iiinova — where your digital self keeps evolving

PMC Protein Modules Community @pmc-modularity.bsky.social · 17/04/2026

Remember to catch out next online seminar on April 20, 3pm CEST!

PMC Protein Modules Community @pmc-modularity.bsky.social · 30/03/2026

Tune in to our next seminar on April 20 at 3pm CEST! We’ll hear from Prof. Tina Perica (@glukozica.bsky.social) and Isabella Menart (@isabellamenart.bsky.social) Register to attend: tinyurl.com/PMCseminar2 Previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 06/03/2026

Don't forget to catch our next seminar on March 9th!

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PMC Protein Modules Community @pmc-modularity.bsky.social · 08/02/2026

We will take a break for February and return on March 9 at 3pm CET. Tune in with Benjamin Maier (@bdmaier.bsky.social), Valeria Bica and Dr Aleksandra Panfilova Register to attend: tinyurl.com/PMCseminar2 Previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 07/01/2026

We are back on Jan 19 at 3pm CET! Our first seminar for 2026 will feature Prof. Benjamin Turk (@benturklab.bsky.social) and Dr. Giorgia Massacci. Register to attend: tinyurl.com/PMCseminar2 Previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 05/12/2025

Don't forget to catch out last seminar of the year on Monday Dec 8!

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PMC Protein Modules Community @pmc-modularity.bsky.social · 14/11/2025

Catch our last seminar for the year on Dec 8 at 3pm CET! With Dr. Martin Rennie (@martinrennie.bsky.social), Jamal Fahoum (@hebrewuniversity.bsky.social), and Dr. Boglárka Zámbó (@zbobo2.bsky.social) Register to attend: tinyurl.com/PMCseminar2 Previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 07/11/2025

Don't forget to tune in to our next seminar on Monday Nov 10 at 3pm CET!

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PMC Protein Modules Community @pmc-modularity.bsky.social · 21/10/2025

Catch our next seminar on November 10 at 3pm CET! You'll see presentations from Prof. Gideon Schreiber (@weizmanninstitute.bsky.social) and Alessandro Lussana (‪‬@alussana.bsky.social). Register to attend: tinyurl.com/PMCseminar2 Recordings of previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 15/09/2025

Tune in to our next seminar on October 13 at 3pm CEST! We’ll hear from Dr. Cris Viéitez (@crisvieitez.bsky.social) and Dr. Patrick Brunner (@humboldtuni.bsky.social). Register to attend: tinyurl.com/PMCseminar2 Recordings of previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 05/09/2025

Remember to tune in to our next Seminar on Monday September 8!

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PMC Protein Modules Community @pmc-modularity.bsky.social · 15/08/2025

We are back with an exciting seminar on September 8 at 3pm CEST! We’ll hear from Prof. Birthe Kragelund and Maximilian Vieler (@uu.se). Register to attend: tinyurl.com/PMCseminar2 Recordings of previous seminars: www.youtube.com/@PMCModularity

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PMC Protein Modules Community @pmc-modularity.bsky.social · 06/06/2025

TIME CHANGE - Because of a public holiday, we have moved the next seminar to Monday June 16 at 3pm CET. Tune in to hear from Dr. Lucía Chemes (@unsamoficial.bsky.social) and Julian van Gerwen (@julianvangerwen.bsky.social). Register to attend: tinyurl.com/PMCseminar2 (1/2)

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PMC Protein Modules Community @pmc-modularity.bsky.social · 24/04/2025

Join us at 6pm CET May 12 for the next seminar in our series with Prof. Tony Hunter (@salkinstitute.bsky.social) and Dr. Jesús Alvardo Valverde (@jesusav.bsky.social). Register to attend: tinyurl.com/PMCseminar2 (1/2)

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PMC Protein Modules Community @pmc-modularity.bsky.social · 15/04/2025

Thanks to everyone who has attended the PMC seminars! We have decided to review the timing of the seminar series. If you have any thoughts about the timing of the seminars (currently 6-7pm CET every 2nd Mon of the month), please fill out this form: forms.gle/VZkU2fWkswxY... Thanks for your input!

forms.gle

PMC Seminar feedback

Thank you for your interest in our seminar series! Whether you've been able to attend or were interested but unable to join us, we value your feedback. Your input will help us improve future sessions ...

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PMC Protein Modules Community @pmc-modularity.bsky.social · 11/04/2025

Remember to join us at 6pm CET April 14 for the next seminar in our series with Prof. Anne-Claude Gingras (@uoft.bsky.social) and Dr. Veronica Venafra. Register to attend: tinyurl.com/register-pmc-seminar You can find recordings of previous seminars here: www.youtube.com/@PMCModularity

youtube.com

PMC Modularity

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Nature Chemical Biology @natchembio.nature.com · 31/01/2025

ARAF uniquely enhances RAS activity via its N-terminal disordered sequence, forming membrane ARAF-RAS condensates that shield RAS from negative regulation and drive cancer drug resistance www.nature.com/articles/s41...

nature.com

Plasma membrane-associated ARAF condensates fuel RAS-related cancer drug resistance - Nature Chemical Biology

ARAF uniquely enhances RAS activity via N-terminal disordered sequence, forming membrane ARAF–RAS condensates that shield RAS from negative regulation and drive cancer drug resistance.

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PMC Protein Modules Community @pmc-modularity.bsky.social · 25/03/2025

Join us at 6pm CET April 14 for the next seminar in our series with Prof. Anne-Claude Gingras (@uoft.bsky.social) and Dr. Veronica Venafra. Register to attend: tinyurl.com/register-pmc-seminar (1/2)

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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 12/03/2025

Our review on machine learning methods to study sequence–ensemble–function relationships in disordered proteins is now out in COSB authors.elsevier.com/sd/article/S... Led by @sobuelow.bsky.social and Giulio Tesei

Figure from the paper illustrating sequence–ensemble–function relationships for disordered proteins. ML prediction (black) and design (orange) approaches are highlighted on the connecting arrows. Prediction of properties/functions from sequence (or vice versa, design) can include biophysics approaches via structural ensembles, or bioinformatics approaches via other hetero- geneous sources. The lower panels show examples of properties and functions of IDRs for predictions or design targets. ML, machine learning; IDRs, intrinsically disordered proteins and regions.

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PMC Protein Modules Community @pmc-modularity.bsky.social · 07/03/2025

Remember to join us at 6pm CET Mar 10 for the next seminar in our series with Dr. Dezső Módos (@imperialcollegeldn.bsky.social ) and Dr. Joanna Koszela (@uofglasgow.bsky.social ). Register to attend: tinyurl.com/register-pmc-seminar (1/2)

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Julia Rogers @juliarurogers.bsky.social · 18/02/2025

Enjoying #BPS2025! I'll present my development of a ML predictor of domain–peptide binding affinity to understand how affinity is optimized across the proteome for cell signaling. Finish out the meeting by coming to my talk tomorrow (Wed) @ 1pm!

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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 06/02/2025

Foldseek-Multimer—now published in @naturemethods.bsky.social—our fast multimer search tool, enables complex comparisons against the full PDB in seconds. It comes with BFMD, a collection of 300K+ predictions gathered from community projects. 📄 nature.com/articles/s41... 🌐 search.foldseek.com

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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 25/11/2024

If you are a PhD student and like protein disorder (or want to learn more), Birthe Kragelund @bbkrage.bsky.social and Kristian Strømgaard are organizing a PhD course on How IDPs work 🧶🧬🧪 Note the cost if you are not at a Danish university. Details: phdcourses.ku.dk/DetailKursus...

Flyer for the course Keeping up with the interactome - How IDPs work including a list of speakers:
Professor Tanja Mittag, St Jude Children’s Hospital, Memphis, US
Professor Kresten Lindorff-Larsen, BIO, SCIENCE, UCPH
Professor Ylva Ivarsson, Uppsala University, Sweden
Dr. Michael Wehr, Systasy Bioscience, Munich, Germany
Professor Zsuzsanna Dostztányi, Eötvös Loránd University, Hungary
Professor Kristian Strømgaard, HEALTH, UCPH
Professor Stefano Gianni, Sprienza University of Rome, Italy
Professor Per Jemth, Uppsala University, Sweden
Dr. Franziska Schöppe, Novo Nordisk A/S, Denmark
Professor Benjamin Schuler, University of Zurich, Switzerland
Professor Alfonse De Simone, University of Naples, Italy
Dr. Malene Ringkjøbing Jensen, CNRS, Grenoble, France
Alleyn Plowright, Chief Scientific Officer, Pangea Bio, London UK
Professor Birthe B. Kragelund, BIO, SCIENCE, UCPH

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EMBL-EBI @ebi.embl.org · 27/01/2025

Kinases play a role in many diseases, making them prime targets for therapeutic intervention. Enter PhosX, a new tool transforming the way researchers analyse and interpret kinase activity. Read the full article: academic.oup.com/bioinformati... @alussana.bsky.social @epetsalaki.bsky.social

academic.oup.com

PhosX: data-driven kinase activity inference from phosphoproteomics experiments

AbstractSummary. The inference of kinase activity from phosphoproteomics data can point to causal mechanisms driving signalling processes and potential dru

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SFB Targeted Protein Degradation @sfb-tpd-vienna.bsky.social · 27/01/2025

Join us in Vienna 8-9 May for the #Ubiquitin & Friends Symposium 2025! Excellent line-up of guest speakers👇And many slots for talks from abstracts, plus flash-talks & posters! Lots of opportunities to network with peers & experts in a friendly atmosphere! ➡️ www.protein-degradation.org/symposium/

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PMC Protein Modules Community @pmc-modularity.bsky.social · 15/01/2025

Join us for our new online seminar series, featuring two talks on protein modules every month! The first session kicks off at 6pm CET Feb 10 with Dr. Gergő Gógl and Dr. Ugo Dionne. Register to attend: tinyurl.com/register-pmc-seminar

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