The protein landscapes that underlie multicellular self-organization remain challenging to characterize across intact embryos at high spatial resolution. Here, the authors present 3D-4i, a high-throug...

The 2026 call has attracted considerable interest from the research community with 21,627 applications submitted.

Letting powerful academics off the hook and punishing the people they bullied sends the message that abuse is acceptable in academia.

Online course in placental biology - 14th to 18th September 2026 Registration open 2026_pcb_advertisement_material_banner.jpg This online course is aimed at students, post-docs, established…

Human embryonic development proceeds more slowly than in mice. The segmentation clock offers a tractable model for studying species-specific developme…

The spatiotemporal dynamics of the depletion of the ovarian reserve remain incompletely understood. Combining whole-ovary imaging, AI and modeling, the authors mapped over 85,000 mouse oocytes and fou...

Accelerated limb formation in marsupials reveals canonical developmental landmarks aren’t strict prerequisites for initiation.

Before Hydra can regrow a head or foot, its cells appear to rebuild the internal map that tells them where they are and what they should become next, FMI researchers report. The work suggests that cel...

Because of their ability to simulate certain aspects of embryonic development, stem cell-based embryo models can be a promising tool in our efforts to better ...

A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.

Summary: A reaction-diffusion mechanism recapitulates pattern emergence in an in vitro model of neuromesodermal progenitors under a variety of boundary and geometrical perturbations.

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

He, Wang, Ding and colleagues report a transcriptomic atlas of human female reproductive tract segments from fetuses at gestational weeks 10 to 25.

During embryogenesis, cell types arise in a predictable order because developmental regulators act sequentially. But how evolutionary changes in morphogenesis reshape the signaling environments that a...

Mouse and human data suggest ovaries develop a new function after reproductive duties end

Di Carlo and colleagues discuss technologies required to map and engineer the human cell–cell interactome and the therapeutic avenues such an atlas could unlock.

Rigidity transitions govern tissue organization in ways reminiscent of inert materials. Yet, living tissues are composed of active units with autonomous timing mechanisms, raising the question whether...

Tissue phase transitions are key to morphogenesis. Now adhesion-driven rigidification is identified as key to epithelial organization but only if uncoupled from density-driven jamming.

Multinucleate cells — single cells containing multiple nuclei in a shared cytoplasm — are found across the eukaryotic tree of life. Having evolved ind…

Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...