Across eukaryotes, the nuclear envelope exhibits distinct remodelling strategies during mitosis: complete breakdown (open mitosis), partial disruption (intermediate), or full retention (closed). Howev...

The kinetochore--the molecular machine that couples chromosomes to spindle microtubules--performs an essential, tightly regulated function, yet varies dramatically across eukaryotes. Microtubules are ...

Cellularization as a mechanism to build cells

Maslennikova et al. identify the ER membrane protein CLCC1 as an interaction partner of the dystonia-linked AAA+ ATPase Torsin1A. Torsin1A sustains the function of CLCC1, which is proposed to facilitate fusion of the nuclear envelope during NPC biogenesis by forming an oligomer that promotes lipid bilayer approach and remodeling.

Epithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...

This study introduces iChIP2, a low-input chromatin immunoprecipitation followed by sequencing method that profiles histone post-translational modifications (hPTMs) simultaneously across diverse eukar...

Cheng, Fan, and colleagues develop CenSegNet, a generalist AI framework for large-scale mapping of centrosome phenotypes, uncovering distinct patterns associated with breast tumour heterogeneity, dise...

The Candidate Phyla Radiation (CPR) represents a bacterial superphylum estimated to include between 15–50% of all bacterial species, yet CPR bacteria remain challenging to culture and have been primar...

Nature Reviews Microbiology, Published online: 08 May 2026; doi:10.1038/s41579-026-01299-7In this Review, Vasse and Velicer explore the phylogenetic and functional diversity of predators of microorganisms, conceptualizing the forms of microbial predation along gradients, including gradients of evolutionary adaptedness for predation and privatization of prey-derived nutrients.

Interested in Expansion Microscopy for your microbial eukaryotes? Through the ExÂME project, we offer free pilot tests to evaluate samples, on-site training workshops in Geneva and Heidelberg, and col...

Increasing evidence suggests that lichens are not just a partnership between one fungus and one alga or cyanobacterium but may contain multiple intera…

Close relatives of animals can become multicellular if distinct individuals join together or if dividing cells remain attached. A species has been found to use both mechanisms.

In a dividing cell, chromosome pairs are pulled apart thanks to attachment sites called centromeres. Yeast genomes reveal key steps in how centromeres have evolved. In a dividing cell, chromosome pairs are pulled apart thanks to attachment sites called centromeres. Yeast genomes reveal key steps in how centromeres have evolved.

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