Compartmentalisation enables cells to spatially organise essential biochemical processes. This is exemplified by the eukaryotic nucleolus, which concentrates the machinery for ribosome biogenesis. Bac...

CRISPR-Cas provides RNA-mediated adaptive immunity, but how its first RNA-guided effector arose is unclear. In this study, we report the discovery of Viral Interference Programmable Repeat (VIPR) syst...

Study shows that the venerable device does not waft bacteria away from workbenches, as is often assumed.

All living beings use ribosomes to synthesize proteins from α-amino acids. Inherited from our common ancestor, a few universally conserved ribosome biogenesis steps, introducing essential ribosomal RN...

LMU-Forschende haben einen Mechanismus aufgedeckt, der seit mehr als 700 Millionen Jahren die Konzentration von Häm in der Zelle überwacht.

ChimeraX Volume Operations Simplified Edition . Contribute to jparmachelab/ChimeraX-VOSE development by creating an account on GitHub.

Parmi les 66 projets sélectionnés par le Conseil européen de la recherche, Anthony Henras et l’équipe EukaRiBio (MCD-CBI) sont lauréat d’un des 13 projets du

Nature Methods - ROCKET improves experimental structure elucidation by integrating implicit structural knowledge from OpenFold, a trainable reimplementation of AlphaFold2, with X-ray...

Excessive RNA damage activates cellular stress responses, triggering cell death. However, pathways that negatively regulate RNA damage responses are l…

Nature Communications - N-terminal histone acetylation by human NAA40 alters epigenetic signaling and affects gene regulation. Here, the authors combine biochemistry and cryo-EM to unravel the...

The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.