Mechanistic understanding of viral protein-protein interactions enables global health security and pandemic preparedness, yet experimental characterisation remains difficult, costly, and often restric...

Coronavirus spike proteins mediate receptor binding and fusion and are key determinants of viral host range. To bind protein receptors, some CoV spikes undergo conformational changes termed opening, w...

Norovirus is the leading global cause of acute gastroenteritis. Here, the authors elucidate norovirus replication and show that the viral NS3 protein forms an RNA-engaging molecular motor that may tra...

The successive emergence of SARS-CoV-2 variants with altered tissue tropism has progressively decoupled transmissibility from lower respiratory tract pathogenicity. Omicron lineages transmit exception...

Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to all European researchers.

Researchers have uncovered new details about a key norovirus protein. They provide a new framework for future research into the virus and antiviral drugs.

Swine are a crucial species in influenza A virus (IAV) ecology, capable of supporting replication and consequently evolution of human, avian, and s...

Hedgehog merbecoviruses utilize hedgehog aminopeptidase N, but not the human orthologue, as their entry receptor. Structural resolution of the glycoprotein–receptor interface reveals the molecular int...

South Australian authorities say case discovered on Kangaroo Island is first for species of which less than 12,000 animals remain * Get our breaking news email, free app or daily news podcast South Australia has recorded the first death of an endangered Australian sea lion from H5 bird flu. Experts say about 12,000 Australian sea lions remain – though a more recent estimate put the figure at less than 10,000. Most of the population are found in South Australia, with the remainder in Western Australia. Continue reading...

There is still limited data reported on virus diversity in South American bats. In this study, the authors report a divergent betacoronavirus with a functional furin cleavage site in South American ba...

The West Nile virus has been confirmed in nine people in the Netherlands since the start of the summer, according to the National Institute for Public Health and the Environment (RIVM). The virus is…

During replisome assembly of monkeypox virus, the hexameric helicase–primase E5 undergoes large-scale conformational changes that allow two of its primase domains to interact with the polymerase F8 th...

Dr. Michael Emerman “You align priorities to favor the trainees (so) that what is good for the trainees will end up being good for the lab” Emerman on successful mentoring, Virology Unm…

De vrouw heeft het virus in Nederland opgelopen en kreeg daarna hersenvliesontsteking, meldt stadsomroep AT5.

About 175 students and supervisors from Breda University of Applied Sciences fell ill during an orientation camp in Belgium.

Register here for the Cryo-EM Symposium 2026, 24-25 September at the IMP, Campus-Vienna-Biocenter 1, 1030 Vienna.Please select the applicable registration fee and add it to the cart. Please click on t...

Liang et al. show how enterovirus D68 uses the respiratory receptor MFSD6 and sugar modifications to enter cells, revealing a checkpoint that primes the virus for infection.

Characterization of the human coronavirus HKU1 is limited due to a lack of infection models. Here, the authors develop a cell model to propagate HKU1 and show that, unlike its relative SARS-CoV-2, it ...

Nature Microbiology, Published online: 26 August 2026; doi:10.1038/s41564-026-02470-9A genomic screen reveals homologues of ESCRT components in mirusviruses that infect unicellular aquatic eukaryotes.

In de provincie Utrecht is iemand overleden aan westnijlkoorts. De persoon liep het westnijlvirus in Nederland op en overleed in een ziekenhuis. Het RIVM doet vanwege de privacy van en uit respect voor de nabestaanden geen verdere uitspraken over deze persoon.

Programmed −1 ribosomal frameshifting (PRF) is a translational control mechanism used by RNA viruses to regulate the relative abundance of proteins en…

Genome-wide mapping of RNA structure in murine norovirus reveals structural elements whose disruption impairs viral replication in cells and in vivo. Such structural disruptions generate a genetically...

Genetic variation in viruses is well known to arise from polymerase-driven nucleotide misincorporation. However, insertion and deletion (indel) mutations that occur at lower, largely unknown, frequenc...

COVID-19 and previous pandemics have shown how diseases can disrupt, threaten, and transform daily life. Since pathogens and societies are continuously evolving, every pandemic is different. However, ...

Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that threatens swine health and poses a potential risk of cross-species transmission; however, effective countermeasures remain limi...

Author summary Rhinoviruses (RVs) are highly prevalent respiratory viruses that frequently cause common cold symptoms. For people with chronic lung disease such as asthma, infection can cause signific...

Communications Chemistry, Published online: 06 August 2026; doi:10.1038/s42004-026-02151-yViral proteases are key targets for developing direct-acting antivirals to combat infections like SARS-CoV-2. Here, the authors synthesize macrocyclic α-ketoamide inhibitors, demonstrating potent inhibition of SARS-CoV-2 and enteroviruses, highlighting macrocyclization’s potential to enhance antiviral efficacy and achieve broad-spectrum activity.

Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...