Associate Professor in Biochemistry, Department of Chemistry for life sciences, Uppsala University

The following will be offered in this call:Up to 8 FPI positions associated with the “Proyectos de Generación de Conocimiento 2025” Call (funded by the Agencia Estatal de Investigación AEI- MICINN).Ch...

Eight integrated mutational footprints collectively explain the mutational processes in 85% of primary prostate cancer genomes.

Associate Professor in Biochemistry, Department of Chemistry for life sciences, Uppsala University

Abstract. During bacterial ribosome recycling, 70S ribosomes are split into subunits by ribosome recycling factor (RRF) and elongation factor G (EF-G). The

Abstract. Ribosomal RNA (rRNA) modifications cluster around the peptidyl transferase centre (PTC), the catalytic centre of the ribosome, yet their collecti

Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology. However, the global interaction landscape of human SLiMs remains...

Proteome-wide prediction and structural modeling of disordered protein interaction interfaces advance characterization of disease-associated variants in disordered protein regions.

The Department of Biology at ETH Zurich invites applications for the above-mentioned tenured professorship at the Institute of Biochemistry

Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology. However, the global interaction landscape of human SLiMs remains...

Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics

The nuclear pore complex (NPC) facilitates macromolecular exchange between the cytoplasm and nucleus; the selective nature of which is vital to proper cell functioning. Many DNA and some RNA viruses m...

Resistance to BRAF/MAPK inhibitors is a significant challenge in melanoma treatment, driven by adaptive and acquired mechanisms allowing tumor cells to evade therapy. We explored early signaling respo...

Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...

The ubiquitin-specific proteases (USPs) family is the largest family of human deubiquitinating enzymes (DUBs). While most USPs are agnostic to polyubiquitin linkage-type, their substrate specificity i...

Our new online seminar series explores the latest in protein modules research, featuring two talks on the second Monday of every month. Register to attend: tinyurl.com/PMCseminar2 Contact us for mo...

EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

Our new online seminar series explores the latest in protein modules research, featuring two talks on the second Monday of every month. Register to attend: tinyurl.com/PMCseminar2 Contact us for mo...

Base editors are made more precise through deaminase and gRNA engineering.

The ERC Synergy Grants 2026 call closed for applications on 5 November 2025. These are the preliminary data on the submitted proposals:

The Cell Signaling and Cell Cycle group, headed by Prof. Jakob Nilsson, is looking for a highly motivated and enthusiastic PhD student to establish novel CRISPR