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Gogl lab

@teamgogl.bsky.social
87 followers 121 following 54 posts

Quantitative interactomics team located at iBV (Nice, France). We study motif-mediated interactions using innovative systems biochemical approaches. Developers of the ProfAff affinity interactomics database.

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Bogi @zbobo2.bsky.social · 15/09/2026
We are looking for M1 and M2 interns! #teamGogl #Gogllab #ibv #biology #internship #job #interactomics #biochemistry #CNRS #Inserm #science
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Ylva Ivarsson @ivarssonlab.bsky.social · 11/09/2026
Do you want to be my colleague? We are recruiting a tenured #Associate #Professor in #Biochemistry to the Department of Chemistry for Life Sciences at #Uppsala University. Deadline for application November 20. www.uu.se/en/about-uu/...
uu.se
Associate Professor in Biochemistry - Uppsala University
Associate Professor in Biochemistry, Department of Chemistry for life sciences, Uppsala University
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Bogi @zbobo2.bsky.social · 28/07/2026
I am incredibly happy to share that my ANR JCJC project has been selected for funding! 🎉 I am deeply grateful to everyone who contributed to this proposal and supported me throughout the process. I can't wait to get started! #ANR #JCJC #Research #CNRS #Interactomics #TranscriptionFactors
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Gogl lab @teamgogl.bsky.social · 28/07/2026
Warm congratulations to Boglarka Zambo on her ACT-SYS project being selected for ANR funding! 🎉 #AAPG ACT-SYS will develop new systems biochemistry approaches for characterizing transcription factors. Looking forward to the exciting discoveries ahead!
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Ylva Ivarsson @ivarssonlab.bsky.social · 06/07/2026
Excited to share our preprint introducing ASHI: the Atlas of SLiM-mediated Human protein-protein Interactions. By screening 800+ domains against the human intrinsically disordered regions, we map 20,000 SLiM-mediated interactions. Many thanks to everyone involved! www.biorxiv.org/content/10.6...
biorxiv.org
An Atlas of Short Linear Motif-Mediated Human Protein-Protein Interactions
Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology. However, the global interaction landscape of human SLiMs remains...
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Marcin J. Suskiewicz @msuskiewicz.eurosky.social · 25/03/2026
Just finished reading this lovely paper by @zbobo2.bsky.social , @teamgogl.bsky.social , Gilles Travé, and collaborators, describing a new technique for quantifying transcription factor:DNA binding without protein purification. A short reader's summary follows.
febs.onlinelibrary.wiley.com
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Varjosalo_Lab @varjosal.bsky.social · 15/12/2025
🧬 New paper in Nature Communications! We found that POLE2,part of DNA polymerase ε,moonlights as a receptor for NPF motifs, binding 70+ proteins across replication, transcription & repair. The interactome is more interconnected than thought. @teamgogl.bsky.social 🇫🇮🇫🇷🇭🇺🇬🇧 www.nature.com/articles/s41...
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Gogl lab @teamgogl.bsky.social · 15/12/2025
Happy to share that our paper describing a new motif-mediated interactome is out in Nature Communications www.nature.com/articles/s41...
nature.com
The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein - Nature Communications
Short linear motifs in disordered protein regions are involved numerous protein–protein interactions. Here, the authors find that the POLE2 subunit of human DNA polymerase ε acts as a motif binding pr...
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CNRS Côte d'Azur @cnrscotedazur.bsky.social · 08/12/2025
👏 Félicitations à Gergő Gógl, chercheur @insermpacacorse.bsky.social à l'institut de Biologie Valrose, lauréat du programme Impulscience® de la Fondation Bettencourt Schueller. 👉 Découvrez les 7 scientifiques @cnrs.fr récompensés : www.cote-azur.cnrs.fr/fr/cnrsinfo/... @teamgogl.bsky.social
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Sophien Kamoun @kamounlab.bsky.social · 03/12/2025
I just published: ERC-Plus: jackpot science or missed chance to fix academia? My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building. medium.com/p/erc-plus-j...
medium.com
ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re…
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Cell - a Cell Press journal @cp-cell.bsky.social · 26/11/2025
Now online! Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells
dlvr.it
Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells
In vitro-derived insights into features that drive transcription factor binding to DNA, including motif-adjacent sequence, enable prediction of chromatin states and transcription factor occupancy in cells.
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Marcin J. Suskiewicz @msuskiewicz.eurosky.social · 24/11/2025
The second part of our (with @origichals.bsky.social and El Hadji) two-part review on non-covalent SUMO interactions is now published, focussing on SUMO-interacting motifs (SIMs), but discussing also other confirmed or potential SUMO-interacting elements.
portlandpress.com
Non-covalent SUMO interactions with ligases and effectors: SUMO-interacting motifs and beyond
SUMOylation, a protein post-translational modification (PTM) involving the covalent attachment of small ubiquitin-like modifier (SUMO), regulates a wide range of cellular processes. The key hallmark o...
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Gogl lab @teamgogl.bsky.social · 13/11/2025
According to ChatGPT, this is a three-stranded coiled coil.
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Gogl lab @teamgogl.bsky.social · 28/10/2025
profaff.fr The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.
profaff.fr
ProfAffv2 - Protein Affinity Database
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Gogl lab @teamgogl.bsky.social · 24/10/2025
Bluesky, we need your help! Why does plain eGFP partially colocalize with actin filaments in cells? (No bleed-through, observed in multiple cell lines. Whole plasmid sequenced.) #FluorescenceFriday #Microscopy
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Gogl lab @teamgogl.bsky.social · 17/10/2025
The Quantitative Interactomics and Disease-Related Networks team at iBV (Nice, France) is recruiting a Postdoctoral Researcher with expertise in recombinant protein technologies and biochemistry.
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Gogl lab @teamgogl.bsky.social · 15/10/2025
The old ProfAff server served us well, but it’s time for an upgrade! Can’t wait to launch the new version from our new institute!
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Gogl lab @teamgogl.bsky.social · 05/09/2025
I am incredibly grateful to the ERC reviewers for their time and support. This recognition is a true honor and means a great deal to me. Excited to keep pushing forward the characterization of so-far unexplored motif-mediated protein–protein interactions!
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Gogl lab @teamgogl.bsky.social · 08/08/2025
GPT-5 seems like a pretty significant step towards PhD level. But a PhD-level researcher knows the literature, i.e., names of researchers and contents of key papers, much better. Or maybe it's only because we are working in a very niche field?
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Gogl lab @teamgogl.bsky.social · 26/06/2025
Today we got immediate desk rejection .... almost 8 weeks after submission! I think respectful journals could do better than this.
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Bogi @zbobo2.bsky.social · 12/06/2025
I’m thrilled to share that I have secured a permanent position within Section 20 of the CNRS. I will do my utmost to advance our understanding of the intricate interactome of transcription factors, an area of research I am deeply passionate about. 🎆
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Gogl lab @teamgogl.bsky.social · 12/06/2025
Congratulations to Boglarka for obtaining a CNRS permanent position! 🎉🥂 She will start a new line of research in the Gogl lab focusing on the quantitative interactomics and biophysics of protein-DNA interactions and their consequences on transcription regulation and chromatin organization.
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Gogl lab @teamgogl.bsky.social · 10/06/2025
We like our proteins pure. This is the first #mCherry purification in the new lab. The next ones will be less colorful, I am afraid...
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Misha Kudryashev @mishakudryashev.bsky.social · 08/06/2025
We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...
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Gogl lab @teamgogl.bsky.social · 06/06/2025
Snapped the first real Gogl team photo just before our pétanque championship. Spoiler: Bogi won! 🏆 #TeamGogl #newPI
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Gogl lab @teamgogl.bsky.social · 29/05/2025
Every time our team needs to order something important, the university’s response is basically...
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Gogl lab @teamgogl.bsky.social · 27/05/2025
Our brand new iD5 multi mode plate reader arrived from Molecular Devices! I cannot wait to see some data measured on it!
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Juan Reguera @juanrv.bsky.social · 26/05/2025
We are recruiting a junior group leader in computational structural biology. Spread the news! www.nature.com/naturecareer...
nature.com
Junior Group Leader Position in Computational Structural Biology - Marseille (Arrondissement), Bouches-du-Rhône (FR) job with AFMB Laboratory (amU/CNRS/INSERM/INRAe) | 12839733
Junior Group Leader position with a focus on applying artificial intelligence (AI) to the field of integrative structural biology.
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Pedro Beltrao @pedrobeltrao.bsky.social · 02/05/2025
Our work on deriving protein-protein (functional) associations across different human tissues from proteomics data is now published. There is quite a lot in this paper, so I will just touch on a few highlights: www.nature.com/articles/s41...
nature.com
A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes - Nature Biotechnology
Protein–protein interactions specific to 11 individual tissues are presented in a comprehensive resource.
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Varjosalo_Lab @varjosal.bsky.social · 20/04/2025
Short interview hupo.org/Humans-of-HUPO
hupo.org
Human Proteome Organization (HUPO) - Humans of HUPO
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Gogl lab @teamgogl.bsky.social · 28/03/2025
HUGE NEWS FOR THE TEAM - The most amazing Boglarka Zambo just got ranked at #6 in the CNRS N°20 concours. Seems like nothing is stopping her from getting a permanent position this year!
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Gogl lab @teamgogl.bsky.social · 25/03/2025
Our first paper of 2025 is now published in the Journal of the American Chemical Society! The Holdup Multiplex Assay is a powerful approach to measure the affinities of a peptide array against a protein of interest. We apply it for 14-3-3 proteins and PDZ domains. pubs.acs.org/doi/full/10....
pubs.acs.org
Holdup Multiplex Assay for High-Throughput Measurement of Protein–Ligand Affinity Constants Using a Mass Spectrometry Readout
The accurate description and subsequent modeling of protein interactomes require quantification of their affinities at the proteome-wide scale. Here we develop and validate the Holdup Multiplex, a ver...
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Gogl lab @teamgogl.bsky.social · 18/03/2025
Excited to share our latest preprint! We show how the non-catalytic epsilon DNA polymerase subunit, POLE2, binds to NPF motifs proteome-wide! 1/6 www.biorxiv.org/content/10.1...
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Gogl lab @teamgogl.bsky.social · 06/02/2025
Experiments are finally starting in the n̶e̶w̶ ̵l̶a̶b̶ construction site. #newPI
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Ylva Ivarsson @ivarssonlab.bsky.social · 15/01/2025
Looking forward to the monthly on-line seminars organized by the Protein Modules Community @pmc-modularity.bsky.social and talks on SLiMs, systems biology, signaling, computational biology and much more. First talks by Dr Gogl @teamgogl.bsky.social and Dr Dionne @gingraslab.bsky.social.
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Gogl lab @teamgogl.bsky.social · 16/01/2025
I just realized that the new Mendeley version does not work with LibreOffice under Linux anymore. Is there a good alternative? Zotero could work, but I am not a big fan of the 300 MB limit for online syncing. The only option is to pay for extra storage?
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PMC Protein Modules Community @pmc-modularity.bsky.social · 15/01/2025
Join us for our new online seminar series, featuring two talks on protein modules every month! The first session kicks off at 6pm CET Feb 10 with Dr. Gergő Gógl and Dr. Ugo Dionne. Register to attend: tinyurl.com/register-pmc-seminar
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Gogl lab @teamgogl.bsky.social · 14/12/2024
Notes to myself: use a different reference for the next order. (Which may be due in the 2030s...)
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Gogl lab @teamgogl.bsky.social · 04/12/2024
A big step for the lab: we finally got a new centrifuge! It is basic, but it is on our floor and it is going to help us enormously! #newPI
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Varjosalo_Lab @varjosal.bsky.social · 26/11/2024
New work outfit for the lab? 🤔
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 13/07/2024
Don’t let your thesis look like this From the notes @amelierocks.bsky.social and I wrote about writing a thesis 🧪 github.com/KULL-Centre/...
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Gogl lab @teamgogl.bsky.social · 19/11/2024
Please give me ideas! How am I supposed to lift alone this 80kg shaker on top of a bench?
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Gogl lab @teamgogl.bsky.social · 18/11/2024
Hi BlueSky! We study molecular interaction networks by combining #biochemistry #proteomics and #bioinformatics. We are mostly curious about using our quantitative #systemsbiology approaches to characterize motif-mediated protein-protein interactions. #AcademicSky #HiSciSky
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