Sign in

Eloïse Bertiaux

@ebertiaux.bsky.social
104 followers 112 following 6 posts
PostsRepliesMedia
Reposted by Eloïse Bertiaux
Melanie Bonhivers @mbonhivers.bsky.social · 29/07/2026
Congratulations to Karine Frénal (@frenal-toxolab.bsky.social) for her ANR PRC ON_TRACK and to Eloïse Bertiaux (@ebertiaux.bsky.social) for her ANR JCJC Quart-ER. The ProParaCyto lab is very happy to see these projects being developed !
031
Reposted by Eloïse Bertiaux
EuroCilia2027 @eurocilia.bsky.social · 24/07/2026
📣 Abstract submission and early registration are now OPEN for the 7th European Cilia Conference—an official EMBO workshop! 📅 8–12 March 2027 📍 Stresa, Italy Submit and register: meetings.embo.org/event/27-cilia www.eurocilia.eu #EMBOCilia #Cilia2027
01513
Reposted by Eloïse Bertiaux
abberior @abberior.rocks · 24/07/2026
Tubulin (green) & #BILBO1 (magenta) in #Trypanosoma brucei. 3D MINFLUX shows BILBO1's nanoscale architecture at the flagellar pocket collar. More: Zelená et al., PLOS Biology (link in reply). Image: Mélanie Bonhivers (@mbonhivers.bsky.social), CNRS/Univ. Bordeaux #fluorescencefriday #MINFLUX
0105
Reposted by Eloïse Bertiaux
Melanie Bonhivers @mbonhivers.bsky.social · 12/06/2026
The CNRS has opened a Junior Professor Chair (CPJ) call in Parasitology, and the Microbiologie Fondamentale et Pathogénicité (MFP, Bordeaux) laboratory is among the potential host institutions. More information: www.insb.cnrs.fr/fr/cnrsinfo/... #Parasitology #Protozoology #ResearchJobs #CNRS
insb.cnrs.fr
Junior Professor Chairs (CPJ) 2026 – CNRS Biology
CNRS Biology is recruiting researchers through its Junior Professor Chair (CPJ) program, subject to final approval by the French Ministry of Higher Ed
1813
Reposted by Eloïse Bertiaux
Ali Shaib @alishaib.bsky.social · 01/06/2026
Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...
1018373
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 18/05/2026
Combined KIN2A and KIN2B knockdown showed that they were involved in IFT and flagellar length control, @ebertiaux.bsky.social picked up by developing the grow-and-lock model doi.org/10.1016/j.cu... Related findings were made by the group of @mattwelchlab.bsky.social doi:10.1242/jcs.129213
121
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 18/05/2026
Flagella can be assembled by IFT without the canonical heterotrimeric kinesin! Grab a cup of tea or coffee and follow a story that started 25 years ago
1137
Reposted by Eloïse Bertiaux
bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 13/05/2026
Life without heterotrimeric kinesins: trypanosomatids use a combination of homodimeric kinesin-2 motors to drive intraflagellar transport www.biorxiv.org/content/10.64898/20…
036
Reposted by Eloïse Bertiaux
Royal Microscopical Society @royalmicrosoc.bsky.social · 12/05/2026
We are very pleased to announce Prof. Paul Guichard and Dr. Virginie Hamel @centriolelab.bsky.social as joint winners of the RMS Award for Light Microscopy 🔬 👏 🏅 Huge congratulations to both! Read more about Paul and Virginie's achievements: www.rms.org.uk/resource/pro...
Prof. Paul Guichard (left) and Dr. Virginie Hamel both pictured smiling against a plain background. Head and shoulders images.
57421
Reposted by Eloïse Bertiaux
club CFC @club-cfc.bsky.social · 19/03/2026
Hello everyone, we had a great meeting yesterday @institutimagine.bsky.social , thanks again to all the speakers for their very interesting talks on primary and motile #cilia #flagella #ciliopathies! Next one is organized by Caroline Brun, Marine Laporte, Véronique Morel in Aussois in September!
1107
Reposted by Eloïse Bertiaux
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 25/12/2025
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
012532
Reposted by Eloïse Bertiaux
Marine Laporte @marinelap.bsky.social · 25/12/2025
As a Christmas present, our Jove paper with @ebertiaux.bsky.social is out and available for everyone ! Check this out & thanks @centriolelab.bsky.social for the nice highlight
0269
Reposted by Eloïse Bertiaux
PLOS Biology @plosbiology.org · 10/12/2025
How does C2CD3 contribute to distal appendage formation in centrioles? @ebertiaux.bsky.social @centriolelab.bsky.social show that C2CD3 architecturally organizes the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
C2CD3 localizes to a ring structure observed in the lumen of the distal centriole by in situ cryo-electron tomography. Top: Confocal image of an expanded mouse photoreceptor cell immunolabeled for tubulin (magenta) and C2CD3 (green). DC, daughter centriole; BB, basal body; TZ, transition zone; CC, connecting cilium. Scale bar: 500 nm. Middle: In situ cryo-tomogram slices taken along the longitudinal axis of the centriole and connecting cilium. White arrowheads indicate microtubule triplets, black arrowheads indicate microtubule doublets, orange arrowheads mark the luminal ring structure, and yellow highlights the membrane. Scale bar: 50 nm. Bottom:  Model of the architecture of the distal region of the human centriole.
094
Reposted by Eloïse Bertiaux
Ben Engel @cellarchlab.com · 10/12/2025
Happy to share our fun team-up with @centriolelab.bsky.social & @stearnslab.bsky.social to reveal the architecture of the mammalian centriole’s Distal Ring 🛟. Very cool multiscale integration of #UExM 📏🔬with #CryoET ❄️🔬. Congrats to @ebertiaux.bsky.social & @computingcaitie.bsky.social #TeamTomo 🧪
05318
Reposted by Eloïse Bertiaux
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 10/12/2025
🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.
07120
Eloïse Bertiaux @ebertiaux.bsky.social · 10/12/2025
Thrilled to share that my postdoc paper has just been a published in @plosbiology.org ! Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work. Proud of what we achieved together! journals.plos.org/plosbiology/...
journals.plos.org
The luminal ring protein C2CD3 acts as a radial in-to-out organizer of the distal centriole and appendages
The centriolar protein C2CD3 has been suggested to be crucial for distal appendage formation in centrioles, but its precise mechanistic role remains unclear. Using a combination of ultrastructure expa...
1276
Reposted by Eloïse Bertiaux
Rémi Fronzes @fronzeslab.bsky.social · 21/11/2025
Our latest T7SS study is now out in Science Advances! We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery. www.science.org/doi/10.1126/...
science.org
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
48841
Eloïse Bertiaux @ebertiaux.bsky.social · 18/11/2025
Honored to receive the FEBS Booster Funds 2025. My sincere thanks to FEBS for this recognition and their support of early-career researchers. This funding will greatly help advance my work. Congratulations as well to all fellow 2025 awardees.
3142
Reposted by Eloïse Bertiaux
Manuel Thery @manuelthery.bsky.social · 14/10/2025
We hire! The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities. More details here: cytomorpholab.com/index.php/jo...
08373
Reposted by Eloïse Bertiaux
PLOS Biology @plosbiology.org · 13/10/2025
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
A Trypanosoma brucei cell visualized by confocal microscopy after ultrastructure expansion. The cell was immunolabelled for the BILBO1 protein (yellow) and stained with fluorescent NHS-ester (grey). The flagellar pocket is highlighted in pink. Credit: Marie Zelená
0103
Reposted by Eloïse Bertiaux
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 28/08/2025
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1... Soon at @spirochrome.com Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
211447
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 29/07/2025
Be ready for an exciting meeting!
061
Reposted by Eloïse Bertiaux
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 21/07/2025
🚨 New EMBO Practical Course! Ultrastructure Expansion Microscopy: From Cells to Tissue 🔬 📅 20–24 Apr 2026 | 📍 EMBL Heidelberg Co-organised with @banterlegroup.bsky.social @gautamdey.bsky.social 💡 Register your interest to get notified when registration opens: 🔗 www.embl.org/about/info/c...
16129
Reposted by Eloïse Bertiaux
LabEx ParaFrap @parafrap.bsky.social · 10/06/2025
💼 PostDoc position (2 years) on Trypanosoma brucei | Bordeaux, France | Lab MFP with Dr. Frédéric Bringaud @univbordeaux.bsky.social @cnrsaquitaine.bsky.social 🔬 Glycerol and differentiation in Trypanosoma brucei 🗓️ Deadline: September 15. Start: by November 2025 labex-parafrap.fr/fr/emplois/4...
043
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 07/07/2025
On Friday, Daniel left us after more than 4 happy years in the lab @pasteur.fr and a great paper published today in @jcellsci.bsky.social as well as other contributions! Many thanks for everything! journals.biologists.com/jcs/article-...
1143
Reposted by Eloïse Bertiaux
abberior @abberior.rocks · 27/06/2025
#Trypanosoma, fixed, expanded, and imaged with #STED, stained for tubulin. Scale bar refers to expanded specimen, original structures are 3-3x smaller. Image courtesy: @mbonhivers.bsky.social, MFP, CNRS, Univ. Bordeaux, France #fluorescencefriday #ExM #STEDmicroscopy
0176
Reposted by Eloïse Bertiaux
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 19/06/2025
🚨 New preprint! Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM www.biorxiv.org/content/10.1...
011945
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 27/05/2025
Honoured to have been introduced today by former lab member @ebertiaux.bsky.social at the annual Microbiology day of New Aquitaine. My first talk in a (former) church!
191
Reposted by Eloïse Bertiaux
PLOS Biology @plosbiology.org · 19/05/2025
#Phosphofructokinase (PFK) is considered an irreversible glycolytic #enzyme. This study shows that #Trypanosomes are the only known organism to use PFK in the gluconeogenic direction under normal conditions, likely due to its compartmentalization within glycosomes @plosbiology.org 🧪 plos.io/43r84Qc
Left: Schematic representation of the glycerol metabolism of PCF trypanosomes. This figure shows glycerol metabolism leading to the excreted end products, succinate and acetate in the glycosomes and the mitochondrion, respectively, while gluconeogenesis (production for G6P from G3P and DHAP) is represented in red. The oxidative and non-oxidative branches of the pentose-phosphate pathway (PPP) are highlighted in blue and purple, respectively. The three enzymes addressed in this study (PFK, FBPase, and SBPase), possibly responsible for production of F6P from F1,6BP, are boxed. Right: Images show the glycosomal (top) and cytosolic (bottom) localization of MaLionR-Myc-GPDH and MaLionG by immunofluorescence assays on the OEMaLionR-Myc-GPDH.i and OEMaLionG cell lines, respectively, by using an anti-aldolase immune serum as a glycosomal marker.
061
Reposted by Eloïse Bertiaux
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 19/03/2025
Huge congratulations to @marinelap.bsky.social for receiving the 2025 Young Researcher Award! 🏆👏 sbcf.fr/en/newslette...
2294
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 13/03/2025
Brilliant work with unprecedented level of resolution of the trypanosome axoneme!
061
Reposted by Eloïse Bertiaux
ProParaCyto @derrickrrobinson.bsky.social · 07/03/2025
Assistant prof / MCF post available in ProParaCyto.
034
Reposted by Eloïse Bertiaux
BIC_Bordeaux @bic-bordeaux.bsky.social · 03/03/2025
March #ImageOfTheMonth goes to M.Bonhivers from MFP lab (UMR 5234). Trypanosoma brucei cell was extracted in detergent, expanded 4.2 fold using U-ExM, labelled for the microtubule cytoskeleton (magenta) and for the Hook Complex (yellow), and images usinf scanning confocal microscopy.
0195
Reposted by Eloïse Bertiaux
Ben Liffner @benliffner.bsky.social · 04/03/2025
A massive thanks to @bladerlab.bsky.social for the opportunity to put this mSphere of influence article together! Also @dvorinlab.bsky.social, @ebertiaux.bsky.social, Brochet Lab, & @centriolelab.bsky.social for doing science that shows off why parasites are cool! journals.asm.org/doi/10.1128/...
journals.asm.org
mSphere of Influence: The ever-expanding universe of parasite cell biology | mSphere
Single-celled apicomplexan parasites have to grow, replicate, and divide all of the organelles of a eukaryotic cell all while being a tiny fraction of the size of most other eukaryotes. For example, a...
1123
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 04/03/2025
Thanks to a new mass spec pipeline for analysis of the #tubulin tail, the team of Julia Chamot-Rooke and Mariette Matondo revealed a few surprises for #trypanosome beta-tubulin: -a new glutamylation site -far less exhaustive detyrosination Preprint here: www.biorxiv.org/content/10.1...
0114
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 17/02/2025
A video clip to see #trypanosomes in #3D #FIB-SEM Many thanks to Valérie Zeitoun and Jeanne Fenouil for their patience during the recording and to Adeline Mallet and Manu Majrouh at the UBI of @pasteur.fr www.pasteur.fr/fr/journal-r...
pasteur.fr
Le coupable de la Maladie du Sommeil
Plongée inédite au cœur du trypanosome, le parasite responsable de la maladie du sommeil !Transmise par la piqûre de la mouche tsé-tsé, cette maladie touche plus de 30 pays d’Afrique subsaharienne. Ap...
093
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 11/02/2025
We propose a model where the new flagellum grows in a linear manner while the old one is locked but shrinks slightly, hence requiring unlocking and compensation after cell division, leading to such multicoloured flagella following induction/deinduction/reinduction of tagged tubulin 😉
0125
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 11/02/2025
Solving 25 years of frustration, Daniel Abbühl managed to tag trypanosome tubulin and to express it in an inducible manner, hence revealing flagellum assembly! A tour-de-force! Preprint here: www.biorxiv.org/content/10.1...
24514
Reposted by Eloïse Bertiaux
LabEx ParaFrap @parafrap.bsky.social · 10/02/2025
Parasite of the month in Trends in Parasitology: #Trypanosoma equiperdum. By Perrine Hervé, Frédéric Bringaud and Loïc Rivière (ParaFrap Team) @cp-trendsparasitol.bsky.social
021
Reposted by Eloïse Bertiaux
Armando Rubio Ramos @bioarm.bsky.social · 24/01/2025
Very interesting work here: centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends rupress.org/jcb/article/...
rupress.org
Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends | Journal of Cell Biology | Rockefeller University Press
Iyer et al. combine in vitro reconstitution assays with cryo-electron tomography, biophysical, and cell biological approaches to show that two centriolar p
011
Reposted by Eloïse Bertiaux
Joel Vega-Rodriguez @jvr-lab.bsky.social · 19/01/2025
Our paper on U-ExM for mosquito tissues (MoTissU-ExM) in BMC methods! Great collaboration with @sabsalon.bsky.social and @benliffner.bsky.social bmcmethods.biomedcentral.com/articles/10....
bmcmethods.biomedcentral.com
Mosquito Tissue Ultrastructure-Expansion Microscopy (MoTissU-ExM) enables ultrastructural and anatomical analysis of malaria parasites and their mosquito - BMC Methods
Background Study of malaria parasite cell biology is challenged by their small size, which can make visualisation of individual organelles difficult or impossible using conventional light microscopy. ...
0147
Reposted by Eloïse Bertiaux
Rémi Fronzes @fronzeslab.bsky.social · 16/01/2025
Bravo @pasteur.fr !!! Fier d’avoir été Pasteurien !!! (Le directeur de l’époque Christian Bréchot m’avait dit qu’on le reste toute sa vie)
091
Reposted by Eloïse Bertiaux
Philippe Bastin's Lab @bastinlab.bsky.social · 16/01/2025
Come and celebrate the exceptional career of Mark Carrington (24th March at University of Cambridge)!
0148
Reposted by Eloïse Bertiaux
Mill_lab @cilialab.bsky.social · 14/01/2025
Our 50th @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium kicked off with #UExM masterclass! Mysteries & hierarchies of #tubulin #PTMs in #ConnectingCilium #Bulge #IRDs- Olivier Mercey @centriolelab.bsky.social www.embopress.org/doi/full/10.... #ukcilia2025 /1
Acknowledgement slide of Olivier Mercey's lab, collaborators and funders showing ultra expansion microscopy images of mouse photoreceptor connecting cilia.
1174