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Evangelia Petsalaki

@epetsalaki.bsky.social
471 followers 237 following 77 posts

Group Leader at EMBL-EBI. Our group uses interdisciplinary approaches including network analysis, omics integration and mathematical modelling to study the context specific regulation of human cell signalling.

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Reposted by Evangelia Petsalaki
Nature Metabolism @natmetabolism.nature.com · 14/08/2026
RESEARCH | A Vidal-Puig & @epetsalaki.bsky.social et al. (U Cambridge, EMBL-EBI) A trajectory-based framework reveals coordinated shifts in metabolic mechanisms in human MASLD 🧪
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A data-driven framework reconstructs the molecular continuum of human MASLD progression - Nature Metabolism
A trajectory-based molecular framework reveals coordinated temporal shifts in metabolic, inflammatory and fibrogenic mechanisms across the human MASLD spectrum.
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Evangelia Petsalaki @epetsalaki.bsky.social · 14/07/2026
Our MASLD paper is finally out @naturemetabolism.bsky.social @ebi.embl.org @opentargets.org ! Fantastic collaboration with Toni Vidal-Puig's group in the IMS, UCam (co-led), Papatheodorou @earlhaminst.bsky.social and other coauthors, led by Ioannis Kamzolas and Thodoris Koutsandreas. Check it out!
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Evangelia Petsalaki @epetsalaki.bsky.social · 10/07/2026
New preprint alert! We integrated plasma proteomics, whole-blood transcriptomics, machine learning and network propagation to dissect high-risk thrombotic primary antiphospholipid syndrome (APS). 🩸🧬https://www.medrxiv.org/content/10.64898/2026.06.26.26356680v1
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Evangelia Petsalaki @epetsalaki.bsky.social · 02/07/2026
Can GNNs really learn biology, or just graph topology? Our new preprint shows that GNNs predict gene essentiality better only when using real biological interaction networks. Biological network organization, not generic graph topology, drives prediction. www.biorxiv.org/content/10.6...
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Reposted by Evangelia Petsalaki
VIB.AI @vibai.bsky.social · 28/05/2026
Last call for our open Group Leader position at VIB.AI and Ghent University! Focus: AI in (bio)medicine Don’t miss this opportunity 👉 vib.ai/en/group-leader-vacancy
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Reposted by Evangelia Petsalaki
The Deliverome Project @deliverome.org · 27/05/2026
Join us: deliverome.org/careers More on the Deliverome Project: ifp.org/the-delivero... Follow along: deliverome.org
deliverome.org
The Deliverome Project
An open receptor atlas for targeted delivery beyond the liver, integrating abundance, specificity, internalization, and routing.
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Reposted by Evangelia Petsalaki
Ewan Birney @ewanbirney.bsky.social · 26/04/2026
Grant writing tips from a grumpy reviewer ploughing through grants. 1. Often your reviewers are going to come from a broad range disciplines adjacent but *not actually in* in your field. Help us get orientated in the summary with an analogy/sketch and go back to analogy / sketch throughout.
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Reposted by Evangelia Petsalaki
Rob Noble @robjohnnoble.bsky.social · 18/04/2026
King's College London are seeking a Lecturer in Applied Mathematics (Quantitative Modelling) to "develop an independent research programme in applied mathematics, mathematical modelling, or a closely related area" www.jobs.ac.uk/job/DRG116/l...
jobs.ac.uk
Lecturer in Applied Mathematics (Quantitative Modelling) at King's College London
Recruiting now: Lecturer in Applied Mathematics (Quantitative Modelling) on jobs.ac.uk. Click for details and explore more academic job opportunities on the top job board
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Reposted by Evangelia Petsalaki
Torsten Schwede @torstenschwede.bsky.social · 13/03/2026
Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬 Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes. The Rule of Thumb: If AF3 can’t model it, we want it.
The Critical Assessment of Structure Prediction (CASP) experiment is calling for prediction targets: Immune Complexes, Organic Ligand-Protein Complexes, Nucleic Acids and Complexes, Conformational Ensembles, Difficult Protein Structures and Complexes. 
Rule of Thumb: If AlphaFold3 can generate a high-quality model, it is likely not a CASP-grade challenge. If it struggles, we want it.
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Reposted by Evangelia Petsalaki
EMBL-EBI @ebi.embl.org · 11/03/2026
We’re recruiting new Research Group Leaders! Why join? 🌍Work across EMBL’s 6 sites 🎓Participate in @embl.org courses and seminars 🔬Lead discovery-driven research in a collaborative environment Apply by 11 April: embl.wd103.myworkdayjobs.com/en-US/EMBL/j... #ResearchCareers @epetsalaki.bsky.social
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Evangelia Petsalaki @epetsalaki.bsky.social · 06/03/2026
Thank you very much for hosting me!
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Evangelia Petsalaki @epetsalaki.bsky.social · 03/03/2026
Our preprint is published in MSB! This time with the correct preprint post below! link.springer.com/article/10.1...
link.springer.com
Integrative multi-omics defines melanoma drug response networks and ARID1A-dependent resistance mechanisms - Molecular Systems Biology
Resistance to BRAF/MAPK inhibitors is a significant challenge in melanoma treatment, driven by adaptive and acquired mechanisms allowing tumor cells to evade therapy. We explored early signaling respo...
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Reposted by Evangelia Petsalaki
EMBL-EBI @ebi.embl.org · 27/02/2026
This #RareDiseaseDay, we’re highlighting how open data sharing supports diagnosis, research, and families living with rare conditions. Watch to find out how access to rare disease data through @deciphergenomics.bsky.social can help families better understand their children’s rare conditions.
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Reposted by Evangelia Petsalaki
Manuel Kaulich @manuelkaulich.bsky.social · 24/02/2026
Our thoughts, impressions, and presentations of the "2nd EuroDepMap symposium" in Milan (Nov 2025) are online at @febsletters.bsky.social. febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com
FEBS Press
Held on 20 November 2025 at Human Technopole in Milan, the 2nd European Cancer Dependency Map Symposium convened experimental and computational scientists to discuss how cancer dependency mapping in ...
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Evangelia Petsalaki @epetsalaki.bsky.social · 19/02/2026
Our preprint is now published in MSB. link.springer.com/article/10.1... We decompose multi-omics into distinct phenotypic axes (drug response vs ARID1A-driven cell state), improving interpretation and revealing how baseline cell state rewires signaling and shapes MAPK inhibitor resistance.
link.springer.com
Integrative multi-omics defines melanoma drug response networks and ARID1A-dependent resistance mechanisms - Molecular Systems Biology
Resistance to BRAF/MAPK inhibitors is a significant challenge in melanoma treatment, driven by adaptive and acquired mechanisms allowing tumor cells to evade therapy. We explored early signaling respo...
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Reposted by Evangelia Petsalaki
Julio Saez-Rodriguez @juliosaezrod.bsky.social · 16/02/2026
Do you want to pursue your ideas in computational biology independently, running your group in @embl.org‘s uniquely collaborative environment, beside world’s most comprehensive biomolecular data resources @ebi.embl.org in Genome Campus next to @sangerinstitute.bsky.social? Apply to join us & share 🙏
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Reposted by Evangelia Petsalaki
IRB Barcelona @irbbarcelona.org · 16/02/2026
📢 This Week at #IRBBarcelona: Join us for a plenary #seminar this Friday, with Dr. @isidrolauscher.bsky.social from @ebi.embl.org @sangerinstitute.bsky.social @cancerresearchuk.org  🤝 Hosted by @nlbigas.bsky.social and @milanlab.bsky.social  Register here ➡️ shorturl.at/imwHx 🧪
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Reposted by Evangelia Petsalaki
Piero Carninci @carninci.bsky.social · 13/02/2026
Looking for bioinformatician for exciting projects across the Centre of Genomics at the Human Technople. We also work with the FANTOM6 Consortium and other international consortia/projects. Details below: careers.humantechnopole.it/job/Bioinfor...
careers.humantechnopole.it
Bioinformatician/Senior Bioinformatician Functional Genomics Research Centre
Bioinformatician/Senior Bioinformatician Functional Genomics Research Centre
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Reposted by Evangelia Petsalaki
Savitski Lab @savitski-lab.bsky.social · 11/02/2026
Rewiring of oncogenic signaling in #DrugResistance is a moving target. In our new study, we used biophysical phosphoproteomics to investigate #BRAF mutant cancer, linking phosphorylation changes to protein function and #MolecularMechanisms through #Multi-Omics integration. tinyurl.com/funsignaling
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Reposted by Evangelia Petsalaki
EMBL-EBI @ebi.embl.org · 10/02/2026
We’re hiring: Research Group Leader in computational biology. Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI. Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j... #ScienceCareers @ewaldlab.org @embl.org
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Reposted by Evangelia Petsalaki
EMBL-EBI @ebi.embl.org · 02/02/2026
Meet Leonie Johanna Lorenz 🇩🇪, a Predoctoral Fellow at EMBL-EBI who is bringing mathematical modelling to microbes. Find out more about how Leonie’s passion for modelling patterns extends from bacterial evolution to sewing 🧵 www.ebi.ac.uk/about/news/p...
Person standing outside next to a building wearing a red jacket
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Evangelia Petsalaki @epetsalaki.bsky.social · 30/01/2026
Indeed an amazing place to start your group! Don't miss the opportunity!
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Reposted by Evangelia Petsalaki
Sharpe Lab @sharpe-lab.bsky.social · 21/01/2026
Pervanadate is more than just a phosphatase inhibitor! Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too. Link: tinyurl.com/5ype7e2s Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3 @babrahaminst.bsky.social
science.org
Pervanadate-induced oxidation relieves autoinhibition of the protein tyrosine kinase SRC
A widely used tyrosine phosphatase inhibitor also oxidizes and activates the tyrosine kinase SRC.
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Reposted by Evangelia Petsalaki
EMBL @embl.org · 22/01/2026
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond. We extend our deepest condolences to his family, friends, and colleagues. www.embl.org/news/people-...
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Evangelia Petsalaki @epetsalaki.bsky.social · 17/01/2026
Truly shocked and saddened by the loss of this brilliant man, scientist and mentor.
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Reposted by Evangelia Petsalaki
Gautam Dey @gautamdey.bsky.social · 07/01/2026
On this day in 2021, I landed in a snowy, lockdown-silenced Heidelberg to start my lab. 5 years later we are a force to reckon with in our field, and the first generation are striking out on their own. I couldn’t be more proud, & grateful to them and our wonderful collaborators around the world 🌍 🧪
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Reposted by Evangelia Petsalaki
Ben Lehner @benlehner.bsky.social · 01/01/2026
Looking to start your lab in generative biology / AI? Come join us at the @sangerinstitute.bsky.social Sanger is core-funded so you can generate data at scale to train the next generation of models and understanding. Design/Engineering/Chemistry/Proteins/Pathways! pls RT tinyurl.com/GenGenFaculty
tinyurl.com
Group Leader - Generative Biology and AI
Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...
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Reposted by Evangelia Petsalaki
Christoph Bock Lab @ CeMM & MedUni Vienna @bocklab.bsky.social · 22/12/2025
HIRING: We recruit PhD students via the AITHYRA-CeMM PhD Program (cemm.at/phd-program). Seeking 3 types of candidates: (1) experimental systems biology in immunity or cancer; (2) bioinformatics & biomedical ML/AI; (3) tech-dev & bioengineering (CRISPR, single-cell, spatial, cell programming) (1/5)
cemm.at
CeMM PhD Program – Molecular Medicine Research in Vienna
Join the CeMM PhD Program in Vienna and pursue cutting-edge research in cancer, immunology, aging, and precision medicine. Applications open in 2025!
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Mile Sikic @msikic.bsky.social · 21/12/2025
1/ We’re hiring PIs in AI × Biology The @astar-gis.bsky.social Genome Institute of Singapore (GIS) is expanding its AI & Computation domain and recruiting junior & senior PIs.
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Reposted by Evangelia Petsalaki
Anastasia Baryshnikova @abarysh.bsky.social · 03/12/2025
Our Human Genetics team @boehringerglobal.bsky.social (Biberach site, Germany) is actively searching for an experienced Statistical Geneticist. #StatisticalGenetics #HumanGenetics #BoehringerIngelheim #ComputationalInnovation #JobOpportunity lnkd.in/g6QPihVE
lnkd.in
Boehringer Ingelheim hiring Senior or Principal Scientist of Human Genetics in Biberach an der Riß, Baden-Württemberg, Germany | LinkedIn
Posted 3:27:12 PM. The PositionAbout us: Computational Innovation @ Boehringer Ingelheim…See this and similar jobs on LinkedIn.
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ICREA Community @icreacommunity.bsky.social · 02/12/2025
From @irbbarcelona.org #ICREAResearcher Patrick Aloy @ptck72.bsky.social has taken part in a study published in @nature.com that broadens the possibilities for designing more effective drug therapies 👇
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Evangelia Petsalaki @epetsalaki.bsky.social · 26/11/2025
#Postdoc alert! We are looking for motivated individual with experience in computational systems biology to join our NetworkCommons initiative to benchmark and democratise network contextualisation methods across multiple applications. Deadline Dec 17th link here: tinyurl.com/yrrzxa94
tinyurl.com
Postdoctoral fellow - Petsalaki Group - NetworkCommons
Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...
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Open Targets @opentargets.org · 26/11/2025
NEW: Postdoc with @epetsalaki.bsky.social @juliosaezrod.bsky.social and Tamas Korcsmáros Benchmark and integrate state-of-the-art network contextualisation methods, combining large-scale transcriptomics, proteomics, and single-cell data Apply by 17 Dec embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com
Postdoctoral fellow - Petsalaki Group - NetworkCommons
Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...
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Reposted by Evangelia Petsalaki
Mikko Taipale @miketilapia.bsky.social · 19/11/2025
We are looking for a postdoctoral fellow to work on induced proximity 🤜🤛 and functional genomics! Join our team in Toronto 🇨🇦 to tackle major challenges in oncology and neurodegeneration. www.nature.com/naturecareer...
nature.com
POSTDOCTORAL FELLOW - Toronto (City), Ontario (CA) job with Taipale Lab, Donnelly Centre, University of Toronto | 12849004
The Taipale lab in the Donnelly CCBR and University of Toronto is looking for a highly motivated Postdoctoral Fellow
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EMBL-EBI @ebi.embl.org · 24/11/2025
Applications closing soon for our internship programme aimed at Master's students at French universities 🇫🇷 Are you studying bioinformatics, computer science or statistics? Check it out! Deadline: 7 December 2025 www.ebi.ac.uk/about/jobs/i... A collaboration with the French Embassy in London.
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 18/11/2025
Do you want to know more on what the PhD with us is about? 🙂 We are still looking for the perfect candidate! 🔎 Please spread the word! 🙏
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Reposted by Evangelia Petsalaki
IGBMC @igbmc.bsky.social · 13/11/2025
The IGBMC is recruiting a new Computational Biology Group Leader through the ENACT AI Chair for Scientific Discoveries, covering cancer, developmental, and structural biology. Join one of Europe’s leading life science centers! cluster-ia-enact.ai/appels-a-pro... Deadline: Jan 7, 2026
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Marco Galardini @mgalactus.bsky.social · 13/11/2025
We are looking to fill a position for computational PhD student, focusing on the development and application of statistical genetics methods to large collections of bacterial pathogens. Have a look at the link for more info. RTs appreciated :) www.microbial-pangenomes-lab.org/2025/11/06/C...
microbial-pangenomes-lab.org
PhD position in bacterial genomics and machine learning available
This is the official web page for the Microbial Pangenomes Lab at Twincore.
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Reposted by Evangelia Petsalaki
Daniel Durocher @durocher1.bsky.social · 13/11/2025
That will be fun to explore!
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Aylwyn Scally @aylwyn-scally.bsky.social · 11/11/2025
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here. www.cam.ac.uk/jobs/faculty...
cam.ac.uk
Faculty Position in Computational Biology
Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied
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Reposted by Evangelia Petsalaki
Denis Wirtz @deniswirtz.bsky.social · 08/11/2025
We have written two reviews providing a practical guide and fundamentals of cell migration: (1) How to select an optimal cell migration assay, (2) How to analyze cell migration data. We also added a perspective on AI methods of analysis. Coming out soon in Nature Methods.
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Omer Ali Bayraktar @bayraktarlab.bsky.social · 11/11/2025
Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...
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Reposted by Evangelia Petsalaki
IMP @impvienna.bsky.social · 10/11/2025
🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
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Jeremy Berg @jeremymberg.bsky.social · 07/11/2025
8 high level positions at NIH posted including 6 institute director positions (NIMH, NIGMS, NICHD, NIDCR, NHGRI, NLM). Only open for 2 weeks (applications due November 21). Application materials include a) CV b) vision statement c) a photocopy of doctoral degree. hr.nih.gov/careers/open...
hr.nih.gov
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EMBL-EBI @ebi.embl.org · 03/11/2025
Bonjour! Masters students in France 🇫🇷, we’ve got an internship for you, in collaboration with the French Embassy in London. Aimed at students of computer science, statistics or bioinformatics. Deadline: 7 December 2025 Find out more and apply: www.ebi.ac.uk/about/jobs/i...
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Ewan Birney @ewanbirney.bsky.social · 10/10/2025
I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com
Staff Scientist
About EMBL-EBI EMBL’s European Bioinformatics Institute is a data powerhouse, utilised on a global scale to advance scientific discovery through bioinformatics and solutions to some of the world’s mos...
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Tina Perica @glukozica.bsky.social · 14/10/2025
Skeetorial on our BRAF preprint! tinyurl.com/asymmBRAF The RAS->RAF->MEK->ERK cascade carries mutations in most human cancers. Interestingly, although we have three RAF paralogues (A, B and C), it is the BRAF that is predominantly mutated in cancer patients. (1/10)
tinyurl.com
Mechanism of MEK1 phosphorylation by the N-terminal acidic motif-mediated asymmetric BRAF dimer
The RAF/MEK/ERK signaling cascade regulates cell proliferation and differentiation and is frequently dysregulated in cancer. Approximately 90% of RAF-mutant cancers harbour mutations in B-type of Rapi...
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BIOMICS_GIMM @biomics-twinning.bsky.social · 14/10/2025
Happening now at GIMM Lisbon 🧠✨ Our "Science meets the Media" workshop is underway - featuring the experienced and inspiring contributions of our collaborators Oana Stroe (EMBL-EBI), Omar Jamshed (CRG), and Sara Sá (GIMM). #BIOMICSproject #GIMM #ScienceCommunication #Bioinformatics #Workshop
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Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 09/10/2025
By Niarakis et al., including: @athinacp.bsky.social @eirini-tsirvouli.bsky.social @hasanbalci.bsky.social @ozanozisik.bsky.social @arnaumontagud.bsky.social @subbannayya.bsky.social @mkutmon.bsky.social Learn about their 5-year plan: www.immunoinformaticsjournal.com/article/S266...
immunoinformaticsjournal.com
Building Immune Digital Twins: An International and Transdisciplinary Community Effort
Digital twins, initially developed for industrial applications, are set to make significant advancements in medicine and healthcare. They have demonstrated promising potential for drug development and...
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James Briscoe @jamesbriscoe.bsky.social · 10/10/2025
The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...
crick.ac.uk
Early career group leaders
We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.
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