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Joel Selkrig

@jselkrig.bsky.social
584 followers 459 following 30 posts

Updates from the Selkrig Lab. Exploring the function of secreted bacterial proteins in the context of infection and the gut microbiome. www.ukaachen.de/kliniken-institute/institut-fuer-medizinische-mikrobiologie/forschung/ag-selkrig/

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Reposted by Joel Selkrig
Nature Structural & Molecular Biology @natsmb.nature.com · 30/09/2026
New online: A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity
dlvr.it
A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity
Nature Structural & Molecular Biology, Published online: 30 September 2026; doi:10.1038/s41594-026-01877-6Koenig et al. present a phosphoproteome atlas of 33 human cell lines covering >200,000 phosphosites, advancing cellular kinase activity scoring and drug sensitivity prediction, providing a resource for cell signaling insights and precision oncology.
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Joel Selkrig @jselkrig.bsky.social · 29/09/2026
How do gut bacteria cope with both proteolytic stress and phage attack? 🧵👇 Our latest preprint is live! Ulcerative colitis (UC) creates a distinct gut environment: protease activity rises, the virome shifts, and phages expand. #Microbiome #Bacteriophages #IBD www.biorxiv.org/content/10.6...
biorxiv.org
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Joel Selkrig @jselkrig.bsky.social · 29/09/2026
How do gut bacteria cope with both proteolytic stress and phage attack? 🧵👇 Our latest preprint is live! Ulcerative colitis (UC) creates a distinct gut environment: protease activity rises, the virome shifts, and phages expand. #Microbiome #Bacteriophages #IBD www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Joel Selkrig
Lars Juhl Jensen @larsjuhljensen.bsky.social · 15/09/2026
A video on the STRING version 12.5 update: cleaner functional association network thanks to improved text mining and a new directed regulatory network! youtu.be/tTf_aIE8Wxw #bioinformatics #networkbiology #systemsbiology #textmining
youtu.be
STRING version 12.5: A brief introduction to the quantitative and qualitative changes
YouTube video by Lars Juhl Jensen
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Reposted by Joel Selkrig
Max-Planck-Gesellschaft @maxplanck.de · 09/09/2026
We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack
Call for independent Max Planck Research Groups
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Reposted by Joel Selkrig
Julian Parkhill @julianparkhill.bsky.social · 08/09/2026
Chair in Bacteriology in Cambridge Department of Medicine. A great opportunity. Please circulate. www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Professor in the field of Bacteriology
Strengthening Cambridge's leadership in bacteriology research Bacterial infection and antimicrobial resistance remain among the most pressing global health challenges of our time. At Cambridge, the De...
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Reposted by Joel Selkrig
Janelia FlyEM @janelia-flyem.bsky.social · 04/09/2026
We're thrilled with the publication of the Male CNS Connectome! www.cell.com/cell/fulltex... Also check out this (growing) collection of companion papers: www.cell.com/consortium/m...
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Tatta Bio @tattabio.bsky.social · 04/09/2026
UniProt is where most researchers start when they want to understand a protein. As of today, prokaryotic entries there will show something new: genomic context, powered by SeqHub, right in the Sequence section of the page.
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Reposted by Joel Selkrig
Joe Zackular @joeyzacks.bsky.social · 03/09/2026
Excited to share new work from my lab showing that early-life colonization with C. difficile remodels the developing infant gut, published today in @science.org! This study was co-led by two truly amazing scientists: @haidermanzer.bsky.social and Alexa Semon. www.science.org/doi/10.1126/...
science.org
Early-life colonization with Clostridioides difficile remodels the developing gut
Clostridioides difficile causes severe disease in adults but commonly colonizes infants asymptomatically. The consequences of early-life colonization on host development remain unknown. In a neonatal ...
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Hiten Madhani @hitenmadhani.bsky.social · 27/08/2026
Most basic science departments at UCSF are having faculty searches this year. Biochemistry & Biophysics, Microbiology & Immunology, Cellular and Molecular Pharmacology, Physiology and more. We're looking for new and exciting science and nice people. You'll find them all at aprecruit.ucsf.edu
aprecruit.ucsf.edu
Welcome - AP Recruit
University of California, San Francisco Online Faculty Recruitment
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Thomas Clavel @tclavel.bsky.social · 26/08/2026
Drawing on the team’s knowledge acquired over the years, we share our thoughts here on how to enhance microbiome research with FAIR collections of microbial strains: 🔥 www.nature.com/articles/s41... @nfdi4microbiota.bsky.social, @spp2474.bsky.social, @dsmz.bsky.social, @natmicrobiol.nature.com.
nature.com
A roadmap to create FAIR collections of microbial strains - Nature Microbiology
Here the authors propose guidance on the process of establishing a state-of-the-art collection of microorganisms, including project planning, strain deposition and the naming of new taxa.
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Nonia Pariente @npariente.bsky.social · 26/08/2026
*Is the scientific paper still a fraud?* How we write scientific papers does not reflect how we do science, argues @prof-tregoning.bsky.social This matters in the AI age because it masks the human in the process @plosbiology.org plos.io/4xn4OlZ
plos.io
Is the scientific paper still a fraud?
How we write scientific papers does not reflect how we do science, masking the human in the process by design. This Perspective invites us to consider the structure of the scientific paper, and the ne...
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Reposted by Joel Selkrig
Typas Lab @typaslab.bsky.social · 20/08/2026
Excited to share our paper with @savitski-lab.bsky.social, led by @tarabartolec.bsky.social, Karin Mitosch & Clément Potel, out now in @nature.com. We show that T7 phage broadly disables bacterial defenses using a unique ‘loose cannon’ protein kinase. www.nature.com/articles/s41...
nature.com
Pervasive phosphorylation by phage T7 kinase disarms bacterial defences - Nature
The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.
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Reposted by Joel Selkrig
Marianne Grognot @grognotlab.bsky.social · 20/08/2026
[Fresh Preprint] Some pathogens swim to infect, but what about the gut microbiota? Spoiler alert: they swim, particularly in inflamed states 🔥 And they refuse to swim like typical gut bacteria models (sorry, E. coli's run-tumble!). Proud of Maria's work, within SFB1382. doi.org/10.64898/202...
doi.org
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BejaLabTechnion @bejalab.bsky.social · 19/08/2026
Pervasive phosphorylation by phage T7 kinase disarms bacterial defences www.nature.com/articles/s41...
nature.com
Pervasive phosphorylation by phage T7 kinase disarms bacterial defences - Nature
The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.
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Mateus lab @mateuslab.com · 08/08/2026
Bolor's paper is now out! Read the final story here: www.nature.com/articles/s41... See below 👇 for the main highlights
nature.com
Systematic profiling of growth interactions in human gut microbiome species - Nature Communications
Here, Buyanbadrakh et al. systematically map growth interactions among gut bacteria, revealing predominantly inhibitory effects, and identifying extracellular vesicles and pH modulation as mechanisms ...
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Noah Whiteman @nkwhiteman.bsky.social · 06/08/2026
I’m thrilled to share that our search for a tenure-track colleague in my *truly wonderful and collegial* Genetics, Genomics, Evolution and Development Division in the MCB Department at Berkeley @berkeleymcb.bsky.social is live! Please share this broad search widely: aprecruit.berkeley.edu/JPF05481
aprecruit.berkeley.edu
Assistant Professor -Genetics, Genomics, Evolution, and Development - Molecular and Cell Biology
University of California, Berkeley is hiring. Apply now!
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Nichole Broderick, PhD @nabroderick.bsky.social · 06/08/2026
Final call for abstracts! 8th Conference on Model Hosts, Oct 3-8th Sissi Crete. Thanks to support from @microbiologysociety.org and @femsmicro.org we have funding for a number of trainee travel awards - submit your abstract and apply today! aegeanconferences.org/conferences/...
Image of an Aegean coastal town advertising a scientific conference on model hosts.
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Cascales Lab @cascaleslab.bsky.social · 07/08/2026
Happy to share our latest review on the "Structure and function of the #T9SS for protein secretion and cellular motility" to be published in the incoming volume 80 of Annual Review in Microbiology. Kudos to Yaelle Aouizerate and @thicoz.bsky.social ! www.annualreviews.org/content/jour...
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EMBL @embl.org · 03/08/2026
Behind every great scientist is a great community! @lisamaierlab.bsky.social, EMBL's 2026 John Kendrew Award recipient, reflects on how mentorship and support at EMBL shaped her journey into pioneering microbiome research. Read more about her journey 👉 www.embl.org/news/people-...
embl.org
A journey through the microbiome, shaped by growth and support | EMBL
EMBL alumna Lisa Maier, recipient of the 2026 John Kendrew Award, discusses her scientific achievements, the importance of science engagement, and how she carries on the ‘EMBL spirit’
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André Nadler @nadlerlab.bsky.social · 29/07/2026
Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...
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EMBL Events @events.embl.org · 23/07/2026
Exciting opportunity: EMBL CPP Fellowships are open for applications until 31 July! Stay for 1 – 6 months at any of EMBL's six sites 🧪 Who's eligible: • Currently employed PhD researchers or postdocs • All nationalities, no age limit • First-time visitors to EMBL s.embl.org/cpp-fellowship
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SourjikLab @sourjik-lab.bsky.social · 21/07/2026
Together with @thanbichlerlab.bsky.social, we are looking for an ambitious PhD student to develop fluorescence imaging for anaerobic bacteria. Check out this and other positions that are announced as a part of the M4C Excellence cluster here: stellenangebote.uni-marburg.de/jobposting/2...
stellenangebote.uni-marburg.de
Doctoral and Postdoctoral Researcher Positions in the Cluster of Excellence ‘Microbes for Climate’
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Rachel M. Wheatley @rachelmwheatley.bsky.social · 20/07/2026
New updates to AllTheBacteria - some super cool results and an amazing resource for the community
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Ahmed Moustafa @ahmedmicrobes.bsky.social · 20/07/2026
Check our preprint and this global effort "AllTheBacteria" to uniformly process all public bacterial and archaeal genomes and make them accessible, searchable and AI-ready.
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Anthony Shiver @anthonyshiver.bsky.social · 17/07/2026
The labs of KC Huang and Justin Sonnenburg at Stanford are working on an exciting and impactful project related to infant probiotics and are hiring a Life Science Research Professional to be part of that team. Take a look at the posting if you're interested. Please share/apply
careersearch.stanford.edu
Life Science Research Professional 2
Applying a comprehensive understanding for the theories and methods of a life science discipline, perform work directly involved in research projects, interpreting results and participation in experim...
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Géraldine Laloux @lalouxlab.bsky.social · 09/07/2026
New preprint! We show that the bacterial predator B. bacteriovorus deploys a unipolar Tad nanomachine for irreversible attachment to prey and invasion. @coralietesseur.bsky.social used CRISPRi+microfluidics to overcome barriers associated with essential systems in an obligate predatory lifestyle 🦠
biorxiv.org
A polarity-controlled Tad nanomachine enables prey invasion in a bacterial predator
Type IV pili are dynamic surface appendages assembled by envelope-spanning nanomachines that mediate diverse bacterial interactions, yet how these systems are adapted to predatory lifestyles remains p...
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National Academy of Sciences @nasonline.org · 09/07/2026
Support #microbiology research by nominating a scientist for the 2027 Selman A. Waksman Award in Microbiology!🦠Preference will be given to early-career scientists and those whose work hasn’t been recognized by other large prizes. Learn more: www.nasonline.org/award/selman... #NASaward
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Kimberly Kline 🏔 @kimingeneva.bsky.social · 09/07/2026
🚨Join us at the University of Geneva! We're seeking an outstanding junior researcher to apply for an ERC or SNSF Starting Grant with our institutional support in host–pathogen interactions, bacteriology, virology, parasitology, or mycology. www.unige.ch/medecine/mim... Please share!
unige.ch
Open call : MIMOL Junior Group Leader’s application for a Starting Grant - Microbiology and molecular medicine - UNIGE
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Coralie Tesseur @coralietesseur.bsky.social · 09/07/2026
So excited to share our new preprint! 🎉🤩 Check it out to discover how we investigated the role and spatiotemporal dynamics of an essential Tad nanomachine during the lifecycle of our favorite bacterial predator, B.bacteriovorus 🦠 Many thanks to everyone who made this work possible!
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CIDRAP @cidrap.bsky.social · 07/07/2026
Shigella vaccine shows promise in phase 2 trial. 💉 The live-attenuated vaccine showed high levels of protection against one of the leading causes of diarrhea worldwide. Read more: bit.ly/3SDC7T7 📷: Stephanie Rossow / CDC
Artistic rendering of Shigella bacteria under the microscope
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Ylva Ivarsson @ivarssonlab.bsky.social · 06/07/2026
Excited to share our preprint introducing ASHI: the Atlas of SLiM-mediated Human protein-protein Interactions. By screening 800+ domains against the human intrinsically disordered regions, we map 20,000 SLiM-mediated interactions. Many thanks to everyone involved! www.biorxiv.org/content/10.6...
biorxiv.org
An Atlas of Short Linear Motif-Mediated Human Protein-Protein Interactions
Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology. However, the global interaction landscape of human SLiMs remains...
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Reposted by Joel Selkrig
Wolfgang Huber @wkhuber.bsky.social · 01/07/2026
EMBL's new AI unit is recruiting. We are seeking a machine learning scientist to establish their independent research group bridging innovations in machine learning/AI with modern biology. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
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Pedro Beltrao @pedrobeltrao.bsky.social · 06/07/2026
My department @eth-dbiol.bsky.social at ETH Zurich is hiring for a tenured professor in mol cell bio and biochemistry (associate/full). The position is within the Institute of Biochemistry (www.bc.biol.ethz.ch) and it is fairly open within their scope of research. www.nature.com/naturecareer...
nature.com
Professor of Molecular Cell Biology and Biochemistry - Zurich, Switzerland job with ETH Zurich | 12861386
The Department of Biology at ETH Zurich invites applications for the above-mentioned tenured professorship at the Institute of Biochemistry
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Laura K. Jennings @laurakjennings.bsky.social · 29/06/2026
📢 We're hiring! The Department of Microbiology & Cell Biology at Montana State University is hiring an Assistant Professor of Microbiology. We welcome applicants working in microbial pathogenesis, immunology, genetics, microbial evolution, and related areas. Apply: jobs.montana.edu/postings/52009
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Typas Lab @typaslab.bsky.social · 29/06/2026
How can we harness the vast functional diversity of microbes on our planet? Join us at EMBL Heidelberg from 8–10 December 2026 to hear about ongoing efforts to decode gene function and organisation in human gut microbes, and to present your own research. www.embl.org/about/info/c...
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Cell Host & Microbe @cp-cellhostmicrobe.bsky.social · 25/06/2026
Universal microbiome signature for CRC Large gut microbiome meta-analysis of colorectal cancer uncovers CRC microbiome signatures universal across ages & sequencing methods & modifiable by dietary interventions, ie fiber. www.cell.com/cell-host-mi...
cell.com
Meta-analysis reveals microbiome signatures for colorectal cancer that are universal across age groups and sequencing methods
Pekel, Karcher, et al. present the largest gut microbiome meta-analysis of colorectal cancer to date, integrating 6,779 amplicon and shotgun sequencing profiles. They establish a robust microbiome sig...
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One Health Microbiome Center @psumbiome.bsky.social · 22/06/2026
World Microbiome Day is almost here! As we count down to June 27, we're highlighting trainees advancing microbiome science. Today's feature: Jessica Gaydos, a PhD candidate in Guy Townsend's lab at Penn State College of Medicine. @worldmicrobiomeday.bsky.social | #WorldMicrobiomeDay #OneHealth
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Louis Ates @mycolates.bsky.social · 12/06/2026
I'm incredibly proud to share our paper on the preclinical evaluation of the BNT164 mRNA tuberculosis vaccine candidates. Now online in the final version at Nature Immunology. www.nature.com/articles/s41...
nature.com
mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models - Nature Immunology
Here the authors characterize mRNA-based tuberculosis vaccine candidates BNT164a1 and BNT164b1 and show that they are immunogenic, well tolerated and efficacious in preclinical animal models.
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Nichole Broderick, PhD @nabroderick.bsky.social · 10/06/2026
Pls share: Early Decision Deadline approaching (June 15th)- submit your abstracts! In addition to a great list of invited speakers, we anticipate selecting ~30 abstracts more for talks. Keen to highlight early career scientists. aegeanconferences.org/conferences/...
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Reposted by Joel Selkrig
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 06/06/2026
Flagellar system translocates T3SS effectors critical for Salmonella infection www.biorxiv.org/content/10.64898/20…
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Mike Inouye @mikeinouye.bsky.social · 20/04/2026
We are recruiting a PI in biomedical data science at @bakerresearchau.bsky.social in Melbourne! A fantastic opportunity and do get in touch if any q's! www.seek.com.au/job/91619982...
seek.com.au
Laboratory Head in Biomedical Data Science Job in Melbourne VIC - SEEK
Lead a biomedical data science lab, secure funding, publish research and collaborate globally to drive impactful cardiometabolic outcomes.
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Mateus lab @mateuslab.com · 20/04/2026
New preprint from the lab! We developed a new tool to identify prokaryotic species (down to the strain level) directly from mass spectrometry-based bottom up proteomics data. #teammassspec #microsky www.biorxiv.org/content/10.6...
biorxiv.org
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Leah Lavery @helloleahlavery.bsky.social · 23/03/2026
Congratulations to Dr. Julia Mahamid on receiving the 2026 Gottfried Wilhelm Leibniz Prize! 🎉 Her pioneering work in cryo-ET is reshaping our understanding of how molecular architecture drives cellular processes and disease. #teamtomo #LeibnizPrize #StructuralBiology #LifeSciences #Innovation
dfg.de
Julia Mahamid, Ph.D. – Gottfried Wilhelm Leibniz Prizewinner 2026
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Nichole Broderick, PhD @nabroderick.bsky.social · 20/03/2026
Excited to announce our new journal from @isme-microbes.bsky.social ISME Host Microbe is live and now accepting submissions. Look forward to receiving your papers! #Microsky 🧫 🦠
Image of the cover of the 1st volume of ISME Host Microbe a new official journal of the International Society for Microbial Ecology. Cover images shows a plant stomata with bacteria around and entering.
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Rob Klose @robklose.bsky.social · 13/03/2026
We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).
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Typas Lab @typaslab.bsky.social · 12/03/2026
Check the conference link: www.embl.org/about/info/c... Abstract submission & registration open, don’t miss out! #EMBLGutMicrobeFunction
embl.org
Unlocking the functional diversity of gut microbiomes
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Dr Monique Ryan @mon4kooyong.bsky.social · 12/03/2026
Join my campaign to properly fund medical research in Australia 🔬 www.moniqueryan.com.au/medical_rese...
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Artem Nemudryi @artemnemudryi.bsky.social · 09/03/2026
Our work on bacterial Schlafens in phage defense is out today @natmicrobiol.nature.com! Check out the final version here: rdcu.be/e7Bmz We are looking for postdocs and students to expand our team! Official postings are coming soon. Please reach out if you're interested! #phage #phagesky #microsky
rdcu.be
Bacterial Schlafen proteins mediate phage defence
Nature Microbiology - This study highlights that Schlafens are ancient, mechanistically conserved immune effectors that mediate antiviral immunity in organisms ranging from humans to bacteria.
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Tobias Warnecke @tobiaswarnecke.bsky.social · 05/03/2026
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you! 1/n
my.corehr.com
Job Details
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