📣 Congrats to the Stigler lab on their new publication! 👏 🥂
Their findings provide fascinating mechanistic insights into how the chromatin remodeler INO80 searches DNA and establishes chromatin organization at promoters and replication origins.
Find the details here:
doi.org/10.1038/s414...
doi.org
Single-molecule imaging reveals DNA shape read-out by the INO80 chromatin remodeler - Nature Communications
How chromatin remodelers regulate nucleosome positioning remains poorly understood. Here, the authors use single-molecule fluorescence microscopy to reveal how read-out of DNA shape features regulates...
