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Courtney Ellison

@ckellison.bsky.social
222 followers 184 following 8 posts

Assistant Professor at the University of Georgia studying bacterial cell biology 🔬🧫🏳️‍🌈

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Reposted by Courtney Ellison
Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 31/08/2026
Our new paper with @ckellison.bsky.social. is finally out! We identify an ancient and widely conserved mechanism that promotes initiation of fiber polymerization in type IV pili and type II secretion systems.
pnas.org
β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments | PNAS
PilC/PilY1 proteins are tip-located adhesins of type IV pili (T4P) that are critical for T4P function in diverse behaviors including twitching moti...
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Reposted by Courtney Ellison
M. Stephen Trent @mstrent.bsky.social · 10/04/2026
We are recruiting postdocs to work on antimicrobial resistance and bacterial cell envelope biology. PLEASE SHARE.
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Courtney Ellison @ckellison.bsky.social · 26/03/2026
I am pleased to share my lab’s latest publication - Acinetobacter species lack canonical DNA repair pathway activation mechanisms, and we discovered a conserved transcriptional activator that fills this role: academic.oup.com/nar/article/...
academic.oup.com
A WYL transcriptional regulator activates the DNA damage response pathway in Acinetobacter species
Abstract. The ability to sense DNA damage and activate DNA damage response pathways is critical for repairing DNA damage in all domains of life. The most w
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Reposted by Courtney Ellison
Lori L. Burrows @dr-lori-burrows.bsky.social · 11/03/2026
New paper alert! Outstanding work by PhD candidate Nathan Roberge, great collab with the Ellison and Maxwell labs. #Pseudomonas #phage DMS3 encodes Aqs1, an inhibitor of #T4P assembly ATPase PilB, but how it binds and leads to loss of function was unknown. @mcmasteriidr.bsky.social
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Reposted by Courtney Ellison
Yves Brun lab @brunlabcaulo.bsky.social · 26/02/2026
🧵 Proud to present a tour de force by postdoc @gregbwhitfield.bsky.social solving the mystery of how bacterial Tad pili can extend and retract with a single motor ATPase. Great collaboration with Lynne Howell, @dr-lori-burrows.bsky.social, @ianyyen.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Courtney Ellison
Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 16/02/2026
🧵 After years out of the field, I and my lab are again working on bacterial type IV pili. We have just posted our first preprints, and I'm excited to share what we have discovered. This shows Neisseria gonorrheae bacteria infecting a human epithelical cell. Here, you can see the pili in red. 1/
Fluorescence micrograph. Emma Miller and Alex Merz, unpublished.
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Reposted by Courtney Ellison
Lori L. Burrows @dr-lori-burrows.bsky.social · 13/10/2025
New paper alert! We used our fav technique, genetic suppression, to understand how FimX controls function of the T4P PilB motor ATPase in Pseudomonas aeruginosa. Great collab with the Ellison lab at U Georgia who helped with some fancy microscopy to capture pilus dynamics! doi.org/10.1371/jour...
doi.org
Twitching motility suppressors reveal a role for FimX in type IV pilus extension dynamics
Author summary Type IV pili enable Pseudomonas aeruginosa to attach to surfaces, move (twitch), and form biofilms. Pilus extension is powered by the motor protein PilB, which is regulated by other fac...
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Courtney Ellison @ckellison.bsky.social · 22/05/2025
Excited to share the newest preprint from the lab for my first post! Driven by @tayellisonwrites.bsky.social and @ianyyen.bsky.social with Lynne Howell we show the protein FimX has diverged in function away from regulating pilus extension to instead regulate pilus localization in A. baylyi
biorxiv.org
FimX regulates type IV pilus localization via the Pil-Chp chemosensory system in Acinetobacter baylyi
Type IV pili (T4P) are widespread dynamic appendages required for diverse prokaryotic behaviors including twitching motility, biofilm formation, and DNA uptake leading to natural transformation. Altho...
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