering!
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dimitristypas.bsky.social @dimitristypas.bsky.social · 27/05/2025
@natsmb.nature.com has launched new content this month, namely Q&As. This interview with Dr. Joseph @jerelleaj.bsky.social‬ www.nature.com/articles/s41... highlights what's great about these pieces. Get to learn about the scientist and their interesting work (consensates/computational biol)!
nature.com
Jerelle Joseph: seeing biomolecular condensates with computation - Nature Structural & Molecular Biology
Jerelle Joseph is an assistant professor at the Department of Chemical and Biological Engineering and the Omenn–Darling Bioengineering Institute at Princeton University in New Jersey. We contacted Jer...
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Jerelle Joseph @jerelleaj.bsky.social · 22/05/2025
See u all in Santa Barbara!!
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Jerelle Joseph @jerelleaj.bsky.social · 16/05/2025
Thanks to @natsmb.nature.com for interviewing on our work: “seeing biomolecular condensates with computation” www.nature.com/articles/s41...
nature.com
Jerelle Joseph: seeing biomolecular condensates with computation - Nature Structural & Molecular Biology
Jerelle Joseph is an assistant professor at the Department of Chemical and Biological Engineering and the Omenn–Darling Bioengineering Institute at Princeton University in New Jersey. We contacted Jer...
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Jerelle Joseph @jerelleaj.bsky.social · 14/05/2025
Yesterday was a great day to be at WashU!
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Jerelle Joseph @jerelleaj.bsky.social · 05/05/2025
Join our interdisciplinary team developing computational approaches to understand and engineer biomolecular condensates. We’re looking for a postdoc—please apply or share with interested persons! 👩🏽‍💻💧🧬 puwebp.princeton.edu/AcadHire/app...
puwebp.princeton.edu
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Jerelle Joseph @jerelleaj.bsky.social · 29/04/2025
Congratulations to our 4 seniors (Dan, Ethan, Caroline and Ian) on defending their theses today in the #CBE poster session!! We’re so proud! They’re heading off to Rockefeller, Caltech, Fancy Industry job, and UCLA in the fall! 3/4 were the first 3 juniors in the group. *Cue the tears*😭😭
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Jerelle Joseph @jerelleaj.bsky.social · 18/04/2025
📣 Calling all Rising Stars in Biological Engineering. Nominate someone or self nominate: forms.gle/EszC1AvRFpfN...
forms.gle
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Jerelle Joseph @jerelleaj.bsky.social · 10/04/2025
Had the best time at Duke over the last three days! Many many thanks to @gladfelterlab.bsky.social and the entire Center for Quantitative Living Systems for being such amazing hosts!
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Jerelle Joseph @jerelleaj.bsky.social · 27/03/2025
The “social” network inside condensates is quite cliquey 🙃🙃 co-lead by undergrad student Daniel Tan w/ postdoc Dilimulati 🥳🥳🥳 Preprint out!! www.biorxiv.org/content/10.1...
biorxiv.org
Interaction networks within biomolecular condensates feature topological cliques near the interface
Biomolecular condensates are typically maintained by networks of molecular interactions, with canonical examples including those formed by prion-like low complexity domains (LCDs) of proteins. Single-...
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Jerelle Joseph @jerelleaj.bsky.social · 24/03/2025
Going to Cali and back to the east coast twice in one week is an extreme sport! #aps #acs #itsawrap
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Jerelle Joseph @jerelleaj.bsky.social · 20/03/2025
What a week!
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Jerelle Joseph @jerelleaj.bsky.social · 12/03/2025
This summer in beautiful Santa Barbara we will run a 3-day conference on “Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” June 16 to 18th. Register now: www.kitp.ucsb.edu/activities/b...
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Reposted by Jerelle Joseph
Alina Emelianova @alinaemelianova.bsky.social · 07/03/2025
Predicting small molecule partitioning into biomolecular condensates is key for designing drugs that target aberrant condensates. But what drives partitioning at the molecular level? (1/6) 🧵👇
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