iiinova — where your digital self keeps evolving

Reposted by Girish Kale

Ran Blekhman @blekhman.bsky.social · 14h

My inbox is being flooded with fully AI-generated emails from prospective students. I tried to work out why I can't bring myself to read them, and ended up with some thoughts and advice for writing cold emails in the age of AI. My new post: blekhman.substack.com/p/why-i-am-n...

blekhman.substack.com

Why I am not reading your AI-generated email

I hope this email finds you well-aligned

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Michalis Averof @michalis-averof.bsky.social · 01/10/2026

A cost-effective method for finding cis-regulatory elements in a large genome (Parhyale, 3.6 Gb), combining info from chromatin accessibility (bulk & single-nucleus ATACseq) and cross-species sequence conservation (low coverage sequencing from 3 additional Parhyale species) Now published in eLife!

elifesciences.org

Genome-wide discovery of cis-regulatory elements in a large genome

Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the em...

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Reposted by Girish Kale

Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026

For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu

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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 24/09/2026

✨ From the beginning of human life to building multicellular systems with synthetic biology! Join Chun So and Benjamin Swedlund for the next VGZT Season 8 session. 📅 Friday, Sept 25 ⏰ 𝟭𝟬:𝟬𝟬 𝗔𝗠 𝗘𝗧 | 𝟳:𝟬𝟬 𝗔𝗠 𝗣𝗧 𝟯:𝟬𝟬 𝗣𝗠 𝗨𝗞 | 𝟰:𝟬𝟬 𝗣𝗠 𝗖𝗲𝗻𝘁𝗿𝗮𝗹 𝗘𝘂𝗿𝗼𝗽𝗲 𝟭𝟬:𝟬𝟬 𝗣𝗠 𝗖𝗵𝗶𝗻𝗮 🔗 Scan the poster’s QR code to join!

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Reposted by Girish Kale

FocalPlane @focalplane.bsky.social · 15/09/2026

Don’t miss the second webinar in our new series on cell migration, featuring talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social. 🗓️Thursday 17 September at 15:00 BST For more info and to register: focalplane.biologists.com/2026/09/03/f...

focalplane.biologists.com

FocalPlane features... cell migration webinar 2 - FocalPlane

FocalPlane features... cell migration webinar 2 - News

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preLights @prelights.bsky.social · 14/09/2026

Hand in hand - E-cadherin with E-cadherin 🤝 Supported by @girishkalephd.bsky.social, Chiara Hüttner highlights work showing that the number of E-cadherin connections influences morphogenetic tissue movements. #preprint Lerchbaumer et al. #TepassLab #preLight⬇️ prelights.biologists.com/highlights/e...

prelights.biologists.com

E-cadherin clustering as a regulator of morphogenesis - preLights

Hand in hand - E-cadherin with E-cadherin: The number of E-cadherin connections influences morphogenetic tissue movements.

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Alfonso Martinez Arias @amartinezarias.bsky.social · 12/09/2026

It is clear that people are using AI to review papers and grants. Often as a tool, not as an off the bottle answer for review (though some do). One of the signs of this is the detail of the negative comments and the errors, often minor and irrelevant to the conclusions. 🧵

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Shefali @iamshef.bsky.social · 11/09/2026

Hey #Drosophila folks - the #flycross #mentee survey is open for #grad students, #postdoc and #pretenure faculty. ~95 mentors from across the world, with diverse expertise. The co-chairs @shyama13.bsky.social and @jocmcdonald.bsky.social have done a phenomenal work in taking the program forward 🎉

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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 09/09/2026

🧬 VGZT Season 8 is starting soon! Check out our 2026 speaker lineup and save the dates for exciting developmental biology talks from around the world. 🌍🤩 Keep an eye on this channel for speaker spotlights and details about each talk! See you all soon! #devbio #gastrulation #cells #models

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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 07/09/2026

🧬✨ VGZT SEASON 8 IS HERE! ✨🧬 Calling all developmental biology enthusiasts 👀 A new season of Virtual Gastrulation Zoom Talks is officially underway, and we have an exciting speaker line-up coming your way! Check out the poster below for everything coming up in Season 8! 👇 #devbio#gastrulation#sci

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Stefano Di Talia @ditalialab.bsky.social · 25/08/2026

We would like to add one or two postdocs to our lab in the next couple of years. If you are close to finishing your PhD and interested in the science we do, feel free to reach out to discuss opportunities.

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The Company of Biologists @biologists.bsky.social · 11/08/2026

We are gathering feedback from our readers, authors and reviewers about the use of AI tools in scholarly publishing. Have your say at: www.surveymonkey.com/r/ZBFC663

Community survey: The role of AI tools in scholarly publishing — announcement from The Company of Biologists, showing five stylized people and three speech bubbles to represent community discussion.

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FlyBase @flybase.bsky.social · 20/08/2026

Treat biological databases as infrastructure, not projects www.nature.com/articles/d41...

nature.com

Treat biological databases as infrastructure, not projects

Letter to the Editor

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Reposted by Girish Kale

preLights @prelights.bsky.social · 20/08/2026

What drives #evolutionary change in early embryonic gene expression? #DevBio Supported by @girishkalephd.bsky.social, bachelor’s student Franziska Traub highlights a recent #preprint of Thomas O'Leary & Brent Lockwood. #preLightsPeerSupport #preLight ⬇️ prelights.biologists.com/highlights/m...

prelights.biologists.com

Modes of natural selection on maternal and zygotic gene expression in Drosophila melanogaster embryos - preLights

What drives evolutionary change in early embryonic gene expression?

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Reposted by Girish Kale

Wolfram Pönisch @wolframponisch.bsky.social · 18/08/2026

Postdoc in my group at @humantechnopole.bsky.social! We want to answer how single-cell morphodynamics is connected to cell topology & state in cell collectives, using data analysis and theoretical modelling. Please share! careers.humantechnopole.it/job/Postdoc-...

careers.humantechnopole.it

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Journal of Cell Science @jcellsci.bsky.social · 07/08/2026

We’re looking for a Reviews Editor to join the team. Joining an experienced & successful journal team, this is an exciting opportunity for a talented scientific editor to make a significant contribution to an important journal in the field of cell biology. www.biologists.com/about-us/wor...

biologists.com

Work for us

Explore career opportunities at The Company of Biologists. Join a team passionate about science, publishing and community support.

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Reposted by Girish Kale

European Commission @ec.europa.eu · 01/08/2026

Japan has now joined Horizon Europe. Japan’s researchers can now partner with teams across the EU. Together, we will advance global research in health, digital technologies, and climate neutrality ↓ link.europa.eu/YP7MtB

Visual featuring Mount Fuji framed by pink cherry blossoms. At the centre are the overlapping flags of the European Union and Japan, with the text "EU-JAPAN HORIZON EUROPE" overlaid below.

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Max Farnworth @maxfarnworth.bsky.social · 23/07/2026

🚨 I am very happy (and relieved!) to announce that I secured Emmy Noether funding by the @dfg.de to start my own group at @unimainz.bsky.social , hosted by Marion Silies & Jakob von Engelhardt in August! 🚨 Website coming soon - open for name/logo suggestions. They better be funny tho!

static.klipy.com

Sophia Petrillo with Megaphone in Golden Girls

ALT: Sophia Petrillo with Megaphone in Golden Girls

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Reposted by Girish Kale

Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 21/07/2026

Final VGZT seminar of the season! 🎉 We're delighted to welcome Cassandra Extavour for our rescheduled keynote lecture: "One, two, three: evolution of developmental counting mechanisms" 🗓️ Thursday, July 23rd  ⏰ 9:30 PDT / 12:30 EDT / 17:30 BST / 18:30 CEST We look forward to seeing you there! 👋

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Reposted by Girish Kale

Mike Dorrity @mwdorr.bsky.social · 23/07/2026

We’re accepting abstracts for QBMM, come join an excellent set of speakers, due early Sept

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The Company of Biologists @biologists.bsky.social · 23/07/2026

Funded places are available for early-career researchers at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins and Giulia Paci @giuliapaci.bsky.social Find out more and apply at www.biologists.com/workshops/ap...

Workshop - Bridging Scales and Disciplines to Understand Robust Development, early-career researchers apply for funded places

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Development @dev-journal.bsky.social · 21/07/2026

In preprints – light, cluster, friction: a cell dance on the gastrulation stage @girishkalephd.bsky.social covers a #preprint that managed something the community has wanted: a method for E-cadherin clustering that forms native clusters that don't seem to get endocytosed. doi.org/10.1242/dev....

doi.org

In preprints – light, cluster, friction: a cell dance on the gastrulation stage

Multicellular organisms, as the name suggests, are composed of many cells that work together. Cells need to stick together to ensure efficient cell coordination. Cadherins, which are calcium-dependent...

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Reposted by Girish Kale

CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · 13/07/2026

📣 #JobAlert The Faculty of Biology of @uni-freiburg.de invites applications for a Professorship (W3) for Bioinformatics and Molecular Genetics. ❗ Application Deadline: 15 August, 2026 🔗 kurzlinks.de/roi8 #Biology #Bioinformatics #MolecularGenetics

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European Drosophila Society @fly-eds.bsky.social · 13/07/2026

📣 📣 📣 📣 To all Drosophilists: the call for Workshop proposals at the 2027 European Drosophila Research Conference in Bonn (20-23 September 2027) is OPEN! Go to link below for instructions. Closing date: 30 September 2026. 👇🏻👇🏻👇🏻 tinyurl.com/45y8trzd

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Girish Kale @girishkalephd.bsky.social · 10/07/2026

As global warming continues, everyone is going to feel its effects, even tiny insect embryos. In this #FluorescenceFriday post, I want to show you what an early fly embryo (Drosophila melanogaster) looks like at an elevated temperature, only 4ºC above the culture temperature. (Details in the 🧵) 1/4

Asynchronous nuclear divisions at an elevated temperature of 29°C in the syncytial Drosophila melanogaster embryo. Nuclei (top panel) and microtubule spindles (bottom panel) in different phases of the nuclear division cycle, visualized using RFP-tagged Histone variant H2Av and GFP-tagged Jupiter, a microtubule-binding protein. Colors indicate distance from the embryo surface; green, 2 µm; cyan, 4 µm; blue, 6 µm; magenta, 8 µm; and red, 10 µm. Imaged on a Zeiss LSM 700 inverted confocal microscope, 63x/1.2 NA water objective; panel size, 203.23x56.73 µm.

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Reposted by Girish Kale

Ankita Jha @ankita13jha.bsky.social · 07/07/2026

Excited to share our new paper, now published in Nature Cell Biology! 🎉 We asked a fundamental question in cell biology: How do cells maintain polarity while migrating? Especially how do cancer cells navigate confined spaces? www.nature.com/articles/s41556-026-01981-1

nature.com

CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration - Nature Cell Biology

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

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Girish Kale @girishkalephd.bsky.social · 07/07/2026

Had a lot of fun revisiting my old love for E-cadherin, writing this In Preprints article. Thanks Daniel @yosoyden.bsky.social for commissioning the article :) Also also, this is my second such article so far! (more yey's for me)

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Girish Kale @girishkalephd.bsky.social · 06/07/2026

Just got this awesome souvenir! Congratulations to everyone involved, especially @thomaslecuit.bsky.social, who has been a steadfast support for a lot of my fly work (even after leaving the lab a few years ago) and more 🙂

Coffee mug back side: pictures of fly embryo, tissue ready for T1 transition, quantification of Convergent extension, neuron, larvae with imaginal disks, fly adult wing. Basically, snippets of work happening in Lecuit lab

Coffee mug front side: 25 years LECUIT Group. Picture of a fruit fly and of tissue invagination

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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 29/06/2026

Exciting VGZT session this week! 🎉 🗓️ Thursday, July 2nd ⏰ 9:30 PDT / 12:30 EDT / 17:30 BST / 18:30 CEST Our speakers are: 👉 Silvia Santos (@santoslab.bsky.social) 👉 Diana Pinheiro (@dianapinheiro.bsky.social) See you there! 👋

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Girish Kale @girishkalephd.bsky.social · 28/05/2026

Our latest manuscript on (Harry Potter and) the effect of elevated temperature on embryonic development in flies. Even a small increase in temperature causes developmental defects, indicating problems in the face of global warming! www.nature.com/articles/s41...

nature.com

Elevated temperature fatally disrupts nuclear divisions in the early Drosophila embryo - Nature Communications

Kale et al. show that nuclear divisions are defective at elevated temperature, leading to gastrulation defects and embryo lethality. Their work finds that F-actin – microtubule interactions during mit...

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The Company of Biologists @biologists.bsky.social · 26/05/2026

Last few days left to submit your idea for a Workshop for our 2028 programme. Send us your proposal by 29 May 2026 at www.biologists.com/workshops/pr... #BiologistsWorkshops

Graphic showing people attending Workshops with headline 'Want to organise one of our Workshops? You focus on the science, we focus on the logistics'

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Reposted by Girish Kale

Emily Gehrels @emilygehrels.bsky.social · 26/05/2026

Interested in the physics that drives morphogenesis? Join us at the Journées de la Matière Condensée October 26 to 30 in Toulouse, France for our session on the physics of morphogenesis in living organisms. jmc2026.sciencesconf.org Talk applications are due May 30th. @sfp-physique.bsky.social

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Girish Kale @girishkalephd.bsky.social · 21/05/2026

Beautiful end of a great conference #CJM26

Sunset at a beach near 'CNRS Le Gulf Stream' hotel, Roscoff

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Development @dev-journal.bsky.social · 20/05/2026

It is a friends of Development reunion: graduated PI Fellows @girishkalephd.bsky.social & @clotilde-cadart.bsky.social, inaugural Preprint Editor @joadelas.bsky.social & Reviews Editor @ingridtsang.bsky.social at the Developmental regulation: from molecular to ecological niches meeting in Roscoff.

From left to right: Girish Kale, Joaquina Delas, Clotilde Cadart and Ingrid Tsang standing in front of the beach at Roscoff.

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Practical Course on Developmental Biology QUINTAY @devbioquintay.bsky.social · 16/05/2026

Please help us to promote the next version of the Developmental Biology course (Quintay Chile). More information in: biodesarrollo.unab.cl

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Development @dev-journal.bsky.social · 15/05/2026

Issue 8 is now complete! On the cover: Embryos of diverse animals & choanoflagellates expressing different fluorescent reporters, from a project to identify membrane-localising tags across diverse organisms. See the Techniques and Resources Article by Karapidaki et al. doi.org/10.1242/dev....

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preLights @prelights.bsky.social · 13/05/2026

What’s new in #DevBio? 👀 Our preLighters Theodora, Jawdat, @sristi.bsky.social & @deevithab.bsky.social have handpicked a selection of exciting preprints in this area. Check out the #preList and let us know your favourite, recent DevBio preprint ⬇️: prelights.biologists.com/prelists/pre...

prelights.biologists.com

preLighters’ choice – Handpicked DevBio preprints - preLights

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Development @dev-journal.bsky.social · 01/05/2026

Meet our Preprint Editors We are pleased to welcome our first group of Preprint Editors to our editorial team, responsible for handling our 'In preprints' articles. #preprints journals.biologists.com/dev/pages/ed...

Clarisse Brunet Avalos, Anchel de Jaime-Soguero, Joaquina Delas, Gwendolyn K. Kirschner, Daniel Ríos-Barrera, Sumeet Pal Singh, Roshana Thambyrajah and Xianfa Yang.

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Institut Jacques Monod @ijmonod.bsky.social · 08/05/2026

📢 Institut Jacques Monod Seminar 📅 May 29th 📍 Institut Jacques Monod Invited by @nkonst4.bsky.social and @maxvcg.bsky.social, Joaquín Navajas Acedo ( @mads100tist.bsky.social ) will present the IJM seminar "Spatiotemporal Emergence of Somatosensory Neuron Diversity " ➡️ buff.ly/1Ityfxj

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Christian Mosimann @chrmosimann.bsky.social · 08/05/2026

Open-rank search: 2 (!) PI positions in Pulmonary Biology at @cuanschutz.bsky.social 🌄 We are looking for new colleagues @cupediatrics.bsky.social, working in lung fibrosis, focusing on #devbio, stem cell, & regen.biology of the lung 🫁🫀. Please help spread the word! cu.taleo.net/careersectio...

cu.taleo.net

Open Rank- Assistant Professor, Associate Professor, or Professor

Click the link provided to see the complete job description.

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Miki Ebisuya @ebisuyamiki.bsky.social · 30/04/2026

We’re looking for a technician to join our lab in Dresden - help manage the lab and work with us on a cool 'stem cell zoo' comparison projects! 🐁🚶‍♀️🦏🐒 Apply by May 21! tud.link/wbqrwm

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Meng Zhu @zhumeng123.bsky.social · 30/04/2026

Cambridge → Boston → Cambridge again: I’m thrilled to return to Cambridge(UK) to open my lab at the Gurdon Institute, University of Cambridge!🥳 (mzhulab.com) We study how dev timing shapes and being shaped by plasticity, evolution & ageing. 🚩Hiring at all levels: pls email me if interested!📩

mzhulab.com

Meng Zhu Lab

We study how development measures time and how timing matters in development, evolution and ageing.

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Alex Eve @amjeve.uk · 28/04/2026

Join us tomorrow to hear two of the three finalists of Development's 2025 Outstanding Paper Prize

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