iiinova — where your digital self keeps evolving

Reposted by Terry Zhang

Swiss National Science Foundation (SNSF) @snsf.ch · 22/09/2026

🏆 Biochemist Martin Jinek is the winner of the Swiss Science Prize #MarcelBenoist 2026, considered the Swiss #Nobel Prize. He contributed to the development of molecular scissors, namely CRISPR-Cas9 technology. Read more ➡️ sohub.io/3hs4

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Terry Zhang @terryzzy.bsky.social · 20/09/2026

Check out our work! We found a bizarre code when tracing the evolution of CRISPR immunity.

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Reposted by Terry Zhang

Kenneth Loi @kenjmloi.bsky.social · 18/09/2026

VIPR is now out in Science! What started with a mysterious RNA led us to an unexpected way of recognizing DNA, as well as some clues to CRISPR’s origins. So happy to share these two papers with an incredible team. Links below; original discovery thread here ↓

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Reposted by Terry Zhang

Doudna Lab @doudna-lab.bsky.social · 09/06/2026

We now present our latest work, now out in @nature.com! A creative new CRISPR-based approach can selectively destroy cells carrying undruggable mutations in cancer. Work led by @jingkunzeng.bsky.social In collaboration with Alan Ashworth, Yang Liu and Ryan Jackson. www.nature.com/articles/s41...

nature.com

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding - Nature

Nature - Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding

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Reposted by Terry Zhang

Kranzusch Lab @kranzuschlab.bsky.social · 12/06/2026

How do human cells defend against viruses? @sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics www.biorxiv.org/content/10.6...

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Reposted by Terry Zhang

Alex Gao @algao.bsky.social · 16/04/2026

Excited to share our new findings in @science.org on how the DRT3 bacterial defense system uses a reverse transcriptase that builds DNA repeats without a nucleic acid template. Microbes never cease to amaze! www.science.org/doi/10.1126/...

science.org

Science | AAAS

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Reposted by Terry Zhang

Cress Lab @cresslab.bsky.social · 30/04/2026

Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.

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Reposted by Terry Zhang

Kenneth Loi @kenjmloi.bsky.social · 27/04/2026

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

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