Applications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu...

Increased expression of EBV reactivation genes in B cells and MS risk genes targeted by the EBV protein EBNA-2 precedes MS attacks, linking EBV reactivation and genetic risk to the development of MS r...

Wallenberg Academy Fellow Carmen Gerlach is breaking new ground in her view of the immune system’s T cells. Instead of dividing them into groups, she is studying how individual cells develop their uni...

Human induced GC-like B (iGCB) cells are generated in vitro from circulating naive or marginal zone cells.

New study from PLOS Global Public Health reveals bovine TB costs rural Zambian farmers ZMW 10 per infected cow daily in lost milk production, while older res… #Bovinetuberculosis #Ruralhealth #Tuberculosiscontrol #Zambia #Zoonoticdisease

New study from PLOS Global Public Health reveals bovine TB costs rural Zambian farmers ZMW 10 per infected cow daily in lost milk production, while older res… #Bovinetuberculosis #Ruralhealth #Tuberculosiscontrol #Zambia #Zoonoticdisease

A large number of individuals with tuberculosis (TB) are asymptomatic. Here, the authors characterise blood transcriptomic and proteomic profiles in South African community screening cohorts to identi...

Breast cancer is often classified as either estrogen receptor-positive (hormone-sensitive) or not. However, a new study from Karolinska Institutet suggests that this simplified classification may over...

The slow growth displayed by Mycobacterium tuberculosis has been historically associated with pathogen’s persistence and drug tolerance. Unexpectedly, here the authors identify a rare subpopulation of...

Scientists share help and advice on how they got their research discussions flowing.

Lymph nodes initiate protective T cell responses to Mycobacterium tuberculosis yet also serve as sites of chronic infection. Shamskhou et al. shed light on this paradox by showing a shift from early d...

According to the Democratic Republic of the Congo (DRC) Deputy Director of the National Malaria Control Program (PNLP), the country saw about 26 million malaria cases and 30,000 deaths in 2025.

Spatiotemporal environmental variation results in marked heterogeneity in bacterial infection progression and disease outcome, with vital consequences for treatment success. For the globally important...

Dissecting protective versus detrimental immune responses uncovers biomarkers and mechanisms that can inform the rational design and evaluation of live attenuated vaccines against African swine fever...

Eli Lilly has splashed up to $3.8 billion on an infectious disease pipeline,

Why the continent accounts for the overwhelming majority of cases...

Ebola virus disease (EVD) is caused by the filovirus Ebola virus (EBOV). Although the natural host of EBOV is undefined, a single zoonotic transmission is the probable start of most EVD outbreaks. EVD...

The Centers for Disease Control and Prevention’s decision to end its monkey research program will affect studies involving some 200 macaques, and the fate of the animals is unclear

Introduction of the RTS,S malaria vaccine in routine immunisation programmes was associated with a significant reduction in mortality in young children, averting about one in eight deaths, in areas wi...

Nature Communications - Here, the authors show that IFNγ blockade does not impair resistance to Mycobacterium tuberculosis infection in macaques, opposed to what has been observed in mice, due...

The number 17 is considered unlucky by some Italians as its Roman numerals – XVII – can be rearranged as Vixi, a Latin expression that can be interpreted as “my life is over”. In other contexts, the n...

Variation in antibody genetics, as illustrated in the accompanying paper by Corcoran et al., can present a challenge to the development of population-wide protective vaccines. Fischer, Corcoran, et al...

Inherited variations in antibody genes can affect how we respond to infections and vaccines, show two new studies from Karolinska Institutet published in the journal Immunity. The researchers have map...