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Kerry Hilligan

@kerryhilligan.bsky.social
1.2K followers 594 following 12 posts

Immunologist with an interest in respiratory infectious disease 👩‍🔬🔬 🫁 Team Leader @ Malaghan Inst 🇳🇿 🥝 Sher lab alum @ NIH 🇺🇸 Proud dog & cat mum🐱🐶🐶 Views are my own she/her scholar.google.com/citations?user=e…

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Kerry Hilligan @kerryhilligan.bsky.social · 06/12/2025
Calling all lung immunology enthusiasts 🫁 I’m excited to share this project where we designed and optimised a spectral cytometry platform to study immune responses in the mouse lung at steady-state and during viral infection. We hope this will be a useful resource for the field! Link below 👇
currentprotocols.onlinelibrary.wiley.com
Spatially Resolved Immune Profiling of the Murine Lung Using In Vivo Labeling and Spectral Cytometry
The lung is a structurally and immunologically complex organ, constantly exposed to airborne microbes, allergens, and pollutants. Understanding how diverse pulmonary immune cells respond to these cha....
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Steve Turner @sjturn.bsky.social · 04/12/2025
Now up in the Thursday Plenary @kerryhilligan.bsky.social the #ASI2025 the Peter Doherty medal recipient, celebrating research excellence by ECRs
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Dr. Dawn Bowdish @msmacrophage.bsky.social · 04/12/2025
Congratulations to @kerryhilligan.bsky.social for her Doherty Lectureship for her most excellent body of work studying tissue immunity to infections. #ASI2025 #PerthASI
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Michelle Linterman @linterman.bsky.social · 22/05/2025
Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...
doi.org
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this article for the Highlights of 2024 series, we review the latest advances in the biology of the germinal center response. These discoveries provide key insights into germinal center function a...
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Journal of Experimental Medicine @jem.org · 18/03/2025
@kerryhilligan.bsky.social et al @niaidnews.bsky.social review the evidence that both the mycobacterial-specific & off-target nonspecific effects of BCG immunization require the interplay of innate & adaptive responses, the elucidation of which could improve #TB vaccines rupress.org/jem/article/...
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Arthur Mortha @theonlylabever.bsky.social · 19/12/2024
Ever wondered how gut microbes control immune responses at extra-intestinal locations? Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria. @cellpress.bsky.social ⬇️(1/x) www.cell.com/cell/fulltex...
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ImmunoSketch @actuallypublished.bsky.social · 12/12/2024
Lungs primed by past infections, like enriched soil, resist COVID-19 better, revealing why outcomes vary. @mayerbarber.bsky.social @pauljbaker.bsky.social @kerryhilligan.bsky.social @danbarberphd.bsky.social @niaidnews.bsky.social @sciimmunology.bsky.social t.co/5L7vmTbsNN #ImmunoSky 🧪
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Rebecca Palmer @rsjpalmer.bsky.social · 11/12/2024
Had a great time presenting my poster at ASI2024 Sydney Australia! We’re studying how the lung’s cellular landscape shifts during infection and influences future infections, using high-dimensional flow cytometry to profile and characterise pulmonary cells at steady state and during infection! 🫁
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Paul Baker @pauljbaker.bsky.social · 07/12/2024
Excited to share this paper from my post-doc at @niaidnews.bsky.social out now in Science Immunology! We show that recent or ongoing 🫁 infections or other pulmonary environmental exposures at the time of infection with SARSCoV2 can vastly influence early replication of the virus in mice.
science.org
The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication
Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.
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Kerry Hilligan @kerryhilligan.bsky.social · 06/12/2024
Super privileged to have been apart of this amazing tour-de-force study from @pauljbaker.bsky.social, @mayerbarber.bsky.social and team showing how inflammatory history of the 🫁 alters susceptibility to #covid19. Congrats team!! 🎉🎉
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Kat Mayer-Barber,PhD @mayerbarber.bsky.social · 06/12/2024
Best #Nikolaus 🎅! Our paper on how the 🫁 microenvironment can shape #innate immunity against #viruses is out @sciimmunology.bsky.social This was a herculean effort brilliantly led by @pauljbaker.bsky.social who singlehandedly established the model in the lab during the pandemic. 🧪 #Immunosky 1/9
Graphical summary of our paper.  In mice, prior lower airway exposure to diverse inflammatory stimuli, including chronic bacterial infections such as M. tuberculosis, acute bacterial infections such as pulmonary S. aureus, viral infections such as Influenza A, type-II allergic responses such as the OVA-Alum model, activation of pulmonary TLR9 by CpG or pulmonary TLR1/2 by Pam3CSK4
 leads to reduced viral burden upon subsequent infection with SARS-CoV-2 (SCV2). (2) This SCV2 restriction occurs prior to induction of SCV2-specific adaptive immune responses 
and is mediated through innate immune responses, including the induction of IFN-I, TNFα and IL-1 and sustained changes to the TRM (Tissue resident macrophage) cellular 
compartment and the pulmonary epithelium. (3) Innate cytokine and TLR signaling to both recruited immune cells and the pulmonary epithelium creates a microenvironment in the 
lung that limits early replication of SCV2. IFN-I signaling to pulmonary ECs (epithelial cells) increases expression of interferon-stimulated genes, that likely cell-intrinsically limit viral
 replication. TNF- or IL-1 suppress SCV2 independently of IFN-I signaling. TNF acts exclusively through radio-resistant cell types such as the lung epithelium, whereas IL-1 affords 
control both direct and indirectly, through either stromal and hematopoietic cell types, to restrict overall early SCV2 burden.
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Waggoner Lab @labwaggoner.bsky.social · 06/12/2024
Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2 www.science.org/doi/10.1126/... @sciimmunology.bsky.social @mayerbarber.bsky.social
science.org
The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication
Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.
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Natalia Sampaio @drnatsampaio.bsky.social · 06/12/2024
Resharing this for those new to bluesky. If you are interested in #innateimmunity or #inflammation, here’s a starter pack or researchers to follow! Leave a comment if you wanna be added too. #immunosky #academicchatter go.bsky.app/QqJ9AgB
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ImmunoSketch @actuallypublished.bsky.social · 04/12/2024
A starter pack for PhD students and Postdocs in Immunology to connect 🔽 Drop a 🧬 and I'll add you to the list. Let's build the upcoming immuno community! #ImmunoSky 🧪 go.bsky.app/RABVXY4
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Lucille Rankin @lucillera.bsky.social · 20/11/2024
go.bsky.app/7zMmwNY Hi all, so nice to cross over to the light. Here is a starter pack for all things Mucosal Immunology! Exciting to create a MI community here. Let me know if you would like to join 👍
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Dr Danika Hill @precisionvaxlab.bsky.social · 03/12/2024
I’ll take this opportunity to announce that I’ll have multiple postdoc positions opening early next year. Come join us in Melbourne! 🇦🇺🐨🦘 If you’re interested in mucosal immunology, microbiology, parasitology, vaccine design or bioinformatics, get in touch ✉️! #ImmunoSky #MicroSky #IDSky
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Eric Topol @erictopol.bsky.social · 02/12/2024
Strong new evidence for T cell exhaustion in myalgic encephalomyelitis (ME/CFS) reflecting chronic viral infection, relevant to #LongCovid, and possible path to treatment candidates www.pnas.org/doi/epub/10.... @pnas.org
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Rod Rahimi @rodrahimi.bsky.social · 29/11/2024
Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/6aT6qDS go.bsky.app/QSEPDoj
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Andrew S. MacDonald @profandrewmac.bsky.social · 29/11/2024
Fascinating new paper about how commensal #fungi can promote #type2 responses in mice, a process involving fungal induction of #IL-33 🍄 🧪 #ImmunoSky www.nature.com/articles/s41...
nature.com
Fungal symbiont transmitted by free-living mice promotes type 2 immunity - Nature
Kazachstania pintolopesii is a highly prevalent fungal symbiont that can trigger type 2 immunity and influence the composition of the gut mycobiome, as well as immune and disease phenotypes.
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Ellen Foxman @ellenfoxman.bsky.social · 25/11/2024
The measles vaccine is given as a shot but it is surprisingly good at inducing protective immunity in the respiratory tract (mucosal IgA). Our new study provides some clues about why...a thread (1/8) #IDSky #MedSky #lungs #immunology #ImmunoSky academic.oup.com/jid/advance-...
academic.oup.com
Validate User
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Nonia Pariente @npariente.bsky.social · 22/11/2024
Hi Bluesky! 👋 Dipping my toes here given the dumpsterfire over at X. I am Editor in Chief of #PLOSBiology, interested in all things #science. #virologist, passionate about #OpenScience & making #publication process constructive & transparent. I look forward to rebuilding community here!
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Carolyn King @immunologyking.bsky.social · 19/11/2024
we love #tcell #immunology but are steadily starting to swoon in the world of lung #macrophages. is no marker sacred? 😂 Ly6G+ macrophages? CD64+ #neutrophils? pubmed.ncbi.nlm.nih.gov/39093958/ pubmed.ncbi.nlm.nih.gov/38844208/
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Nicole Campbell @drnicolecampbell.bsky.social · 20/11/2024
👋 fellow immunologists, it’s a pleasure to be with you all on bsky! I work on type I #interferons, I figured it would be neat to have a starter pack for those of us working on all things IFN! I’ll keep adding to it, let me know if you want to be included! #immunology #immunosky go.bsky.app/71vKZJA
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International Cytokine & Interferon Society (ICIS) @cytokinesociety.bsky.social · 18/11/2024
🦋 We're in the process of moving here from X. Join us, follow & share your research & publications (cytokine related or outside the boundaries, published or pre-pub), job openings, meetings & informal gatherings where great ideas are born & cultivated @cytokinesociety.bsky.social
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Rod Rahimi @rodrahimi.bsky.social · 19/11/2024
Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network Below are the links If you're an immunologist and I have missed you so far, let me know 🧪 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/6aT6qDS
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Tobias Hohl, MD PhD @fungalspore.bsky.social · 17/11/2024
go.bsky.app/2bqX3T7 - please send me your @bsky.app handles to include in this growing community.
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Natalia Sampaio @drnatsampaio.bsky.social · 16/11/2024
I’ve made a Starter Pack of #innateimmunity and #inflammation researchers to follow! Please contact me to get added or to suggest others to add. We are just getting started 😎 #immunosky #academicchatter go.bsky.app/QqJ9AgB
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