Reposted by Jakob Schnabl-Baumgartner
DNA → RNA → protein.
From single mRNAs to an entire developing vertebrate embryo, we can now watch this last step unfold in real time.
Our paper is out today! 🐟🔬
www.science.org/doi/10.1126/...
science.org
Real-time single-molecule imaging in zebrafish embryos uncovers noncanonical translation
Precise spatiotemporal control of protein synthesis is essential during embryogenesis, yet directly measuring translation kinetics in vivo remains challenging in vertebrates. In particular, it remains...