iiinova — where your digital self keeps evolving

Reposted by Jean-Paul Armache

Jean-Paul Armache @valendraica.bsky.social · 08/07/2026

If you or someone you know is interested in joining a fun and productive lab (JP Armache laboratory at Penn State University) to work on exciting projects, please follow or share the link below. psu.wd1.myworkdayjobs.com/PSU_Academic...

psu.wd1.myworkdayjobs.com

Postdoctoral Position

APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

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Jean-Paul Armache @valendraica.bsky.social · 21/08/2026

Please see and help spread the word about the ‘call for papers’ in BMC Methods, guest edited by my colleague at the Penn State’s Center for Eukaryotic Gene Regulation, Dr. Lu Bai.

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Reposted by Jean-Paul Armache

Dr. Roberta Dollinger @robertadolling1.bsky.social · 20/08/2026

Check out our new paper! We did Cryo-EM on native Pol II elongation complexes isolated from Drosophila embryos. This was an incredible collaboration across multiple labs and is now available for your perusal. 👇 www.nature.com/articles/s41...

nature.com

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Jean-Paul Armache @valendraica.bsky.social · 08/07/2026

psu.wd1.myworkdayjobs.com

Postdoctoral Position

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Jean-Paul Armache @valendraica.bsky.social · 14/06/2026

We are sharing a tool developed initially for internal use called VOSE (Volume Operations Simplified Edition) today. It is written specifically to work in ChimeraX (version 1.5+), with no additional libraries necessary to be installed. github.com/jparmachelab...

github.com

GitHub - jparmachelab/ChimeraX-VOSE: ChimeraX Volume Operations Simplified Edition

ChimeraX Volume Operations Simplified Edition . Contribute to jparmachelab/ChimeraX-VOSE development by creating an account on GitHub.

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Jean-Paul Armache @valendraica.bsky.social · 16/01/2026

A wonderful collaboration between Jess Tyler lab, @epicypher.bsky.social, @gcloner.bsky.social, James Kadonaga and our lab at PSU. In this article, we provide the significance of the nucleosome acidic patch. doi.org/10.64898/202...

doi.org

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Reposted by Jean-Paul Armache

Karim-Jean Armache @kjarmache.bsky.social · 17/10/2025

Honored to be named the Laura and Isaac Perlmutter Endowed Chair in Biochemistry at NYU Grossman School of Medicine. Grateful to my mentors, lab members, and the NYU community—and most of all, to my amazing family for their constant support!

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Jean-Paul Armache @valendraica.bsky.social · 05/02/2025

We did a thing... We purified native transcriptional complexes from Drosophila embryos, obtaining +/- stalk Pol II elongation complexes, native nucleosomes, as well as a nucleosome elongation complex. For more details please check out: doi.org/10.1101/2025...

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Reposted by Jean-Paul Armache

Karim-Jean Armache @kjarmache.bsky.social · 13/11/2024

Please see our paper in Nature on read-write mechanisms of H2AK119 ubiquitination by Polycomb repressive complex I. Congrats to the whole team, especially Victoria and huge thanks to our collaborator JP Armache! Also big thanks to Mark Foundation for Cancer Research for the support! rdcu.be/dZ5HZ

rdcu.be

Read–write mechanisms of H2A ubiquitination by Polycomb repressive complex 1

Nature - Cryo-electron microscopy and biochemical studies elucidate the read–write mechanisms of non-canonical PRC1-containing RYBP in histone H2A lysine 119 monoubiquitination and their...

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