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Ishier Raote

@ishier.bsky.social
1.1K followers 565 following 357 posts

Institut Jacques Monod, Paris @ijmonod.bsky.social www.ijm.fr/raote-lab Collagen secretion, membrane trafficking Formerly @crg.eu

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Ishier Raote @ishier.bsky.social · 9h
Mine are all coming up at the end of this month. Except they aren't mine, because my name is wrong. So Raote Raote, whomever you may be. Please invite me for the celebration.
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Ishier Raote @ishier.bsky.social · 11h
It does. You click, "import from orcid" and the system takes pages of information, removes the formatting, makes arbitrary changes, and pastes everything into one line - streamlined.
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Ishier Raote @ishier.bsky.social · 12h
Why does filling out a CV on an online portal have to be so tedious? In the end, people only look at the list of publications anyway. Surely there’s a more efficient way to do this! A little less form-filling would be very welcome.
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Ishier Raote @ishier.bsky.social · 17h
Nice preprint from Aki Nakano and Manuel Muñiz! Using SCLIM, they show COPI recycling in yeast occurs during transient cis-Golgi-ERES contacts. Retrograde transport and ER export are coupled - promoting cis Golgi detachment. www.biorxiv.org/content/10.6...
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Stem Cells, Regeneration & Evolution @stemdevevo.bsky.social · 06/10/2026
Happy to share our review on ROS evolution, regeneration and therapeutics, published in Cell Mol Life Sciences. Led by our former PhD student Aurore Vullien, co-supervised with @rottingerlab.bsky.social in collab. with @christinerampon.bsky.social and J. John & E. Amaya. doi.org/10.1007/s000...
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Ishier Raote @ishier.bsky.social · 05/10/2026
Membrane Trafficking Seminar series returns this week with two exciting talks exploring GTPase regulation and the making of lysosomes! Join @felixmendu.bsky.social @franbottanelli.bsky.social and me for an afternoon of fun cell biology. For more details: felixcampelo.wixsite.com/membranetraf...
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Paul Conduit @pconduit.bsky.social · 01/10/2026
Happy to see our latest work published in @jcb.org. Led by an excellent PhD student, Abir Elfarkouchi, and in collaboration with @francoizochsenbein.bsky.social and co-first author Arthur Vitard, we investigated the structural mechanism of CM1 domain autoinhibition rupress.org/jcb/article/...
rupress.org
Journal of Cell Biology | Rockefeller University Press
Journal of Cell Biology (JCB) publishes advances in any area of basic cell biology as well as applied cellular advances in fields such as immunology, neurobiology, metabolism, microbiology, developmen...
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Journal of Cell Biology @jcb.org · 30/09/2026
Abir Elfarkouchi, Arthur Vitard, @francoizochsenbein.bsky.social, @pconduit.bsky.social et al. reveal the first structural model for γ-TuRC CM1 domain autoinhibition, which prevents ectopic binding and activation of #microtubule-nucleating γ-tubulin ring complexes. rupress.org/jcb/article/...
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Mathilda Lennartz @mathilda95.bsky.social · 30/09/2026
UPDATE!: I am absolutely stoked that the second paper of my PhD is now out in @natcellbio.nature.com :D. We combined lipid imaging, STED microscopy, and mathematical modelling in a super cool team effort to quantify lipid partitioning inside clathrin-coated pits. www.nature.com/articles/s41....
nature.com
Quantification of lipid sorting during clathrin-mediated endocytosis - Nature Cell Biology
Lennartz et al. evaluate lipid enrichment in clathrin-coated pits and observe that the differential lipid partitioning into clathrin-coated pits is largely driven by the lipid asymmetry of the plasma ...
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Albert Pol Lab @albertpol.bsky.social · 24/09/2026
Curious how lipid droplets support innate immunity in our cells? Check out our lipidomics by Bosch et al @cp-cellreports.bsky.social! Critical role of LD phospholipids and lipases in supplying defensive w6 arachidonic acid for inflammation and bacterial phagocytosis. www.cell.com/cell-reports...
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Giovanni D’Angelo @giodang.bsky.social · 23/09/2026
#lipidtime: It's a lipid universe. Today in Nature we publish the Lipid Brain Atlas, the first map of membrane lipid composition across the entire mouse brain, a layer of organisation that cell-type and transcript maps had left out. #lipidomics #neuroscience #BrainAtlas
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Ishier Raote @ishier.bsky.social · 22/09/2026
Would that mean that in ChatGPT, we have found the 'Man of the Book'? What a frightful thought.
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Valeria Venturini @valeriaventurini.bsky.social · 22/09/2026
In @pcusachs.bsky.social’s lab at @ibecbarcelona.eu we have a fully founded open PhD position! It’s a very nice working environment & can promise cool mechanobiology🔬🧫 Here all the info ibecbarcelona.eu/predoctoral-...
ibecbarcelona.eu
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Ishier Raote @ishier.bsky.social · 18/09/2026
So. No dissonance at all?
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Endless Screaming @infinitescream.bsky.social · 17/09/2026
AAAAAAAAAAAAAAAAAAAAHHHHHHHHHH
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Fran Bottanelli @franbottanelli.bsky.social · 14/09/2026
#membranetrafficking seminars are back for the fall session! This Thursday two exciting talks from Roger Pons Lanau from @felixmendu.bsky.social lab and @veijosalo.bsky.social #ER #lipiddroplets and lots of wonderful imaging! From single molecules to cryo EM! Please repost
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Veijo Salo @veijosalo.bsky.social · 11/09/2026
Really excited to talk about our recent work next week Thursday in Membrane Trafficking Virtual Community Seminar Series!
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Journal of Cell Biology @jcb.org · 10/09/2026
Stretching the secretory pathway: mechanical control of #Golgi export. Angelika Hausser @angelikahausser.bsky.social highlights new work by Bhaskar Naidu, Vera Lillo, Manneville, Miserey, @felixmendu.bsky.social et al. (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
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Institut Jacques Monod @ijmonod.bsky.social · 10/09/2026
📢 Institut Jacques Monod Seminar 📅 September 18th 📍Institut Jacques Monod Next week, Prof. Omaya Dudin ( @dudinlab.bsky.social ) will present an Institut Jacques Monod seminar on the theme "Exploring multicellular developmental programs at the root of animals and beyond" ➡️ buff.ly/mY66omK
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Ishier Raote @ishier.bsky.social · 09/09/2026
If AI can solve the Navier–Stokes equations and predict protein structures, do you really expect me to believe it can’t find the accursed bicycles or traffic lights?
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Ishier Raote @ishier.bsky.social · 09/09/2026
LLMs starting to solve long-standing problems! ChatGPT: P = NP Me: I think you're wrong ChatGPT: That's correct. I'm sorry. Thanks for pointing it out. P ≠ NP QED.
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sandraduharcourt.bsky.social @sandraduharcourt.bsky.social · 08/09/2026
Very happy to see our Nature Reviews Genetics article on programmed DNA elimination across eukaryotes out! A fantastic collective effort with an amazing group of colleagues, born from inspiring discussions at the Fondation des Treilles. rdcu.be/tmvKgsPZNhBa @laurarossevo.bsky.social
rdcu.be
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Ishier Raote @ishier.bsky.social · 08/09/2026
I do, occasionally, agree with the Spelling Bee team - they allow 'collagen' and reject 'actin'. This is good. Collagen is better than actin.
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Giovanni D’Angelo @giodang.bsky.social · 08/09/2026
Do not miss this fantastic symposium #lipidtime
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Ishier Raote @ishier.bsky.social · 08/09/2026
I'm willing - grudgingly - to accept that Lifeact is not a valid pangram in today's Spelling Bee, but what's wrong with felicitate?!
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Ishier Raote @ishier.bsky.social · 07/09/2026
Join @felixmendu.bsky.social @franbottanelli.bsky.social and me for another season of exciting talks and discussions. Come for the science, stay for the discussions!
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Ishier Raote @ishier.bsky.social · 07/09/2026
Membrane Trafficking Seminar Series 2026 fall season is here! An exciting programme: membrane traffic, organelle biogenesis, lipid transport, endomembrane evolution, we have it all! Save the dates and join us for fun science and discussions. Details at felixcampelo.wixsite.com/membranetraf...
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Jim Hurley @jimhurley.bsky.social · 06/09/2026
The ULK1 complex triggers autophagy on membranes, but with no typical membrane binding domains, how does it get there? See the answer in a brilliant collective effort out now in Science Advances: www.science.org/doi/10.1126/....
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Nick Stroustrup @nstroustrup.bsky.social · 05/09/2026
Did you know that the cells of old animals contain much less mRNA than the cells of young ones? Let me share with you some results from an ongoing project in the lab, where we are finding that a progressive depletion of total mRNA abundance is a crucial part of aging 1/22
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Felix Campelo @felixmendu.bsky.social · 04/09/2026
Many thanks @jcb.org and @angelikahausser.bsky.social for highlighting our recent findings on how the Golgi responds to mechanical forces! As nicely pinpointed out, many (I think exciting and relevant) questions remain open, so I'm looking forward to seeing how this evolves in the next few years!
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Gerry Hammond @gerryhammond.bsky.social · 03/09/2026
I never get bored of watching my favorite lipid, PI(4,5)P2 - especially in real time! In this case imaged with a HaloTag-biosensor and 50 pM JF646.
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Development @dev-journal.bsky.social · 02/09/2026
Collagen remodeling supports Hydra vulgaris head regeneration and stem cell invasion Read this Research Article from our special issue #DevSIextracellular by Ben Cox, Celina E. Juliano and colleagues. journals.biologists.com/dev/article/...
Hydra vulgaris as a model for studying extracellular matrix function during regeneration. (A,B) Whole-mount image of a transgenic Hydra Tg(actin1:GFP)rs1-ec;(actin1:DsRed)rs1-en (also known as ‘Watermelon’) expressing GFP (green) in the ectodermal epithelium (A) and RFP (magenta) in the endodermal epithelium (B). The Hydra body plan consists of an oral end bearing the mouth and tentacles, an aboral end bearing the foot, and a body column connecting the two poles. The region outlined in A indicates the approximate location of the cryosection shown in D. Scale bar in A: 500 μm in A-C. (C) Image of the same Hydra stained with a monoclonal antibody raised against Collagen I (Sarras et al., 1993). Collagen I forms a continuous layer of fibrils along the entire body column. (D) Cryosection of a Watermelon strain Hydra stained with Collagen I antibody, demonstrating that Collagen I forms a distinct layer as part of the ECM that separates the two epithelial cell layers. Scale bar: 100 μm. (E)
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Julian Nüchel @jnuechel.bsky.social · 01/09/2026
Brandnew preprint from @marius-lemberg.bsky.social @bccologne.bsky.social and my lab ! Great to be Part of this collaboration!
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Naba Lab UIC @nabalabuic.bsky.social · 31/08/2026
1/5 📣 Hot off the press: Two papers, one story on the mechanisms of ECM assembly now out in @jcellsci.bsky.social! I am delighted to share two companion studies from our lab exploring the mechanisms of SNED1 fibrillar assembly into the #ECM and how SNED1 shapes ECM architecture and cell phenotype.
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Traffic @traffic-journal.bsky.social · 28/08/2026
Happy 50th anniversary, Clathrin! onlinelibrary.wiley.com/doi/full/10.... @effc.bsky.social
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Mary Munson @marymunson4.bsky.social · 26/08/2026
Structural biology postdoctoral position open in my lab--apply now! For more information about the lab, see www.umassmed.edu/munsonlab/. Interested candidates should apply through the University of Massachusetts Chan Medical School jobs portal (www.ummsjobs.com/job/11668/).
umassmed.edu
Munson Lab | Home | BMB | UMass Chan Medical School
The Munson Lab researches the mechanistic basis for the regulation of spatial and temporal specificity in membrane trafficking in the Biochemistry & Molecular Biotechnology Department at UMass Chan Me...
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Justin Taraska @taraska.bsky.social · 24/08/2026
The Biophysical Society Membrane Fusion, Fission, and Traffic Subgroup is hosting an exciting set of 4 virtual talks on Wednesday September 16th starting at 1 pm Eastern Time on clathrin structure and dynamics. Please join! www.biophysics.org/outreach/sub...
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Max Heiman @heiman.bsky.social · 16/08/2026
For the last year, aECM Club seminars have brought together researchers working on apical ECM in diverse species and tissues - yeast cell wall, C. elegans cuticle, Drosophila lens, mammalian inner ear and pancreatic lumen, and many others. Sign up for 2026-27: forms.gle/DDJUxGLkcSRb...
forms.gle
aECM Club 2026-27
Dear aECM researchers, Thank you for your interest in aECM Club! Feel free to forward this brief survey to any colleagues and trainees who may be interested.
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preLights @prelights.bsky.social · 19/08/2026
Cellularization as a mechanism to build cells. #CellBio #DevBio Supported by @girishkalephd.bsky.social, Anne Ruess highlights a #preprint of @margaridaaraujo.bsky.social et al. @hiralshah.bsky.social @gautamdey.bsky.social @dudinlab.bsky.social #preLight⬇️ prelights.biologists.com/highlights/m...
prelights.biologists.com
Microtubules sustain the fidelity of cellularization in a coenocytic relative of animals - preLights
Cellularization as a mechanism to build cells
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Club Exo Endo @clubexo-endo.bsky.social · 15/08/2026
exoendo.org/en/offre-dem...
exoendo.org
Regulation of organelle function by membrane contact sites
IGBMC, Strasbourg, France -C. Tomasetto
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Böke Lab @bokelab.bsky.social · 12/08/2026
What does an ovary actually look like as it ages—one oocyte at a time? We mapped >85,000 oocytes in >100 intact mouse ovaries, in 3D, across the reproductive lifespan. And the ovary turned out to be much more organized than we expected. 🧵 1/5 www.nature.com/articles/s43...
nature.com
Three-dimensional mapping of intact ovaries reveals the aging dynamics of the ovarian reserve - Nature Aging
The spatiotemporal dynamics of the depletion of the ovarian reserve remain incompletely understood. Combining whole-ovary imaging, AI and modeling, the authors mapped over 85,000 mouse oocytes and fou...
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Ishier Raote @ishier.bsky.social · 12/08/2026
What an amazing, visceral experience it is, to watch the sun quickly and inexorably eaten up by the moon.
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Ishier Raote @ishier.bsky.social · 12/08/2026
Interesting new preprint from Cecile Gauthier-Rouviere! Flotillins link endolysosomes to ERES, recruiting COPII and ATG8 to drive secretory autophagy and extracellular vesicle release. Anew role for COPII in unconventional secretion! www.researchsquare.com/article/rs-1...
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Cell Biology J-Club @cellclub.bsky.social · 03/08/2026
Cooperative definition of ER exit sites by Tango1, Sec16 and Sec12 journals.biologists.com/jcs/article/...
journals.biologists.com
Cooperative definition of ER exit sites by Tango1, Sec16 and Sec12
Endoplasmic reticulum (ER) exit sites (ERES) are dynamic ER subdomains where secretory cargos are concentrated and exported towards the Golgi apparatus. The conserved proteins Sec16 and Sec12 have lon...
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Mukund Thattai @thattai.bsky.social · 01/08/2026
To protest the unending Bangalore roadworks, I created a game called Swalpa Adjust Maadi (Kannada for "please bear with the inconvenience"). You play the contractor digging up the roads, the residents are mute spectators who always lose! A new puzzle each day: mthattai.github.io/Swalpa-Adjus...
mthattai.github.io
Swalpa Adjust Maadi
A game where you dig up Bangalore's roads.
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Liz Miller @lizmillercu.bsky.social · 31/07/2026
Job alert! I'm recruiting a new post-doc to work on mechanisms of co-translational quality control in the ER. Looking for expertise in ribosome biology and yeast genetics/cell biology. Please reach out to me with any questions. www.dundee.ac.uk/work-for-us/...
dundee.ac.uk
Postdoctoral Research Assistant - UOD2336
Closing date: Thursday 27 August 2026, 23:59
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Felix Campelo @felixmendu.bsky.social · 29/07/2026
Very happy to see this #MechanoGolgi story out (and in full open access, thanks to @upf.edu). Thanks a lot to everyone who contributed and helped make this possible, and, hopefully, more to come! rupress.org/jcb/article/...
rupress.org
Mechanical forces stimulate Golgi export
Bhaskar Naidu and Vera Lillo et al. show that extracellular mechanical forces reciprocally regulate Golgi function. By linking cell adhesion and spreading,
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Ishier Raote @ishier.bsky.social · 25/07/2026
I spent ten minutes identifying bicycles to prove to Teams I'm human, only to end up using the audio CAPTCHA. Then, while trying to share my screen, I clicked "Leave meeting" instead. Tried to log back in and... bloody bicycles. Missed half the blasted meeting and now I'm unsure I'm human.
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Julian Nüchel @jnuechel.bsky.social · 23/07/2026
1/10 New preprint alert!🚨 @bccologne.bsky.social @mpiage.bsky.social
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Club Exo Endo @clubexo-endo.bsky.social · 22/07/2026
Save the date! Club Exocytose-Endocytose half-day scientific meeting is planned 📅 1 Dec 2026, 2 pm 📍 Centre Broca Nouvelle-Aquitaine, Bordeaux Neurocampus 🎤 ~8 talks 💻 Hybrid: in person or online Registration & abstract submission open in September. Stay tuned !!
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