Despite seemingly low levels of molybdenum (Mo)/tungsten (W) in the Earth’s ancient oceans, these metals play central roles in driving modern biogeochemical cycles. Klos et al. used phylogenomic appro...

Polyamines prevent the action of kinases on acidic phosphorylatable motifs in spliceosomal proteins, thus providing a mechanism for metabolite-mediated regulation of alternative splicing in cells.

Cell fate is shaped by external cues and intrinsic cellular states. While supracellular signals, such as growth factors, provide instructive guidance, emerging evidence highlights the role of cell-aut...